This all-in-one package, LiPydomics, contains a large experimental and predicted database of CCS and HILIC retention time, allows data processing, lipid identification with multi-dimensional data, statistical analysis, plotting, and comes with a text-based interface. The database is also available at CCSbase.net. Check out the paper here.
This is a collaboration with Prof. Brian Wilkinson at Illinois State and Prof. Francis Alonzo at Loyola U Chicago. Congrats to former postdoc, Dr. Kelly Hines! The paper was selected as the Cover Image of the issue.
Check out the paper here at Analytical Chemistry. Access the database and prediction model at https://ccsbase.net/. Congratulations, Dylan and Jang Ho!
This is a collaborative work with the Werth lab at the Department of Pharmacy and Salipante Lab at Laboratory Medicine! Check out the paper at Journal of Antimicrobial Chemotherapy: Occurrence of cross-resistance and β-lactam seesaw effect in glycopeptide-, lipopeptide- and lipoglycopeptide-resistant MRSA correlates with membrane phosphatidylglycerol levels.
Congratulations to Ryan, Josi, Vanessa, and our former rotation student Joe! Check out the paper here.
Congratulations, Dylan and Ryan!
In this work, we used a combination of sterolomics, lipidomics, and transcriptomics to investigate the consequences of sterol and lipid homeostasis in neonatal brains after in utero exposure. Check out the paper here. Update on 09/10/19, the paper was highlighted in Tox Spotlight and selected as a cover art of the issue!
Nice work, Kelly! Check out the paper here.
This study led by Profs. Kelly and Himmelfarb reported assessment of the nephrotoxicity of the antibiotic polymyxin using human kidney-on-a-chip. We carried out the analysis of sterols for this work. Congrats to Cecilia, Kelly, and Josi! Check out the paper here.
This is a review on the role of oxysterols in retinal degeneration of a rat model of Smith-Lemli-Opitz syndrome. Check out the paper here.