With this fellowship from the National Institute of Environmental Health Sciences (F31ES037537), Ryan aims to develop a large-scale mass spectrometry database of ToxCast compounds and their metabolites and apply this database to studies of the exposome! Congratulations, Ryan! Well deserved!
Our review article on “Peroxidation rate constants and mechanisms of isoprenoid-derived lipids and their roles in ferroptosis” published in Redox Biochem. and Chem.!
This review by Noelle and Libin provides a comprehensive overview and perspective on the roles of isoprenoid-derived lipids in ferroptosis. Check out the paper here.
Our collaborative work on PubChemLite published in ES&T Letters!
This is a collaboration with Prof. Emma Schymanski at the University of Luxembourg and Dr. Evan Bolton at the PubChem of the National Center for Biotechnology Information (NCBI). Check out this paper here:
Vanessa’s paper on BACs’ impact on gut microbiome was published in Tox. Sci.!
This is a collaboration between our lab and the Cui lab in DEOHS. Check out the paper here:
Congratulations on the successful defenses by Vanessa Lopez and Tianwei Shen!
Vanessa defended her thesis on July 31, titled, “Assessing the Impact of Benzalkonium Chlorides on the Gut Microbiome and Liver Metabolism”.
Tianwei defended her thesis on August 01, titled, “Elucidation of the Role of VraTSR and Lipid Metabolism in the Development of Resistance Phenotypes in Staphylococcus aureus“.
Ryan Nguyen’s paper on the development and application of a multidimensional database of QACs and their metabolites was published in ES&T!
In this work, we developed a multidimensional database of QACs and QAC metabolites made of retention time, m/z, collision cross section, and MS/MS fragmentation and used it to identify these compounds in human fecal samples. Congratulations, Ryan N. and team! Check out the paper here.
Our collaborative paper with the Wang Lab on the transport of benzalkonium chlorides (BACs) by OCTs and hMATEs was published in Drug Metabolism and Disposition!
Congratulations to Dr. Vieira in the Joanne Wang’s Lab in the Department of Pharmaceutics and Dr. Ryan Seguin in our lab! We found that short-chain (C8 and C10) BACs are substrates of OCTs and hMATES while all BACs are inhibitors of these transporters using metformin as the probe substrate. Check out the paper here.
Emily’s paper on factors affecting the utilization of exogenous fatty acids by S. aureus was published in mSphere!
Congratulations to Emily, Rutan, Dylan and coauthors! Check out the paper here.
Congratulations to Dr. Amy Li for a successful defense!
PhD #4 from the lab! Awesome job, Amy! Her thesis title is “Temporal and spatial multi-omics characterization of Smith-Lemli-Opitz syndrome”!
The perspective authored by Quynh and Libin on how different lipid peroxidation mechanisms contribute differently to ferroptosis was published in Cell Reports Physical Science!
Check out the paper here.
