This improved radical clock allows the measurements of some new lipid peroxidation rate constants, particularly those containing highly conjugated systems, such as vitamin A, vitamin D3, and conjugated polyunsaturated fatty acids. With this “clock”, the full kinetic picture of lipid peroxidation can be elucidated now. Congrats to Qunyh, Ryan, Rutan, and our former members David Lee and Andrew Dinh! Check out the paper here.
This all-in-one package, LiPydomics, contains a large experimental and predicted database of CCS and HILIC retention time, allows data processing, lipid identification with multi-dimensional data, statistical analysis, plotting, and comes with a text-based interface. The database is also available at CCSbase.net. Check out the paper here.
Effective 07/01/2020! Thanks to all the the past and current members who made this possible and the support from my colleagues in the Department of Medicinal Chemistry and the School of Pharmacy throughout the past five years!
This is a collaboration with Prof. Brian Wilkinson at Illinois State and Prof. Francis Alonzo at Loyola U Chicago. Congrats to former postdoc, Dr. Kelly Hines! The paper was selected as the Cover Image of the issue.
The Institute of Translational Health Sciences TL1 is an NIH-funded training grant that will allow Amy to undergo additional trainings in translational science!
The Magnuson Scholarship recognizes graduate students in the UW Health Sciences for their excellent academic performance and outstanding potential for research in the health sciences! Check out the news coverage here and here.
Congratulations, Amy, for these well-deserving achievements!
Check out the paper here at Analytical Chemistry. Access the database and prediction model at https://ccsbase.net/. Congratulations, Dylan and Jang Ho!
Congratulations, Dylan! He will present his work on studying drug metabolism using ion mobility-mass spectrometry and machine learning. Check out his recent work here.
This is a collaborative work with the Werth lab at the Department of Pharmacy and Salipante Lab at Laboratory Medicine! Check out the paper at Journal of Antimicrobial Chemotherapy: Occurrence of cross-resistance and β-lactam seesaw effect in glycopeptide-, lipopeptide- and lipoglycopeptide-resistant MRSA correlates with membrane phosphatidylglycerol levels.
Our lab and Ed Kelly Lab receive a Faculty Innovation Award from UW School of Pharmacy to study the toxicogenetics of benzalkonium chlorides using “liver-kidney-on-chips”! Check out the announcement here!
This award will help us look at the role of oxysterol detoxification by glutathione S-transferases in Smith-Lenti-Opitz syndrome, a rare disease, but not so rare in terms of carrier frequency (1 in 30)!