Program: | beagle 5.4 (version: 06Aug24.a91) |
Author: | Brian Browning |
Email: | browning@uw.edu |
Beagle is a software package for phasing genotypes and imputing ungenotyped markers. Beagle version 5.4 has improved memory and computational efficiency when analyzing large sequence data sets.
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If you use Beagle in a published analysis, please report the program version and cite the appropriate article.
The Beagle 5.4 genotype phasing method is described in:
B L Browning, X Tian, Y Zhou, and S R Browning (2021) Fast two-stage phasing of large-scale sequence data. Am J Hum Genet 108(10):1880-1890. doi:10.1016/j.ajhg.2021.08.005
The Beagle 5.4 genotype imputation method is described in:
B L Browning, Y Zhou, and S R Browning (2018). A one-penny imputed genome from next generation reference panels. Am J Hum Genet 103(3):338-348. doi:10.1016/j.ajhg.2018.07.015
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Beagle is free software: you can redistribute it and/or modify it under the terms of the GNU General Public License as published by the Free Software Foundation, either version 3 of the License, or (at your option) any later version.git
Beagle is distributed in the hope that it will be useful, but WITHOUT ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU General Public License for more details.
You can download a copy of the the GNU General Public License from https://www.gnu.org/licenses/.
Source files in the net/sf/samtools/ directory are from the Broad Institute and are used to perform BGZIP compression and decompression. Source files from the Broad Institute are licensed under the MIT license.
beagle.06Aug24.a91.jar | Beagle 5.4 program file (requires Java version 8) |
beagle_5.4_18Mar22.pdf | Beagle 5.4 documentation |
run.beagle.06Aug24.a91.example | a unix script which runs a short Beagle 5.4 analysis |
beagle5_release_notes | description of post-release changes in Beagle version 5 |
gpl_license | GNU General Public License |
The following resources are also available:
human genetic maps | HapMap GrCh36, GrCh37, and GrCh38 genetic maps with cM units in PLINK format |
human reference panel | 1000 Genomes Project phase 3 reference panel |
bref3.06Aug24.a91.jar | Converts from VCF format to bref3 format. Enter "java ‑jar bref3.06Aug24.a91.jar help" for usage instructions |
unbref3.06Aug24.a91.jar | Converts from bref3 format to VCF format. Enter "java ‑jar unbref3.06Aug24.a91.jar help" for usage instructions |
Variant Call Format | An introduction to Variant Call Format (VCF) |
conform-gt | a program for making alleles in a VCF file consistent with a reference VCF file |
Beagle Utilities | a suite of utility programs |
Beagle 5.3 | the Beagle 5.3 web page |
Beagle 5.2 | the Beagle 5.2 web page |
Beagle 5.1 | the Beagle 5.1 web page |
Beagle 4.1 | the Beagle 4.1 web page |
bref3.24May18.pdf | The bref3 file format specification |
beagle.240806.zip | source code for Beagle 5.4 (06Aug24.a91) |
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Copyright: 2013-2024 Brian L. Browning
Last updated: August 6, 2024