The HTC Matrix

Infectious Days Spent

Author
Affiliation

University of Washington


To understand parasite dispersal by humans, we need the HTC matrix. The human transmitting capacity (HTC) matrix describes the number of fully infectious days spent in each patch from an infection acquired in each patch.


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The HTC matrix can be expressed best as the product of three terms:

HTC Matrix

The HTC matrix is:

\[\left[D_\ell(t, \ell) \right] = \beta(t) \cdot \left[\left< bD_\ell(t, \ell) \right>\right] \cdot \Xi(\ell) \]

and \[\left[D(t)\right] = \int_t^\infty \left[D_\ell(t, \ell) \right] d \ell\]


A diagram of the terms in the HTC matrix (the grey box) and the way those same terms are used in modeling transmission. This follows the notation in [1].

References

1.
Wu SL, Henry JM, Citron DT, Ssebuliba DM, Nsumba JN, C HMS, et al. Spatial dynamics of malaria transmission. PLoS Computational Biology. 2023;19: e1010684. doi:10.1371/journal.pcbi.1010684