• BIOEN 449/549 Therapeutic and Diagnostic Ultrasound

    This is a comprehensive course on ultrasound as used in biomedical applications for engineering and science students. The course covers both diagnostic and therapeutic applications of ultrasound. An introductory level knowledge on ultrasound imaging is preferred but not necessary. The physical principles of ultrasound necessary for explaining diagnostic ultrasound are covered first. These include wave propagation, reflection and transmission of sound at interfaces, scattering, attenuation, acoustic impedance, signals, and Fourier analysis. Array beam forming and image formation are covered in detail. The main imaging modes of clinical diagnostic ultrasound systems are presented and explained in lectures, homework problems and hands on laboratory exercises. Topics include nonlinear tissue imaging and contrast agents with special emphasis on nonlinear pulsing schemes as well as 3D imaging and elastography. Therapeutic applications of ultrasound are covered such as tissue ablation with High Intensity Focused Ultrasound (HIFU). The heat transfer process is explained with theoretical models like the Bioheat equation. Mechanical effects of ultrasound such as cavitation in lithotripsy and histotripsy are covered. Ultrasound-mediated drug delivery approaches which rely on both thermal and mechanical effects of ultrasound are covered.

    Instructor: Mike Averkiou

    Credits: 4

  • BIOE 447/547 Fundamentals of Magnetic Resonance and Ultrasound Imaging

    This course provides graduate level engineering and science students with fundamentals of MRI and Ultrasound for creating advancements in medical imaging. The course spends the first half covering topics in MRI, specifically the physics, design of pulse sequences, and image formation. The second half of the course will cover first the physical principles of sound waves and ultrasound. Topics include the wave equation, acoustic impedance, reflection and transmission of sound, refraction, basic signal processing, sound beams, transducers, arrays, beamforming, ultrasound attenuation, and scattering. The fundamentals of ultrasound image formation and current equipment technology are presented next. Ultrasound imaging modes covered: M-mode, B-mode, Doppler and color flow, Harmonic Imaging, 3D imaging, ultrasound contrast imaging techniques.

    Instructor: Mike Averkiou and Chun Yuan

    Credits: 4

  • BIOE 532 Bioengineering Professional Series III: Professional Skills Development

    Key areas of professional development related to the bioengineering field, including oral communication, management, networking, and interviewing.

    Instructor: Mike Averkiou

    Credits: 1