This is a collaboration between our lab and the Cui lab in DEOHS. Check out the paper here:
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In this work, we developed a multidimensional database of QACs and QAC metabolites made of retention time, m/z, collision cross section, and MS/MS fragmentation and used it to identify these compounds in human fecal samples. Congratulations, Ryan N. and team! Check out the paper here.
Congratulations to Dr. Vieira in the Joanne Wang’s Lab in the Department of Pharmaceutics and Dr. Ryan Seguin in our lab! We found that short-chain (C8 and C10) BACs are substrates of OCTs and hMATES while all BACs are inhibitors of these transporters using metformin as the probe substrate. Check out the paper here.
Congratulations to Emily, Rutan, Dylan and coauthors! Check out the paper here.
Check out the paper here.
Congrats to Rutan and coauthors! Check out the paper here!
Congrats, Noelle and Team! Check out the paper here.
This is a landmark review on the widely used antimicrobials, quaternary ammonium compounds (QACs)! Check it out here.
This paper aims to understand the chemical and biochemical mechanisms underlying the different potency of conjugated and nonconjugated polyunsaturated fatty acids in inducing ferroptosis. Check out the paper here.
Congratulations to Dr. Hideaki Tomita and coauthors! In this work, we investigated the impact of defective cholesterol biosynthesis at the step of DHCR7 on embryonic neurogenesis, the underlying mechanisms, and ways to rescue the neurogenesis phenotypes. Check out the paper here!