ME 599 - Analysis and Modeling of Cell Mechanics

Lecture

Syllabus

• Syllabus [Updated: 02/10/13]

Homework

• Hwk 1, Due 01/16/13 PDF
• Hwk 2, Due 01/30/13 PDF
• Hwk 3, Due 02/07/13 PDF
• Hwk 4, Due 02/22/13 PDF
• Hwk 5, Due 02/27/13 PDF
• Hwk 6, Due 03/04/13 PDF

Lecture Material (UWNetID secured)

Introductory

• Lecture 1: Intro PDF
• Lecture 2: Building Blocks PDF, Chemistry 101: PDF
• Lecture 3: Nucleus PDF, Other articles: PDF, PDF, PDF
• Lecture 4: Cytoskeleton MBOC
• Lecture 5: Adhesions MBOC
  Additional resources: CSK regulation, Motors, CSK Function, Cell Junctions, PDF, C-C Adhesions, Integrins

Cell Mechanical Analysis

• Lecture 6: Cell Poking PDF, Other articles: PDF, PDF
• Lecture 7: Micropipette Aspiration PDF, Other articles: PDF
• Lecture 8: Atomic Force Microscopy PDF, Other articles: PDF, PDF, PDF
• Lecture 9: Microrheology PDF, Other articles: PDF
• Lecture 10: Magnetic Twisting Cytometry PDF,PDF
• Lecture 11: Optical Tweezers PDF, PDF
Other articles: PDF

Modeling Cell Mechanics

• Lecture 12: Lumped Parameter Models PDF
• Lecture 13: Simple Lipid Systems PDF
• Lecture 14: Tensegrity PDF, Other articles: PDF
• Lecture 15: Foams PDF
• Lecture 16: Polymer Networks PDF
• Lecture 17: Soft Glassy Materials PDF, Other articles: PDF
• Lecture 18: Computational Models PDF, Other articles: PDF, PDF

Cellular Forces

• Lecture 19: Measuring Traction Forces PDF, PDF
• Lecture 20: Continuous Substrata PDF, PDF
• Lecture 21: MEMS tools PDF, PDF

Mechanotransduction

• Lecture 22: Introduction and Examples
• Lecture 23: Whole Cell Studies PDF, PDF, Other articles: PDF
• Lecture 24: Nanoscale Studies PDF, Other articles: PDF, PDF
• Lecture 25: Mechanisms PDF, Other articles: PDF

Lecture Slides

• Lecture 1: PDF
• Lecture 2: PDF
• Lecture 3: PDF
• Lecture 4: PDF
• Lecture 5: PDF
• Lecture 6: PDF
• Lecture 7: PDF
• Lecture 8: PDF
• Lecture 9: PDF
• Lecture 10: PDF
• Lecture 11: PDF
• Lecture 12: PDF
• Lecture 13: PDF
• Lecture 14: PDF
• Lecture 15: PDF
• Lecture 16: PDF
• Lecture 17: PDF
• Lecture 18: PDF
• Lecture 19: PDF
• Lecture 20: PDF
• Lecture 21: PDF
• Lecture 22: PDF
• Lecture 23: PDF
• Lecture 24: PDF
• Lecture 25: PDF

Project

• Project Assignment, Due 03/18/13 PDF