PUBLICATIONS

Akiyoshi B, Sarangapani KK, Powers AF, Nelson CR, Reichow SL, Arellano-Santoyo H, Gonen T, Ranish JA, Asbury CL, Biggins S, "Tension directly stabilizes reconstituted kinetochore-microtubule attachments" (2010) Nature, 468(7323):576-9. (pdf)
Discussed in: Shimamoto Y, "Cellular seat belts" (2010) Nature, 468(7323):518-9. (pdf)

Asbury CL, Tien JF, Davis TN, "Kinetochores' gripping feat: biased diffusion or conformational wave?" (2011) Trends in Cell Biology., 21(1):38-46. (pdf)

Tien JF, Umbreit NT, Gestaut DR, Franck AD, Cooper J, Wordeman L, Gonen T, Asbury CL, Davis TN, "Cooperation of the Dam1 and Ndc80 kinetochore complexes enhances microtubule coupling and is regulated by aurora B" (2010) Journal of Cell Biology, 189(4):713-23. (pdf)
Discussed in: Short B, "Kinetochores hang on for the ride" (2010) Journal of Cell Biology, 189(4):615. (pdf)

Wargacki MM, Tay JC, Muller EG, Asbury CL, Davis TN, "Kip3, the yeast kinesin-8, is required for clustering of kinetochores at metaphase" (2010) Cell Cycle, 9(13):2581-8. (pdf)
Discussed in: Rizk R, Gupta ML, "Kip3 clusters kinetochores" (2010) Cell Cycle, 9(13):2496. (pdf)
Discussed in: Ohi R, "Kip3-ing kinetochores clustered" (2010) Cell Cycle, 9(13):2497. (pdf)

Gestaut DR, Cooper J, Asbury CL, Davis TN, Wordeman L, "Reconstitution and functional analysis of kinetochore subcomplexes" (2010) Methods in Cell Biology, 95:641-56. (pdf)

Franck AD, Powers AF, Gestaut DR, Davis TN, Asbury CL, “Direct physical study of kinetochore-microtubule interactions by reconstitution and interrogation with an optical force clamp” (2010) Methods, 51(2):242-50. (pdf)

Powers AF, Franck AD, Gestaut DR, Cooper J, Gracyzk B, Wei RR, Wordeman L, Davis TN, Asbury CL, “The Ndc80 kinetochore complex forms load-bearing attachments to dynamic microtubules via biased diffusion” (2009) Cell, 136:865-875. (pdf)
Discussed in: Joglekar AP and DeLuca JG, "Chromosome segregation: Ndc80 can carry the load" (2009) Current Biology, R404-R407. (pdf)
Discussed in: Gray L, "Single molecule tracking helps reveal mechanism of chromosome separation in dividing cells" (2009) UW news and information. (link)
Online interview with Chip: posted at Cell PaperClips (podcast)

Cooper JR, Wagenbach M, Asbury CL, Wordeman L, "Catalysis of the microtubule on-rate is the major parameter regulating the depolymerase activity of MCAK" (2009) Nature Structural & Molecular Biology, 17(1):77-82. (pdf)

Fehr A, Gutiérrez-Medina B, Asbury CL, Block SM, “On the origin of kinesin limping” (2009) Biophysical Journal, 97(6):1663-1670. (pdf)

Asbury CL and Davis TN, “Insights into the kinetochore” (2008) Structure, 16:834-836. (pdf)

Asbury CL, “XMAP215: a tip tracker that really moves” (2008) Cell, 132:19-20. (pdf)

Gestaut DR, Graczyk B, Cooper J, Widlund PO, Zelter A, Wordeman L, Asbury CL, and Davis TN, “Phosphoregulation and depolymerization-driven movement of the Dam1 complex do not require ring formation” (2008) Nature Cell Biology, 10(4):407-414. (pdf)
Discussed in: Gardner MK and Odde DJ, "Dam1 complexes go it alone on disassembling microtubules" (2008) Nature Cell Biology 10(4):379-381. (pdf)

Fehr A, Asbury CL, Block SM, “Kinesin steps do not alternate in size” (2008) Biophysical Journal, 94(3):L20-22. (pdf)

Stumpff J, Von Dassow G, Wagenbach M, Asbury CL, Wordeman L, “The Kinesin-8 motor Kif18A suppresses kinetochore movements to control mitotic chromosome alignment” (2008) Developmental Cell, 14:252-262. (pdf)
Discussed in: Gardner MK, Odde DJ, and Bloom K, "Kinesin-8 molecular motors: putting the brakes on chromosome oscillations" (2008) Trends in Cell Biology 18(7):307-310. (pdf)

Stumpff J, Asbury CL, “Chromosome bi-orientation: euclidian euploidy” (2007) Current Biology, 18(2):R81-83. (pdf)

Franck AD, Powers AF, Gestaut DR, Gonen T, Davis TN, and Asbury CL, “Tension applied through the Dam1 complex promotes microtubule elongation providing a direct mechanism for length control in mitosis” (2007) Nature Cell Biology, 9:832-837. (pdf)
Discussed in: Gardner MK, Hunt AJ, Goodson HV, and Odde DJ, "Microtubule assembly dynamics: new insights at the nanoscale" (2008) Current Opinion in Cell Biology, 20:64-70. (pdf)

Asbury CL, Gestaut DR, Powers AF, Franck AD, and Davis TN, “The Dam1 kinetochore complex harnesses microtubule dynamics to produce force and movement” (2006) Proc. Natl. Acad. Sci. USA, 103(26):9873-9878. (pdf)

Asbury CL “Kinesin: World’s Tiniest Biped” (2005) Current Opinion in Cell Biology, 17:89-97. (pdf)

Asbury CL, and Block SM, “Motor proteins” (2005) in Encyclopedia of Molecular Cell Biology and Molecular Medicine, RA Meyers, Ed., Wiley-VCH, Weinheim, Germany, pgs. 575-600. (pdf)

Asbury CL, Fehr AN, and Block SM, “Kinesin Moves by an Asymmetric Hand-over-hand Mechanism” (2003) Science, 302:2130-2134. (pdf)
Discussed in: Perkel JM "Investigating molecular motors step by step" (2004) The Scientist, 18:19-23. (pdf)
Discussed in: "Breakthrough of the year: the runners-up" (2003) Science, 302:2039-2045. (pdf)

Block SM, Asbury CL, Shaevitz JW, and Lang MJ, “Probing the Kinesin Reaction Cycle with a Two-Dimensional Optical Force Clamp” (2003) Proc. Natl. Acad. Sci. USA, 100(5):2351-2356. (pdf)

Lang MJ, Asbury CL, Shaevitz JW, and Block SM, “An Automated Two-Dimensional Optical Force Clamp for Single Molecule Studies” (2002) Biophysical Journal, 83:491-501. (pdf)

Uy JL, Asbury CL, Petersen TW, and van den Engh G, “The polarization of fluorescence of DNA stains depends on the incorporation density of the dye molecules” (2004) Cytometry, 61:18-25. (pdf)

Asbury CL, Diercks AH, and van den Engh G, “Trapping of DNA by Dielectrophoresis” (2002) Electrophoresis, 23:2658-2666. (pdf)

Asbury CL, Uy JL, and van den Engh G, “Polarization of Scatter and Fluorescence Signals in Flow Cytometry” (2000) Cytometry, 40:88-101. (pdf)
Discussed in: Shapiro HM, "Everything you never wanted to know about polarization -- but were afraid you might find out" (2000) Cytometry 40:87. (pdf)

Asbury CL, and van den Engh G, “Trapping of DNA in Nonuniform Oscillating Electric Fields” (1998) Biophysical Journal, 74:1024-1030. (pdf)

Asbury CL, Esposito R, Farmer C, and van den Engh G, “Fluorescence Spectra of DNA Dyes Measured in a Flow Cytometer” (1996) Cytometry, 24:234-242.

Peattie RA, Asbury CL, Bluth EI, and Ruberti JW, “Steady Flow in Models of Abdominal Aortic Aneurysms. Part I: Investigation of the Velocity Patterns” (1996) Journal of Ultrasound in Medicine, 15:679-688.

Peattie RA, Asbury CL, Bluth EI, and Ruberti JW, “Steady Flow in Models of Abdominal Aortic Aneurysms. Part II: Wall Stresses and their Implication for In Vivo Thrombosis and Rupture” (1996) Journal of Ultrasound in Medicine, 15:689-696

Asbury CL, Ruberti JW, Bluth EI, and Peattie RA, “Experimental Investigation of Steady Flow in Rigid Models of Abdominal Aortic Aneurysms” (1995) Annals of Biomedical Engineering 23:29-39.