Our collaborative work with the Werth Lab in the Department of Pharmacy and the Salipante Lab in the Department of Laboratory Medicine was published in mSphere! This work reports characterization of the lipidomic changes associated with daptomycin resistance in three Gram-positive pathogens, E. faecalis, S. aureus, and C. striatum, and correlation with their genetic changes. Read the paper here.
Great job, Josi!
Congratulations to Josi on receiving the Best Poster Award at the annual meeting of Pacific Northwest Association of Toxicologists!
We welcome Quynh Do to join our graduate program and rotate with us this quarter! Look forward to working with you!
We welcome Tianwei Shen to join the Medicinal Chemistry Graduate Program and our lab! Excited to have you here, Tianwei!
Our NIH R01 proposal on Smith-Lemli-Opitz syndrome (SLOS) was awarded for five years! In this project, we will investigate the role of 7-dehydrocholesterol-derived oxysterols in neurodevelopment of SLOS. Congratulations, team!
Our paper on the measurement of collision cross sections (CCS) of over 1400 drug and drug-like molecules using traveling wave IM-MS was accepted to Analytical Chemistry! Congratulations to Kelly and Dylan, and our collaborators at the Department of Chemistry, Kim Davidson and Matt Bush! Great team effort!
Our collaborative work titled: “Enzymatic and Free Radical Formation of Cis- and Trans- Epoxyeicosatrienoic Acids In Vitro and In Vivo” in collaboration with the Totah Lab was accepted for publication in the journal Free Radical Biology and Medicine. This is the first demonstration that both trans and cis- epoxyeicosatrienoic acids (EETs) can be formed from arachidonic acid under free radical oxidation condition.
Our project “Mechanisms of Peroxyl Radical Addition Reactions” was funded by the National Science Foundation for three years! This project will investigate the fundamental chemistry of lipid peroxidation! Thanks to our members who have contributed to this project, Andrew Dinh, David Lee, and David Kennedy, and congratulations to all!
We welcome Ryan Seguin, a UW Med Chem product, to join our lab as a postdoctoral fellow! And congratulations to Ryan on receiving his Environmental Pathology/Toxicology training grant to start his new position! Way to go, Ryan!