Our collaborative project with the Werth lab in the Department of Pharmacy, entitled: “Contribution of altered lipid metabolism to resistance to cell envelope-targeting antimicrobials in MRSA”, was recently awarded a 4-year R01 grant by NIH/NIAID! Congrats to our team members who are key contributors to this project, Kelly Hines, Hideaki Tomita, and Tianwei Shen! We also appreciate earlier support from the School of Pharmacy Faculty Innovation Fund and UW Royalty Research Fund!
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Amy Li Appointed to Pharmacological Sciences Training Program!
Amy was one of 6 new trainees (out of 17) selected by the Pharmacological Sciences Training Program (PSTP) (T32GM007750) operating committee. Congrats, Amy!!!
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Welcome new summer student Tania!
Tania Ruiz Velasco joins our lab for two months through the Pharmacological Science Summer Diversity Program (PSSDP). Tania just finished her Junior year at the University of Chicago majoring in Chemistry and will be studying the effect of small molecule drugs on lipid metabolism. Welcome, Tania!
Libin, Kelly, Dylan and Amy at ASMS 2018!
June 03-07, 2018, San Diego, CA
At the posters:
A MedChem get-together:
Our collaborative work on tocopherol-deficient mice was published in FRBM!
This is a collaboration with Carrie Finno at UC-Davis, titled:”An innate immune response and altered nuclear receptor activation defines the spinal cord transcriptome during alpha-tocopherol deficiency in Ttpa-null mice”. See the paper here.
Royalty Research Fund awarded to study antibiotic resistance in S. aureus!
Our project “”Targeting Altered Lipid Metabolism in Antibiotic-Resistant Staphylococcus aureus” was awarded the UW Royal Research Fund for one year! This is a collaborative project with the Werth Lab in Department of Pharmacy. Congrats, Kelly, Tianwei, and Hideaki!
Our collaborative work on SLOS intervention was published in Scientific Reports!
This is a collaborative work with the Fliesler lab at SUNY-Buffalo titled “Prevention of Retinal Degeneration in a Rat Model of Smith-Lemli-Opitz Syndrome“. This work represents the first successful prevention of a SLOS phenotype, retinal degeneration, in an animal model! Congrats, Josi and Kelly!
Our paper on lipidomics of daptomycin-resistant Gram-positive pathogens was published in mSphere!
Our collaborative work with the Werth Lab in the Department of Pharmacy and the Salipante Lab in the Department of Laboratory Medicine was published in mSphere! This work reports characterization of the lipidomic changes associated with daptomycin resistance in three Gram-positive pathogens, E. faecalis, S. aureus, and C. striatum, and correlation with their genetic changes. Read the paper here.
Congratulations to Josi for passing her general exam!
Great job, Josi!
Josi received Best Poster Award at PANWAT!
Congratulations to Josi on receiving the Best Poster Award at the annual meeting of Pacific Northwest Association of Toxicologists!