This is a collaboration with Carrie Finno at UC-Davis, titled:”An innate immune response and altered nuclear receptor activation defines the spinal cord transcriptome during alpha-tocopherol deficiency in Ttpa-null mice”. See the paper here.
Royalty Research Fund awarded to study antibiotic resistance in S. aureus!
Our project “”Targeting Altered Lipid Metabolism in Antibiotic-Resistant Staphylococcus aureus” was awarded the UW Royal Research Fund for one year! This is a collaborative project with the Werth Lab in Department of Pharmacy. Congrats, Kelly, Tianwei, and Hideaki!
Our collaborative work on SLOS intervention was published in Scientific Reports!
This is a collaborative work with the Fliesler lab at SUNY-Buffalo titled “Prevention of Retinal Degeneration in a Rat Model of Smith-Lemli-Opitz Syndrome“. This work represents the first successful prevention of a SLOS phenotype, retinal degeneration, in an animal model! Congrats, Josi and Kelly!
Our paper on lipidomics of daptomycin-resistant Gram-positive pathogens was published in mSphere!
Our collaborative work with the Werth Lab in the Department of Pharmacy and the Salipante Lab in the Department of Laboratory Medicine was published in mSphere! This work reports characterization of the lipidomic changes associated with daptomycin resistance in three Gram-positive pathogens, E. faecalis, S. aureus, and C. striatum, and correlation with their genetic changes. Read the paper here.
Congratulations to Josi for passing her general exam!
Great job, Josi!
Josi received Best Poster Award at PANWAT!
Congratulations to Josi on receiving the Best Poster Award at the annual meeting of Pacific Northwest Association of Toxicologists!
Welcome Quynh Do!
We welcome Quynh Do to join our graduate program and rotate with us this quarter! Look forward to working with you!
Tianwei Shen joins the lab!
We welcome Tianwei Shen to join the Medicinal Chemistry Graduate Program and our lab! Excited to have you here, Tianwei!
SLOS R01 awarded!
Our NIH R01 proposal on Smith-Lemli-Opitz syndrome (SLOS) was awarded for five years! In this project, we will investigate the role of 7-dehydrocholesterol-derived oxysterols in neurodevelopment of SLOS. Congratulations, team!
Drug CCS paper accepted to Analytical Chemistry!
Our paper on the measurement of collision cross sections (CCS) of over 1400 drug and drug-like molecules using traveling wave IM-MS was accepted to Analytical Chemistry! Congratulations to Kelly and Dylan, and our collaborators at the Department of Chemistry, Kim Davidson and Matt Bush! Great team effort!
