This work identified Hedgehog signaling negatively regulate DHCR7 and positively regulate CYP7A1, leading to increases in Smo-activating oxysterol levels! Check out this paper here.
This work identified Hedgehog signaling negatively regulate DHCR7 and positively regulate CYP7A1, leading to increases in Smo-activating oxysterol levels! Check out this paper here.