PRESTO: Genetic Association Analysis Software

Program: PRESTO
Version: 1.0.1
Copyright (c) 2007-8 Brian L. Browning
This page was last updated on 15 June 2010

All rights reserved



PRESTO is optimized software for permutation testing and for computing empirical distributions of order statistics via permutation. PRESTO is extremely fast and can efficiently analyze data from one and two-stage whole genome association studies with millions of markers genotyped on thousands of samples. PRESTO can

PRESTO is written in Java and runs on most computing platforms (e.g. Windows, Linux, Unix, Solaris, Mac).

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If you use PRESTO in a published analysis, please cite

B L Browning (2008) PRESTO: Rapid calculation of order statistic distributions and multiple-testing adjusted P-values via permutation for one and two-stage genetic association studies. BMC Bioinformatics 9:309. Available from

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Download PRESTO 1.0.1

PRESTO is a software program genetic association analysis. Because PRESTO (the program) is licensed free of charge, there is NO WARRANTY for the program, to the extent permitted by applicable law. Brian Browning (the copyright holder) and/or other parties provide the program "as is" without warranty of any kind, either expressed or implied, including, but not limited to, the implied warranties of merchantability and fitness for a particular purpose. The entire risk as to the quality and performance of the program is with you. Should the program prove defective, you assume the cost of all necessary servicing, repair or correction.

In no event unless required by applicable law or agreed to in writing will any copyright holder be liable to you for damages, including any general, special, incidental or consequential damages arising out of the use or inability to use the program (including but not limited to loss of data or data being rendered inaccurate or losses sustained by you or third parties or a failure of the program to operate with any other programs), even if such holder or other party has been advised of the possibility of such damages.

The PRESTO 1.0.1 software distribution includes the following files:

  1. presto_1.0.pdf: The documentation for PRESTO 1.0
  2. presto.jar: The executable file for running PRESTO
  3. example: A folder containing 1 input file and 3 output files from an analysis described in the PRESTO 1.0 documentation.
  4. utility: A folder containing a utility program for formatting input files for PRESTO analysis. The utility program is described in the PRESTO 1.0 documentation
Brian Browning grants you permission to use PRESTO version 1.0.1 for commercial or academic research. If you understand PRESTO is distributed without warranty, and would like to download PRESTO click here.

To download a short R script for creating QQ-plots, click here

To download the java source code for PRESTO, click here.

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Version History

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