Congratulations to Quynh on a successful defense of her PhD thesis titled “Lipid Peroxidation Mechanisms and Their Contribution to Ferroptosis”! PhD #3 from the lab!
Our paper on the role of 7-dehydrocholesterol-derived oxysterols in SLOS neurogenesis published in eLife!
Congratulations to Dr. Hideaki Tomita and coauthors! In this work, we investigated the impact of defective cholesterol biosynthesis at the step of DHCR7 on embryonic neurogenesis, the underlying mechanisms, and ways to rescue the neurogenesis phenotypes. Check out the paper here!
Congratulations to Ryan Nguyen on receiving the Environmental Pathology/Toxicology Fellowship!
Ryan’s project will focus on characterizing the exposome of ToxCast chemicals using ion mobility-mass spectrometry! Congrats, Ryan! Way to go! Check out the NIEHS-funded EPT training program here.
We welcome Noelle, Linxi, and Ryan N. to our lab!
We are excited to welcome three Med Chem graduate students to join our lab this year: Noelle Reimers, Linxi Zhu, and Ryan Nguyen! Noelle will work on lipid peroxidation and ferroptosis, Linxi will work on metabolism of benzalkonium chloride, and Ryan will work on the impact of metabolism on human exposome. Can’t wait to see what you will accomplish!
Rutan’s first-author paper reporting and characterizing a clinical dalbavancin-resistant MRSA strain was accepted to Clinical Infectious Disease!
This is a collaboration with Prof. Brian Werth in the Department of Pharmacy and Dr. Hari Polenakovik at Wright State U School of Medicine! Check out the paper here. Congrats, Rutan!
Congratulations to Ryan on receiving First Place Award in Postdoctoral Poster Competition at ASPET!
In the division for Drug Metabolism and Disposition. Check out the award list here. Good job, Ryan!
Congratulations to Amy on her first-author paper on the lipidomics of developing WT and SLOS mouse brains!
Well done, Amy! Check out this work here!
We are awarded a pilot grant from UW EDGE Center to study the impact of benzalkonium chloride on gut microbiome!
We are excited to venture into this exciting research direction with our co-investigator, Dr. Julia Cui at DEOHS and are grateful for the support from the UW EDGE Center Pilot Project Program funded by the NIEHS (P30ES007033). Congratulations to Vanessa, Ryan, and the rest of Team QACs!
We are awarded an R01 to study the metabolism, transport, and toxicity of benzalkonium chlorides from NIEHS!
In this project, we aim to define the pathways of metabolism and transport of the widely used disinfectant, benzalkonium chlorides (BACs), and elucidate interactions between the metabolism and transport capacity and kidney toxicity of BACs in vitro and in humans. This project involves collaboration with Prof. Allan Rettie at Med Chem and Profs. Joanne Wang, Ed Kelly, and Yvonne Lin at UW Pharmaceutics. Congrats to the team @Ryan @Vanessa @Marie!
Congrats to Rutan on his first author paper with the Werth Lab!
By correlating lipid profile, MIC and time-kill profiles, we found that “Synergy Between Beta-Lactams and Lipo-, Glyco-, and Lipoglycopeptides, Is Independent of the Seesaw Effect in Methicillin-Resistant Staphylococcus aureus“. Congrats, Rutan!