This paper covers a lot of cool studies in drug and drug metabolites characterization, including some of ours. Check out the paper here.
Benzalkonium chlorides are a major component of widely used disfectants, such as Lysol and Clorox, which has seen greatly increased usage during COVID-19. This work shed light on the potential neurotoxicity of these compounds. Check out the paper here.
This work identified Hedgehog signaling negatively regulate DHCR7 and positively regulate CYP7A1, leading to increases in Smo-activating oxysterol levels! Check out this paper here.
This improved radical clock allows the measurements of some new lipid peroxidation rate constants, particularly those containing highly conjugated systems, such as vitamin A, vitamin D3, and conjugated polyunsaturated fatty acids. With this “clock”, the full kinetic picture of lipid peroxidation can be elucidated now. Congrats to Qunyh, Ryan, Rutan, and our former members David Lee and Andrew Dinh! Check out the paper here.
This all-in-one package, LiPydomics, contains a large experimental and predicted database of CCS and HILIC retention time, allows data processing, lipid identification with multi-dimensional data, statistical analysis, plotting, and comes with a text-based interface. The database is also available at CCSbase.net. Check out the paper here.
Effective 07/01/2020! Thanks to all the the past and current members who made this possible and the support from my colleagues in the Department of Medicinal Chemistry and the School of Pharmacy throughout the past five years!
This is a collaboration with Prof. Brian Wilkinson at Illinois State and Prof. Francis Alonzo at Loyola U Chicago. Congrats to former postdoc, Dr. Kelly Hines! The paper was selected as the Cover Image of the issue.
The Institute of Translational Health Sciences TL1 is an NIH-funded training grant that will allow Amy to undergo additional trainings in translational science!
The Magnuson Scholarship recognizes graduate students in the UW Health Sciences for their excellent academic performance and outstanding potential for research in the health sciences! Check out the news coverage here and here.
Congratulations, Amy, for these well-deserving achievements!
Check out the paper here at Analytical Chemistry. Access the database and prediction model at https://ccsbase.net/. Congratulations, Dylan and Jang Ho!
Congratulations, Dylan! He will present his work on studying drug metabolism using ion mobility-mass spectrometry and machine learning. Check out his recent work here.
