Research focus:
Nanotechnology for mucosal vaccine delivery.

Publications:

• 1. Frizzell, H., Ohlsen, T. J., Woodrow, K. A. (2017) Development and optimization of protein-loaded electrospun fibers with pH-controlled release, high bioactivity, and enhanced stability. International Journal of Pharmaceutics.
• 2. Frizzell, H., Park, J., Lou Comandante, N., Woodrow, K. A. (2016). Role of heterogeneous cell population on modulation of dendritic cell phenotype and activation of CD8 T cells for use in cell-based immunotherapies. Cellular Immunology.
• 3. Forbes D.C., Creixell, M., Frizzell H., Peppas, N.A. (2013) Polycationic nanoparticles synthesized using ARGET ATRP for drug delivery. European Journal of Pharmaceutics and Biopharmaceutics.



Presentations:

• 1. Frizzell, H., Woodrow, K. A. "Optimization of Protein-Loaded Electrospun Fibers for Targeted Intestinal Delivery," Biomedical Engineering Society Annual Meeting. October 11 – 14, 2017, Phoenix, Arizona. Oral Presentation.
• 2. Frizzell, H., Park, J., Lou Comandante, N., Woodrow, K. A. "Dendritic Cell Priming in Heterogeneous Cultures Modulates Phenotype and Function for Immunotherapy," Biomedical Engineering Society Annual Meeting. October 11 – 14, 2017, Phoenix, Arizona. Oral Presentation.
• 3. Frizzell, H. "Making Vaccines Less of a Pain," Town Hall Seattle. April 11, 2017, Seattle, Washington. Oral Presentation.
• 4. Frizzell, H., Woodrow, K.A. "Development of bioactive protein-loaded electrospun fibers with pH-controlled release for oral delivery," Biomaterials Seminar. October 10, 2016, Seattle, Washington. Oral Presentation.
• 5. Frizzell, H., Forbes, D.C., Peppas, N.A. "Oral Delivery of siRNA using pH-Responsive Hydrogel Nanoparticles," Biomaterial's Day. May 31, 2013, Austin, Texas. Poster.
• 6. Forbes, D.C., Creixell, M., Frizzell, H., Peppas, N.A. "Two-part Oral siRNA Delivers Systems for the Treatment of Colon Cancer," Cancer Prevention Research Institute of Texas. October 24, 2012, Austin, Texas. Poster.
• 7. Frizzell, H., Forbes, D.C., Peppas, N.A. "Two-part Oral siRNA Delivery Systems: Polycationic Hydrogel Nanoparticles and Alginate Matrices," Biomaterials Day. July 27, 2012, Houston, Texas. Poster.
• 8. Forbes, D.C., Frizzell, H., Peppas, N.A. "Comparing ARGET ATRP with Traditional Free Radical Polymerization for Versatile Polycationic Hydrogel Nanoparticles," Biomaterials Day. July 27, 2012, Houston, Texas. Poster.


Honors and Awards:

• National Science Foundation Graduate Research Opportunities Worldwide Fellowship (2017); Society of Women Engineers WE15 Conference Scholarship, sponsored by Microsoft (2015); National Science Foundation Graduate Research Fellowship (2014—current); Roche/Achievement Rewards for College Scientists (ARCS) Foundation Fellowship (2014—current); Graduate with Honors, The University of Texas at Austin (2014); First Place Undergraduate Poster Presentation Competition, Biomaterials Day, Rice University (2013); Undergraduate Research Fellowship, The University of Texas at Austin (2012—2013); Russell U. Smith Family Endowed Scholarship, The University of Texas at Austin (2012—2013); Texas Exes Scholarship, The University of Texas at Austin (2009—2010).

Research focus:
Antiretroviral drug synergy in nanoparticle systems; biomaterials approaches to HIV prevention and treatment.

Publications:

• 1. Akilbekova, D., Philiph, R., Graham, A. & Bratlie, K. M. Macrophage reprogramming: Influence of latex beads with various functional groups on macrophage phenotype and phagocytic uptake in vitro. J. Biomed. Mater. Res. A 103, 262-268 (2015).
• 2. Lindemann, W. R., Philiph, R., Chan, D.W.W., Ayers, C.T., Perez, E.M., Beckman, S.P., Strzalka, J., Chaudhary, S., Vaknin, D. Oriented polyvinylidene fluoride-trifluoroethylene (P(VDF-TrFE)) films by Langmuir-Blodgett deposition: a synchrotron X-ray diffraction study. Phys. Chem. Chem. Phys. (2015). doi:10.1039/C5CP04307G


Presentations:

• 1. Non-viral gene delivery using modified poly-L-lysine, R Philiph*, KM Bratlie, Presented at the Iowa State University Honors Program Poster Symposium, Ames, IA, 2015, poster presentation.
• 2. Macrophase separation using block copolymer blends, R Philiph*, C Oser, S Nicaise, K Berggren, Presented at the Iowa State University Symposium on Undergraduate Research and Creative Expression, Ames, IA, 2014, oral presentation.
• 3. Macrophase separation using block copolymer blends, R Philiph*, C Oser, S Nicaise, K Berggren, Presented at the MIT Summer Research Symposium, Cambridge, MA, 2013, poster presentation.
*Presenting author


Honors and Awards:

• National Science Foundation Graduate Fellowship (2016—current); Summa cum laude honors, Iowa State University (2015); Graduate with Honors, Iowa State University (2015); Goldwater Scholar (2014—2015); Tau Beta Pi Scholar (2014—2015); Cardinal Key Honor Society (Spring 2014-Present); High Scholarship Recognition, Iowa State University (2012, 2014, 2015); Tau Beta Pi Engineering Honor Society (Fall 2013-Present); Iowa State University Honors Program (Fall 2011-Spring 2015); Alcoa Scholarship Fund, Iowa State University (Fall 2014-Spring 2015); Dr. S. Sourirajan Materials Science Scholarship, Iowa State University (Fall 2013-Spring 2015); Award for Competitive Excellence, Iowa State University (Fall 2011-Spring 2015).

Research focus:
Biomaterials for a permanent contraceptive method; biomaterials for drug delivery.

Presentations:

• 1. J.L. Hernandez, A.K. Blakney, B.H. Katz, J.T. Jensen, K.A. Woodrow, "Optimization of drug loaded electrospun fibers to induce fibrosis of the utero-tubal junction," University of Washington Biomaterial Seminar, Seattle, Washington, November 9, 2017, oral presentation.
• 2. J.L. Hernandez, A.K. Blakney, B.H. Katz, J.T. Jensen, K.A. Woodrow, "Optimization of drug loaded electrospun fibers to induce fibrosis of the utero-tubal junction," Biomedical Engineering Society Annual Meeting, Phoenix, Arizona, October 13, 2017, poster presentation.
• 3. D.X. Whittier, S. Iles, C. Gilchrist, J.L. Hernandez, P. Moya, T.D. Toth, "On-Slide Reagent Concentration Feedback and Control," The University of Arizona Engineering Design Day, Tucson, Arizona, May, 2, 2016, poster presentation.
• 4. J.L. Hernandez, C.N. MacIsaac, J.P. Vande Geest, "Device to cell seed small diameter electrospun vascular grafts," Biomedical Engineering Design Day, Tucson, Arizona, March 2, 2016, poster presentation.
• 5. J.L. Hernandez, C.N. MacIsaac, J.P. Vande Geest, "Device to cell seed small diameter electrospun vascular grafts," Undergraduate Biology Research Program Conference, Tucson, Arizona, January 23, 2016, poster presentation.
• 6. J.L. Hernandez, C.N. MacIsaac, J.P. Vande Geest, "Device to cell seed small diameter electrospun vascular grafts," Annual Biomedical Research Conference for Minority Students, Seattle, Washington, November 13, 2015, poster presentation.
• 7. J.L. Hernandez, H. Kantamneni, M. Zevon, V. Ganapathy, P.V. Moghe, "Engineering Lymphatic Vasculature Models for Cancer Surveillance," Research in Science and Engineering Summer Research Symposium, Piscataway, New Jersey, July 17, 2015, oral and poster presentations.
• 8. J.L. Hernandez, E. Tamimi, D.C. Ardila, C.N. MacIsaac, J.A. Uhlorn, J.P. Vande Geest, "Non-synthetic Electrospun Scaffold for a Tissue Engineered Vascular Graft to Model Porcine Coronary Arteries," Undergraduate Biology Research Program Conference, Tucson, Arizona, January 24, 2015, poster presentation.
• 9. J.L. Hernandez, E. Tamimi, D.C. Ardila, C.N. MacIsaac, J.A. Uhlorn, J.P. Vande Geest, "Non-synthetic Electrospun Scaffold for a Tissue Engineered Vascular Graft to Model Porcine Coronary Arteries," Annual Biomedical Research Conference for Minority Students, San Antonio, Texas, November 13, 2014, poster presentation.
• 10. J.L. Hernandez, E. Tamimi, D.C. Ardila, C.N. MacIsaac, J.A. Uhlorn, J.P. Vande Geest, "Non-synthetic Electrospun Scaffold for a Tissue Engineered Vascular Graft to Model Porcine Coronary Arteries," Biomedical Engineering Design Day, Tucson, Arizona, October 24, 2014, poster presentation.
• 11. J.L. Hernandez, E. Tamimi, D.C. Ardila, C.N. MacIsaac, J.A. Uhlorn, J.P. Vande Geest, "Non-synthetic Electrospun Scaffold for a Tissue Engineered Vascular Graft to Model Porcine Coronary Arteries," Undergraduate Research Opportunities Consortium Conference, Tucson, Arizona, August 11, 2014, oral and poster presentations.


Honors and Awards:

• Achievement Rewards for College Scientists (ARCS) Foundation Fellowship (2016 — current); Honorable Mention, 2017 National Science Foundation Graduate Research Fellowship Program; Raytheon Award for Best Overall Design, The University of Arizona Engineering Design Day (May 2, 2016); Maximizing Access to Research Careers (MARC) Scholar, The University of Arizona (2014 – 2015); Arizona Board of Regent's High Honors Tuition Scholarship (2012-2016).

Research focus:
Biomaterials for nonsurgical permanent contraception.

Presentations:

• 1. VanBenschoten, H., Bainbridge, P., Cluckey, D., Lim, R. “Engineering a Neural Organoid Interface” Boston University Biomedical Engineering Senior Design Conference, Boston, MA, 2018, oral presentation.
• 2. VanBenschoten, H., Lim, R. “Engineering a Neural Organoid Interface” Kilachand Honors College Keystone Symposium, Boston, MA, 2018, poster presentation.


Honors and Awards:

• Summa Cum Laude Honors, Boston University (2018); Tau Beta Pi Scholar (2017-2018); Alpha Eta Mu Beta Scholar (2017-2018); Undergraduate Research Opportunities Fellowship, Boston University (Spring 2016, Spring 2017); Kilachand Honors College Summer Research Fellow, Boston University (2016); Kilachand Honors College, Boston University (2014-2018); Presidential Scholar, Boston University (2014-2018)