Effect of 2D Velocity Profiles on Optical Measurements

 

 

Nicholas Tapias

 

 

University of Washington

Department of Chemical Engineering

June 1, 2006

 

 

 

Microfluidic devices involve fluid flow through channels at flow rates that are not easily measured using conventional techniques. Typically the only way to access the dimensions of the channel is using optics. The ultimate goal is to develop generalized charts that can be used to characterize fluid flow through rectangular microchannels of various aspect ratios and boundary conditions using the Poisson equation. The Poisson equation relates the velocity distribution in a space where the pressure drop, viscosity and path length are known.

For the purposes of these calculations, the quantity  was assigned as unity. The physical dimensions of the microchannels investigated in this research are listed below.

 

Closed Channel

 

Open Channel

Aspect Ratio

Width (µm)

Height (µm)

 

Aspect Ratio

Width (µm)

Height (µm)

1:1

1

1

 

1:1

1

1

1:2

2

1

 

1:2

2

1

1:3

3

1

 

1:3

3

1

1:4

4

1

 

1:4

4

1

1:5

5

1

 

1:5

5

1

1:6

6

1

 

1:6

6

1

 

The depth of each channel was defined as 1μm and the width was varied dependent upon the aspect ratio investigated. An important part of this experiment was to compare the flow through closed and open channel conditions. Figure 1 illustrates the boundary conditions used for each closed and open channel arrangement. No-slip boundary conditions were imposed upon the entire exterior boundary of the closed channel arrangements. Open channel arrangements were modified with a slip or symmetry boundary at the top of the channel, allowing for the fluid to flow freely at this boundary. As indicated in the figure symmetry was used to simplify the calculation and increase the accuracy of the calculation using the finite element software. Another consequence of this symmetry is the repetition of measurements. One such repetition is that of an open channel 1:2 being also representative of a closed channel 1:1. The slip boundary at the top in such an open channel is equivalent to a symmetric line that divides such a 1:1 channel, but for the purposes of this research it is important to consider each case separately, as the fraction of the total flow for each subdomain is different as the boundary condition is altered. A slip or symmetry boundary was placed at the midpoint across the channel since we know that the flow characteristics of the right side will be a reflection of the left side.

 

 

To solve this problem within the FEMLAB software, the geometry of the channel was specified and the aforementioned boundary conditions were designated. As mentioned above the solutions were calculated for half of the total width of the channel because of the symmetrical nature of the channel. This allowed for higher accuracy near the boundary and higher resolution for the characteristic flow curve. Table 2 shows the properties of the solutions calculated from FEMLAB. The flow through each subdomain of the channel was evaluated using subdomain integration in FEMLAB. The equation below shows the relation between velocity and flow rate.

 

 

The size of each subdomain varied across the whole domain. The width of the subdomains near the edge was approximately 4 nm wide. The largest subdomain examined was 0.3 μm. The lines visible in Figure 2 show the relative size of each examined subdomains for the 1:6 configuration channel. Additional variability in the dimensions of the larger elements of the domain was included to ensure that measurements were representative of the actual flow profile through the channel. This can be seen in the figure as well, as each subdomain on the right side of the figure is not identical to the previous one. Having this variability also ensures that the placement of elements within the domain are equally distributed and that accuracy of the measurement is not restricted only to the very small subdomains.

 

 

 

 

 

Some important flow characteristics can be seen in these two generalized charts. The linear behavior of the flow accumulation after approximately 1/3 of the channel width is realized. This can be interpreted to represent that the vertical velocity profile after this point is constant. Also important to note from these generalized correlations is the variation near the no-slip boundary. The fraction of flow near the edge is significantly different for the different aspect ratios investigated.

 

Also shown on the plots are the conditions where the side walls of the channel were not designated as no-slip boundaries. This result would be representative of the flow for a channel with infinite width. The charts indicate that the fraction of flow to a specific width in the channel. The tables below show the third-order correlations of the fractional flow and the fractional width. Also shown are the R2 values that were calculated. Each of these correlations were restricted to have zero flow at the left boundary (u(x=0) = 0).

 

Closed Channel

 

 

Open Channel

 

Aspect Ratio

 

R2

 

Aspect Ratio

 

R2

1:1

y = -0.5634x3 + 1.5283x2 + 0.0344x

1

 

1:1

y = -0.5224x3 + 1.5104x2 + 0.0118x

1

1:2

y = -0.6889x3 + 1.598x2 + 0.0901x

0.9999

 

1:2

y = -0.5729x3 + 1.5437x2 + 0.0289x

1

1:3

y = -0.7337x3 + 1.5484x2 + 0.1806x

0.9998

 

1:3

y = -0.6189x3 + 1.5534x2 + 0.0635x

1

1:4

y = -0.707x3 + 1.426x2 + 0.2742x

0.9997

 

1:4

y = -0.6497x3 + 1.5388x2 + 0.1075x

0.9999

1:5

y = -0.6977x3 + 1.3427x2 + 0.3468x

0.9996

 

1:5

y = -0.6916x3 + 1.5375x2 + 0.149x

0.9999

1:6

y = -0.6633x3 + 1.2346x2 + 0.4182x

0.9995

 

1:6

y = -0.7132x3 + 1.5083x2 + 0.1973x

0.9998

 

 

Using these correlations it is possible to calculate the fractional flow that is contained within a specific portion of the channel of interest. An important result of this as well is that channels with aspect ratios less than 1:4 have a rapidly changing velocity profile near the fixed edges, whereas those with larger aspect ratios exhibit constant velocity profiles after the 1:4 aspect ratio has been realized. Figure 6 below further illustrates this case in 1:12 aspect ratio channels.

 

These linear profiles allows for easier determination of the flow rate through the channels. Because the flow is then simply a function of the width of interest, the cumulative flow rate will be a linear profile. The width necessary for each aspect ratio to recover this linear velocity profile was determined analytically by satisfying the condition in the equation below.

This condition states that at the point where the velocity profile stops changing in the x-direction along the channel, the flow rate as well should not be changing. This condition was then applied to the correlations obtained for fractional flow through the microchannels. The figure below illustrates how the fractional width along the channel for each aspect ratio to recover this linear velocity profile.

 

These results can then be applied to determine the physical scale of these fractional widths. Table 5 below shows that as the aspect ratio increases, the linear velocity profile is recovered further in the x-direction than for smaller channels. An important result of this is that for different aspect ratios, the fraction to recover the linear velocity profile is different. As the channel widens a larger portion of the total flow is considered in the region of constant x-velocity.

 

Closed Channel

 

Open Channel

Aspect Ratio

Width (µm)

 

Aspect Ratio

Width (µm)

1:1

0.452

 

1:1

0.482

1:2

0.773

 

1:2

0.898

1:3

1.055

 

1:3

1.255

1:4

1.345

 

1:4

1.579

1:5

1.604

 

1:5

1.853

1:6

1.861

 

1:6

2.115

 

Also worth noting is that it requires more length along the x-direction to establish the linear x-velocity profile for the open channel than for the closed channel for all scenarios investigated. These results could be used to find the proper site to find the mean flow rate along the length of the channel.

 

Paper.

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