Our collaborative paper with the Wang Lab on the transport of benzalkonium chlorides (BACs) by OCTs and hMATEs was published in Drug Metabolism and Disposition!

Congratulations to Dr. Vieira in the Joanne Wang’s Lab in the Department of Pharmaceutics and Dr. Ryan Seguin in our lab! We found that short-chain (C8 and C10) BACs are substrates of OCTs and hMATES while all BACs are inhibitors of these transporters using metformin as the probe substrate. Check out the paper here.