Description of file carot-longitudinal.dat: ptid = patient id number month = approximate study month datey = year of sample datem = month of sample dated = day of sample tm = time of sample ndays = days since last measurement bcarot = plasma beta carotene ret = plasma retinol retpalm = plasma retinol palmitate vite = plasma vitamin E dose = dose group patient randomized into lasty = year of last dosage administered lastm = month of last dosage administered lastd = day of last dosage administered lasttm = time of last dosage administered NOTE: (0) The values -9, -99 etc. are missing value codes! (1) The variable "lasttm" takes the value 0 prior to randomization, and after administration of study drug is stopped. (2) All patients are on placebo for months 0, 1, 2, and 3. (3) The S+ function "julian" can be used to convert date information (but you should be fine with month for this analysis).