/*
LPL Model Sample Input File: Radiosensitivity parameters correspond to an alpha/beta ratio of 1.62 Gy. The half-time for DSB repair is ~ 2.0 hour. The entire cell population is actively dividing (exponential growth kinetics), i.e., GF=1.  In addition to the radiation damage, endogenous processes are presumed to create 4.33E-03 DSB/cell-hour.
*/
   MODEL: DRM=LPL CKM=QECK         !Model Specification
   CELL: DNA=5.667D+09 NC=46
   ENDO: DSB=4.3349E-03                         !Endogenous DNA damage
   IRAD: DSB=25 FL=0.1                          !Radiation damage to DNA
   CLRP: LAM=0.347 ETA=2.75E-04 GAM=0.25 B0=0.25
   CCKM: TCC=10 TPOT=20 GF=1.0 N0=1 KAP=1.0D+38 VOL=1
   RBM: KX=6.0E+06 FMAX=1   !Analysis of PFGE data

 ! Genome instability and cell transformation
   GIMP: PGA=4.2868541E-05 PGH=0.1 NCG=1000 NCM=1
   NEO: TFS=1.1308766E-05 TFU=2.0E-03 TMAX=42 TSTP=1

!  Generate a synthetic dataset (add white noise to model-predicted responses).  The -n
!  command line option must be used to add noise to the predicted responses.
   NOISE: rerr=0.1 rngs=987654321

!  Parameters that impact on solution accuracy
   SOLVER: DBLV=0 ETOL=1.0E-09 MXSS=999999 HMAX=10

!  Parameters that control the time steps and stopping criteria
   SIMCON: FSDX=1 TSAX=5 TCUT=100 FRDL=1.0D+00 ACUT=1.0D-09

!  Define multiple radiation exposure scenario
    RADX: AD=DD1 ADR=DD2             !Multiple doses and dose rates
    DD1=0, 1, 2, 3, 4, 5, 6, 7, 8, 9, 10 /  !Doses (Gy)
    DD2=0.1, 1.0, 10.0 /                        !Dose rates (Gy/h)