Immune and Inflammatory Cell Signatures
in Disease Progression


PUBLICATIONS

  • Machine learning integration of scleroderma histology and gene expression identifies fibroblast polarization as a hallmark of clinical severity and improvement
  • Global skin gene expression profile of early diffuse cutaneous systemic sclerosis shows a prominent innate and adaptive inflammatory profile
  • Mycophenolate Mofetil Treatment of Systemic Sclerosis Reduces Myeloid Cell Numbers and Attenuates the Inflammatory Gene Signature in Skin
  • Microbiome dysbiosis is associated with disease duration and increased inflammatory gene expression in systemic sclerosis skin