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ChemE436/Bioeng436.
Biochemical Engineering
Reading and Supplementary Materials
Jumpstation
Microbial diversity and basic cell biology
Animated structures of eukaryotic and bacterial cells at Cells Alive
Bacterial cell structures at Wikipedia
Major groups of prokaryotes at the Textbook of Bacteriology
A guided tour through Yellowstone in search of Life at High Temperatures
A classified photo gallery of pathogenic bacteria by Neil Chamberlain
A searchable image gallery of various microbial and animal species by Dennis Kunkel
A discussion of bacterial motility with videos at Microbiologybytes
A definition of taxonomy and a tutorial on how to read and construct evolutionary trees
Growth media and laboratory techniques to cultivate bacteria
Carbohydrates and lipids
An introduction to carbohydrates (PDF)
Carbohydrate chapter at the Natural Products Virtual Textbook
Carbohydrates at Wikipedia
An introduction to lipids (PDF)
Lipid chapter at the Natural Products Virtual Textbook
Lipids at Wikipedia
Additional information on macromolecules and membranes at NetBiochem
Proteins
Physico-chemical properties and images of amino acids at Berlin Institute of Chemistry
Pictures and movies of amino acids from Song Tan's laboratory
An introduction to proteins (PDF)
A simplified introduction to Protein Folding at Edinburgh University
Proteins, peptides and amino acids chapter of the Natural Products Virtual Textbook
Pictures and movies of secondary structure elements from Song Tan's laboratory
Principles of Protein Structure and Modeling at Expasy
Pictures and movies of selected proteins from Song Tan's laboratory
Movies of proteins in motion, unfolding and aggregating from Valerie Daggett's laboratory
Types and mechanisms of post-translational modifications
Additional information on enzyme kinetics at Wikipedia
A series of animations showing how to experimentally determine enzyme kinetics
Excellent (but slow) enzyme kinetics animations by Peter Birch
Nucleic acids
Nucleic acids chapter of the Natural Products Virtual Textbook
An interactive animated tutorial on DNA structure by Eric Martz
Replication, transcription and translation
The genetic code at Ultranet
A discussion of the validity of the central dogma of molecular biology
An introduction to transcription at Wikipedia
An introduction to transcription at Ultranet
An animation of eukaryotic transcription on YouTube
Information on bacterial RNA polymerase and alternative sigma factors at Memorial University
An introduction to translation at Ultranet
The ribosome at Wikipedia
An animation of eukaryotic translation on YouTube
Regulation of gene expression
Classes of DNA binding proteins including interactive links to the protein data bank
An example of a DNA binding protein-DNA complex: CRP (use Images and Visualization window)
A video of the lac operon on YouTube
Decription of the tryptophan (trp) and arabinose (ara) operons by Martin Mulligan
A course on control of gene expression in prokaryotes and eukaryotes at Indiana State
Mutations and mutagenesis
A discussion of mutations, mutagenesis and site-directed mutagenesis at Memorial University
Recombinant DNA technology and beyond
A course on plasmids and plasmid replication at Memorial University
All information that you may wish for on restriction enzymes at REBASE
An overview of restriction endonucleases at New England Biolabs
Examples of restriction endonucleases at New England Biolabs
Introduction to recombinant DNA technology at Ultranet
Description of the polymerase chain reaction at Wikipedia and a PCR tutorial
Animations of PCR from the Dolan DNA Learning Center at and McGraw Hill
A link repository for molecular biology and other protocols
Human genes, maps, proteins and diseases on GeneCards
Cell growth
Nutrition and growth of bacteria at the Textbbook of bacteriology
Experimental determination of bacterial growth curves and growth rates
The Monod equation and a java applet allowing you to manipulate the coefficients
Other models for cell growth including double substrate limitation and inhibited kinetics
A java applet illustrating diauxic growth
Sterilization
An description of sterilization techniques at Wikipedia
A discussion of continuous sterilization at RPI
A discussion of air sterilization at RPI
Fermentation
Extensive information on continuous cultivation of microorganisms at RPI
Fermentation equipment from New Brunswick Scientific
Fed-batch systems at RPI
Semi-continuous cultures at RPI
Determination of oxygen transfer rates at RPI
Dimensionless numbers and scale-up at RPI
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Contact: François Baneyx, University of Washington, Department of Chemical Engineering, Box 351750, Seattle, WA Tel: 206-685-7659 Fax: 206-685-3451 E-mail: baneyx@u.washington.edu