| UW Anesthesiology & Pain Faculty Research| This page provides a list of faculty mentors in the department who are happy to work with residents, and their research interests and projects. |  |
| Basic Science | ||
|---|---|---|
| Bentov, Itay MD | (Basic, Clinical) | (1) The effect of anesthetics on insulin like Growth factor-1 mediated wound healing in the aged (2) Frailty assessment and intraoperative hemodynamics to determine postoperative outcomes in the aged |
| Crowder, Michael MD PhD | (Basic) | (1) The Crowder lab uses molecular genetic and high throughput drug screening methods to identify novel determinants of hypoxic cellular injury and develop effective means for prevention or recover |
| Morgan, Philip MD | (Basic) | (1) Understanding the mechanism of action of volatile anesthetics, using a mouse model of mitochondrial dysfunction (2) Investigating the pathways that control anesthetic induced neurotoxicity in early development |
| Raftery, Daniel PhD | (Basic, Translational) | (1) Our lab focuses on metabolomics, the study of metabolism using advanced analytical methods. We are interested in a variety of areas related to anesthesia - hypoxia: brain or peripheral, anesthetic: more broadly drug response, cardiac function as measured through metabolism, mitochondrial status and response, etc. |
| Sedensky, Margaret MD | (Basic) | (1) Understanding the mechanism of action of volatile anesthetics, using a mouse model of mitochondrial dysfunction (2) Investigating the pathways that control anesthetic induced neurotoxicity in early development |
| Tian, Rong MD, PhD | (Basic, Translational) | (1) Study the effects of inhalational anesthetics on donor liver mitochondrial function and the outcome of transplant (2) Mitochondrial function of the peripheral blood mononucleated cells (PBMC) as a determinant of inflammatory response |
| Wang, Wang MD, PhD | (Basic) | (1) Investigating the link between metabolic stress, redox imbalance, and hyper-active mitochondrial dynamics in metabolic heart disease (2) Elucidating the new regulatory mechanisms for energy metabolism in the heart and provide new targets for treating heart failure (3) Determination of mitochondrial calcium regulation in the diseased heart and how it contributes to the development of heart hypertrophy and failure. |
| Airway | ||
|---|---|---|
| Joffe, Aaron DO | (Clinical) | (1) Currently airway database related. Does nighttime extubation increase the risk of reintubation and poor outcomes? Large review of extubation related outcomes related to daytime or nighttime extubation. |
| Patrao, Fiona MBBS | (Clinical) | (1) Working along with Drs. Agnes Hunyady and Kate Gentry to assess airway length based on preexisting CT scans in patients such as Pierre Robin to assess appropriate ETT sizing. A lot of the groundwork has already been done, and this may be an excellent resident project to complete in a few months. |
| Cardiothoracic | ||
|---|---|---|
| Jelacic, Srdjan MD | (Quality Improvement) | (1) Evaluating the use of routine video recording for identification of specific intraoperative hazards-computerized perioperative checklists use, drug administration safety, anesthesia infection control, distraction, noise level and sentinel events |
| Raftery, Daniel PhD | (Basic, Translational) | (1) Our lab focuses on metabolomics, the study of metabolism using advanced analytical methods. We are interested in a variety of areas related to anesthesia - hypoxia: brain or peripheral, anesthetic: more broadly drug response, cardiac function as measured through metabolism, mitochondrial status and response, etc. |
| Ross, Faith MD | (Translational, Clinical) | (1) Comparison of invasive and non-invasive blood pressure measurement in anesthetized children, prospective trial (2) Impact of malnutrition on outcomes after pediatric cardiac surgery, National Database review (3) Evaluation of non-heparin anticoagulants on children undergoing cardiopulmonary bypass, International database collection (4) Evaluation of anemia and hypoperfusion in infants using muscle oximetry, Prospective trial (5) Series of review articles on anesthetic management for specific congenital heart lesions, Review articles |
| Tian, Rong MD, PhD | (Basic, Translational) | (1) Study the effects of inhalational anesthetics on donor liver mitochondrial function and the outcome of transplant (2) Mitochondrial function of the peripheral blood mononucleated cells (PBMC) as a determinant of inflammatory response |
| Togashi, Kei MD | (Translational, Clinical) | (1) Please inquire |
| Wang, Wang MD, PhD | (Basic) | (1) Investigating the link between metabolic stress, redox imbalance, and hyper-active mitochondrial dynamics in metabolic heart disease (2) Elucidating the new regulatory mechanisms for energy metabolism in the heart and provide new targets for treating heart failure (3) Determination of mitochondrial calcium regulation in the diseased heart and how it contributes to the development of heart hypertrophy and failure. |
| Critical Care | ||
|---|---|---|
| Joffe, Aaron DO | (Clinical) | (1) Currently airway database related. Does nighttime extubation increase the risk of reintubation and poor outcomes? Large review of extubation related outcomes related to daytime or nighttime extubation. |
| Khandelwal, Nita MD | (Health services) | (1) Several projects using both big data and local (HMC/UWMC) data to evaluate the effectiveness of palliative care interventions in reducing ICU costs/utilization while simultaneously improving quality of care |
| Lele, Abhijit MBBS, MD, MS | (Clinical, Quality Improvement) | (1) Communication patterns in neurocritical care unit |
| Raftery, Daniel PhD | (Basic, Translational) | (1) Our lab focuses on metabolomics, the study of metabolism using advanced analytical methods. We are interested in a variety of areas related to anesthesia - hypoxia: brain or peripheral, anesthetic: more broadly drug response, cardiac function as measured through metabolism, mitochondrial status and response, etc. |
| Tian, Rong MD, PhD | (Basic, Translational) | (1) Study the effects of inhalational anesthetics on donor liver mitochondrial function and the outcome of transplant (2) Mitochondrial function of the peripheral blood mononucleated cells (PBMC) as a determinant of inflammatory response |
| Togashi, Kei MD | (Translational, Clinical) | (1) Please inquire |
| Vavilala, Monica MD | (Translational, Clinical, Educational, Quality Improvement) | (1) Faculty at HIPRC have a number of ongoing projects. Please inquire. |
| Resident Education | ||
|---|---|---|
| Dale, Rebecca MD | (Educational, Quality Improvement) | (1) Instituting a flip the classroom approach to pain medicine didactics for fellows (2) Instituting a cadaver workshop for fellows (3) Use of methadone in hospitalized patients with acute pain and co-existing opioid substance use disorder: a QI study |
| General OR | ||
|---|---|---|
| Bramhall, John MD, PhD | (Quality Improvement) | (1) General organizational QI initiatives on OR and AAP scheduling and staffing. |
| Grigg, Eliot MD | (Quality Improvement) | (1) Operating Room design and medication safety (2) Evaluating the effect of the anesthesia medication template on medication errors and cognitive load (3) Other design projects as well: medication transport |
| Kim, Jerry MD | (Translational) | (1) Improving the prediction of intraoperative adverse events, such as hypoxemia, using machine learning algorithms, artificial intelligence, and big data. |
| Patak, Lance MD | (Clinical) | (1) Measuring impact of ultrasound training and difficult IV algorithm on number of attempts and time to placement of IVs in the OR (2) Impact of communication technologies on outcomes for critically ill patients |
| Van Cleve, Wil MD | (Clinical) | (1) Performing a database-driven study of existing health records to determine the effect of propofol infusion on the risk of PONV (2) Studying the risk of PDPH in a large dataset of private health insurance claims, as well as relevant outcomes-increased healthcare costs |
| Geriatric | ||
|---|---|---|
| Bentov, Itay MD | (Basic, Clinical) | (1) The effect of anesthetics on insulin like Growth factor-1 mediated wound healing in the aged (2) Frailty assessment and intraoperative hemodynamics to determine postoperative outcomes in the aged |
| Neuroanesthesia | ||
|---|---|---|
| Jardine, David MD | (Translational) | (1) We are studying biomarkers of anesthesia neurotoxicity in infancy |
| Morgan, Philip MD | (Basic) | (1) Understanding the mechanism of action of volatile anesthetics, using a mouse model of mitochondrial dysfunction (2) Investigating the pathways that control anesthetic induced neurotoxicity in early development |
| Sedensky, Margaret MD | (Basic) | (1) Understanding the mechanism of action of volatile anesthetics, using a mouse model of mitochondrial dysfunction (2) Investigating the pathways that control anesthetic induced neurotoxicity in early development |
| Vavilala, Monica MD | (Translational, Clinical, Educational, Quality Improvement) | (1) Faculty at HIPRC have a number of ongoing projects. Please inquire. |
| Obstetric | ||
|---|---|---|
| Bollag, Laurent MD | (Clinical, Educational, Quality Improvement) | (1) Case report (2) Clinical outcomes research |
| Delgado Upegui, Carlos MD | (Clinical) | (1) An echocardiographic assessment of left ventricle location in parturients - an insight into cardiopulmonary resuscitation. Aim: To study the effect of the gravid uterus with left uterine displacement on the position of the maternal left ventricle. Hypothesis: 1. In supine pregnant patients, the inter-nipple line is dynamic and should therefore not be used as a landmark for hand placement recommendations. 2. The intrathoracic structure just underneath the lower third of the sternum-the most easily recognizable solid anatomical structure in the pregnant anterior chest-is the left ventricle in only a minority of pregnant patients |
| Van Cleve, Wil MD | (Clinical) | (1) Performing a database-driven study of existing health records to determine the effect of propofol infusion on the risk of PONV (2) Studying the risk of PDPH in a large dataset of private health insurance claims, as well as relevant outcomes-increased healthcare costs |
| Pain | ||
|---|---|---|
| Bhananker, Sanjay MB BS | (Clinical) | (1) Postoperative pain relief using Oliceridine (2) Liposomal bupivacaine for various surgeries in pediatric age group (3) Incidence of Residual paralysis in PACU (4) Retrospective review of brachial plexus blocks - effectiveness and complications (5) Educational research that has been conducted, but not published - Needs help with writing it up |
| Bollag, Laurent MD | (Clinical, Educational, Quality Improvement) | (1) Case report (2) Clinical outcomes research |
| Canlas, Bernard MD | (Clinical) | (1) My team is focusing on functional restoration pain programs for the Veterans. The focus is on non- opioid management |
| Curatolo, Michele MD | (Translational, Clinical, Quality Improvement) | (1) Predictors of chronic post-traumatic pain (2) Role of hyperalgesia in the outcome of rehabilitation on low back pain (3) Outcome of occipital nerve blocks in headache (4) Immune markers of fibromyalgia and chronic temporomandibular disorder |
| Dale, Rebecca MD | (Educational, Quality Improvement) | (1) Instituting a flip the classroom approach to pain medicine didactics for fellows (2) Instituting a cadaver workshop for fellows (3) Use of methadone in hospitalized patients with acute pain and co-existing opioid substance use disorder: a QI study |
| Krashin, Daniel MD | (Clinical) | (1) Please inquire. |
| Law, Emily PhD | (Clinical) | (1) Characterizing psychosocial risk in youth with chronic migraine using prospective questionnaire measures |
| Loland, Vanessa MD | (Clinical, Quality Improvement) | (1) Present study, already have funding and IRB approval - just starting to enroll patients. Factors-psychological, physical, pharmacological- influencing speed and quality of recovery after ACL surgery comparing Femoral Nerve block to Adductor Canal block (2) QI project: Looking at post op follow up after shoulder surgery-pain scores, medication use, rebound pain, satisfaction scores-comparing no block, to single shot, to catheter (3) Using pilot data from above QI project, we will attempt to get funding to put together a study to look at the rate of rebound pain comparing interscalene catheters v/s single shots, versus no blocks on these same shoulder patients |
| Palermo, Tonya PhD | (Clinical) | (1) Evaluation of the implementation and effectiveness of an app for self-management of chronic pain in youth in a prospective clinical trial (2) Examining trajectories of pain symptoms in children during the waiting period for a chronic pain clinic evaluation (3) Evaluation of the feasibility and efficacy of an internet-delivered pain self-management program for children with chronic pancreatitis in a prospective clinical trial (4) Evaluation of the feasibility and efficacy of an internet-delivered pain self-management program for adults with chronic pancreatitis in a prospective clinical trial |
| Rozet, Irene MD | (Translational, Clinical, Quality Improvement) | (1) Ketamine for anesthesia in electroconvulsive treatment in major depression (2) Postoperative development of chronic postoperative pain (3) Perioperative QI Projects: - perioperative protocol development for drug users; smoking cessation; perioperative aspirin; fragility as a predictor of postoperative mortality and others |
| Sharar, Samuel MD | (Translational, Clinical, Quality Improvement) | (1) Clinical research in pain management - applications of virtual reality technologies to pain management, including VR distraction and VR hypnosis (2) QI research in trauma care - assessment of trauma system development and protocols specific to prehospital airway management, pediatric trauma splenectomies, and trauma anesthesia training/resources |
| Stacey, Brett MD | (Clinical) | (1) Please inquire |
| Tham, See Wan MB BS | (Clinical) | (1) Examining the trajectory of sleep, pain and postconcussion symptoms in adolescents after concussion with prospective evaluation (2) Examine the impact of sleep duration on pain response in adolescents using a randomized cross over study design |
| Wu, Jiang MD | (Clinical, Quality Improvement) | (1) Case report: Use of Dexmedetomidine for refractory postoperative pain following spine fusion surgery in a highly- opioids tolerant patient (2) Case report: post-op pain management for patient with lock-in syndrome following ex-lap for nephrectomy |
| Palliative Care | ||
|---|---|---|
| Khandelwal, Nita MD | (Health services) | (1) Several projects using both big data and local (HMC/UWMC) data to evaluate the effectiveness of palliative care interventions in reducing ICU costs/utilization while simultaneously improving quality of care |
| Pediatric | ||
|---|---|---|
| Bhananker, Sanjay MB BS | (Clinical) | (1) Postoperative pain relief using Oliceridine (2) Liposomal bupivacaine for various surgeries in pediatric age group (3) Incidence of Residual paralysis in PACU (4) Retrospective review of brachial plexus blocks - effectiveness and complications (5) Educational research that has been conducted, but not published - Needs help with writing it up |
| Bosenberg, Adrian MB ChB | (Clinical) | (1) Regional anesthesia - variety of subjects |
| Gentry, Katherine MD | (Clinical) | (1) Census survey of pediatric anesthesiologists regarding attitudes about the new FDA warning regarding neurotoxicity and their informed consent practices.
(2) Qualitative analysis of informed consent discussions in pediatric anesthesia looking at what questions parents ask and how anesthesiologists respond (3) Comparison of airway dimensions in children with Robin sequence and healthy controls using retrospective chart review in collaboration with Agnes Hunyady. |
| Grigg, Eliot MD | (Quality Improvement) | (1) Operating Room design and medication safety (2) Evaluating the effect of the anesthesia medication template on medication errors and cognitive load (3) Other design projects as well: medication transport |
| Hunyady, Agnes MD | (Clinical) | (1) Comparison of airway dimensions in children with Robin sequence and healthy controls (retrospective chart review) in collaboration with Agnes Hunyady |
| Jardine, David MD | (Translational) | (1) We are studying biomarkers of anesthesia neurotoxicity in infancy |
| Jimenez, Nathalia MD, MPH | (Clinical, Epidemiology, Public Health) | (1) Multiple studies, on outcomes after TBI among Hispanic children |
| Law, Emily PhD | (Clinical) | (1) Characterizing psychosocial risk in youth with chronic migraine using prospective questionnaire measures |
| Liston, David MD | (Clinical) | (1) Comparing PCA, LEA and LPC in pediatric hip surgery, 2) Use of simulation to improve interdepartmental team work in pediatric airway emergencies |
| Low, Daniel MD, MB BS | (Clinical, Quality Improvement) | (1) Writing a software solution code named Q, which will allow physicians to self service from the EMR database to select cohorts of patients e.g ASA 1, tonsillectomy, who got morphine 0.1mg/kg etc. Define outcome metrics e.g PACU length of stay, max pain score, opiate rescue rate, PONV rate. Allows a direct comparison against a second or third cohort. Stats and graphical output of outcome metrics all built in. These chart review projects that take 10-15 weeks will take 2-3 minutes to run! |
| Martin, Liz MD | (Quality Improvement) | (1) Pediatric Anesthesia /Pediatric Regional Anesthesia outcomes research (2) Medication Safety |
| Palermo, Tonya PhD | (Clinical) | (1) Evaluation of the implementation and effectiveness of an app for self-management of chronic pain in youth in a prospective clinical trial (2) Examining trajectories of pain symptoms in children during the waiting period for a chronic pain clinic evaluation (3) Evaluation of the feasibility and efficacy of an internet-delivered pain self-management program for children with chronic pancreatitis in a prospective clinical trial (4) Evaluation of the feasibility and efficacy of an internet-delivered pain self-management program for adults with chronic pancreatitis in a prospective clinical trial |
| Patrao, Fiona MBBS | (Clinical) | (1) Working along with Drs. Agnes Hunyady and Kate Gentry to assess airway length based on preexisting CT scans in patients such as Pierre Robin to assess appropriate ETT sizing. A lot of the groundwork has already been done, and this may be an excellent resident project to complete in a few months. |
| Ross, Faith MD | (Translational, Clinical) | (1) Comparison of invasive and non-invasive blood pressure measurement in anesthetized children, prospective trial (2) Impact of malnutrition on outcomes after pediatric cardiac surgery, National Database review (3) Evaluation of non-heparin anticoagulants on children undergoing cardiopulmonary bypass, International database collection (4) Evaluation of anemia and hypoperfusion in infants using muscle oximetry, Prospective trial (5) Series of review articles on anesthetic management for specific congenital heart lesions, Review articles |
| Rubens, Daniel MB BS, FANZCA | (Clinical, Translational) | (1) Understanding the mechanism of sudden infant death syndrome, with a piglet project underway in Denmark and an epidemiological study of infants in England |
| Vavilala, Monica MD | (Translational, Clinical, Educational, Quality Improvement) | (1) Faculty at HIPRC have a number of ongoing projects. Please inquire. |
| Perioperative | ||
|---|---|---|
| Bentov, Itay MD | (Basic, Clinical) | (1) The effect of anesthetics on insulin like Growth factor-1 mediated wound healing in the aged (2) Frailty assessment and intraoperative hemodynamics to determine postoperative outcomes in the aged |
| Bhananker, Sanjay MB BS | (Clinical) | (1) Postoperative pain relief using Oliceridine (2) Liposomal bupivacaine for various surgeries in pediatric age group (3) Incidence of Residual paralysis in PACU (4) Retrospective review of brachial plexus blocks - effectiveness and complications (5) Educational research that has been conducted, but not published - Needs help with writing it up |
| Horibe, Mayumi MD | (Translational) | (1) Perioperative glucose control at UW OR (2) Continuous glucose monitor in perioperative period |
| Palermo, Tonya PhD | (Clinical) | (1) Evaluation of the implementation and effectiveness of an app for self-management of chronic pain in youth in a prospective clinical trial (2) Examining trajectories of pain symptoms in children during the waiting period for a chronic pain clinic evaluation (3) Evaluation of the feasibility and efficacy of an internet-delivered pain self-management program for children with chronic pancreatitis in a prospective clinical trial (4) Evaluation of the feasibility and efficacy of an internet-delivered pain self-management program for adults with chronic pancreatitis in a prospective clinical trial |
| Patak, Lance MD | (Clinical) | (1) Measuring impact of ultrasound training and difficult IV algorithm on number of attempts and time to placement of IVs in the OR (2) Impact of communication technologies on outcomes for critically ill patients |
| Rozet, Irene MD | (Translational, Clinical, Quality Improvement) | (1) Ketamine for anesthesia in electroconvulsive treatment in major depression (2) Postoperative development of chronic postoperative pain (3) Perioperative QI Projects: - perioperative protocol development for drug users; smoking cessation; perioperative aspirin; fragility as a predictor of postoperative mortality and others |
| Van Cleve, Wil MD | (Clinical) | (1) Performing a database-driven study of existing health records to determine the effect of propofol infusion on the risk of PONV (2) Studying the risk of PDPH in a large dataset of private health insurance claims, as well as relevant outcomes-increased healthcare costs |
| Regional | ||
|---|---|---|
| Liston, David MD | (Clinical) | (1) Comparing PCA, LEA and LPC in pediatric hip surgery, 2) Use of simulation to improve interdepartmental team work in pediatric airway emergencies |
| Loland, Vanessa MD | (Clinical, Quality Improvement) | (1) Present study, already have funding and IRB approval - just starting to enroll patients. Factors-psychological, physical, pharmacological- influencing speed and quality of recovery after ACL surgery comparing Femoral Nerve block to Adductor Canal block (2) QI project: Looking at post op follow up after shoulder surgery-pain scores, medication use, rebound pain, satisfaction scores-comparing no block, to single shot, to catheter (3) Using pilot data from above QI project, we will attempt to get funding to put together a study to look at the rate of rebound pain comparing interscalene catheters v/s single shots, versus no blocks on these same shoulder patients |
| Martin, Liz MD | (Quality Improvement) | (1) Pediatric Anesthesia /Pediatric Regional Anesthesia outcomes research (2) Medication Safety |
| Transplant | ||
|---|---|---|
| Fukazawa, Kyota MD | (Clinical) | (1) Investigation of immediate death of recipient after transplant due to pulmonary embolism (2) Recipient and donor characteristics associated with increased risk for de novo cancer in liver transplant (3) Size-mismatch between donor and recipient, and associated outcome (4) Pulmonary function and post-transplant outcome (5) Hepato-pulmonary syndrome in liver transplantation (6) Immediate post-transplant mortality study (7) Other clinical retrospective studies related to kidney/liver/pancreas transplant |
| Tian, Rong MD, PhD | (Basic, Translational) | (1) Study the effects of inhalational anesthetics on donor liver mitochondrial function and the outcome of transplant (2) Mitochondrial function of the peripheral blood mononucleated cells (PBMC) as a determinant of inflammatory response |