Neurotoxins

Name		    Source		Neuronal Action
----------	    ------		---------------
agotoxin	    Funnel Web Spider   Blocks calcium channels
alpha-bungarotoxin  Krait		Blocks acetylcholine receptor
Anatoxin	    Algae		Acetylcholine receptor agonist
Apamin		    Honey bee   	Blocks potassium channels
Batrachotoxin       Poison Arrow Frog   Prevents sodium channel closure
Botulinum toxin	    Bacteria    	Blocks acetylcholine release
Brevetoxin	    Red Tide Dinofl.    Activates sodium channels
Capsaicin	    Cayenne Pepper	Excites peripheral nerve endings
Charybdotoxin	    Scorpion    	Blocks potassium channels
Chlorotoxin	    Scorpion	 	Blocks chloride channels
Conotoxin	    Cone Snail		Blocks calcium channels
Crotoxin	    Rattlesnake	        Reduces acetylcholine release
Dendrotoxin	    Green Mamba	        Blocks voltage-gated potassium ch.
Domoic acid	    Blue mussel	  	Glutamate/kainate receptor agonist
Gonyautoxin	    Dinoflagellate	Block sodium channels
Iberiotoxin	    Scorpion		Blocks potassium channels
Joro spider toxin   Joro spider		Blocks glutamate receptors
Kaliotoxin	    Scorpion		Blocks potassium channels
Latrotoxin	    Black widow Spider  Enhances neurotransmitter release
Mandarntoxin	    Wasp		Blocks sodium action potentials
Notexin		    Tiger snake		Reduces ACh release
Noxiustoxin	    Scorpion	   	Blocks sodium channels
Palytoxin           Soft coral		Activates sodium channels
Paradaxin	    Pacific sole	Increases neurotransmitter release
Saxitoxin           Dinoflagellate	Blocks sodium channels
Tetrodotoxin (TTX)  Pufferfish 		Blocks sodium conductance
A good reference for NEUROTOXINS is: Trends in Neuroscience, June, 1996 (supplement).

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