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Unnatural blues

This parody (written by Greg Crowther) is sung to the tune of "Natural Blues" (written and performed by Moby).


Oh, Lordy, water so hot.
Oh, Lordy, water so hot.
Don't nobody know my trouble but Darwin.
Don't nobody know my trouble but Darwin.

I am adapted to life in the lake;
Put me in a lab, and I'll acclimate.
But there is a limit to the heat I can take;
At 42 Celsius, I surely will bake.


You can keep cool with secretions of sweat;
I can't do that because I'm already wet.
So I'll swim to the shade, where the water is fine,
And pray that HSPs keep my proteins in line.



Who says fish never get the blues? This teleost is concerned that the water is becoming too darn hot. After noting that his upper lethal limit is 42 degrees Celsius, he lists the three major mechanisms ectotherms use to minimize heat-induced damage to their bodies: evaporative heat loss (e.g., sweating); relocation to cooler areas; and expression of heat shock proteins (HSPs), which help prevent other proteins from denaturing under warm conditions.

This song was written and performed for students in Biology 334B in the fall of 2002.