"Effectiveness of Treatment for Chronic PTSD"
This a five year NIMH funded randomized clinical trial at the University of Washington and University Hospitals Cleveland, Case Western Reserve University, investigating the role of choice in treatment outcome, and comparing two effective treatments for posttraumatic stress disorder (PTSD), prolonged exposure and sertraline. We are currently enrolling participants and will continue through 2008.
UWCATS)
University of Washington Center for Anxiety & Traumatic
Stress
“People can’t be trusted—the world isn’t
safe.”
“I have no control. I am going crazy.”
“My life will never be the same.”
“It was my fault—I should have known what would
happen.”
Sexual
assault
Childhood
sexual assault
Assault
with a weapon
Combat
Armed
robbery
Car
accident
Recurrent
thoughts of the trauma
Intense
feelings of fear and anxiety
Nightmares
Sweating,
racing heart, or hot or cold flashes when reminded of the trauma
Avoiding
situations, people, or thoughts associated with the trauma
Feelings
of detachment from others
Difficulty
experiencing strong emotions (feeling numb)
Jumpiness
or a tendency to be easily startled
If you qualify to be a
part of this research study at either site, you will receive:
|
|
Psychotherapy (prolonged exposure) |
|
90 minute weekly sessions, including support and
education about common reactions to
trauma |
OR |
Medication |
|
30-minute weekly
sessions, including support and education about common reactions to
trauma |
|
|
Specifics on the treatments:
Prolonged exposure (PE) is a 10 session individual therapy that has been shown to be effective in the treatment of PTSD. If you receive this treatment for PTSD, you will meet once a week with your therapist for 60 to 90 minutes. You will not receive medication for your PTSD symptoms. During this treatment, you will be encouraged to confront the memory of your trauma through repeatedly telling the story to your therapist and to confront things in your life that your are avoiding because they make you afraid (e.g., driving in a car, walking on the street at night). In this program, you will be assigned "homework" to encourage you to practice in life the things you learn in therapy.
Zoloft (sertraline) is an antidepressant that has been shown to be effective in the treatment of PTSD. You will take up to 200 mg of Zoloft daily for 10 weeks. You will be seen weekly by a psychiatrist who will offer general encouragement and support, monitor your response to medication, and record any side effects you are experiencing. Your medication will be adjusted according to a dosing schedule and based on your study doctor's medical judgment. At the end of 10 weeks you will have the choice of tapering (reducing) your medication gradually to minimize the chance of withdrawal symptoms with medication discontinuation or staying on the medication for up to 24 months.
Guthrie Annex II, 2nd Floor |
Box
351525
University of Washington
| Seattle, WA 98195
|
Lori A. Zoellner, Ph.D. |
Sally Moore, M.S. |
|
Peter Roy-Byrne, M.D. |
Joyce Bittinger,
B.S. |
|
Joshua McDavid, M.D. |
Michele Bedard,
B.S. |
|
Afsoon Eftekhari, Ph.D. |
Helen Miller, B.S. |
From I-5:
Take the 45th street exit (UW)
Go east on 45th street to 15th
avenue and turn right on 15th
At 40th street, turn left onto
campus (Gate 5)
At the gatehouse, tell the attendant that you have an appointment in Guthrie Annex II
By
Bus:
From routes 43, 44, 45, 46, 48,
75, 167, 271, 272, 277, and 373, exit the bus at 15th avenue and 40th
street (Gate 5)
Take the pathway from the SE corner
of the intersection to the C-8 parking lot and Guthrie Annex II
Guthrie Annex II is the two-story,
grayish building at the south end of the C-8 parking lot