Toby Bradshaw and a pair of Harris' hawksH.D. "Toby" Bradshaw
Washington Research Foundation Professor of Basic Biological Sciences
Department of Biology
Plant Lab, Box 355325, University of Washington, Seattle, WA 98195
(206)616-1796 (voice) (206)685-4850 (lab) (206)685-1728 (FAX)
toby@u.washington.edu (email)


My general area of research interest is the genetic basis of adaptive trait evolution in natural populations.  I use a combination of laboratory, greenhouse, and field experiments to study adaptation, mostly in plants.  My background and training is primarily in molecular biology, but I have a lifelong interest in organismal biology.  I collaborate with ecologists, physiologists, and evolutionary biologists in many of my research projects.

My online calendar of appointments

People in my lab

Current Research Projects

To get a fuller picture of my research, PowerPoint files of one or two recent research seminars can be downloaded under the 'Seminars' heading below.

Teaching


Biographical information

Employment

Washington Research Foundation Professor of Basic Biological Sciences, UW, 2005-7
Professor, Department of Biology, University of Washington, 2003-
Research Associate Professor, College of Forest Resources, University of Washington, 1995-2003
Research Associate Professor (adjunct), Botany Department, Univ. of Washington 1995-
Research Assistant Professor, College of Forest Resources, Univ. of Washington, 1994-5
Research Assistant Professor, Dept. of Biochemistry, Univ. of Washington, 1989-94
Helen Hay Whitney Postdoctoral Fellow (Milton P. Gordon, research director), 1984-87
National Science Foundation Graduate Fellow, 1980-83
American Heart Association/Louisiana Graduate Fellow, 1980-81
Graduate assistant, LSUMC (William C. Claycomb, research director), 1979-80

Recent professional activities

Associate Chair and Graduate Program Coordinator, Department of Biology (2003- )

Search committee member for Dean of College of Arts & Sciences (2007)

Search committee member for Chair of Psychology (2005)

Search committee member for Dean of UW Graduate School and Vice Provost (2004)

Member, NIH Genetic Variation and Evolution Study Section (2004-2009)
Member, NSF Population Biology Review Panel (1998, 2002)

Participant, National Academy of Sciences Workshop on the Plant Genome Initiative (2002)

Co-organizer (with David Neale), Forest Tree Genome Workshop, San Diego (1997-2002)
Member, NASULGC Ecoterrorism Task Force (2002-2003)

Education

University of Washington, Seattle, Postdoctoral Fellow, 1984-89
Louisiana State University Medical Center, New Orleans, Graduate Fellow, 1979-84; Ph.D. Biochemistry 1984
East Carolina University, Greenville, 1978-79, B.S. Biology 1979
North Carolina State University, Raleigh, 1975-77

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Publications

All publications for the past 5 years, plus a few other key publications.

Bradshaw, H.D., Jr. (2005) Mutations in CAX1 produce phenotypes characteristic of plants tolerant to serpentine soils.  New Phytologist 167: 81-88.

Brady, K.U, Kruckeberg, A.R., & Bradshaw, H.D., Jr. (2005) Evolutionary ecology of plant adaptation to serpentine soils.  Annual Review of Ecology, Evolution, and Systematics 36: 243-266.

Strauss, S.H. & Bradshaw, H.D., Jr., eds. (2004) The bioengineered forest: Challenges for science and society. Resources for the Future Press, Washington, D.C. ISBN 1-891853-71-6.

Bradshaw, H.D., Jr. and Schemske, D.W. (2003) Allele substitution at a flower colour locus produces a pollinator shift in monkeyflowers.  Nature 426: 176-178.

Ramsey, J. R., Bradshaw, H. D., Jr., & Schemske, D. W. (2003) Components of reproductive isolation in the monkeyflowers Mimulus lewisii and M. cardinalis (Phrymaceae).  Evolution 57(7): 1520-1534.

Stirling, B., Yang, Z.K., Gunter, L.E., Tuskan, G.A., & Bradshaw, H.D., Jr. (2003) Comparative sequence analysis between orthologous regions of the Arabidopsis and Populus genomes reveals substantial synteny and collinearity.  Canadian Journal of Forest Research 33(11): 2245-2251.

Ferris, R., Long, L., Bunn, S.M., Robinson, K.M., Bradshaw, H.D., & Taylor, G. (2002) Leaf stomatal and epidermal cell development: identification of putative quantitative trait loci in relation to elevated carbon dioxide concentration in poplar.  Tree Physiology 22: 633-640.

Bradshaw, H.D., Jr. and Strauss, S.H. (2001) Plotting a course for GM forestry.  Nature Biotechnology 19(12): 1103-1104.

Stirling, B., Newcombe, G., Vrebalov, J., Bosdet, I., & Bradshaw, H.D., Jr. (2001) Suppressed recombination around the MXC3 locus, a major gene for resistance to poplar leaf rust.  Theoretical and Applied Genetics 103(8): 1129-1137.

Newcombe, G., Stirling, B., and Bradshaw, H.D., Jr. (2001) Abundant pathogenic variation in the new hybrid rust population of Melampsora xcolumbiana on hybrid poplar.  Phytopathology 91: 981-985.

Bradshaw, H.D., Jr. and Schemske, D.W. (2001) The birds and the bees of plant evolution.  Northwest Science and Technology Spring 2001: 44-49.

Bradshaw, H.D., Jr., Ceulemans, R., Davis, J., and Stettler, R.F. (2000) Emerging model systems: Poplar (Populus) as a model forest tree.  Journal of Plant Growth Regulators 19(3): 306-313.

Bradshaw, H.D., Jr. and Strauss, S.H. (2000) Breeding strategies for the 21st Century: Domestication of poplar.  Proceedings of the International Poplar Council Meeting, Portland, OR, September (in press).

Frewen, B.E., Chen, T.H.H., Howe, G., Davis, J., Rohde, A., Boerjan, W., & Bradshaw, H.D., Jr. (2000) QTL and candidate gene mapping of bud set and bud flush in Populus. Genetics 154: 837-845.

Newcombe, G, Stirling, B., McDonald, S., and Bradshaw, H.D., Jr. (2000) Melampsora xcolumbiana, a natural hybrid of M. medusae and M. occidentalis.  Mycological Research 104(3): 261-274.

Schemske, D.W. & Bradshaw, H.D., Jr. (1999) Pollinator preference and the evolution of floral traits in monkeyflowers (Mimulus). Proceedings of the National Academy of Sciences USA 96(21): 11910-11915.

Howe, G.T., Davis, J., Jeknic, Z., Chen, T.H.H., Frewen, B., Bradshaw, H.D., Jr., & Saruul, P. (1999) Physiological and genetic approaches to studying endodormancy-related traits in Populus. HortScience 34(7): 1174-1184.

Bradshaw, H.D., Jr., Otto, K.G., Frewen, B.E., McKay, J.K. & Schemske, D.W. (1998) Quantitative trait loci affecting differences in floral morphology between two species of monkeyflower (Mimulus). Genetics 149: 367-382.

Bradshaw, H.D., Jr. (1998) Case history in genetics of long-lived plants: Molecular approaches to domestication of a fast-growing forest tree: Populus. In: Molecular dissection of complex traits. Paterson, A. (ed), CRC Press, Boca Raton, Florida, pp. 219-228.

Wu, R., Bradshaw, H.D., Jr., & Stettler, R.F. (1998) Developmental quantitative genetics of growth in Populus. Theoretical and Applied Genetics 97: 1110-1119.

Wilbert, S.M., Schemske, D.W., & Bradshaw, H.D., Jr. (1997) Floral anthocyanins from two monkeyflower species with different pollinators. Biochemical Systematics and Ecology 25(5): 437-443.

Wu, R., Bradshaw, H.D., Jr., & Stettler, R.F. (1997) Molecular genetics of growth and development in Populus. V. Mapping quantitative trait loci affecting leaf variation. American Journal of Botany 84(2): 143-153.

Newcombe, G. & Bradshaw, H.D., Jr. (1996) Quantitative trait loci conferring resistance in hybrid poplar to leaf spot caused by Septoria populicola. Canadian Journal of Forest Research 26(11): 1943-1950.

Bradshaw, H.D., Jr. (1996) Molecular genetics of Populus. In: Biology of Populus and its implications for management and conservation. Stettler, R.F., Bradshaw, H.D., Jr., Heilman, P.E., & Hinckley, T.M. (eds), NRC Press, Ottawa, pp. 183-199.

Villar, M., Lefevre, F., Bradshaw, H.D., & Teissier du Cros, E. (1996) Molecular genetics of rust resistance in poplars (Melampsora larici-populina Kleb./Populus sp.) by bulked segregant analysis in a 2 x 2 factorial mating design. Genetics 143: 531-536.

Newcombe, G., Bradshaw, H.D., Jr., Chastagner, G.A., & Stettler, R.F. (1996) A major gene for resistance to Melampsora medusae f.sp. deltoidae in a hybrid poplar pedigree. Phytopathology 86(1): 87-94.

Bradshaw, H.D., Jr., Wilbert, S.M., Otto, K.G., & Schemske, D.W. (1995) Genetic mapping of floral traits associated with reproductive isolation in monkeyflowers (Mimulus). Nature 376: 762-765.

Bradshaw, H.D., Jr. & Stettler, R.F. (1995) Molecular genetics of growth and development in Populus. IV. Mapping QTLs with large effects on growth, form, and phenology traits in a forest tree. Genetics 139: 963-973.

Bradshaw, H.D., Jr., Villar, M., Watson, B.D., Otto, K.G., Stewart, S., & Stettler, R.F. (1994) Molecular genetics of growth and development in Populus. III. A genetic linkage map of a hybrid poplar composed of RFLP, STS, and RAPD markers. Theoretical and Applied Genetics 89(5): 167-178.

Bradshaw, H.D., Jr. & Coulson, T.D. (1988) Male-biased sex ratio in captive-bred Harris' Hawks. Journal of Raptor Research 22: 116-117.

Bradshaw, H.D., Jr. (1983) Molecular cloning and cell cycle-specific regulation of a functional human thymidine kinase gene. Proceedings of the National Academy of Sciences USA 80: 5588-5591.

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Seminars

Past 5 years only.  NB: Links are to PowerPoint presentations, some of them quite large (up to 5MB -- can be awfully slow over a phone line!).

Bradshaw, H.D., Jr. (2007) The genetics of adaptation and speciation in monkeyflowers (Mimulus).  University of Toronto, Toronto ON, 9 February.

Bradshaw, H.D., Jr. (2007) Genetically engineered plants: The science behind the controversy.  Science and Technology Roundtable, Spokane Athletic Club, Spokane WA, 2 February.

Bradshaw, H.D., Jr. (2007) The genetics of adaptation and speciation in monkeyflowers (Mimulus).  University of Wisconsin, Madison WI, 25 January.

Bradshaw, H.D., Jr. (2007) The genetics of adaptation and speciation in monkeyflowers (Mimulus).  University of British Columbia, Vancouver BC, 16 January.

Bradshaw, H.D., Jr. (2006) The genetics of adaptation and speciation in monkeyflowers (Mimulus).  Purdue University, West Lafayette IN, 29 November.

 Bradshaw, H.D., Jr. (2006) The genetics of adaptation and speciation in Mimulus and its hybrids.  Gordon Conference, Ventura CA, 5-10 February.

Bradshaw, H.D., Jr. (2006) Genetically engineered plants: The science behind the controversy.  Science and Technology Roundtable, Rainier Club, Seattle WA, 13 January.

Bradshaw, H.D., Jr. (2005) Genetics of adaptation in natural plant populations.  Ecological Genomics Symposium, Lenexa KS, 4-6 November.

Bradshaw, H.D., Jr. (2005) Genetics of adaptation in natural plant populations.  Oregon State University, Corvallis, OR, 19 May (invited by graduate students).

Bradshaw, H.D., Jr. (2005) Genetically engineered plants: The science behind the controversy.  UW Science Forum, University of Washington, Seattle WA , 14 April.

Bradshaw, H.D., Jr. (2005) Genetics of adaptation in natural plant populations.  University of California, Davis CA , 14 March.

Bradshaw, H.D., Jr. (2005) Genetics of adaptation in natural plant populations.  University of Victoria, Victoria BC, 28 January.

Bradshaw, H.D., Jr. (2004) Genetics of adaptation in natural plant populations.  Keynote speaker at Annual Plant Center Symposium, University of Georgia, Athens GA, 10 March.

Bradshaw, H.D., Jr. (2004) Genetics of adaptation in natural plant populations.  Harvard University, Cambridge MA, 30 April.

Bradshaw, H.D., Jr. (2004) Genetics of plant adaptation to serpentine soils.  University of Nebraska, Lincoln NB, 6 Feb.

Bradshaw, H.D., Jr. (2004) The origin of plant species.  University of Nebraska, Lincoln NB, 5 Feb.

Bradshaw, H.D., Jr. (2003) Genetics of adaptation in natural plant populations. University of Alaska, Fairbanks AK  14-17 March.

Bradshaw, H.D., Jr. and Schemske, D.W. (2002) Genetics of adaptation in natural plant populations.  Molecular genetics and ecology of adaptation.  UBC Botanical Garden, Vancouver B.C.,  11-13 December.

Bradshaw, H.D., Jr. & Gordon, M.P. (2002) Genetically engineered organisms in Europe and the U.S. World Affairs Council Meeting, Seattle WA, 27 June.

Bradshaw, H.D., Jr. (2002) Comparative genomics of adaptive evolution. National Academy of Sciences Committee on the National Plant Genome Inititative, Washington, D.C., 6 June.

Bradshaw, H.D., Jr. (2002) Terrorism in the debate over genetic research. Washington Native Plant Society, Seattle WA, 7 February.

Bradshaw, H.D., Jr. (2002) The poplar genome project. Department of Energy contractor’s meeting, Oakland CA, 29 January.

Bradshaw, H.D., Jr. (2002) Terrorism in the debate over tree genetic improvement. Emerald City Rotary Club, Seattle WA, 8 January.


Last revised: 17-Mar-2007