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Publications

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84. Kim H, Hong F, Mollica MY, Golla K, De Silva E, Sniadecki NJ, Lopez JA. Filamin A regulates platelet shape change and contractile force generation via phosphorylation of the myosin light chain. Biochem J. 2024. doi: 10.1042/BCJ20240114. [PUBMED]

83. Mulimani P, Mazzawi NA, Goldstein AJ, Obenaus AM, Baggett SM, Troung D, Popowics TE, Sniadecki NJ. Engineered 3D Periodontal Ligament Model with Magnetic Tensile Loading. J Dent Res. 2024. doi: 110.1177/00220345241264792. [PUBMED]

82. Goldstein AJ, Padgett RM, Bremner SB, Higashi T, Obenaus AM, Bolduan S, Mack DL, Sniadecki NJ. Engineered Heart Tissues for Standard 96-Well Tissue Culture Plates. Methods Mol Biol. 2024;2805:89-100. doi: 10.1007/978-1-0716-3854-5_5. [PUBMED]

81. Gurkan UA, Wood DK, Carranza D, Herbertson LH, Diamond SL, Du E, Guha S, Di Paola J, Hines PC, Papautsky I, Shevkoplyas SS, Sniadecki NJ, Pamula VK, Sundd P, Rizwan A, Qasba P, Lam WA. (2024) Next generation microfluidics: fulfilling the promise of lab-on-a-chip technologies. Lab Chip. Mar 26;24(7):1867-1874. doi: 10.1039/d3lc00796k. PMC10964744. [PUBMED]

80. Stratiievska A, Filippova O, Öpolat T, Byrne D, Bailey SL, Chauhan A, Mollica MY, Harris J, Esancy K, Chen J, Dhaka AK, Sniadecki NJ, López JA, Stolla M. (2024) Cold Temperature Induces a TRPM8-independent Calcium Release from the Endoplasmic Reticulum in Human Platelets. PLoS One. Mar 4;19(3):e0289395. doi: 10.1371/journal.pone.0289395. PMC10911599. [PUBMED]

79. Mollica M, Beussman KM, Kandasamy A, Rodriguez LM, Morales FR, Chen J, Manohar K, del Álamo JC, López JA, Thomas WE, Sniadecki NJ, Distinct Platelet F-Actin Patterns and Traction Forces on von Willebrand Factor versus Fibrinogen. (2023) Distinct Platelet F-Actin Patterns and Traction Forces on von Willebrand Factor versus Fibrinogen. Biophys J. Sep 19;122(18):3738-3748. doi: 10.1016/j.bpj.2023.07.006. [PUBMED]

78. Marchiano S, Nakamura K, Reinecke H, Neidig L, Lai M, Kadota S, Perbellini F, Yang X, Klaiman JM, Blakely LP, Karbassi E, Fields PA, Fenix AM, Beussman KM, Jayabalu A, Kalucki FA, Futakuchi-Tsuchida A, Weber GJ, Dupras S, Tsuchida H, Pabon L, Wang L, Knollmann BC, Kattman S, Thies RS, Sniadecki NJ, MacLellan WR, Bertero A, Murry CE. (2023). Gene Editing to Prevent Ventricular Arrhythmias Associated with Cardiomyocyte Cell Therapy. Cell Stem Cell. Apr 6;30(4):396-414.e9. PMC10283080. [PUBMED]

77. Loiben AM, Chien WM, Friedman CE, Chao LS, Weber G, Goldstein A, Sniadecki NJ, Murry CE, Yang KC (2023) Cardiomyocyte Apoptosis Is Associated with Contractile Dysfunction in Stem Cell Model of MYH7 E848G Hypertrophic Cardiomyopathy. Int J Mol Sci. Mar 3;24(5):4909. PMC10003263. [PUBMED]

76. Smith A.S., Luttrell S.M., Dupont J.B., Gray K., Lih D., Fleming J.W., Cunningham N.J., Jepson S., Hesson J., Mathieu J., Maves L., Berry B.J., Fisher E.C., Sniadecki N.J., Geisse N.A., Mack D.L. (2022) High-Throughput, Real-Time Monitoring of Engineered Skeletal Muscle Function Using Magnetic Sensing J Tissue Eng.. Sep 2;13:20417314221122127. doi: 10.1177/20417314221122127 [PUBMED]

75. Bremner S.B, Mandrycky, C.J., Leonard, A., Padgett, R.M., Levinson, A.R., Rehn, E.S., Pioner, J.M., Sniadecki N.J., Mack, D.L. (2022) Full-length Dystrophin Deficiency Leads to Contractile and Calcium Transient Defects in Human Engineered Heart Tissue. J Tissue Eng.. Aug 17;13:20417314221119628 [PUBMED]

74. Mair D.B., Williams M.A.C., Chen J.F., Goldstein A., Wu A., Lee P.H.U., Sniadecki N.J., Kim D.H. (2022) PDMS-PEG Block Copolymer and Pretreatment for Arresting Drug Absorption in Microphysiological Devices. ACS Appl Mater Interfaces.. 14(34):38541-38549. doi: 10.1021/acsami.2c10669. [PUBMED]

73. Katiyar A., Zhang J., Antani J.D., Yu Y., Scott K.L., Lele P.P., Reinhart-King C.A., Sniadecki N.J., Roux K.J., Dickinson R.B., Lele T.P. (2022) The Nucleus Bypasses Obstacles by Deforming Like a Drop with Surface Tension Mediated by Lamin A/C. Advanced Science. Jun 16:e2201248. doi: 10.1002/advs.202201248. [PUBMED]

72. Bremner S., Goldstein, A.J., Higashi, T., Sniadecki N.J. (2022) Engineered Heat Tissues for Contractile, Structural, and Transcriptional Assessment of Human Pluripotent Stem Cell-Derived Cardiomyocytes in a Three-Dimensional, Auxotonic Environment. Methods in Molecular Biology. Chapter 6: 87-97. doi: 10.1007/978-1-0716-2261-2_6. [PUBMED]

71. Hardin, W.R., Alas, G.C.M., Taparia, N., Thomas, E.B., Steele-Ogus, M., Hvorecny, K.L, Halpern, A., Tumova, P., Kollman, J., Vaughan, J., Sniadecki, N.J., Paredez, A.R. (2022) The Giardia ventrolateral flange is a lamellar membrane protrusion that supports attachment. PLoS Pathogens Apr 28;18(4):e1010496 [PUBMED]
70. Steele-Ogus MC, Obenaus AM, Sniadecki NJ, Paredez AR. (2022) Disc and Actin Associated Protein 1 influences attachment in the intestinal parasite Giardia lamblia. PLoS Pathogens. Mar 25;18(3):e1010433. [PUBMED]
69. Bremner S.B., Gaffney K.S., Sniadecki N.J., Mack D.L. (2022) A Change of Heart: Human Cardiac Tissue Engineering as a Platform for Drug Development. Current Cardiology Reports. Mar 5:1-14. PMC8897733 [PUBMED]
68. Falconieri, A.*, Taparia, N.*, De Vincentiis, S.*, Cappello V., Sniadecki, N.J., Raffa, V. (2022) Magnetically-Actuated Microposts Stimulate Axon Growth. Biophysical Journal 121(3):374-382. PMC8822606 [PUBMED]
67. Beussman, K.M.*, Mollica, M.Y.*, Leonard, A., Miles, J., Hocter, J., Song, Z., Stolla, M., Han, S.J., Emery, A., Thomas, W.E., Sniadecki, N.J. (2021) Black Dots: Microcontact-Printed, Reference-Free Traction Force Microscopy. Acta Biomateriala. Nov 13:S1742-7061(21)00754-6. [PUBMED]
66. Fenix, A.M.*, Miyaoka, Y.*, Bertero, A., Spindler, M.J., Tan, K.K.B., Perez-Bermejo, J., Chan, A.H., Mayer, S.J., Nguyen, T., Russell, C.R., Lizarraga, P., Truong, A., So, P.-L., Kulkarni, A., Chetal, K., Sathe, S, Sniadecki, N.J., Yeo, G.W., Murry, C.E., Conklin, B.R., Salomonis, N. (2021) Gain-of-function pathogenic mutations in RBM20 rewire splicing regulation and re-distribute ribonucleoprotein aggregates within processing bodies. Nature Communications. Nov 3;12(1):6324. PMC8679671 [PUBMED]
65. Miles, J., Bailey, S.L., Obenaus, A.M., Mollica, M.Y., Usaneerungrueng, C., Byrne, D.A., Fang, L., Flynn, J.R., Corson, J., Osborne, B., Houck, K.L., Wang, Y., Shen, Y., Fu, X., Dong, J.F., Sniadecki, N.J., Stolla, M. (2021) Storage temperature determines platelet GPVI levels and function in mice and humans. Blood Advances. Oct 12;5(19):3839-3849. PMC8679671 [PUBMED]
64. El-Nachef, D., Bugg, D, Beussman, K.M., Steczina, S., Martinson, A.M., Murry, C.E., Sniadecki, N.J., Davis, J. (2021) Engrafted Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Undergo Clonal Expansion In Vivo. Circulation. 43(16):1635-1638. PMC8059012. [PUBMED]
63. Tsui, J.H., Leonard, A., Camp, N.D., Long, J.T., Nawas, Z.Y., Chavanachat, R., Smith, A.S.T., Choi, J.S., Dong, Z., Ahn, E.H., Wolf-Yadlin, A., Murry, C.E., Sniadecki, N.J., Kim, D.-H. (2021) Tunable Electroconductive Decellularized Extracellular Matrix Hydrogels for Engineering Human Cardiac Microphysiological Systems. Biomaterials. 272:120764. PMC8074529. [PUBMED]
62. Marchiano, S., Hsiang, T.Y., Khanna, A., Higashi, T., Whitmore, L.S., Bargehr, J., Davaapil, H., Chang, J., Smith, E., Ong, L.P., Colzani, M., Reinecke, H., Yang, X., Pabon, L., Sinha, S., Najafian, B., Sniadecki. N.J., Bertero, A., Gale, M. Jr., Murry, C.E. (2020) SARS-CoV-2 Infects Human Pluripotent Stem Cell-Derived Cardiomyocytes, Impairing Electrical and Mechanical Function. Stem Cell Reports. 16(3):478-492. PMC7881699. [PUBMED]
61. Mandrycky, C.J., Williams, N.P., Batalov, I., El-Nachef, D., de Bakker, B.S., Davis, J., Kim D.-K., DeForest, C.A., Zheng, Y., Stevens, K.R., Sniadecki, N.J. (2020) Engineering Heart Morphogenesis. Trends in Biotechnology. 38(8):835-845. PMC7368094 [PUBMED]
60. El-Nachef, D., Shi, K., Beussman, K.M., Martinez, R., Regier, M.C., Everett, G.W., Murry, C.E., Stevens, K.R., Young, J.E., Sniadecki, N.J., Davis, J. (2020) A Rainbow Reporter Tracks Single Cells and Reveals Heterogeneous Cellular Dynamics among Pluripotent Stem Cells and Their Differentiated Derivatives. Stem Cell Reports. 43(16):1635-1638 [PDF] [SUP MAT]

59. Mandrycky, C.J., Williams, N.P., Batalov, I., El-Nachef, D., de Bakker, B.S., Davis, J., Kim D.-K., DeForest, C.A., Zheng, Y., Stevens, K.R., Sniadecki, N.J. (2020) Engineering Heart Morphogenesis. Trends in Biotechnology. doi: 10.1016/j.tibtech.2020.01.006. [PDF]

58. Obenaus, A.M., Mollica, M.Y., Sniadecki, N.J. (2020) (De)form and Function: Measuring Cellular Forces with Deformable Materials annd Deformable Structures. Advances Healthcare Materials. doi: 10.1002/adhm.201901454. [PDF]

57. Miklas, J.W., Clark, E., Levy, S., Detraux, D., Leonard, A., Beussman, K., Showalter, M., Smith, A.T., Hofsteen, P., Yang, X., Macadangdang, J., Manninenk, T., Raftery, D., Madan, A., Suomalainen, A., Kim, D.H., Murry, C.E., Feihn, O., Sniadecki, N.J., Yang, Y., Ruohola-Baker H. (2019) The human disease gene TFPa/HADHA is required for fatty acid beta-oxidation and cardiolipin re-modeling in human cardiomyocytes. Nature Communications. 2019 Oct 11;10(1):4671. doi: 10.1038/s41467-019-12482-1. [PDF]

56. Zaunbrecher, R.J., Abel, A., Beussman, B., Leonard, A., von Frieling-Salewsky, M., Fields, P., Pabon, L., Reinecke, H., Yang, X., Macadangdang, J., Kim, D.H., Linke, W.A., Sniadecki, N.J., Regnier, M., Murry, C.E. (2019) Cronos Titin is Expressed in Human Cardiomyocytes and Necessary for Normal Sarcomere Formation. Circulation. https://doi.org/10.1161/CIRCULATIONAHA.119.039521 [PDF]

55. Yang, X., Rodriguez, M.L., Leonard, A., Sun, L., Fischer, K.A., Wang, Y., Ritterhoff, J., Zhao, L., Kolwicz, S.C., Pabon, L., Reinecke, H., Sniadecki, N.J., Tain, R., Ruohola-Baker, H., Xu, H., Murry, C.E. (2019) Fatty Acids Enhance the Maturation of Cardiomyocytes Derived from Human Pluripotent Stem Cells. Stem Cell Reports.  https://doi.org/10.1016/j.stemcr.2019.08.013  [PDF]

54. Bertero, A., Fields, P.A., Smith, A.S.T., Leonard, A., Beussman, K., Sniadecki, N.J., Kim, D.H., Tse H.F., Pabon, L., Shendure, J., Noble, W.S., Murry, C.E. (2019) Chromatin compartment dynamics in a haploinsufficient model of cardiac laminopathy. J Cell Biol.  doi: 10.1083/jcb.201902117  [PDF]

53. Manifacier, I., Beussman, K.M., Han, S.J., Sniadecki, N.J., About, I., Milan, J.L. (2019) The Consequence of Substrates of Large-scale Rigidity on Actin Network Tension in Adherent Cells. Comp Meth Biomech Biomed Eng.  doi: 10.1080/19336918.2019.1568140  [PDF]

52. Ting, L.H., Feghhi, S., Taparia, N., Smith, A.O., Karchin, A., Lim, E., St. John, A., Wang, X., Rue, T., White, N.J., Sniadecki, N.J. (2019) Contractile Forces in Platelet Aggregates Under Microfluidic Shear Gradients Reflect Platelet Inhibition and Bleeding Risk. Nature Communications.  10:1204 [PDF] [SUP MAT]

51. Rodriguez, M.L., Beussman, K. M., Chun, K.S., Walzer, M.S., Yang, X., Murry, C.E., Sniadecki, N.J. (2019) Substrate Stiffness, Cell Anisotropy, and Cell‐Cell Contact Contribute to Enhanced Structural and Calcium Handling Properties of Human Embryonic Stem-Cell-Derived Cardiomyocytes. ACS Biomat Sci Engr.  doi:10.1021/acsbiomaterials.8b01256 [PDF]

50. Al-Rekabi, Z., Fura, A.M., Juhlin, I., Yassin, A., Popowicz, T.E, Sniadecki, N.J. (2019) Hyaluronan-CD44 interactions mediate contractility and migration in periodontal ligament cells. Cell Adhesion & Migration..  13(1):138-150 [PDF]

49. Chi C., Leonard, A., Knight, W.E., Beussman, K.M., Zhao, Y., Cao, Y., Londono, P., Aune, E., Trembley, M.A., Small, E.M., Jeong, M.Y., Walker, L.A., Xu, H., Sniadecki, N.J., Taylor, M.R., Buttrick, P.M., Song, K. (2018) LAMP-2B regulates human cardiomyocyte function by mediating autophagosome-lysosome fusion. Proc Nat Acad Sci..  116(2):556-565 [PDF] [SUP MAT]

48. Leonard A., Bertero A., Powers J.D., Beussman K.M., Bhandari S., Regnier M., Murry C.E., Sniadecki N.J. (2018) Afterload promotes maturation of human induced pluripotent stem cell derived cardiomyocytes in engineered heart tissues. J Mol Cell Cardiol.  118:147-158. [PDF] [SUP MAT]

47. Taparia, N., Platten, K.C., Anderson, K.B., Sniadecki, N.J. (2017) A Microfluidic Approach For Hemoglobin Detection in Whole Blood. AIP Advances.  7, 105102 [PDF] [SUP MAT]

46. Broussard, J.A., Yang, R., Huang, C., Nathamgari, S.S.P., Beese, A.M., Godsel, L.M., Hegazy, M.H., Lee, S., Zhou, F., Sniadecki, N.J., Green, K.J., Espinosa, H.D. (2017) The Desmoplakin/Intermediate Filament Linkage Regulates Cell Mechanics. Mol Biol Cell.  28(23):3156-3164 [PDF]

45. Al-Rekabi, Z., Cunningham, M.L., Sniadecki, N.J. (2017) Cell Mechanics in Craniosynostosis. ACS Biomat Sci Engr.  3 (11):2733-2743 [PDF]

44. Bielawski, K.B., Leonard, A., Bhandari, S., Murry, C.E., Sniadecki, N.J. (2016) Real-Time Force and Frequency Analysis of Engineered Heart Tissues Derived from Induced Pluripotent Stem Cells Using Magnetic Sensing. Tissue Eng Part C Methods.  22(10): 932-940. [PDF]

43. Han, S.J., Rodriguez, M.L., Al-Rekabi, Z., Sniadecki, N.J. (2016) Mechanics and Modeling of One-Dimensional Cell Migration. Cell Adhesion & Migration.  10(5): 529-539. [PDF][SUP MAT]

42. Feghhi, S., Tooley, W.W., Sniadecki, N.J. (2016) Nonmuscle Myosin IIA Regulates Platelet Contractile Forces Through Rho Kinase and Myosin Light-Chain Kinase. J Biomechanical Engineering.  138, 104506 [PDF]

41. Feghhi, S., Munday, A.D., Tooley, W.W., Rajsekar, S. Fura, A.M., Kulman, J.D., López, J.A., Sniadecki, N.J. (2016) Glycoprotein Ib-IX-V Complex Transmits Cytoskeletal Forces That Enhance Platelet Adhesion. Biophys J 111, 601-8 [PDF]

40. Milan, J.L., Manifacier, I., Beussman, K.M., Han, S.J., Sniadecki, N.J., About, I., Chabrand, P. (2016) In silico CDM Model Sheds Light on Force Transmission in Cell from Focal Adhesions to Nucleus. J Biomechanics 49(13):2625-2634 [PDF]

39. Al-Rekabi, Z., Wheeler, M.M., Leonard, A., Fura, A.M., Juhlin, I., Frazar, C., Smith, J.D., Park, S.S., Gustafson, J.A., Clarke, C.M., Cunningham, M.L., Sniadecki, N.J. (2016) Activation of IGF1 Pathway Mediates Changes in Cellular Contractility and Motility in Single-Suture Craniosynostosis. J Cell Science 129(3):483-91 [PDF]

38. Bielawski, K.S., Sniadecki, N.J. (2016) A Magnetic Micropost Approach for Measuring the Viscoelasticity of Biomaterials. J Microelectromechanical Systems 25(1):153-9 [PDF]

37. Beussman, K.M., Rodriguez, M.L., Leonard, A., Taparia, N., Thompson, C.R., Sniadecki, N.J., (2015) Micropost Arrays for Measuring Stem Cell-Derived Cardiomyocyte Contractility. Methods 94:43-50. PMID: 26344757 [PDF]

36. Leonard, A., Rodriguez, M.L., Sniadecki, N.J. (2015) Micropost Arrays as a Means to Assess Cardiac Muscle Cells. In Integrative Mechanobiology: Micro and Nano Techniques in Cell Mechanobiology (ed. Y. Sun, D.-H. Kim, C. Simmons). Cambridge Press. Chapter 16 [Link]

35. Kuppusamy, K.T., Jones, D., Sperber, H., Madan, A., Fisher, K., Rodriguez, M.L., Pabon, L. Zhu, W.Z., Tulloch, N., Yang, X., Sniadecki, N.J., Laflamme, M.A., Ruzzo, W.L., Murry, C.E., Ruohola-Baker, H. (2015) Let-7 Family of miRNA Is Required For Maturation and Adult-like Metabolism in Stem Cell-Derived Cardiomyocytes. Proc Nat Acad Sci. 112(21):E2785-94  [PDF]

34. Bielawski, K.S., Sniadecki, N.J. (2015) Micropost Methods for Cell Biomechanics of the Cardiovascular System. In Cell, Forces, and the Microenvironment (ed. A.E. Pelling and C.M. Cuerrier), Pan Stanford Publishing. Chapter 12 [Link]  [PDF]

33. Sniadecki, N.J., Chen. C.S. (2014) Measuring Cellular Traction Forces at the Micro- and Nano-scale. In Vol. 2 - Medical Devices and Systems: The Biomedical Engineering Handbook, Fourth Edition (ed. J.D. Bronzino and D.R. Peterson). CRC Press. [Link]

32. Rodriguez, M.R., Sniadecki, N.J. (2014) Computational Modeling of Cell Mechanics. In Computational Modelling of Biomechanics in the Musculoskeletal System: Tissues, Replacements and Regeneration (ed. Z. Jin), Woodhead Publishing. Chapter 4, pg. 93-140. [Link]

31. Sniadecki, N.J., Han, S.J., Ting, L.H., Feghhi, S. (2014) Micropatterning on Micropost Arrays. In Methods in Cell Biology - Micropatterning in Cell Biology. (ed. M. Piel and M. Thery), Elsevier: New York. Vol 121, Chapter 5, pg. 61-73. [PDF] 

30. Yang, X., Rodriguez, M.L., Pabon, L.M., Fischer, K.A., Reinecke, H., Regnier, M., Sniadecki, N.J., Ruohola-Baker, H., Murry, C.E.  (2014)  Tri-iodo-L-thyronine Promotes the Maturation of Cardiomyocytes-Derived from Human Induced Pluripotent Stem Cells. Journal of Molecular and Cellular Cardiology.  72:296-304. PMID: 24735830. [PDF] 

29. Rodriguez, M.L., Graham, B.T., Pabon, L.M., Han, S.J., Murry, C.E., Sniadecki, N.J.  (2014)  Measuring the Contractile Forces of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes with Arrays of Microposts. J Biomechanical Engineering.  136(5), 051005  [PDF] 

28. Rodriguez, M.L., McGarry, P.J., Sniadecki, N.J.  (2013)  Review on Cell Mechanics: Experimental and Modeling Approaches. Applied Mechanics Review.  65(6), 060801  [PDF] 

27. Rodriguez, A.G., Rodriguez, M.L., Han, S.J. Sniadecki, N.J., Regnier, M.  (2013)  Enhanced Contractility with 2-deoxy-ATP and EMD 57033 is Correlated with Reduced Myofibril Structure and Twitch Power in Neonatal Cardiomyocytes. Integr Biol.  5(11):1366-73.  [PDF] 

26. Borysiak, M.D., Bielawski, K.S., Sniadecki, N.J., Jenkel, C.F., Vogt, B.D., Posner, J.D.  (2013)  Simple Replica Micromolding of Biocompatible Styrenic Elastomers. Lab on a Chip.  13:2773-84.  [PDF] 

25. Han, S.J., Bielawski, K.S., Ting, L.H., Rodriguez, M.L., Sniadecki, N.J.  (2012)  Decoupling Substrate Stiffness, Spread Area, and Micropost Density: A Close Spatial Relationship Between Traction Forces and Focal Adhesions. Biophys J.  103(4): 640-8.  [PDF]  [SUP MAT]

24. Ting, L.H., Jahn, J.R., Jung, J.L., Shuman, B.R., Feghhi, S., Han, S.J., Rodriguez, M.L., Sniadecki, N.J.  (2012)  Flow Mechanotransduction Regulates Traction Forces, Intercellular Forces, and Adherens Junctions. Am J Physiol Heart Circ Physiol.  302: H2220-H2229.  [PDF] 

23. Ting, L.H., Feghhi, S., Han, S.J., Rodriguez, M.L., Sniadecki, N.J.  (2011)  Effect of Silanization Film Thickness in Soft Lithography of Nanoscale Features. ASME J Nano Engr Medicine.  2(4):041006.  [PDF] 

22. Feghhi, S., Sniadecki, N.J.  (2011)  Mechanobiology of Platelets: Techniques to Study the Role of Fluid Flow and Platelet Retraction Forces at the Micro- and Nano-Scale. Int J Mol Sci.  12(12):9009-30.  [PDF] 

21. Rodriguez, A.G., Han, S.J., Regnier, M., Sniadecki, N.J.  (2011)  Substrate Stiffness Increases Twitch Power of Neonatal Cardiomyocytes in Correlation with Changes in Myofibril Structure and Intracellular Calcium. Biophys J.  101(10):2455-2464.  [PDF] 

20. Ting, L.H., Sniadecki, N.J.  (2011)  Biological Micro-Electromechanical Systems (BioMEMS). In Comprehensive Biomaterials.  (eds. P. Ducheyne, K.E. Healy, D.W. Hutmacher, D.W. Grainger, and C.J. Kirkpatrick).  Elsevier: Waltham, MA.  3.15:257-276.  [PDF]  [Link]

19. Han, S.J., Sniadecki, N.J.  (2011)  Nanotechnology Usages for Cellular Adhesion and Traction Forces. In Cellular and Biomolecular Mechanics and Mechanobiology.  (ed. A. Gefen).  Springer: New York.  4:177-200.  [PDF]  [Link]

18. Han, S.J., Sniadecki, N.J.  (2011)  Simulations of the Contractile Cycle in Cell Migration Using a Bio-Chemical-Mechanical Model. Comp Meth Biomech Biomed Eng.  14(5):459-468  [PDF]

17. Tooley, W.W., Feghhi, S., Han, S.J., Wang, J., Sniadecki, N.J.  (2011)  Thermal Fracture of Oxidized Polydimethylsiloxane during Soft Lithography of Nanopost Arrays. J Microeng Micromech.  21(5):054013  [PDF]  [SUP MAT]  [Cover]

16. Raghavan, S., Shen, C.J., Desai, R.A., Sniadecki, N.J., Nelson, C.M., Chen, C.S.  (2010)  Decoupling Diffusional from Dimensional Control of Signaling in 3D Culture Reveals a Role for Myosin in Tubulogenesis. J Cell Sci.  123(17):2877-2883  [PDF]

15. Liu, Z., Tan J.L., Cohen, D., Yang, M.T., Sniadecki N.J., Alom Ruiz, S., Nelson, C.M., Chen, C.S.  (2010)  Mechanical Tugging Forces Regulates the Size of Cell-Cell Junctions.  Proc Nat Acad Sci.  107(22):9944-9  [PDF]

14. Liu, Z., Sniadecki, N.J., Chen, C.S.  (2010)  Mechanical Forces in Endothelial Cells during Firm Adhesion and Early Transmigration of Human Monocytes.  Cellular and Molecular Bioengineering.  3(1):50-9  [PDF]

13. Liang, X.M, Han, S.J., Reems, J.A., Gao, D., Sniadecki, N.J.  (2010)  Platelet Retraction Force Measurements Using Flexible Post Force Sensors.  Lab on a Chip.  10(8): 991-8  [PDF]  [Cover]

12. Sniadecki, N.J.  (2010)  A Tiny Touch: Activation of Cell Signaling Pathways with Magnetic Nanoparticles.  Endocrinoloy.  151(2):451-7  [PDF]

11. Sniadecki, N.J., Legant, W.L., Chen, C.S.  (2009)  Micro- and Nanoscale Force Techniques for Mechanotransduction.  In Cellular Mechanotransduction.  (ed. R. Kamm and M. Mofrad).  Cambridge University Press: Cambridge.  16:377-402.  [Link]

10. Sniadecki, N.J., Chen, C.S., Lamb, C.M, Liu, Y., Reich, D.H.  (2008)  Magnetic Microposts for Mechanical Stimulation of Biological Cells: Fabrication, Characterization, and Analysis.  Review of Scientic Instruments.  79(4): 044302.  [PDF] [Abstract]

9. Yang, M.T., Sniadecki, N.J., Chen, C.S.  (2007)  Geometric Considerations of Micro- to Nanoscale Elastomeric Post Arrays to Study Cellular Traction Forces.  Advanced Materials.  19: 3119-3123.  [PDF]

8. Desai, R.A., Yang, M.T., Sniadecki, N.J., Legant, W.R., Chen, C.S.  (2007)  Microfabricated Post-Array-Detectors (mPADs): an approach to isolate mechanical force.  J Visualized Exp.  7.  [HTML]

7. Sniadecki, N.J., Anguelouch, A., Yang, M.T., Lamb, C.M., Liu, Z., Kirschner, S.B., Liu, Y, Reich, D.H., Chen, C.S.  (2007)  Magnetic microposts as an approach to apply forces to living cells.  Proc Nat Acad Sci.  104: 14553-14558.  [PDF]  [SUP MAT] 

6. Sniadecki, N.J., Chen, C.S.  (2007)  Microfabricated Silicone Elastomeric Post Arrays for Measuring Traction Forces of Adherent Cells  In Methods in Cell Biology - Cell Mechanics, Volume 83.  (ed. Y-L. Wang and D.E. Discher).  Elsevier: New York.  13:313-328.  [PDF] 

5. Sniadecki, N.J., Chen, C.S.  (2006)  Instrumentation for Cell Mechanics  In Medical Devices and Systems: The Biomedical Engineering Handbook, Third Edition.  (ed. J.D. Bronzino).  CRC Press: Boca Raton.  65:1-11.  [PDF] 

4. Sniadecki, N.J., Desai, R.A., Alom Ruiz, S., Chen, C.S.  (2006)  Nanotechnology for Cell-Substrate Interactions.  Annals of Biomed Eng.  34(1):431-441.  [PDF] 

3. Nelson, C.M., Jean, R.P., Tan, J.L., Liu, W.F., Sniadecki, N.J., Spector, A.A., Chen, C.S.  (2005)  Emergent patterns of growth controlled by multicellular form and mechanics.  Proc Nat Acad Sci.  102(33):11594-11599.  [PDF]  [SUP MAT] 

2. Lemmon, C.A., Sniadecki, N.J., Ruiz, S.A., Tan, J.T., Romer, L.H., Chen, C.S.  (2005)  Shear Force at the Cell-Matrix Interface: Enhanced Analysis For Microfabricated Post Array Detectors.  Mech Chem Biosys.  2(1):1-16.  [PDF] 

1. Sniadecki, N.J., Lee, C.S., Sivanesan, P., DeVoe, D.L.  (2004)  Induced Pressure Pumping in Polymer T-Channels via Field-Effect Flow Control.  Anal Chem.  76(7).  [PDF]