Posted December 1, 2019
This position will work in a research group focused on genomics and physiology in shellfish. One primary project seeks to develop a novel means to produce reproductively sterile shellfish, which are both a market driven need for increased growth and palatability, and an ecologically sustainable approach to mitigate concerns associated with genetic perturbation of wild populations of conspecifics. This collaborative project between researchers at the University of Washington and NOAA Northwest Fisheries Science Center will develop tools and protocols to induce sterility by inactivation of genes essential for primordial germ cell (i.e. future gamete) formation. The postdoc will be responsible for addressing two critical phases in the development of this approach: 1) Identification and characterization of genes involved in germ cell development in bivalve embryos using single-cell RNA sequencing (scRNA-Seq), and 2) Development and optimization of protocols to temporarily silence gene expression (e.g. morpholino or CRISPR-Cas9 delivery) in bivalve embryos.
As the recruited person will be highly involved in both the scRNA-Seq analyses and the gene silencing protocol development, we are seeking a prospective candidate with demonstrated experience analyzing functional genomic datasets and/or delivering gene-silencing (knockdown or knockout) molecules to early stage embryos. Prior experience working with shellfish or other invertebrates would also be a plus.
PhD or equivalent in developmental biology, genomics, bioinformatics, or a related field
Highly motivated and independent scientist that works well with a research team
Desired (non-essential) background:
Previous experience with functional genomics datasets (e.g. RNA-Seq)
Previous experience in gene knock-down/knock-out technology
Familiarity with bivalve embryonic development and larval rearing practices
For consideration please send a CV and names of three references to Steven Roberts (email@example.com).
The position will remain open until it is filled.