Brian Browning

Professor
University of Washington
Department of Medicine, Division of Medical Genetics
Health Sciences Building, K-253
Box 357720
Seattle, WA 98195-7720

E-mail: browning@uw.edu

Software

Beagle	performs genotype phasing and imputation.
flare	performs local ancestry inference.
ibd-ends	performs probabilistic estimation of IBD segment endpoints.
hap-IBD	detects identity-by-descent segments.
Refined IBD	detects identity-by-descent segments using a haplotype frequency model.
SPrime	detects introgressed genetic variants.
Utilities	utility programs for manipulating data files.
Conform-GT	converts allele strands in a target VCF file to match a reference file.
IBDseq	detects identity-by-descent segments using allele frequencies.
IBDNe	estimates effective population size in recent generations.
SEQERR	estimates genotype error rates for whole-genome sequence data.
Presto	computes order statistic distributions and multiple-testing-adjusted p-values for genome-wide association studies.
BeagleCall	performs SNP array genotype calling using linkage disequilibrium.

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Selected Publications

B L Browning, X Tian, Y Zhou, S R Browning (2021). Fast two-stage phasing of large-scale sequence data. The American Journal of Human Genetics 108(10):1880-1890. doi:10.1016/j.ajhg.2021.08.005
S R Browning, B L Browning (2020). Probabilistic estimation of identity by descent segment endpoints. The American Journal of Human Genetics 107(5):895-910. doi:10.1016/j.ajhg.2020.09.010
Y Zhou, S R Browning, B L Browning (2020). A fast and simple method for detecting identity by descent segments in large-scale data. The American Journal of Human Genetics 106(4):426-437. doi:10.1016/j.ajhg.2020.02.010
B L Browning, Y Zhou, S R Browning (2018). A one penny imputed genome from next generation reference panels. The American Journal of Human Genetics 103(3):338-348. doi:10.1016/j.ajhg.2018.07.015
B L Browning, S R Browning (2016). Genotype imputation with millions of reference samples. The American Journal of Human Genetics 98(1):116-126. doi:10.1016/j.ajhg.2015.11.020
B L Browning and S R Browning (2009). A unified approach to genotype imputation and haplotype phase inference for large data sets of trios and unrelated individuals. The American Journal of Human Genetics 84:210-223. doi:10.1016/j.ajhg.2009.01.005
S R Browning and B L Browning (2007). Rapid and accurate haplotype phasing and missing-data inference for whole-genome association studies by use of localized haplotype clustering. The American Journal of Human Genetics 81:1084-1097. doi:10.1086/521987

Publons citation data

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