/*
LPL Model Calibration Example: Use this sample file to begin analyzing delayed-plating cell survival data (no repopulation effects; GF=0.0).  If the dataset includes multiple dose rates (low and high dose rates), set the initial DSB yield (DSB parameter) to a value in the range from about 25 to 60 DSB/Gy-cell and adjust the FL, RHT (or LAM), and ETA parameters.  For small datasets, set the DSB parameter to a value in the range from 25 to 60 DSB/Gy-cell, and set RHT to a value in the range from 0.25 to 6 hour.  Then adjust the FL and ETA parameters.  For small datasets, it is very worthwhile to perform a few sensitivity studies to ensure that an optimal fit has been identified.  For example, performs fits with different values for DSB and RHT.
*/
   MODEL: DRM=LPL CKM=QECK         !Model Specification
   CELL: DNA=5.667D+09 NC=46
   IRAD: DSB=25 FL=0.1
   CLRP: RHT=2.0 ETA=2.75E-04 GAM=0.25 A0=0.95
   CCKM: TCC=10 TPOT=20 GF=0.0 N0=1 KAP=1.0D+38 VOL=1
   RBM: KX=6.0E+06 FMAX=1   !Analysis of PFGE data

!  Parameters that impact on solution accuracy
   SOLVER: DBLV=0 ETOL=1.0E-09 MXSS=999999 HMAX=10

!  Parameters that control the time steps and stopping criteria
   SIMCON: FSDX=1 TSAX=12 TCUT=96 FRDL=1.0D+00 RCUT=1.0D-09

   BCONF: MITR=10000 MXFN=100000 SGT=1.0D-04 SST=1.0D-09 FCT=1.0D-09
   MCAT: NPAR=3  !three parameter fit (large datasets)
   AMP1: CID=CLRP PNAM=BMR  PLB=0 PUB=1.0D-02 PIG=1E-04
   AMP2: CID=IRAD  PNAM=FL      PLB=0 PUB=2.0 PIG=0.10
   AMP3: CID=CLRP PNAM=RHT   PLB=0.01 PUB=12.0 PIG=2

/*
  Figure of Merit (FOM) Weight
  1: cell survival data
  2: DSB rejoining data (FAR)
  3: DSB rejoining data (Avg. DSB/cell)
  4: Transformed cells per survivor
  5: Transformed cells per irradiated cell
 */
  FOM: UW=LFWT
  LFWT = 1 0 0 0 0 /