Recent publications by members of the group:
- Baggett D.W., Nath A.* (2018) "The Rational Discovery of a Tau Aggregation Inhibitor."
Biochemistry 57(42):6099-6107. »
- Goulet D.R., Watson M.J., Tam S.H., Zwolak A., Chiu M.L., Atkins W.M.,* Nath A.* (2018) "Towards a Combinatorial Approach for the Prediction of Immunoglobulin G Half-Life and Clearance." Drug Metab. Dispos. 46(12):1900-1907. »
- Zhong G, Ortiz DJ, Zelter A, Nath A, Isoherranen N (2018) "CYP26C1 is a hydroxylase of multiple active retinoids and interacts with cellular retinoic acid binding proteins."
Mol. Pharm. 93(5):489-503.
- Baughman HER, Clouser AF, Klevit RE,* Nath A.* (2018) "HspB1 and Hsc70 chaperones engage distinct tau species and have different inhibitory effects on amyloid formation." J. Biol. Chem. 293(8):2687-2700. »
- Lockhart CO, Smith TB, Yang P, Naidu M, Rettie AE, Nath A, Weleber R, Kelly EJ. (2018) "Longitudinal characterization of function and structure of Bietti crystalline dystrophy: Report on a novel homozygous mutation in CYP4V2." Br. J. Ophthalmol. 102(2):187-94. »
- Ferrie JJ, Haney CM, Yoon J, Pan B, Lin Y, Fakhraai Z, Rhoades E, Nath A, Petersson EJ. (2017) "Using a large ensemble FRET library with multiple probe pairs to drive Monte Carlo simulations of disordered α-synuclein." Biophys. J. 114(1):53-64. »
- McDonald MG, Ray S, Amorosi CJ, Sitko KA, Kowalski JP, Paco L, Nath A, Gallis BM, Totah RA, Dunham MJ, Fowler DM, Rettie AE. (2017) "Expression and functional characterization of breast cancer-associated cytochrome P450 4Z1 in Saccharomyces cerevisiae." Drug Metab Dispos. 45(12):1364-71. »
- Li MJ, Nath A, Atkins WM. (2017) "Differential coupling of binding, ATP hydrolysis, and transport of fluorescent probes with P-glycoprotein in lipid nanodiscs." Biochemistry 56(19):2506-17. »
- Goulet DR, Zwolak A, Chiu ML, Nath A, Atkins WM. (2017) "Diffusion of soluble aggregates of THIOMABs and bispecific antibodies in serum." Biochemistry 56(17):2251-60 »
- Nakatani-Webster E, Nath A. (2017) Inferring mechanistic parameters from amyloid formation kinetics by approximate Bayesian computation. Biophys J 112(5):868-80 »
- Melo AM, Coraor J, Alpha-Cobb G, Elbaum-Garfinkle E, Nath A, Rhoades E. (2016) A functional role for intrinsic disorder in the tau-tubulin complex. PNAS 113(50):14336-41 »
- Sager J, Tripathy S, Price LS, Nath A, Chang J, Stephenson-Famy A, Isoherranen N. (2016) In vitro to in vivo extrapolation of the complex drug-drug interaction of buproprion and its metabolites with CYP2D6: simultaneous reversible inhibition and CYP2D6 downregulation. Biochem. Pharmacol. 123:85-96 »
- Booth A, Vane EW, Dovala D, Thorner J. (2015) A Förster resonance energy transfer (FRET)-based system provides insight into the ordered assembly of yeast septin hetero-octamers. J Biol Chem. 290:28388-401 »
- Nath A, Schlamadinger DE, Rhoades E, Miranker AD. (2015) Structure-based small molecule modulation of a pre-amyloid state: pharmacological enhancement of IAPP membrane-binding and toxicity. Biochemistry 54(22):3555-64. »
- Hernando-Pérez M, Lambert S, Nakatani-Webster E, Catalano CE, de Pablo PJ. (2014) "Cementing proteins provide extra mechanical stabilization to viral cages." Nat Commun. 5:4520. »
- Kumar S, Brown MA, Nath A, Miranker AD. (2014) "Folded small molecule manipulation of islet amyloid polypeptide." Chem Biol. 21(6):775-81. »
- Munro JB, Nath A, Färber M, Datta SA, Rein A, Rhoades E, Mothes W. (2014) "A conformational transition observed in single HIV-1 Gag molecules during in vitro assembly of virus-like particles." J Virol. 88(6):3577-85. »
- Singh P†, Nakatani E†, Goodlett DR, Catalano CE. (2013) "A pseudo-atomic model for the capsid shell of bacteriophage lambda using chemical cross-linking/mass spectrometry and molecular modeling." J Mol Biol. 425(18):3378-88. »
- Lin Y, Watson KA, Kim JW, Baggett DW, Working DC, Connell JW. (2013) "Bulk preparation of holey graphene via controlled catalytic oxidation." Nanoscale. 5(17):7814-24. »
- Nath A, Rhoades E. (2013) "A flash in the pan: dissecting dynamic amyloid intermediates using fluorescence." FEBS Lett. 587(8):1096-105. »
† indicates authors contributed equally.
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