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TLK Model Input File #2
Sample Input Files

Tip: Comments are indicated in blue.  For additional details, click on the keywords highlighted in green. Reasonable default values are specified for all model inputs.

/*
TLK Model Sample Input File: Radiosensitivity parameters correspond to an alpha/beta ratio of 8.56 Gy. DSB repair is biphasic (fast repair half-time = 0.25 h, slow repair half-time = 7 hour).  The entire cell population is in a non-dividing (quiescent) state, i.e.,
GF=0.
*/
   MODEL: DRM=TLK CKM=QECK         !Model Specification
   CELL: DNA=5.667D+09 NC=46
   IRAD: DSB=25 FCB=0.2
   CLRP: RHT=HT4R ETA=2.00E-04 PHI=0.001 A0=AAA GAM=0.25
   SLRP: RHT=3  !half-time for SDS repair is 3 minutes

   CCKM: TCC=10 TPOT=20 GF=0.0 N0=1 KAP=1.0D+38 VOL=1
   RBM: KX=6.0E+06 FMAX=1   !Analysis of PFGE data

!  TLK model inputs (simple and complex double strand breaks)
   HT4R = 0.25 7 /      !Half-times for DSB repair
   AAA = 0.95 0.25 /  !Probability DSB is rejoined correctly

!  Parameters that impact on solution accuracy
   SOLVER: DBLV=0 ETOL=1.0E-09 MXSS=999999 HMAX=10

!  Parameters that control the time steps and stopping criteria
   SIMCON: FSDX=1 TSAX=5 TCUT=100 FRDL=1.0D+00 RCUT=1.0D-09

!  Method 3: Dose rate and exposure time
   RADX: ADR=20 DOX=0.2


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Last updated: 10 June, 2011
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