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This parody (written by Greg Crowther) is sung to the tune of "My Sharona" (written by Doug Fieger and Burton Averre and performed by The Knack).


Ooh my little filaments, filaments --
Actin and myosin myofibrils:
Proteins that are long and dense, long and dense,
Making up the structure of the myofibrils.

Signal from the brain rides the nerve to the muscle,
Where the myosin inside will slide past the actin of the
My-my-my-y-y, woo! Muh-muh-muh-myofibrils.

Add a little calcium, calcium
To the cytoplasm near the myofibrils.
It will turn troponin on, troponin on,
Causing the contraction of the myofibrils.


Muscles need energy, energy,
Most of which is needed by the myofibrils.
Myosin burns ATP, ATP
Fueling the contractions of the myofibrils.



This song outlines the molecular mechanisms by which muscles contract.

Other Files

MP3 (by Science Groove)