Publications:

  • Journal
  1. Mingyong Han, Xiaohu Gao, Jack Su, and Shuming Nie, “ Quantum-dot-tagged microbeads for multiplexed optical coding of biomolecules,” Nature Biotechnology 2001, 19, 631-635. (pdf reprint)
  2. Xiaohu Gao, Warren Chan, and Shuming Nie, “Quantum-dot nanocrystals for ultrasensitive biological labeling and multicolor optical encoding,” Journal of Biomedical Optics 2002, 7, 532–537. (pdf reprint)
  3. Warren Chan, Dustin Maxwell, Xiaohu Gao, Robert Bailey, Mingyong Han, and Shuming Nie, "Luminescent quantum dots for multiplexed biological detection and imaging," Current Opinion in Biotechnology 2002, 13, 40-46. (pdf reprint)
  4. Xiaohu Gao, and Shuming Nie, "Molecular profiling of single cells and tissue specimens with quantum dots," Trends in Biotechnology 2003, 21, 371-373. (pdf reprint)
  5. Xiaohu Gao, and Shuming Nie, “Doping mesoporous materials with multicolor quantum dots,” Journal of Physical Chemistry B 2003, 107, 11575-11578. (pdf reprint)
  6. Xiaohu Gao, and Shuming Nie, “QD-encoded mesoporous beads with high brightness and uniformity: rapid readout by flow cytometry,“ Analytical Chemistry 2004,76, 2406-2410. (pdf reprint)
  7. Xiaohu Gao, Yuanyuan Cui, Richard Levenson, Leland Chung, and Shuming Nie, “ In vivo cancer targeting and imaging with semiconductor quantum dots,” Nature Biotechnology 2004, 22, 969-976. (pdf reprint)
  8. Andrew Smith, Xiaohu Gao, and Shuming Nie, “ Quantum-dot nanocrystals for in-vivo molecular and cellular imaging,” Photochemistry and Photobiology 2004, 80, 377-385. (pdf reprint)
  9. Xiaohu Gao, Lily Yang, John A. Petros, Fray F. Marshall, Jonathan W. Simons, Leland Chung, and Shuming Nie, “In vivo molecular and cellular imaging with quantum dots,” Current Opinion in Biotechnology 2005, 16, 63-72. (pdf reprint)
  10. Andrew M Smith, Shivang Dave, Shuming Nie, Lawrence True and Xiaohu Gao, "Multicolor quantum dots for molecular diagnostics of cancer," Expert Review of Molecular Diagnostics 2006, 6, 231-244. (pdf reprint)
  11. Dardo E. Ferrara, Daiana Weiss, Peter H. Carnell, Ray P.Vito, David Vega, Xiaohu Gao, Shuming Nie and W. Robert Taylor, "Quantitative 3D fluorescence technique for the analysis of en face preparations of arterial walls using quantum dot nanocrystals and two-photon
    excitation laser scanning microscopy," American Journal of Physiology 2006, 290, R114-R123. (pdf reprint)
  12. Matthew N. Rhyner, Andrew M. Smith, Xiaohu Gao, Hui Mao, Lily Yang and Shuming Nie, "Quantum dots and multifunctional nanoparticles: new contrast agents for tumor Imaging," Nanomedicine 2006, 1, 209-217. (pdf reprint)
  13. Maksym V Yezhelyev, Xiaohu Gao, Yun Xing, Ahmad Al-Hajj, Shuming Nie and Ruth M O'Regan, "Emerging use of nanoparticles in diagnosis and treatment of breast cancer," The Lancet Oncology 2006, 7, 657-667. (pdf reprint)
  14. Lawrence D. True and Xiaohu Gao, "Quantum dots for molecular pathology-their time has arrived," Journal of Molecular Diagnostics 2007, 9, 7-11. (pdf reprint)
  15. Maksym V. Yezhelyev, Ahmad Al-Hajj, Caroline Morris, Adam I. Marcus, Tonqrui Liu, Melinda Lewis, Cynthia Cohen, Pasha Zrazhevskiy, JonathanW. Simons, Andre Rogatko, Shuming Nie, Xiaohu Gao and Ruth M. O’Regan, "In situ molecular profiling of breast cancer biomarkers with multicolor quantum dots," Advanced Materials, 2007, 19, 3146–3151. (pdf reprint)
  16. Jian Yang, Jonathan Gunn, Shivang R. Dave, Miqin Zhang, Y. Andrew Wang and Xiaohu Gao, "Ultrasensitive detection and molecular imaging with magnetic nanoparticles," Analyst 2008. (pdf reprint)
  17. Lifeng Qi, and Xiaohu Gao, Emerging application of quantum dots for drug delivery and therapy," Expert Opinion on Drug Delivery, 2008, 5,263-267. (pdf reprint)
  18. Jian Yang, Shivang R. Dave, and Xiaohu Gao, "Quantum dot nanobarcodes: epitaxial assembly of nanoparticle-polymer complexes in homogeneous solution," Journal of the American Chemical Society, 2008, 130, 5286-5292. (pdf reprint)
  19. Lifeng Qi, and Xiaohu Gao, "Quantum DotAmphipol Nanocomplex for Intracellular Delivery and Real-Time Imaging of siRNA," ACS Nano, 2008. (pdf reprint)
  20. Maksym Yezhelyev, Lifeng Qi, Ruth M. O’Regan, Shuming Nie, and Xiaohu Gao, "Proton-sponge coated quantum dots for siRNA delivery and intracellular imaging," Journal of the American Chemical Society, 2008. (pdf reprint)
  • Conference Proceedings
  1. Xiaohu Gao, Mingyong Han, and Shuming Nie, "Optically encoded microspheres for high-throughput analysis of genes and proteins," Proc. SPIE 2001, 4626, 210-217.
  2. Xiaohu Gao, and Shuming Nie, "Semiconductor quantum dots for multicolor fluorescence imaging and spectroscopy of single cancer cells," MRS Proceedings, 2003, 773, N 1.5.
  3. Amit Agrawal, Xiaohu Gao, Nitin Nitin, Gang Bao, and Shuming Nie, "Quantum dots and fret-nanobeads for probing genes, proteins, and drug targets in single cells," Proceedings of IMECE, 2003, IMECE2003-43598.
  4. Xiaohu Gao and Shuming Nie, "Long-circulating QD probes for in vivo tumor imaging," Proc. SPIE 2004, 5593, 292-299.
  5. Aileen Wu and Xiaohu Gao, " Multiplexed and quantitative study of biomarker expression in tumor specimens using quantum dots," SPIE 2006, 6096: 257-265.
  • Invited Book Chapters
  1. Xiaohu Gao, and Shuming Nie, “Quantum-dot-encoded beads” in Bionanotechnology Protocols, Humana Press Inc. 2003.
  2. Xiaohu Gao, and Shuming Nie, “Semiconductor quantum dots and optically encoded microbeads for gene expression analysis” in Perspectives in Gene Expression, Eaton Publishing 2003.
  3. Xiaohu Gao, and Shuming Nie, "Luminescent quantum dots for biological labeling," in NanoBiotechnology, Wiley-VCH Publishers, 2004.
  4. Warren Chan, Xiaohu Gao, and Shuming Nie, “Quantum dots as fluorescent labels for molecular biotechnology and bioengineering,” in Colloids and Colloid Assemblies: Synthesis, Modification, Organization, and Application, Wiley-VCH Publishers, 2004.
  5. Xiaohu Gao, Leland WK Chung and Shuming Nie, "Quantum Dots for In-vivo Molecular and Cellular Imaging," in Methods in Molecular Biology, Humana Press Inc. 2005.
  6. Xiaohu Gao, Max Yezhleyev, Yun Xing and Shuming Nie, “Bioconjugated Quantum Dots for Sensitive and Multiplexed Immunoassays,” in A Reference Book for Immunoassay and Other Bioanalytical Methods, Marcel Dekker Inc. 2005.
  7. Xiaohu Gao and Shuming Nie, "Nanotechnolog in chemistry, biology and medicine," in Microsystems and Nanotechnology, Chapter written in Chinese, Science Press, China, 2005.
  8. Xiaohu Gao, Yun Xing, Leland CW Chung and Shuming Nie, “Quantum Dot Nanotechnology for Prostate Cancer” in Prostate Cancer: Novel Biology, Genetics and Therapy 2005.
  9. Amit Agrawal, Yun Xing, Xiaohu Gao, and Shuming Nie, “Quantum dots,” in Nanotechnology in Biology and Medicine, CRC press. 2006.
  10. Gang Ruan, Amit Agrawal, Andrew M. Smith, Xiaohu Gao, and Shuming Nie, "Quantum dots as fluorescent labels for molecular and cellular imaging," in Reviews in Fluorescence , Annual volumes 2006. 2006.
  11. Xiaohu Gao and Shivang Dave, "Quantum dots for cancer molecular imaging," in Biological and Biomedical Applications of Engineered Nanostructures, Landes Bioscience/Eurekah, 2006.
  12. Pavel Zrazhevskiy and Xiaohu Gao, "Molecular profiling of cancer cells and tissues using multicolor quantum dots," in Nanomaterials: Inorganic and Bioinorganic Perspectives, John Wiley & Sons, Ltd. 2007.
  • Patents
  1. Xiaohu Gao, and Shuming Nie, “Porous materials embedded with nanospecies, methods of fabrication thereof, and methods of use thereof,”United States Patent number 7,037,729.
  2. Mingyong Han, Xiaohu Gao, and Shuming Nie, “Methods of preparing multicolor quantum dot tagged beads and conjugates thereof,“ Filed in 2001, US and International Patents Pending.
  3. Xiaohu Gao, and Shuming Nie, “Bioconjugated nanostructures, methods of fabrication thereof, and methods of use thereof,” Filed in 2003, US and International Patents Pending.
  4. Xiaohu Gao, and Shuming Nie, “Multimodality nanostructures, methods of fabrication thereof, and methods of use thereof,” Filed in 2004, US and International Patents Pending.

 

Invited Talks:

  1. “Highly luminescent quantum dot nanocrystals and bio-analytical applications,” Pittsburgh Conference, New Orleans, LA, 2001.
  2. “Luminescent quantum dots for optical encoding and molecular imaging,” Department of Chemistry and Department of Radiology, University of Pennsylvania, 2003.
  3. “Luminescent quantum dots for optical encoding and cancer profiling,” American Chemical Society's 225th National Meeting, Industry Pavilion, New Orleans, LA, 2003.
  4. “Optical-encoded microbeads for multiplexed analysis of genes, proteins, and cells,” Materials Research Society Meeting, San Francisco, CA, 2003.
  5. “ Optical-encoded microbeads for multiplexed analysis of genes, proteins, and cells,” SmallTalks2003, San Jose, CA, 2003.
  6. “Luminescent quantum dots for multicolor and ultrasensitive cellular imaging,” ASME International Mechanical Engineering Congress and R and D Expo, Washington , D.C. , 2003.
  7. “Fluorescent quantum dots for molecular imaging and multiplexed gene screening,” NIEHS-CMGCC / NCI-MMHCC Mouse Phenotyping Forum, Austin, TX, 2004.
  8. “Quantum Dot-Encoded Beads as Invisible Taggants,” DARPA workshop Nanoparticle Taggants for Military Applications, San Francisco, CA, 2004.
  9. “Probing single molecules and single cells with quantum dots,” 228th ACS National Meeting, Philadelphia, PA, 2004.
  10. “Luminescent quantum dots and optically encoded beads for multiplexed biological detection and imaging,” International Symposium on Optics East, Philadelphia, PA, 2004 (Keynote lecture).
  11. “Luminescent quantum dots for molecular imaging and optical encoding,” Department of Biomedical engineering, University of California, Davis, CA, 2004.
  12. “Biomedical applications of nanomaterials,” USAMRMC TATRC Nanomedicine Integrated Research Team Meeting, Frederick, MD, 2005.
  13. “Bioconjugated quantum dots and nanoparticle probes for molecular and cellular imaging,” 229th American Chemical Society National Meeting, Novel Directions in Photonics: Nanophotonics and Biophotonics, San Diego, CA, 2005.
  14. “Luminescent quantum dots for molecular imaging and optical encoding,” Department of Biomedical engineering, University of Florida, Gainesville, FL, 2005.
  15. “Multicolor quantum dots for optical barcoding and molecular analysis,” 229th American Chemical Society National Meeting, ACS Nobel Laureate Signature Award Symposium: Spectroscopy at the Nanoscale, San Diego, CA, 2005.
  16. “Luminescent quantum dots for molecular imaging and optical encoding,” Department of Biomedical engineering, University of Wisconsin, Madison, WI, 2005.
  17. “Luminescent quantum dots for molecular imaging and optical encoding,” Department of Bioengineering, Stanford University, Palo Alto, CA, 2005.
  18. “Luminescent quantum dots for molecular imaging and drug delivery,” Cancer Center, University of Colorado at Denver, 2005.
  19. “Multifunctional nanoparticles for imaging and therapeutics,” Fred Hutchinson Cancer Research Center, Seattle, WA, 2005.
  20. “Luminescent quantum dots for cellular and molecular imaging,” Photonics West, San Jose, CA 2006.
  21. “Molecular imaging and drug delivery using multifunctional nanoparticles,” Department of Chemistry, Arizona State University, Tempe, AZ, 2006.
  22. “Probing single molecules and single cells with quantum dots”, International Workshop on Single Molecule Analysis, Okinawa, Japan, 2006.
  23. “Luminescent quantum dots for cellular and molecular imaging,” Focus on Microscopy, Perth, Australia 2006 (plenary session) 2006.
  24. “Cancer nanotechnology,” Department of Chemistry, Nankai Univeristy, Tianjin, China, 2006.
  25. “Quantum dot nanoparticles for molecular imaging,” Particles2006, Orlando, FL, 2006.
  26. “Multifunctional nanoparticles for molecular imaging and bioengineering,” Department of Chemistry, Western Washington University, WA, 2007.
  27. “Functional nanostructures and their biomedical applications,” Workshop on Safety, Health, & Environmental Aspects of Engineered Nanomaterials. Singapore, 2007.
  28. "Luminescent Quantum Dots for Cancer Research” Department of Chemical and Biomolecular Engineering, National University of Singapore, Singapore, 2007.
  29. “Luminescent quantum dots for molecular imaging and ultrasensitive detection,” Institute of Bioengineering and Nanotechnology, Singapore, 2007.
  30. "Nanoparticle probes for molecular imaging and therapy," the Pacific Northwest Association of Toxicologists 2007 Annual Meeting, Seattle, WA 2007.
  31. "Nanoparticle probes for molecular imaging and therapy," Biomedical Engineering Society Annual Meeting, Los Angeles, CA 2007 .
  32. "Luminescent quantum dots for molecular imaging and cellular imaging," American Vacuum Society 54th International Symposium and Exhibition, Seattle, WA 2007.
  33. “Scrutinizing cancer with quantum dot technology,” The 12th Shizuoka Forum on Health and Longevity, Hamamatsu, Japan (plenary session) 2007.
  34. “Multifunctional QDs for molecular imaging and siRNA delivery,” Biomedical Optics Topical Meeting (BIOMED), St. Petersburg, Fl, (plenary session) 2008.
  35. “Quantum dot nanobarcodes” 2008 Emory-GT Frontiers of Cancer Nanotechnology Symposium, Atlanta, GA 2008.
  36. "Simultaneous imaging and delivery of siRNA with quantum dots," Particles 2008, Orlando, Fl, 2008.