Transport Effects in a Microchemical Reactor

Introduction

What are microchemical reactors?

Microchemical reactors, or microreactors, are miniaturized reaction systems containing one or more reaction channels with sub-centimeter dimensions. Microreactors enable the introduction of new reaction procedures in chemistry, molecular biology and pharmaceutical chemistry. They also offer tremendous opportunities in the traditional chemical engineering sub-disciplines of catalysis, transport phenomena, and reaction engineering. Some examples of microreactors are shown below.


Source: Klavs F. Jensen, AIChE Journal 1999, Vol. 45, No. 10, pp2051

How to manufacture microreactors?

Generally, microreactors are produced by micro-fabrication or micro-lamination. Microreactors are normally produced from metals, glass, silicon, and ceramic, due to their chemical inertness and temperature stability.

 

Advantages of microreactors over large-scale processes:

1. Safer operation due to:

á        Quicker transport process

á        On-site or on-demand production

á        Novel reaction conditions

2. Larger surface area to volume ratio, and new catalyst testing with tiny amount of catalyst

3. Better control of product distribution

 

1. Different reactions, such as ammonia oxidation, hydrogen and oxygen on platinum, aliphatic alcohol to aldehydes, and so on.

2. Biological applications, such as polymerase chain reaction (PCR), kinetics of bacterial reaction, T-sensor, and nuclei acid synthesis and detection.

 

Commercial use of microreactors:

Microreactors are attracting more and more interests, due to many important and unique features. However, the scale-up problem must be overcome before the commercial use. Numbering-up of microreactors should be about to lead to a cost-effective production of amounts of chemicals not profitable on a larger scale. It is believed that microreactors will become commercial in the near future.



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