In this work, we used a combination of sterolomics, lipidomics, and transcriptomics to investigate the consequences of sterol and lipid homeostasis in neonatal brains after in utero exposure. Check out the paper here. Update on 09/10/19, the paper was highlighted in Tox Spotlight and selected as a cover art of the issue!
Kelly, Dylan, Amy, and Josi had fun presenting their work at the ASMS meeting last week (June 02-06), including two oral presentations and two poster presentations! Well done, everyone! Proud of you!
Kelly was selected as one of nine finalists for the Postdoc Mentoring Award from a large pool of nominations from 11 schools and colleges! This is a fitting recognition for her dedication in mentoring graduate and undergraduate students in the lab, which we all greatly appreciate! Congratulations, Kelly! Well deserved! Check out the news here.
Recently, we have a few undergraduate students joining the lab: Jonathan Luong in January and Pakteema Tong and Qingyu Guo in April! They are all majoring in Biochemistry at the UW and expect to graduate in 2020! Welcome to the team!
Nice work, Kelly! Check out the paper here.
Congrats, Dylan! Well done!
This study led by Profs. Kelly and Himmelfarb reported assessment of the nephrotoxicity of the antibiotic polymyxin using human kidney-on-a-chip. We carried out the analysis of sterols for this work. Congrats to Cecilia, Kelly, and Josi! Check out the paper here.
This is a review on the role of oxysterols in retinal degeneration of a rat model of Smith-Lemli-Opitz syndrome. Check out the paper here.
This work reported cilia-associated oxysterols can activate Hedgehog signaling through Smoothened and inhibition of the formation of such oxysterols can impede Hedgehog pathway activation. This is a multi-institutional collaboration led by David Raleigh and Jeremy Reiter at UCSF. Good job by Kelly on the oxysterol analysis in this work! Check out the paper here and the Cover Art of the issue illustrating findings in this paper.
Check out the paper here. Congrats, Josi and Kelly!
