• Journals

    1. [J62] Keller SB, Lai TY, De Koninck L, Averkiou MA. "Investigation of the phase of nonlinear echoes from microbubbles during amplitude modulation". IEEE Trans Ultrason Ferroelectr Freq Control. 2022 Jan 24;PP. doi: 10.1109/TUFFC.2022.3143810. PubMed PMID: 35073259.
    2. [J61] Keller SB, Averkiou MA. "The Role of Ultrasound in Modulating Interstitial Fluid Pressure in Solid Tumors for Improved Drug Delivery". Bioconjug Chem. 2021 Sep 12. doi: 10.1021/acs.bioconjchem.1c00422. PubMed PMID: 34514776.
    3. [J60] Keller SB, Wang YN, Totten S, Yeung RS, Averkiou MA. "Safety of Image-Guided Treatment of the Liver with Ultrasound and Microbubbles in an in Vivo Porcine Model". Ultrasound Med Biol. 2021 Nov;47(11):3211-3220. doi: 10.1016/j.ultrasmedbio.2021.07.003. PubMed PMID: 34362584.
    4. [J59] Clark A, Bonilla S, Suo D, Shapira Y, Averkiou M. "Microbubble-Enhanced Heating: Exploring the Effect of Microbubble Concentration and Pressure Amplitude on High-Intensity Focused Ultrasound Treatments". Ultrasound Med Biol. 2021 Aug;47(8):2296-2309. doi: 10.1016/j.ultrasmedbio.2021.03.035. PubMed PMID: 33985825.
    5. [J58] Lai TY, Averkiou MA. "Linear Signal Cancellation of Nonlinear Pulsing Schemes in a Verasonics Research Scanner". IEEE Trans Ultrason Ferroelectr Freq Control. 2021 May;68(5):1721-1728. doi: 10.1109/TUFFC.2021.3050481. PubMed PMID: 33428569.
    6. [J57] Keller SB, Sheeran PS, Averkiou MA. "Cavitation Therapy Monitoring of Commercial Microbubbles With a Clinical Scanner". IEEE Trans Ultrason Ferroelectr Freq Control. 2021 Apr;68(4):1144-1154. doi: 10.1109/TUFFC.2020.3034532. PubMed PMID: 33112743.
    7. [J56] Keller SB, Suo D, Wang YN, Kenerson H, Yeung RS, Averkiou MA. "Image-Guided Treatment of Primary Liver Cancer in Mice Leads to Vascular Disruption and Increased Drug Penetration". Front Pharmacol. 2020 Sep 30;11:584344. doi: 10.3389/fphar.2020.584344. PubMed PMID: 33101038.
    8. [J55] Averkiou MA, Juang EK, Gallagher MK, Cuevas MA, Wilson SR, Barr RG, Carson PL. "Evaluation of the Reproducibility of Bolus Transit Quantification With Contrast-Enhanced Ultrasound Across Multiple Scanners and Analysis Software Packages-A Quantitative Imaging Biomarker Alliance Study". Invest Radiol. 2020 Oct;55(10):643-656. doi: 10.1097/RLI.0000000000000702. PubMed PMID: 32898356.
    9. [J54] Malone CD, Fetzer DT, Monsky WL, Itani M, Mellnick VM, Velez PA, Middleton WD, Averkiou MA, Ramaswamy RS. "Contrast-enhanced US for the Interventional Radiologist: Current and Emerging Applications". Radiographics. 2020 Mar-Apr;40(2):562-588. doi: 10.1148/rg.2020190183. PubMed PMID: 32125955.
    10. [J53] Averkiou MA, Bruce MF, Powers JE, Sheeran PS, Burns PN. "Imaging Methods for Ultrasound Contrast Agents". Ultrasound Med Biol. 2020 Mar;46(3):498-517. doi: 10.1016/j.ultrasmedbio.2019.11.004. PubMed PMID: 31813583.
    11. [J52] Butler M, Perperidis A, Zahra JLM, Silva N, Averkiou M, Duncan WC, McNeilly A, Sboros V. "Differentiation of vascular characteristics using contrast enhanced ultrasound imaging". Ultrasound Med Biol. 2019 Sep;45(9):2444-2455. doi: 10.1016/j.ultrasmedbio.2019.05.015. PubMed PMID: 31208880.
    12. [J51] Kanoulas E, Butler M, Rowley CL, Voulgaridou V, Diamantis K, Fox K, Duncan WC, McNeilly AS, Averkiou M, Wijkstra H, Mischi M, Wilson RS, Lu W, Sboros V. "SuperResolution Contrast Enhanced Ultrasound Methodology for the Identification of in-Vivo Vascular Dynamics in 2D". Invest Radiol. 2019 Aug;54(8):500-516. doi: 10.1097/RLI.0000000000000565. PubMed PMID: 31058661.
    13. [J50] Lai TY, Bruce M, Averkiou M. "Modeling of the Acoustic Field Produced by Diagnostic Ultrasound Arrays in Plane and Diverging Wave Modes". IEEE Trans Ultrason Ferroelectr Freq Control. 2019 Apr 2. doi: 10.1109/TUFFC.2019.2908831. PubMed PMID: 30951464.
    14. [J49] Monsky W, Keravnou C, Averkiou M. "Contrast-enhanced ultrasound to ultrasound fusion during microwave ablation: feasibility study in a perfused porcine liver model". J Ultrasound. 2019 Feb 27. doi: 10.1007/s40477-019-00366-5. PubMed PMID: 30811016.
    15. [J48] Keller S, Bruce M, Averkiou MA. "Ultrasound Imaging of Microbubble Activity during Sonoporation Pulse Sequences". Ultrasound Med Biol. 2019 Mar;45(3):833-845. doi: 10.1016/j.ultrasmedbio.2018.11.011. PubMed PMID: 30638695.
    16. [J47] Juang EK, De Cock I, Keravnou C, Gallagher MK, Keller SB, Zheng Y, Averkiou M. "Engineered 3D microvascular networks for the study of ultrasound-microbubble-mediated drug delivery". Langmuir. 2018 Dec 12. doi: 10.1021/acs.langmuir.8b03288. PubMed PMID: 30540481.
    17. [J46] Dietrich CF, Averkiou M, Nielsen MB, Barr RG, Burns PN, Calliada F, Cantisani V, Choi B, Chammas MC, Clevert DA, Claudon M, Correas JM, Cui XW, Cosgrove D, D'Onofrio M, Dong Y, Eisenbrey J, Fontanilla T, Gilja OH, Ignee A, Jenssen C, Kono Y, Kudo M, Lassau N, Lyshchik A, Franca Meloni M, Moriyasu F, Nolsøe C, Piscaglia F, Radzina M, Saftoiu A, Sidhu PS, Sporea I, Schreiber-Dietrich D, Sirlin CB, Stanczak M, Weskott HP, Wilson SR, Willmann JK, Kim TK, Jang HJ, Vezeridis A, Westerway S. "How to perform Contrast-Enhanced Ultrasound (CEUS)". Ultrasound Int Open. 2018 Jan;4(1):E2-E15. doi: 10.1055/s-0043-123931. PubMed PMID: 29423461.
    18. [J45] Keravnou CP, De Cock I, Lentacker I, Izamis ML, Averkiou MA. "Microvascular Injury and Perfusion Changes Induced by Ultrasound and Microbubbles in a Machine-Perfused Pig Liver". Ultrasound Med Biol. Vol. 42, No. 11, pp. 2676–2686, November 2016. doi: 10.1016/j.ultrasmedbio.2016.06.025. PubMed PMID: 27554068.
    19. [J44] Averkiou MA, Keravnou CP, Izamis ML, Leen E. "Evaluation of Perfusion Quantification Methods with Ultrasound Contrast Agents in a Machine-Perfused Pig Liver". Ultraschall Med. 2016 May 3. [Epub ahead of print] PubMed PMID: 27139375.
    20. [J43] Christofides D, Leen E, Averkiou M. "Evaluation of the accuracy of liver lesion DCEUS quantification with respiratory gating". IEEE Trans Med Imaging. 2015 Oct 7. [Epub ahead of print] PubMed PMID: 26452276.
    21. [J42] Keravnou CP, Izamis ML, Averkiou MA. "Method for Estimating the Acoustic Pressure in Tissues Using Low-Amplitude Measurements in Water". Ultrasound Med Biol. 2015 Nov;41(11):3001-12. doi: 10.1016/j.ultrasmedbio.2015.07.005. Epub 2015 Aug 28. PubMed PMID: 26320668.
    22. [J41] Christofides D, Leen EL, Averkiou MA. "Improvement of the accuracy of liver lesion DCEUS quantification with the use of automatic respiratory gating". Eur Radiol. 2015 Apr 30. [Epub ahead of print] PubMed PMID: 25925359.
    23. [J40] Keravnou CP, Mannaris C, Averkiou MA. "Accurate measurement of microbubble response to ultrasound with a diagnostic ultrasound scanner". IEEE Trans Ultrason Ferroelectr Freq Control. 2015 Jan;62(1):176-84. doi: 10.1109/TUFFC.2014.006664. PubMed PMID: 25585401.
    24. [J39] Perperidis A, Thomas D, Averkiou M, Duncan C, McNeilly A, Butler M, Sboros V. "Automatic dissociation between microvasculature and larger vessels for ultrasound contrast imaging". Conf Proc IEEE Eng Med Biol Soc. 2014;2014:5076-9. doi: 10.1109/EMBC.2014.6944766. PubMed PMID: 25571134.
    25. [J38] Powers J, Averkiou M. "Principles of cerebral ultrasound contrast imaging". Front Neurol Neurosci. 2015;36:1-10. doi: 10.1159/000366222. Epub 2014 Dec 22. Review. PubMed PMID: 25531658.
    26. [J37] Izamis ML, Efstathiades A, Keravnou C, Leen EL, Averkiou MA. "Dynamic contrast-enhanced ultrasound of slaughterhouse porcine livers in machine perfusion". Ultrasound Med Biol. 2014 Sep;40(9):2217-30. doi: 10.1016/j.ultrasmedbio.2014.03.031. Epub 2014 Jul 9. PubMed PMID: 25023101.
    27. [J36] Keravnou CP, Averkiou MA. "Harmonic generation with a dual frequency pulse". J Acoust Soc Am. 2014 May;135(5):2545-52. doi: 10.1121/1.4871356. PubMed PMID: 24815238.
    28. [J35] Izamis ML, Efstathiades A, Keravnou C, Georgiadou S, Martins PN, Averkiou MA. "Effects of air embolism size and location on porcine hepatic microcirculation in machine perfusion". Liver Transpl. 2014 May;20(5):601-11. doi: 10.1002/lt.23838. PubMed PMID: 24478135.
    29. [J34] Christofides D, Leen E, Averkiou M. "Automatic respiratory gating for contrast ultrasound evaluation of liver lesions". IEEE Trans Ultrason Ferroelectr Freq Control. 2014 Jan;61(1):25-32. doi: 10.1109/TUFFC.2014.6689773. PubMed PMID: 24402893.
    30. [J33] Mannaris C, Efthymiou E, Meyre ME, Averkiou MA. "In vitro localized release of thermosensitive liposomes with ultrasound-induced hyperthermia". Ultrasound Med Biol. 2013 Nov;39(11):2011-20. doi: 10.1016/j.ultrasmedbio.2013.06.001. Epub 2013 Aug 22. PubMed PMID: 23972488.
    31. [J32] Escoffre JM, Mannaris C, Geers B, Novell A, Lentacker I, Averkiou M, Bouakaz A. "Doxorubicin liposome-loaded microbubbles for contrast imaging and ultrasound-triggered drug delivery". IEEE Trans Ultrason Ferroelectr Freq Control. 2013 Jan;60(1):78-87. doi: 10.1109/TUFFC.2013.2539. PubMed PMID: 23287915.
    32. [J31] Dietrich CF, Averkiou MA, Correas JM, Lassau N, Leen E, Piscaglia F. "An EFSUMB introduction into Dynamic Contrast-Enhanced Ultrasound (DCE-US) for quantification of tumour perfusion". Ultraschall Med. 2012 Aug;33(4):344-51. Epub 2012 Jul 27. PubMed PMID: 22843433.
    33. [J30] Leen E, Averkiou M, Arditi M, Burns P, Bokor D, Gauthier T, Kono Y, Lucidarme O. "Dynamic contrast enhanced ultrasound assessment of the vascular effects of novel therapeutics in early stage trials". Eur Radiol. 2012 Jul;22(7):1442-50. doi: 10.1007/s00330-011-2373-2. PubMed PMID: 22302501.
    34. [J29] Mannaris C, Averkiou MA. "Investigation of microbubble response to long pulses used in ultrasound-enhanced drug delivery". Ultrasound Med Biol. 2012 Apr;38(4):681-91. doi: 10.1016/j.ultrasmedbio.2011.12.018. Epub 2012 Feb 15. PubMed PMID: 22341047.
    35. [J28] Gauthier TP, Averkiou MA, Leen EL. "Perfusion quantification using dynamic contrast-enhanced ultrasound: the impact of dynamic range and gain on time-intensity curves". Ultrasonics. 2011 Jan;51(1):102-6. doi: 10.1016/j.ultras.2010.06.004. Epub 2010 Jun 25. PubMed PMID: 20643467.
    36. [J27] Thapar A, Shalhoub J, Averkiou M, Mannaris C, Davies AH, Leen EL. "Dose-dependent artifact in the far wall of the carotid artery at dynamic contrast-enhanced US". Radiology. 2012 Feb;262(2):672-9. doi: 10.1148/radiol.11110968. Epub 2011 Dec 9. PubMed PMID: 22156991.
    37. [J26] Sboros V, Averkiou M, Lampaskis M, Thomas DH, Silva N, Strouthos C, Docherty J, McNeilly AS. "Imaging of the ovine corpus luteum microcirculation with contrast ultrasound". Ultrasound Med Biol. 2011 Jan;37(1):59-68. doi: 10.1016/j.ultrasmedbio.2010.10.013. PubMed PMID: 21144958.
    38. [J25] Strouthos C, Lampaskis M, Sboros V, McNeilly A, Averkiou M. "Indicator dilution models for the quantification of microvascular blood flow with bolus administration of ultrasound contrast agents". IEEE Trans Ultrason Ferroelectr Freq Control. 2010 Jun;57(6):1296-310. doi: 10.1109/TUFFC.2010.1550. Review. PubMed PMID: 20529706.
    39. [J24] Lampaskis M, Averkiou M. "Investigation of the relationship of nonlinear backscattered ultrasound intensity with microbubble concentration at low MI". Ultrasound Med Biol. 2010 Feb;36(2):306-12. doi: 10.1016/j.ultrasmedbio.2009.09.011. Epub 2010 Jan 4. PubMed PMID: 20045592.
    40. [J23] Averkiou M, Lampaskis M, Kyriakopoulou K, Skarlos D, Klouvas G, Strouthos C, Leen E. "Quantification of tumor microvascularity with respiratory gated contrast enhanced ultrasound for monitoring therapy". Ultrasound Med Biol. 2010 Jan;36(1):68-77. doi: 10.1016/j.ultrasmedbio.2009.07.005. Epub . PubMed PMID: 19900749.
    41. [J22] Powers J, Averkiou M, Bruce M. "Principles of cerebral ultrasound contrast imaging". Cerebrovasc Dis. 2009;27 Suppl 2:14-24.
    42. [J21] Leen E, Kumar S, Khan SA, Low G, Ong KO, Tait P, Averkiou M. "Contrast-enhanced 3D ultrasound in the radiofrequency ablation of liver tumors". World J Gastroenterol. 2009 Jan 21;15(3):289-99.
    43. [J20] Fowlkes J.B., Abramowicz J.S., Church C.C., Holland C.K., Miller D.L., O'Brien Jr. W.D., Sanghvi N.T., Stratmeyer M.E., Zachary J.F., Deng C.X., Harris G.R., Herman B.A., Hynynen K.H., Merritt C.R.B., Thomenius K.E., Bailey M.R., Carson P.L., Carstensen E.L., Frizzell L.A., Nyborg W.L., Barnett S.B., Duck F.A., Edmonds P.D., Ziskin M.C., Abbott J.G., Dalecki D., Dunn F., Greenleaf J.F., Salvesen K.A., Siddiqi T.A., Averkiou M.A., Brayman A.A., Everbach E.C., Wible Jr. J.H., Wu J. & Simpson D.G. "American Institute of Ultrasound in Medicine consensus report on potential bioeffects of diagnostic ultrasound: Executive summary", Journal of Ultrasound in Medicine, 27(4), pp. 503-515, 2008.
    44. [J19] Miller DL, Averkiou MA, Brayman AA, Everbach EC, Holland CK, Wible JH Jr, Wu J. "Bioeffects considerations for diagnostic ultrasound contrast agents". J Ultrasound Med. 2008 Apr;27(4):611-32; quiz 633-6. Review.
    45. [J18] Averkiou M. and Powers J. "Ultrasound contrast media in the characterization of soft tissue lesions: ongoing research". MEDICAMUNDI, 51/2+3, 80-94, 2007.
    46. [J17] Khokhlova V. A., Ponomarev A. E., Averkiou M. A., and Crum L. A. "Nonlinear pulsed ultrasound beams radiated by rectangular focused diagnostic transducers". Ac. Physics 52(4), 560- 570, 2006.
    47. [J16] Guan J., Matula T. J., and Averkiou M. "Imaging the destruction of individual ultrasound contrast microbubbles with diagnostic ultrasound". Acoustic Research Letters Online 5, pp. 165-169, 2004.
    48. [J15] Bruce M, Averkiou M, Tiemann K, Lohmaier S, Powers J, Beach K. "Vascular flow and perfusion imaging with ultrasound contrast agents". Ultrasound Med Biol. 2004 Jun;30(6):735-43.
    49. [J14] Averkiou M, Powers J, Skyba D, Bruce M, Jensen S. "Ultrasound contrast imaging research". Ultrasound Q. 2003 Mar;19(1):27-37.
    50. [J13] Sboros V, Moran CM, Anderson T, Gatzoulis L, Criton A, Averkiou M, Pye SD, McDicken WN. "An in vitro system for the study of ultrasound contrast agents using a commercial imaging system". Phys Med Biol. 2001 Dec;46(12):3301-21.
    51. [J12] Simpson DH, Burns PN, Averkiou MA. "Techniques for perfusion imaging with microbubble contrast agents". IEEE Trans Ultrason Ferroelectr Freq Control. 2001 Nov;48(6):1483-94.
    52. [J11] Averkiou MA. "Tissue harmonic ultrasonic imaging". Comptes Rendus de l'Academie des Sciences - Series IV: Physics, Astrophysics. 2001;2(8):1139-51.
    53. [J10] Kashcheeva SS, Sapozhnikov OA, Khokhlova VA, Averkiou MA, Crum LA. "Nonlinear distortion and attenuation of intense acoustic waves in lossy media obeying a frequency power law". Ac. Physics. 2000;46(2):170-177.
    54. [J9] Makin IR, Averkiou MA, Hamilton MF. "Second-harmonic generation in a sound beam reflected and transmitted at a curved interface". J Acoust Soc Am. 2000 Oct;108(4):1505-13.
    55. [J8] Burns PN, Hope Simpson D, Averkiou MA. "Nonlinear imaging". Ultrasound Med Biol. 2000 May;26 Suppl 1:S19-22.
    56. [J7] Sboros V, Moran CM, Anderson T, Criton A, Averkiou M, McDicken WN. "Assessment of the properties of ultrasound contrast agents using a commercial scanner: Preliminary results". Ultrasound in Medicine and Biology. 2000;26(SUPPL. 2).
    57. [J6] Averkiou MA, Cleveland RO. " Modeling of an electrohydraulic lithotripter with the KZK equation". J Acoust Soc Am. 1999 Jul;106(1):102-12.
    58. [J5] Becher H, Tiemann K, Schlosser T, Pohl C, Nanda NC, Averkiou MA, Powers J, Lüderitz B. "Improvement in Endocardial Border Delineation Using Tissue Harmonic Imaging". Echocardiography. 1998 Jul;15(5):511-518.
    59. [J4] Morgan KE, Averkiou M, Ferrara K. "The effect of the phase of transmission on contrast agent echoes". IEEE Trans Ultrason Ferroelectr Freq Control. 1998;45(4):872-5.
    60. [J3] Averkiou MA, Hamilton MF. "Nonlinear distortion of short pulses radiated by plane and focused circular pistons". J Acoust Soc Am. 1997 Nov;102(5 Pt 1):2539-48.
    61. [J2] Averkiou MA, Hamilton MF. "Measurements of harmonic generation in a focused finite-amplitude sound beam". J Acoust Soc Am. 1995 Dec;98(6):3439-42.
    62. [J1] Averkiou MA, Lee YS, and Hamilton MF. "Self demodulation of amplitude and frequency modulated pulses in a viscous fluid". J. Acoust. Soc. Am. 1993; 94, 2876-2883.
  • Book Chapters

    1. [B7] J. Eisenbrey, M. Averkiou, F. Frosberg, "Physical Principles of CEUS," in Specialty Imaging: Fundamentals of CEUS, 1st Edition, A. Lyshchik editor, Elsevier, ISBN-10: 0323625649, 2019
    2. [B6] M. Averkiou, F. Frosberg, J. Eisenbrey, "Safety and Biological Effect of Microbubble-based Contrast Agents," in Specialty Imaging: Fundamentals of CEUS, 1st Edition, A. Lyshchik editor, Elsevier, ISBN-10: 0323625649, 2019.
    3. [B5] M. Mischi, N. Rognin, M. A. Averkiou, "Ultrasound Imaging Modalities," in Comprehensive Biomedical Physics, Elsevier, MEPH: 00217, 2013.
    4. [B4] M. A. Averkiou, C. Mannaris, A. Nicolaides, "Vascular Ultrasound Imaging with Contrast Agents: Carotid Plaque Neovascularization and the Hyperplastic Vasa Vasorum Network," in A. Nicolaides et al. (eds.), Ultrasound and Carotid Bifurcation Atherosclerosis, pp. 121-136, Springer-Verlag London Limited, 2012.
    5. [B3] G. A. Schwartz and M. A. Averkiou, "Future Directions - New Developments in Ultrasound," in Imaging in Oncological Urology, J. de la Rosette, M. Harisinghani, M. Manyak, and H. Wijkstra, eds, Springer-Verlag, London, 2008.
    6. [B2] M. Averkiou, "Tissue harmonic ultrasonic imaging," in Optical and acoustical imaging of biological media, C. R. Acad. Sci. Paris, Applied Physics(Biophysiscs), t. 2, Serie IV, Elsevier, Paris, pp.1139-1151, 2001.
    7. [B1] M. A. Averkiou and L. A. Crum, "Cavitation: Its role in stone comminution and renal injury," in Topics in clinical Urology: New Developments in the management of urolithiasis, J. Lingeman & G. M. Preminger, eds, Igaku-Shoin Medical Publishers, Inc., New York, pp.21-40, 1995.