AKILESH Lab at the University of Washington
Copyright 2023 Shreeram Akilesh.
Integrative Genome Browser
We provide a stable UCSC Genome Browser instance to conveniently view our own epigenomic data sets (ATAC-seq, RNA-seq, Hi-C) as well as orthogonal published datasets such as snATAC-seq, GWAS and ENCODE ChIP-seq data. Our previously published datasets are also available through this browser for comparison. The screencap below shows how these different views of the genome inform our understanding of the UMOD locus. You can even load your own data into the instance as custom tracks. Click the link below the schematic to go to our recommended browser session. For those who want to link to the track hub directly, the URL is here.
Datasets that have been incorporated into this browser instance include:
- Multi-omic Analysis of Primary Human Kidney Tissues Identifies Medulla-Specific Gene Expression Patterns
- Serum Protein Exposure Activates a Core Regulatory Program Driving Human Proximal Tubule Injury
- Integrated Functional Genomic Analysis Enables Annotation of Kidney Genome-Wide Association Study Loci
Single-nucleus ATAC-seq data and cis-coaccessibility networks
- Single cell transcriptional and chromatin accessibility profiling redefine cellular heterogeneity in the adult human kidney
Kidney genome-wide association studies (GWAS)
- Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria
- A catalog of genetic loci associated with kidney function from analyses of a million individuals
Chromatin immunoprecipitation and sequencing (ChIP-seq)
- ENCODE Project ChIP-seq from adult human kidney
Functional genomics datasets generated by our laboratory
