This is a landmark review on the widely used antimicrobials, quaternary ammonium compounds (QACs)! Check it out here.
Ryan Seguin and Libin co-authored review on QACs published in Environmental Science and Technology!
Quynh’s paper on lipid peroxidation mechanisms and ferroptosis published in JACS Au!
This paper aims to understand the chemical and biochemical mechanisms underlying the different potency of conjugated and nonconjugated polyunsaturated fatty acids in inducing ferroptosis. Check out the paper here.
Quynh successfully defended her thesis!
Congratulations to Quynh on a successful defense of her PhD thesis titled “Lipid Peroxidation Mechanisms and Their Contribution to Ferroptosis”! PhD #3 from the lab!
Our paper on the role of 7-dehydrocholesterol-derived oxysterols in SLOS neurogenesis published in eLife!
Congratulations to Dr. Hideaki Tomita and coauthors! In this work, we investigated the impact of defective cholesterol biosynthesis at the step of DHCR7 on embryonic neurogenesis, the underlying mechanisms, and ways to rescue the neurogenesis phenotypes. Check out the paper here!
Congratulations to Ryan Nguyen on receiving the Environmental Pathology/Toxicology Fellowship!
Ryan’s project will focus on characterizing the exposome of ToxCast chemicals using ion mobility-mass spectrometry! Congrats, Ryan! Way to go! Check out the NIEHS-funded EPT training program here.
We welcome Noelle, Linxi, and Ryan N. to our lab!
We are excited to welcome three Med Chem graduate students to join our lab this year: Noelle Reimers, Linxi Zhu, and Ryan Nguyen! Noelle will work on lipid peroxidation and ferroptosis, Linxi will work on metabolism of benzalkonium chloride, and Ryan will work on the impact of metabolism on human exposome. Can’t wait to see what you will accomplish!
Rutan’s first-author paper reporting and characterizing a clinical dalbavancin-resistant MRSA strain was accepted to Clinical Infectious Disease!
This is a collaboration with Prof. Brian Werth in the Department of Pharmacy and Dr. Hari Polenakovik at Wright State U School of Medicine! Check out the paper here. Congrats, Rutan!
Congratulations to Ryan on receiving First Place Award in Postdoctoral Poster Competition at ASPET!
In the division for Drug Metabolism and Disposition. Check out the award list here. Good job, Ryan!
Congratulations to Amy on her first-author paper on the lipidomics of developing WT and SLOS mouse brains!
Well done, Amy! Check out this work here!
We are awarded a pilot grant from UW EDGE Center to study the impact of benzalkonium chloride on gut microbiome!
We are excited to venture into this exciting research direction with our co-investigator, Dr. Julia Cui at DEOHS and are grateful for the support from the UW EDGE Center Pilot Project Program funded by the NIEHS (P30ES007033). Congratulations to Vanessa, Ryan, and the rest of Team QACs!