This work identified Hedgehog signaling negatively regulate DHCR7 and positively regulate CYP7A1, leading to increases in Smo-activating oxysterol levels! Check out this paper here.
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This work identified Hedgehog signaling negatively regulate DHCR7 and positively regulate CYP7A1, leading to increases in Smo-activating oxysterol levels! Check out this paper here.