Set the transformation rate for cells with enhanced genomic instability (TFU) NEO: keyword (or sample input files) |
Syntax: Purpose: set the rate at which cells with enhanced (major) genomic instability transition to the neoplastic state Data Type: real Unit: week-1 Default: 0.002 (cells with enhanced genomic instability become neoplastic very quickly) Comments: 0.002 week-1 = 1.19 ´ 10-5 h-1. Calculations are not overly sensitive to the value selected for this parameter. The cell transformation frequency is mainly determined by the PGH, PGA, NCG, and NCM parameters. |
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