Congratulations to Dr. Vieira in the Joanne Wang’s Lab in the Department of Pharmaceutics and Dr. Ryan Seguin in our lab! We found that short-chain (C8 and C10) BACs are substrates of OCTs and hMATES while all BACs are inhibitors of these transporters using metformin as the probe substrate. Check out the paper here.
![](http://faculty.washington.edu/libinxu/wordpress/wp-content/uploads/2024/04/BAC-transport-1024x300.jpg)