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Department of Bioengineering, Box 352255, University of Washington, Seattle, WA 98195, USA |
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Department of Bioengineering, Box 352255, University of Washington, Seattle, WA 98195, USA |
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EMPLOYMENT:
EDUCATIONAL INSTITUTION, DEGREE, YEARS
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Princeton University |
A. B., Biochemistry, 1975 |
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University of Oregon |
Ph.D., Chemistry, 1980 |
ISSUED PATENTS
PUBLICATIONS:
1. Polarized resonance Raman spectroscopy of beta-carotene in phospholipid monolayers, Yager, P., B.A. Thesis, Department of Biochemistry, Princeton University (1975)
2. A novel mechanism for the Na-K ATPase, Yager, P., J. Theor. Biol., 66, 1-11 (1977)
3. Interpretation of biomembrane structure by Raman difference spectroscopy, Gaber, B.P., Yager, P. and Peticolas, W.L., Biophysical Journal, 21, 161-207 (1978)
4. Deuterated phospholipids as non-perturbing components for Raman studies of biomembranes, Gaber, B.P., Yager, P. and Peticolas, W.L., Biophysical Journal, 22, 191-207 (1978)
5. Conformational non-equivalence of chains 1 and 2 of dipalmitoyl phosphatidylcholine as observed by Raman spectroscopy, Gaber, B.P., Yager, P. and Peticolas, W.L., Biophysical Journal, 24, 677-688 (1978)
6. Applications of Raman spectroscopy to biomembrane structure, Gaber, B.P., Yager, P. and Peticolas, W.L., pp. 241-260 in Infrared and Raman Spectroscopy of Biological Molecules, T.M. Theophanides, ed., D. Reidel Pub. Co., Holland (1979)
7. Statistical mechanical analysis of Raman spectroscopic order parameter changes in pressure-induced lipid bilayer phase transitions, Yager, P. and Peticolas, W.L., Biophysical Journal, 31, 359-370 (1980)
8. Raman spectroscopic studies of the structure of phases of aqueous phosphatidylcholine dispersions and the kinetics of conversions between them, Yager, P., Ph.D. Dissertation, Department of Chemistry, University of Oregon, June, 1980
9. Thermodynamic properties of mixtures of deuterated and undeuterated dipalmitoyl phosphatidylcholines, Klump, H.H., Gaber, B.P., Peticolas, W.L., and Yager, P., Thermochimica Acta, 48, 361-366 (1981)
10. The kinetics of the main phase transitions of aqueous dispersions of phospholipids induced by pressure jump and monitored by Raman spectroscopy, Yager, P. and Peticolas, W.L., Biochimica et Biophysica Acta, 688, 775-785 (1982)
11. Changes in size and shape of liposomes undergoing chain melting transitions as studied by optical microscopy, Yager, P., Sheridan, J.P., and Peticolas, W.L., Biochimica et Biophysica Acta, 693, 484-491 (1982)
12. Destabilization of lipid non-bilayer phase by high pressure, Yager, P. and Chang, E.L. Biochimica et Biophysica Acta, 731, 491-494 (1983)
13. Encapsulation of hemoglobin in phospholipid vesicles, Gaber, B.P., Yager, P., Sheridan, J.P. and Chang, E.L., FEBS Letters, 153, 285-288 (1983)
14. Effect of high pressure on a lipid non-bilayer phase, Chang, E.L. and Yager, P., Molecular Crystals and Liquid Crystals, 98, 125-129 (1983)
15. The secondary structure of acetylcholine receptor reconstituted in a single lipid component as determined by Raman spectroscopy, Yager, P., Chang, E.L., Williams, R.W. and Dalziel, A.W., Biophysical Journal, 45, 26-28 (1984)
16. Formation of tubules by a polymerizable surfactant, Yager, P. and Schoen, P.E., Molecular Crystals and Liquid Crystals, 106, 371-381 (1984)
17. Spectroscopic studies of polymerized surfactants: 1,2-bis(10,12-tricosadiynoyl)-sn-glycero-3-phosphocholine, Schoen, P.E. and Yager, P., Journal of Polymer Science, Polymer Physics Edition, 23, 2203-2216 (1985)
18. Structure of lipid tubules formed from a polymerizable lecithin, Yager, P., Schoen, P.E., Davies, C., Price, R., and Singh, A., Biophysical Journal, 48, 899-906 (1985)
19. Spectroscopic studies of a diacetylenic surfactant, Schoen, P.E., Yager, P. and Priest, R.G., in Polydiacetylenes: Synthesis, Structure, and Electronic Properties, Bloor, D. and Chance, R.R., Eds.., NATO Advance Study Institute Series, Martinus Nijhoff, Dordrecht, the Netherlands (1985)
20. Tubule formation by heterobifunctional polymerizable lipids: synthesis and characterization, Singh, A., Price, R., Schnur, J.M., Schoen, P.E., and Yager, P., Polym. Preprints, 27:393-394 (1986)
21. Functional reconstitution of a membrane protein in a diacetylenic polymerizable lecithin, Yager, P., Biosensors, 2, 363-373 (1986)
22. Membranes, Yager, P. and Gaber, B.P., in Biological Applications of Raman Spectroscopy: Vol. 1--Raman Spectra and The Conformations of Biological Macromolecules, Spiro, T.G., ed., John Wiley, New York. pp. 203-261 (1987).
23. Orientation of lipid tubules by a magnetic field, Rosenblatt, C., Yager, P., and Schoen, P.E., Biophys. J., 52, 295-301 (1987)
24. Helical and tubular microstructures formed by polymerizable phosphatidylcholines, Georger, J., Price, R., Singh, A., Schnur, J.M., Schoen, P.E. and Yager, P., J. Am. Chem. Soc. 109, 6169-6175 (1987).
25. Progress report on the fabrication of an acetylcholine receptor-based biosensor, Dalziel, A.W., Georger, J., Price, R.R., Singh, A., and Yager, P., in The Proceedings of the Membrane Protein Symposium, S.G. Goheen, Ed., BioRad Laboratories , Richmond CA, (1987)
26. Synthesis and characterization of positional isomers of 1,2-bis heptacosadiynoyl phosphocholines, Singh, A., Singh, B.P., Gaber, B.P., Burke, T., Yager, P., Schoen, P.E. and Schnur, J.M., pp. 467-476 in Surfactants in Solution, L.K. Mittal, Ed., New York, (1987)
27. Order in diacetylenic microstructures, Schoen, P.E., Yager, P., Sheridan, J.P., Price, R.R., Schnur, J.M., Singh, A., Rhodes, D.G. and Blechner, S.L., Mol. Cryst. Liq. Cryst., 153, 357-366 (1987)
28. Lipid-based tubule microstructures, Schnur, J.M, Price, R, Schoen, P.E., Yager, P., Calvert, J.M., Georger, J., and Singh, A., Thin Solid Films, 152, 181-206 (1987).
29. The mechanism of formation of tubules from liposomes, Yager, P., Schoen, P.E., Price, R., Schnur, J.M., Singh, A., and Rhodes, D.G., Chem. Phys. Lipids., 46, 171-179 (1988).
30. Light scattering investigation of electric field alignment of phospholipid tubules, Li, Z., Rosenblatt, C., Yager, P., and Schoen, P.E., Biophys. J., 54, 289-294 (1988).
31. Development of membrane-based biosensors: measurement of current from photocycling bacteriorhodopsin on patch clamp electrodes, Yager, P., in Biotechnological Applications of Lipid Microstructures, Volume 238, B.P. Gaber, ed., Plenum, Inc., (1988)
32. Lateral phase separation based on chirality in a polymerizable lipid and its influence on formation of tubular microstructures, Singh, A., Georger, J., Price, R.R., Burke, T., Schoen, P.E., and Yager, P., Chem. Phys. Lipids, 47, 135-148 (1988).
33. Fabrication of key components of a receptor-based biosensor, Ligler, F.S., Fare, T.L., Seib, E.E., Smuda, J.W., Singh, A., Ahl, P. , Ayers, M.E., Dalziel, A.W., and Yager, P., Med. Instrumentation, 22, 247-256 (1988).
34. Structure of polymerizable lipid bilayers, I -- 1,2-bis(10,12-tricosadiynoyl)-sn-phosphocholine, a tubule-forming phosphatidylcholine, Rhodes, D.G., Blechner, S.L., Yager, P. Schoen, P.E., Chem. Phys. Lipids, 49, 39-47 (1988)
35. Entrapment of 6-carboxyfluorescein within cylindrical phospholipid microstructures, Burke, T.G., Singh, A., and Yager, P., Ann. N.Y. Acad. Sci., 507, 330-333 (1988)
36. Electric field manipulation of phospholipid tubules: Optical birefringence measurements, Woods, D.M., Li, Z., Rosenblatt, C., Yager, P., and Schoen, P.E., Mol. Cryst. Liq. Cryst., 167, 1-6 (1989)
37. An optical method for detecting anesthetics and other lipid-soluble compounds, Merlo, S., Burgess, L.W., and Yager, P., Sensors and Actuators, A21-A23, 1150-1154 (1990)
38. Optical method for monitoring the concentration of general anesthetics and other small organic molecules--an example of phase transition sensing, Merlo, S. and Yager, P., Anal. Chem., 62, 2728-2735 (1990)
39. Electrostatic interactions within helical structures of chiral lipid bilayers, Chappell, J.S. and Yager, P., Chemical Physics, 150, 73-79 (1991).
40. Sensore a fibre ottiche per il monitoraggio dell'anestesia generale, Merlo, S., Yager, P., and Burgess, L.W., in Proceedings of Fotonica '91, 2° Cenvegno Nazionale Sull Techniche Fotoniche per L'Informazione, Simione, Italy, March 1991 (1991)
41. A model for crystalline order within helical and tubular structures of chiral bilayers, Chappell, J.S., and Yager, P., Chem. Phys. Lipids, 58, 253-258 (1991).
42. Electrolyte effects on bilayer tubule formation by a diacetylenic phospholipid, Chappell, J.S., and Yager, P., Biophysical Journal, 60, 1-14 (1991)
43. Structure of polymerizable lipid bilayers III: two heptacosadiynoyl phosphatidylcholine isomers, Blechner, S.L., Morris, W., Schoen, P.E., Yager, P., Singh, A. and Rhodes, D.G., Chem. Phys. Lipids, 58, 41-54.(1991)
44. Development of a fiber optic sensor for detection of general anesthetics and other small organic molecules, Merlo, S., Yager, P. and Burgess, L.W., in Advanced Methods of Pharmacokinetic and Pharmacodynamic Systems Analysis: David Z D'Argenio, ed., Plenum Press, New York (1991)
45. Detection of general anesthetics using a fluorescence-based sensor: incorporation of a single-fiber approach, Abrams, S.B., Fleharty, H.L., and Yager, P., SPIE Proceedings 1420, 13-21, (1991)
46. Preparation and properties of macroporous poly(n-isopropylacrylamide) hydrogels, Wu, X.S., Hoffman, A.S., and Yager, P., Polymer Preprints 32(3), 463-464, (1991).
47. When lipid bilayers won't form liposomes: tubules, helices, and cochleate cylinders, Yager, P., Chappell, J, and Archibald, D.D., in Membrane Structure and Function: The State of the Art--Proceedings of the Indo-U.S. Workshop, Gaber, B.P. and Easwaran, K.R.K., Eds., pp. 1-19, Adenine Press, (1992)
48. Formation of mineral microstructures with a high aspect ratio from phospholipid bilayers, Chappell, J.S., and Yager, P., J. Mat. Sci. Lett., 11, 633-636, (1992).
49. Microstructural polymorphism in bovine brain galactocerebrosides and its subfractions, Archibald, D.D., and Yager, P., Biochemistry, 31, 9045-9055 (1992)
50. Detection of volatile and soluble general anesthetics using a fluorescence-based fiber optic sensor: Recent progress in chemical sensitivity and noise sources, Yager, P. and Abrams, S.B., SPIE Proceedings, 1648, 51-62 (1992)
51. Evaluation of signal reabsorption and sample heating in NIR-Raman measurements, Archibald, D.D., and Yager, P., Applied Spectroscopy, 46, 1613-1620 (1992)
52. Conjugation of phosphatidylethanolamine to poly-(N-isopropylacrylamide) for potential use in liposomal drug delivery systems, Wu, X.S., Hoffman, A.S., and Yager, P., Polymer, 33(21), 4659-4662 (1992).
53. Synthesis and characterization of thermally reversible macroporous poly(N-isopropylacrylamide) hydrogels, Wu, X.S., Hoffman, A.S., and Yager, P., J. Polym. Sci.: Pt. A.: Polym. Chem., 30, 2121-2129 (1992).
54. Perturbation of the chain melting transition of DPPC by galactose, agarose and Laurdan as determined by differential scanning calorimetry, Abrams, S.B. and Yager, P., Biochim. Biophys. Acta, 1146, 127-135 (1993)
55. Synthesis of and insulin release from erodible poly(N-isopropylacrylamide)-phospholipid composites, Wu, X.S., Hoffman, A.S., and Yager, P., J. Intell. Mtls. Syst. & Struct., 4, 202-209 (1993)
56. Influence of pH on the precursors of phospholipid tubules in methanolic solution, Lu, M.-H., Rosenblatt, C., and Yager, P., Chem. Phys. Lipids, 65, 77-84 (1993)
57. Use of a visible fluorescence dye in a fiberoptic sensor to detect general anesthetics, Abrams, S.B. and Yager, P., SPIE Proceedings, 1885, 62-71 (1993)
58. Effect of conjugation of phospholipid to poly(N-isopropylacrylamide) on its critical solution temperature, Wu, X.S., Hoffman, A.S., and Yager, P., Makromol. Chem. Rapid Commun., 14, 309-314 (1993)
59. Raman spectroscopic analysis of the secondary structure of spider silk fiber, Gillespie, D.B. , Viney, C., and Yager, P., in Silk Polymers: Materials Science and Biotechnology, D. Kaplan, et al., Editor. American Chemical Society: Washington, DC. pp. 155-167 (1994)
60. Fiber optic sensor for general anesthetics based on Raman spectroscopy, MacDonald, H.L, Liu, H., and Yager, P., SPIE Proceedings, 2131, 514-524 (1994)
61. Structural investigation of (Ad II)26 fiber, a novel bioengineered material based on a viral spike protein, Gillespie, D.B, Thiel, B.L., Trabbic, K.A, Viney, C, and Yager, P., Macromolecules, 27, 6177-6182 (1994)
62. Modeling success and failure of Langmuir-Blodgett transfer of phospholipid bilayers to silicon dioxide, Osborn, T.D. and Yager, P., Biophys. J., 68, 1364-1373 (1995)
63. Modeling of optical bending losses in multimode waveguides by ray tracing, Liu, H. and Yager, P. SPIE Proceedings, 2396, 120-129 (1995)
64. Application of multiplicative signal correction (MSC) to Raman spectra for use in an anesthetic sensor, Parnell, J.R. and Yager, P. SPIE Proceedings, 2388, 481-492 (1995)
65. Freely suspended solvent-free lipid bilayers by Langmuir-Blodgett transfer to micromachined apertures in silicon, Osborn, T.D. and Yager, P., Langmuir, 11, 8-12 (1995)
66. Silicon microchannel optical flow cytometry, Altendorf, E., Yager, P., Iverson, E., Yu, H., Osborn, T., Proceedings of the CHI Microfabrication Technology for Research and Diagnostics Conference, San Francisco, Sept. 28-29 (1995).
67. Liposome-based optical sensor for general anesthetics: Implementation of phase transition sensing, Yager, P., Abrams, S.B., and Merlo, S., in Biophysics of Organized Lipid Membranes for Applications in Chemical Analysis; Current Topics in Biophysics, Vol. 3 229-270, Krull, U.J., Ed., Iasi University Press, Iasi, Romania, (1995)
68. Sensors, Yager, P., in Biomaterials Science: An Introductory Text, Ratner, B.D. and Hoffman, A.S., Eds. Academic Press, Inc., Orlando, (1996)
69. Low Reynolds number micro-fluidic devices, Brody, J.P. and Yager, P., Proceedings Hilton Head MEMS conference, Solid-State Sensor and Actuator Workshop, 105-108, (1996).
70. A planar microfabricated fluid filter , Brody, J.P., Osborn, T.D., Forster, F.K. and Yager, P., (Proceedings of Transducers '95), Sensors and Actuators A (Physical), A54 (1-3), 704-708, (1996).
71. Optimal design of a microfabricated diffusion-based extraction device, Holl, M.R., Galambos, P., Forster, F.K., Brody, J.P., Afromowitz, M.A., and Yager, P., Proceedings of 1996 ASME Meeting ASME DSC59, 189-195 (1996)
72. Feasibility study for the measurement of oxyhemoglobin using whole blood without pretreatment, Wu, C., Kenny, M.A., Huang, M., Afromowitz, M.A., and Yager, P., Clinical Chemistry 42:S283, (1996).
73. Biotechnology at low Reynolds numbers, Brody, J.P., Yager-P., Goldstein, R.E., and Austin, R.H., Biophysical Journal. 71 (6), 3430-3441, (1996).
74. Optical flow cytometry utilizing microfabricated silicon flow channels, Altendorf, E., Iverson, E., Schutte, D., Weigl, B., Osborn, T.D., Sabeti, R., and Yager, P. SPIE Proceedings, Vol. 2678, 267 (1996).
75. Diffusion-based optical chemical detection in silicon flow structures, Weigl, D.H., Holl, M.R., Schutte, D., Brody, J., Yager, P., Analytical Methods & Instrumentation, Proceedings of µTAS '96, 174-184, (1996).
76. Rapid sequential chemical analysis using multiple fluorescent reporter beads, Weigl, B.H., Huang, M.C., van den Engh, G., Kaiser, R., Altendorf, E., Afromowitz, M., Yager, P., Analytical Methods & Instrumentation, Proceedings of µTAS '96, 255, (1996).
77. Fluorescent reporter beads for chemical analysis, Weigl, B.H., Huang, M.C., van den Engh, G., Kaiser, R., Altendorf, E., Afromowitz, M., Yager, P., Analytical Methods and Instrumentation, Proceedings of µTAS '96, pp. 174-184, International Journal of New Techniques and Applications, Basel, Switzerland (1996).
78. Particle discrimination capabilities of a flow cytometer utilizing microfabricated flow channels, Altendorf, E., Zebert, D., Yager, P., Journal of Microelectromechanical Systems, July 26 (1996).
79. Silicon-microfabricated diffusion-based optical chemical sensor, Weigl, B.H. and Yager, P., (Conference Proceedings Europtrode III, 1996) Sensors and Actuators B (Chemical), B39 (1-3), 452-457 (1997).
80. Patterned sol-gel structures by micro molding in capillaries, Lochhead, M.J., Yager, P., Materials Research Society Symposium Proceedings. Vol. 444. 105-110, (1997).
81. Oxyhemoglobin measurement of whole blood specimens in a silicon microfabricated cuvette, Wu, C., Holl, M., Kenny, M.A., Yager, P., SPIE Proceedings, Micro- and Nanofabricated Electro-Optical Mechanical Systems for Biomedical and Environmental Applications, 2978, 155-164 (1997).
82. Development of silicone waveguides for use in a Raman spectroscopy-based sensor for general anesthetics, Parnell, J.R., Schutte, D. and Yager, P., SPIE Proceedings, 2976, 20-29 (1997)
83. Prominent microscopic effects in microfabricated fluid analysis systems, Brody, J.P., Kamholz, A.E., Yager, P., SPIE Proceedings, Micro- and Nanofabricated Electro-Optical Mechanical Systems for Biomedical and Environmental Applications, 2978, 103-110, (1997).
84. Microfabricated interlock system for precision alignment, Sabeti, R., Holl, M.R., Altendorf, E.A., and Yager, P., SPIE Proceedings, Micro- and Nanofabricated Electro-Optical Mechanical Systems for Biomedical and Environmental Applications, 2978, 180-185, (1997).
85. Zero-order interfacial enzymatic degradation of phospholipid tubules, Carlson, P.A., Gelb, M.H., and Yager, P., Biophysical Journal, 73(1), 230-239 (1997).
86. Formation of high axial ratio microstructures from natural and synthetic sphingolipids, Goldstein, A.S., Lukyanov, A.N., Carlson, P., Yager, P., and Gelb, M.H., Chem. Phys. Lipids, 88, 21-36 (1997).
87. Diffusion-based extraction in a microfabricated device, Brody, J.P. and Yager, P., Sensors and Actuators A (Physical), A58(1), 13-18 (1997)
88. Multi-component micro-patterned sol-gel materials by capillary molding, Lochhead, M.J. and Yager, P., Sol-Gel Optics IV, SPIE Proc. Ser. 3136, 261-266 (1997)
89. Differential blood cell counts obtained using a microchannel based flow cytometer, Altendorf, E., Zebert, D., Holl, M., Yager, P., Proc. Transducers '97, 531-534, vol.1 (1997).
90. Comparative structural characterization of naturally and synthetically-spun fibers of Bombyx mori fibroin, Trabbic, K.A. and Yager, P., Macromolecules, 31(2), 462-471 (1998).
91. Formation of high axial ratio microstructures from peptides modified with glutamic acid dialkyl amides, Lee, K.J., Lukyanov, A.N., Gelb, M.H., and Yager, P., Biochim. Biophys. Acta, 1371, 168-184 (1998).
92. Integration of microelectrodes with etched microchannels for in-stream electrochemical analysis, Darling, R.B., Kriebel, J., Mayes, K.J., Weigl, B.H., and Yager, P., in Micro Total Analysis Systems '98, D. J. Harrison and A. van den Berg, eds. Kluwer Academic Publishers, Dordrecht, 105-108 (1998)
93. Applying microfluidic chemical analytical systems to imperfect samples, Yager, P., Bell, D., Brody, J.P., Qin, D., Cabrera, C., Kamholz, A., and Weigl, B.H., in Micro Total Analysis Systems '98, D. J. Harrison and A. van den Berg, eds., Kluwer Academic Publishers, Dordrecht, 207-212 (1998)
94. Simultaneous self-referencing analyte determination in complex sample solutions using microfabricated flow structures (T-Sensors), Weigl, B.H., Kriebel, J., Mayes, K.J., Yager, P. Wu, C.-C., Holl, M., Kenny, M. and Zebert, D., in Micro Total Analysis Systems '98, D. J. Harrison and A. van den Berg, eds., Kluwer Academic Publishers, Dordrecht, 81-84 (1998)
95. Design of microfluidic sample preconditioning systems for detection of biological agents in environmental samples, Yager, P., Afromowitz, M.A., Bell, D., Forster, F.K., Brody, J.P., Qin, D., Cabrera, C., Holl, M., Kamholz, A., and Weigl, B.H., SPIE Proceedings, 3515, 252-259 (1998)
96. Feasibility study of the spectroscopic measurement of oxyhemoglobin using whole blood without pre-treatment, Wu, C., Kenny, M.A., Huang, M.C., Afromowitz, M.A., and Yager, P., Analyst, 123(3), 477-481 (1998)
97. Microfluidic diffusion-based separation and detection, Weigl, B.H. and Yager, P., Science, 283(5400), 346-347 (1999)
98. Quantitative analysis of molecular interaction in a microfluidic channel: the T-sensor, Kamholz, A.E., Weigl, B.H., Finlayson, B.A. and Yager, P., Analytical Chemistry, 71(23), 5340-5347 (1999)
99. Microfabricated silicon flow-cell for optical monitoring of biological fluids, Chau, L.-K., Osborn, T., Wu, C.-C., and Yager, P., Analytical Sciences, 15, 721-724 (1999)
100. Protection of lipopeptide from proteolytic cleavage by self-assembly into lipid tubules. Model sustained release drug delivery system, Lee, K.C., Yager, P., and Gelb, M.H., Langmuir, 15 (17), 5500-5508 (1999).
101. Whole blood diagnostics in standard gravity and microgravity by use of microfluidic structures (T-sensors), Weigl, B.H., Kriebel, J., Mayes, K.J., Bui, T. and Yager, P., Mikrochimica Acta, 131, 75-83 (1999)
102. A microfluidic sedimentation particulate capture device with internal degassing membranes, Holl, M.M., Macounova, K., and Yager, P., in Micro Total Analysis Systems 2000, van den Berg, Olthuis and Bergveld, eds., Kluwer Academic Publishers, Dordrecht, 15-18 (2000).
103. Analytical devices based on transverse transport in microchannels, Yager, P., Cabrera, C., Hatch, A., Hawkins, K., Holl, M., Kamholz, A., Macounova, K., and Weigl, B.H., in Micro Total Analysis Systems 2000, van den Berg, Olthuis and Bergveld, eds., Kluwer Academic Publishers, Dordrecht, 319-322 (2000)
104. Generation of natural pH gradients in microfluidic channels for use in isoelectric focusing, Macounová, K., Cabrera, C.R., Holl, M.R. and Yager, P., Analytical Chemistry, 72(16), 3745-3751 (2000).
105. Use of isoelectric focusing for sample preconditioning in a microfluidic electrochemical flow cell, Cabrera, C.R., Macounová, K., Holl, M.R., and Yager, P., Proceedings of the IEEE 1st Annual Conference on Microtechnology in Medicine and Biology, Lyon France, October, 2000, D. Beebe, Ed.,IEEE Press (2000)
106. Theoretical analysis of molecular diffusion in pressure-driven laminar flow in microfluidic channels, Kamholz, A.E. and Yager, P., Biophysical Journal, 80, 155-160 (2001)
107. Formation of natural pH gradients in a microfluidic device under flow conditions: Model and experimental validation, Cabrera, C.R., Finlayson, B.A., and Yager, P., Analytical Chemistry, 73(3), 658-666 (2001)
108. Continuous concentration of bacteria in a microfluidic flow cell using electrokinetic techniques, Cabrera, C.R. and Yager, P., Electrophoresis, 22(2), 355-362 (2001)
109. A rapid diffusion immunoassay in a T-Sensor, Hatch, A., Kamholz, A.E., Hawkins, K.R., Munson, M.S., Schilling, E.A., Weigl, B.H. and Yager P., Nature Biotechnology, 19(5), 461- 465 (2001)
110. The relationship between the structure of the headgroup of sphingolipids and their ability to form complex high axial ratio microstructures, Goldstein, A.S., Gelb, M.G. and Yager, P., Chem. Phys. Lipids., 109(1), 1-14 (2001)
111. Continuous and highly variable rate controlled release of model drugs from sphingolipid-based complex high axial ratio microstructures, Goldstein, A.S., Yager, P. and Gelb, M.H., J. Controlled Release, 70(1-2), 125-138 (2001)
112. Optical measurement of transverse molecular diffusion in a microchannel, Kamholz, A.E., Schilling, E.A. and Yager, P., Biophysical Journal, 80(4), 1967-1972 (2001)
113. Concentration and separation of proteins in microfluidic channels on the basis of transverse IEF, Macounová, K., Cabrera, C.R., and Yager, P., Analytical Chemistry, 73(7), 1627-1633 (2001)
114. A ferrofluidic magnetic micropump, Hatch, A., Kamholz, A.E., Holman, G., Yager, P., and Böhringer, K.F., Journal of MEMS, 10(2), 1-7 (2001)
115. Mapping of pH gradients in microfluidic electrokinetic devices, Cabrera, C.R., and Yager, P., in Micro Total Analysis Systems 2001, Ramsay, J.M. & van den Berg, A., eds., Kluwer Academic Publishers, Dordrecht, 105-106 (2001)
116. Cell lysis and protein extraction in a microfluidic device with detection by a fluorogenic enzyme assay, Schilling, E.A., Kamholz, E.A., and Yager P., in Micro Total Analysis Systems 2001, Ramsay, J.M. & van den Berg, A., eds., Kluwer Academic Publishers, Dordrecht, 265-267 (2001)
117. Diffusion immunoassay in polyacrylamide hydrogels, Hatch, A. and Yager, P., in Micro Total Analysis Systems 2001, Ramsay, J.M. & van den Berg, A., eds., Kluwer Academic Publishers, Dordrecht, 571-572 (2001)
118. Testosterone delivery using glutamide based complex high axial ratio microstructures, Goldstein, A.S., Amory, J.K., Martin, S.M., Vernon, C., Matsumoto, A.M., and Yager, P., Bioorganic and Medicinal Chemistry, 9(11), 2819-2825 (2001).
119. Molecular diffusive scaling laws in pressure-driven microfluidic channels: deviation from one-dimensional Einstein approximations, Kamholz, A.E. and Yager, P. Sensors and Actuators B, 82(1), 117-121 (2002).
120. Cell lysis and protein extraction in a microfluidic device with detection
by a fluorogenic enzyme assay, Schilling, E.A., Kamholz, A.E., and Yager, P., Analytical Chemistry, 74(8), 1798-1804 (2002)
121. Diffusion immunoassay for protein analytes, Hawkins, K.R., Hatch, A.,
Chang, H., and Yager, P. in Proceedings of Microtechnologies in Medicine
and Biology, Madison, WI, IEEE Press, 535-540, (2002)
122. Passive electrophoresis in microchannels using liquid junction potentials.
Munson, M.S., Cabrera, C.R, and Yager, P. Electrophoresis,
23, 2642-2652 (2002).
123. Wavelength-tunable surface plasmon resonance microscope, Fu, E., Foley,
J., and Yager, P., Review of Scientific Instruments, 74(6),
3182-3184 (2003)
124. A smart microfluidic affinity chromatography matrix composed of poly(N-isopropylacrylamide)-coated
beads, Malmstedt, N., Yager, P., and Stayton, P., Analytical Chemistry,
75(13), 2943-2949 (2003)
125. Nonlinear decay of background fluorescence in polymer thin-films - a survey
of materials and how they can complicate fluorescence detection in µTAS,
Hawkins, K.R. and Yager, P., Lab
on a Chip, 3(4), 255-259 (2003)
126. Transverse diffusion in microfluidic systems, Yager, P., in Lab-on-a-chip: Chemistry in Miniaturized Synthesis and Analysis Systems, R.E. Oosterbroek, R.E., and van den Berg, A., Eds., (2003)
127. Analysis of molecular binding to human serum albumin using a T-sensor, A. Hatch, E. Garcia, and P. Yager, in Micro Total Analysis Systems 2003, Northrup, M.A., Jensen, K.F., and Harrison, D.J, eds., Mesa Monographs, 1215-1218 (2003)
128. T-sensor generated refractive index gradients: calibration of an SPR microscope, J. Foley, E. Fu, and P. Yager, in Micro Total Analysis Systems 2003, Northrup, M.A., Jensen, K.F., and Harrison, D.J, eds., Mesa Monographs, 967-970 (2003)
129. Capture-and-release concentration of bacteria using free-flow zone electrophoresis, K.J Halle, J.J. Li, M.S. Munson, J. Monteith, E. Guzman, S. Feather, J. Verba, Q. Porter, V. Kenning, A.E. Kamholz, B.H. Weigl, P. Saltsman, R. Bardell, and P. Yager, in Micro Total Analysis Systems 2003, Northrup, M.A., Jensen, K.F., and Harrison, D.J, eds., Mesa Monographs, 559-562 (2003)
130. Modeling controlled release from cavities in microchannels, E. Garcia, F. Kusmanto, B. Finlayson, and P. Yager, in Micro Total Analysis Systems 2003, Northrup, M.A., Jensen, K.F., and Harrison, D.J, eds., Mesa Monographs, 551-554 (2003)
131. A novel microfluidic mixer based on successive lamination, M.S. Munson and P. Yager, in Micro Total Analysis Systems 2003, Northrup, M.A., Jensen, K.F., and Harrison, D.J, eds., Mesa Monographs, 495-498 (2003)
132. On the importance of quality control in microfluidic device manufacturing, M.R. Steedman, K.M. Lloyd, M.S. Munson, and P. Yager, in Micro Total Analysis Systems 2003, Northrup, M.A., Jensen, K.F., and Harrison, D.J, eds., Mesa Monographs, 1069-1072 (2003)
133. Simple quantitative optical method for monitoring the extent of mixing applied to a novel microfluidic mixer, Munson, M.S. and Yager, P., Analytica Chimica Acta, 501(1), 63-71 (2004)
134. Controlled microfluidic reconstitution of functional protein from an anhydrous storage depot, Garcia, E., Kirkham, J. R., Hatch, A.V, Hawkins, K.R. and Yager, P., Lab on a Chip, 4, 78-82 (2004)
135. Characterization of a wavelength-tunable surface plasmon resonance microscope,
Fu, E., Chinowsky T., Foley, J., Weinstein J., and Yager, P., Review
of Scientific Instruments, 75(7), 2300-2304 (2004).
136. Diffusion-based analysis of molecular interactions in microfluidic devices,
Hatch, A., Garcia, E. and Yager, P., IEEE Proceedings, 92(1),
126-139 (2004)
137. Suppression of non-specific adsorption using sheath flow, Munson, M. S.,
Hasenbank, M. S., Fu, E. and Yager, P., Lab on a Chip, 4, 438-445
(2004)
138. Parallel microfluidic processing of protein assembly quantified using SPR
microscopy, Blaylock, M., Fu, E. and Yager, P., Micro Total Analysis Systems
2004, Vol. 1., Laurell, Nilson, Jensen, Harrison and Kutter, Eds., RSC
Press, 354-356 (2004)
139. The aggregation of multivalent immune complexes expands the useful analyte
size range of the diffusion immunoassay, Hawkins, K.R. and Yager, P., Micro
Total Analysis Systems 2004, Vol. 1., Laurell, Nilson, Jensen, Harrison
and Kutter, Eds., RSC Press, 129-131 (2004)
140. Diffusion based analysis in a sheath flow microchannel: the sheath flow
T-sensor, Munson, M. S., Hawkins, K. R., Hasenbank, M. S., and Yager, P., Lab
on a Chip, 5, 856-862 (2005)
141. Lab-on-a-chip and fluorescence sensing on the microscale, Chang, H. N.,
Hatch, A. V., Hawkins, K. R. and Yager, P., in Fluorescence Sensors and
Biosensors, R. B. Thompson, ed., ISBN 0-8247-2737-1, CRC Press, Boca Raton,
FL, c.400 pp (2005)
142. Transverse transport in microsystems: theory and applications, Yager, P.,
Cabrera, C. and Kamholz, A.E., in Separation Methods in Microanalytical
Systems, Jörg P. Kutter and Yolanda Fintschenko, Eds., CRC Press,
Boca Raton, FL (2005)
143. Investigation of a rapid microfluidic surface plasmon resonance imaging
(SPRI) signal amplification scheme based on the rate of formation of an enzyme-catalyzed
precipitate, Hasenbank, M., Fu, E. and Yager, P., Micro Total Analysis Systems
2005, Vol. 1, Jensen, K.F., Han, J., Harrison, D.J. and Voldman, J., Eds.,
Transducer Research Foundation, Pubs., 485-487 (2005)
144. Rapid, parallel-throughput, multiple analyte immunoassays with on-board
controls on an inexpensive, disposable microfluidic device, Nelson, K.E., Foley,
J.O., Mashadi-Hossein, A., and Yager, P., Micro Total Analysis Systems 2005,
Vol. 2, Jensen, K.F., Han, J., Harrison, D.J. and Voldman, J., Eds., Transducer
Research Foundation, Pubs., 1000-1002 (2005)
145. Microfluidic high throughout screening of enzyme inhibition in a T-sensor,
Garcia, E. and Yager, P. Micro Total Analysis Systems 2005, Vol. 2,
Jensen, K.F., Han, J., Harrison, D.J. and Voldman, J., Eds., Transducer Research
Foundation, Pubs., 1443-1445 (2005)
146. A novel method of fluorescence detection and spectroscopy, Thariani, R.
and Yager, P., Micro Total Analysis Systems 2005, Vol. 2, Jensen, K.F.,
Han, J., Harrison, D.J. and Voldman, J., Eds., Transducer Research Foundation,
Pubs., 1470-1472 (2005).
147. Wavelength-dependent signal amplification potential of gold nanocage tags
for surface plasmon resonance (SPR) imaging, Fu, E., Foley, J. O., Chen, J.,
Wiley, B., Xia, Y. and Yager, P. Micro Total Analysis Systems 2005,
Vol. 2, Jensen, K.F., Han, J., Harrison, D.J. and Voldman, J., Eds., Transducer
Research Foundation, Pubs., 1510-1512 (2005).
148. Fully integrated multiplexed lab-on-a-card assay for enteric pathogens,
Weigl, B. H., Gerdes, J., Tarr, P., Yager, P., Dillman, L., Peck, R., Ramachandran,
S., Lemba, M., Kokoris, M., Nabavi, M., Battrell, F., Hoekstra, D., Klein, E.
J. and Denno, D. M.. Proc. SPIE, 6112, 11 pp. (2006)
149. Microfluidic diagnostic technologies for global public health, Yager, P.,
Edwards, T., Fu, E., Helton, K., Nelson, K., Tam, M. and Weigl, B., Nature
Insight, in press
150. One-dimensional surface plasmon resonance imaging system using wavelength
interrogation, Fu, E., Ramsey, S., Thariani, R., and Yager, P., Review of Scientific
Instruments, in press
151. Recirculating flow accelerates DNA microarray hybridization in a microfluidic
device, Lee, H.H., Smoot, J., McMurray, Z., Stahl, D.A., and Yager, P., Lab
on a Chip, in press
152. Lateral spread of an amplification signal using an enzymatic system on
a conductive surface, Hasenbank, M.S., Fu, E., and Yager, P., Langmuir,
in press.
153. Transport from embedded cavities for chemical distribution and surface
patterning applications, Garcia, E. L., Finlayson, B., and Yager, P., Sensors
and Actuators B: Chemical. Submitted
154. Compact surface plasmon resonance imaging system for saliva-based medical
diagnostics, Chinowsky, T. M., Grow, M. S., Johnston, K. S., Nelson, K., Edwards,
T., Fu, E., and Yager, P, Biosensors and Bioelectronics, submitted
1. Raman spectroscopic monitoring of the kinetics of pressure-jump induced phase transitions in phospholipid dispersions, Yager, P. and Peticolas, W.L., presented at VII International Biophysics Congress, Mexico City, August, 1981
2. Encapsulation of hemoglobin in phospholipid vesicles, Gaber, B.P., Yager, P., Sheridan, J.P. and Chang, E.L., Biophysical Journal, 37, 145a (1982), presented at Biophysical Society Meeting, Boston, February, 1982
3. Optical microscopy of multilamellar phospholipid dispersions undergoing phase transitions, Yager, P., Biophysical Journal, 37, 198a (1982), presented at Biophysical Society Meeting, Boston, February, 1982
4. The secondary structure of the reconstituted acetylcholine receptor as determined by Raman spectroscopy, Chang, E.L., Yager, P., Williams, R.W. and Dalziel, A.W., Biophysical Journal, 41, 65a (1983), presented at Biophysical Society Meeting, San Diego, February, 1983
5. The inverted hexagonal phase of phosphatidylethanolamine is antagonized by high pressure, Yager, P. and Chang, E.L., Biophysical Journal, 41, 347a (1983), presented at Biophysical Society Meeting, San Diego, February, 1983
6. Spectroscopic studies of polymerizable surfactants, Yager, P., Priest, R.G., and Schoen, P.E., presented at GTE Symposium on Order in Polymeric Materials, Waltham, Mass., August, 1983
7. Spectroscopic studies of polymerized surfactants, Schoen, P.E., Yager, P. and Priest, R.G., presented at NATO Advanced Science Institute on Polydiacetylenes, Stratford on Avon, U.K., August, 1984
8. Patch clamping of bacteriorhodopsin and its reconstitution in a polymerizable lecithin, Yager, P., Biophysical Journal, 47, no. 2, 93a (1985), presented at Biophysical Society Meeting, Baltimore, February, 1985
9. The effects of pressure on the fusion of lipid vesicles, Chang, E.L., and Yager, P., Biophysical Journal, 47, no. 2, 108a (1985), presented at Biophysical Society Meeting, Baltimore, February, 1985
10. The structure of polymerized lipid tubules, Schoen, P.E., Yager, P., Singh, A., Davies, C., Price, R., and Schnur, J.M., presented at CRDC Conference on Obscuration and Aerosol Research, Aberdeen, June, 1985
11. The structure of tubules formed from a polymerizable lipid, Yager, P., and Schoen, P.E., invited talk at Gordon Conference on Macromolecular and Micellar Catalysis, Brewster Academy, July, 1985
12. The structure of tubules formed from a polymerizable lipid, Yager, P., and Schoen, P.E., invited talk at National Bureau of Standards, Gaithersburg, November, 1985
13. Protein reconstitution in polymerized substrates, Yager, P., invited talk at conference entitled "New Applications of Phospholipid Bilayers, Thin Films and Vesicles", Tenerife, Spain, January, 1986
14. Two mechanisms for forming novel tubular microstructures from polymerizable lipids, Yager, P., Schoen, P.E., Georger, J., Price, R., and Singh, A., Biophysical Journal, 49, no. 2, 320a (1986), presented at Biophysical Society Meeting, San Francisco, February, 1986
15. Reconstitution of acetylcholine receptor from Torpedo californica in polymerizable lipids, Dalziel, A.W., Price, R., Singh, A., and Yager, P., Biophysical Journal, 49, no. 2, 362a (1986), presented at Biophysical Society Meeting, San Francisco, February, 1986
16. Structure determination for drugs and drug/lipid complexes, Rhodes, D.G., Yager, P., Schoen, P.E., and Herbette, L.G., presented at American Crystallographic Association Meeting, June 1986
17. Reconstitution of acetylcholine receptor from Torpedo californica in polymerizable lipids, Dalziel, A.W., Georger, J., Price, R., Singh, A., and Yager, P., presented at Membrane Protein Symposium, San Diego, 1986
18. Orientation of lipid tubules by a magnetic field, Rosenblatt, C., Yager, P., and Schoen, P.E., Biophys. J., 51:185a (1987) presented at Biophysical Society Meeting, New Orleans, February, 1987
19. Phase behavior of a homologous series of polymerizable phospholipids: effect of diacetylene group position on tubule formation, Burke, T.G., Rudolph, A.S., Singh, B.P., Sheridan, J.P., Singh, A., Yager, P., and Schoen, P.E., Biophys. J., 51:185a (1987) presented at Biophysical Society Meeting, New Orleans, February, 1987
20. Structure of polymerized diacetylenic lipid bilayers, Rhodes, D.G., Blechner, S., Schoen, P.E., and Yager, P., Biophys. J., 51:527a (1987) presented at Biophysical Society Meeting, New Orleans, February, 1987
21. Acetylcholine receptor in planar polymerized bilayers--toward a receptor-based biosensor, Yager, P., Dalziel, A.W., Georger, J., Price, R.R., and Singh, A., Biophys. J., 51:143a (1987) presented at Biophysical Society Meeting, New Orleans, February, 1987
22. Measurement of alamethicin-mediated ion translocation through asymmetric polymerized lipid bilayers, Yager, P. and Seib, K., Biophys. J., 53:9a (1988) presented at Biophysical Society Meeting, Phoenix, February 1988
23. Application of patch clamp techniques for the development of membrane-based biosensors, Person, J.J. and Yager, P., 63rd Colloid and Surface Science Symposium, Seattle, June 1989
24. An optical method for detecting the depth of Anesthesia, Merlo, S., Burgess, L.W. and Yager, P., 63rd Colloid and Surface Science Symposium, Seattle, June 1989
25. Spectroscopic analysis and microscopic examination of tubule-forming lipid membranes, Archibald, D.D. and Yager, P., 63rd Colloid and Surface Science Symposium, Seattle, June 1989
26. An optical method for detecting the depth of anesthesia, Merlo, S., Burgess, L.W., and Yager, P., presented at Transducers '89 (5th International Conference of Solid-State Sensors and Actuators & Eurosensors III), Montreux, Switzerland, June 1989
27. Development of a fiber optic sensor for general anesthetics and other small organic molecules, Yager, P., et al., invited talk at Gordon Research Conference on Bioanalytical Sensors, Ventura, CA, March 1990
28. Development of a fiber optic biosensor for measurement of general anesthetics, Yager, P., et al., invited talk at Workshop on Advanced Methods of Pharmacokinetic and Pharmacodynamic Systems Analysis, Marina del Rey, CA, May 1990
29. The use of polymeric lipids in receptor-based biosensors, Yager, P. et al., invited talk (and session co-chair) at 33rd IUPAC Symposium on Macromolecules, Montreal, July 1990
30. Formation of tubular, helical, and cochleate structures from bilayer-forming lipids, Yager P., et al., invited talk at Membrane Structure and Function: The State of the Art--Proceedings of the Indo-U.S. Workshop, Bangalore and Hyderabad, India, January, 1991
31. Development of biosensors based on biomembranes, Yager P., et al., invited talk at Membrane Structure and Function: The State of the Art--Proceedings of the Indo-U.S. Workshop, Bangalore and Hyderabad, India, January, 1991
32. Phase transition sensing for general anesthetics and other small organic molecules, Yager P., et al., invited talk at Washington Exhibition of Science and Technology 1991, Seattle, WA, April 1991
33. Detection of volatile and soluble general anesthetics using a fluorescence-based fiber optic sensor: Recent progress in chemical sensitivity and noise, invited talk at SPIE Biomedical Optics '92, Los Angeles, January 1992
34. Quantitative formation of helical and rodlike microstructures from biological lipids: brain galactocerebroside (Gal-Cer) and its two major subfractions, Yager, P and Archibald, D.D., presented at Biophysical Society meeting, Houston, February, 1992
35. Use of a visible fluorescence dye in a fiberoptic sensor to detect general anesthetics, Susan B. Abrams and Paul Yager, invited talk at SPIE Biomedical Optics '92, Los Angeles, January 1993
36. Raman spectroscopic analysis of the secondary structure of spider silk fiber, invited talk at Army/Air Force Silk Symposium, Charlottesville, VA, January 1993
37. Raman spectroscopy of spider silk: A structural biomaterial? invited talk for Chevron Lecture Series, Department of Chemical Engineering, University of Washington, May 1993
38. Fiber optic sensor for general anesthetics based on Raman spectroscopy, Hillary L. MacDonald and Paul Yager, invited talk at SPIE Biomedical Optics '94, Los Angeles, January 1994
39. Freely suspended solvent-free phospholipid bilayers formed by Langmuir-Blodgett transfer to micromachined apertures in silicon. Osborn, T.D. and Yager, P., presented at Biophysical Society meeting, New Orleans, March, 1994
40. Self-organization of fibroin in silk fibers, Trabbic, K.A., Thiel, B.L., Gillespie, D.B., Viney, C and Yager, P., presented at Biophysical Society meeting, New Orleans, March, 1994
41. A novel drug delivery system based on degradation of tubule lipid microstructures, Carlson, P.A., and Gelb, M.H., and Yager, P., oral presentation at Materials Research Society meeting, Boston, December, 1995
42. Zero-order kinetics of hydrolysis of diacetylenic lipid tubules by phospholipase A2; the influence of microstructure on an interfacial enzyme, Yager, P, Carlson, P.A., and Gelb, M.H., Biophys. J., 70:249A (1996), oral presentation at Biophysical Society meeting, Baltimore, February, 1996
43. Silicon-microfabricated diffusion-based optical chemical sensor, Sensors & Actuators B - Chemical (Conference Proceedings Europtrode III) (1996), Weigl, B.H. and Yager, P.
44. Patterned Sol-Gel Structures by Micro Molding in Capillaries, Lochhead, M.J., Yager, P.Y. Abstract 1996 Materials Research Society Fall Meeting.
45. Fluorescence analyte sensing in whole blood based on diffusion separation in silicon-microfabricated flow structures, Weigl, B.H., Hixon, G. T., Yager, P., SPIE Biomedical Optics, San Jose, Fluorescence Sensing Technology III, 1997, submitted.
46. Diffusion-Based Optical Chemical Detection in Silicon Flow Structures, Weigl, B. H. , Holl, M. A., Schutte, D., Brody, J. P., and Yager, P., µTAS 96, Conference Proceedings, accepted.
47. Rapid Sequential Chemical Analysis Using Multiple Fluorescent Reporter Beads, Weigl, B. H. , van den Engh, G. , Kaiser, R., Altendorf, E., and Yager, P., µTAS 96, Conference Proceedings.
48. Micromachining and Microfabrication, Yager, P., 1997 Gordon Research Conference on Bio/Analytical Sensors, 7/27/97-8/1/97, New England College, New Hampshire, invited
49. Microfluidic Chemical Analytical Systems, Yager, P., NIST Chemistry Division Guest Speaker, 1/98, Gaithersburg, MD, invited
50. Design of Microfluidic Sample Preconditioning Systems for Detection of Biological Agents in Environmental Samples, Yager., P. SPIE Micromachining and Microfabrication Symposium, 9/98, Santa Clara, CA, invited
51. Applying Microfluidic Chemical Analytical Systems to Imperfect Samples, Yager, P., µTAS'98, 10/13/98 to 10/16/98, Banff Park Hotel, Alberta, Canada, invited
52. Microfluidic Chemical Analytical Systems, Yager, P., CPAC Applied Science Meeting, 11/2/99, Meany Tower Hotel, invited
53. Microfluidic Chemical Analytical Systems, Yager, P., U.W. Materials Sciences and Engineering Department Seminar, 2/8/99, invited
54. Microfluidic Chemical Analytical Systems, Yager, P., Higuchi Chemical Sciences Center, University of Kansas, 2/22/99, invited
55. Lipid High Axial Ratio Microstructures for Delivery of Therapeutics, Yager, P., UW Nanotechnology Seminar, 3/30/99, invited
56. Microfluidic Chemical Analytical Systems, Yager, P., Zeneca Conference on Microfluidic Applications to Drug Discovery, London, UK, 6/23/99, invited
57. Microfluidic Chemical Analytical Systems, Yager, P., NIH NIGMS Conference on new approaches to metabolism, Bethesda, MD, 9/13/99, invited
58. Host WTC MEMS Workshop, Aljoya/Battelle Conference Center, Seattle, WA 9/15/99, invited.
59. Recent progress in Microfluidic Chemical Analytical Systems, Yager., P. SPIE Micromachining and Microfabrication Symposium, 9/21/99, Santa Clara, CA, invited
60. Recent progress in Microfluidic Chemical Analytical Systems, Yager, P., DARPA combined Composite CAD/MicroFlumes Planning Meeting, Chantilly, VA, 9/27/99, invited
61. Recent progress in Microfluidic Chemical Analytical Systems, Yager, P., Puget Sound Biotechnology Society Forum, Bothell, WA 10/1/99, invited keynote speaker
62. Recent progress in Microfluidic Chemical Analytical Systems, Yager, P., University of Alberta Department of Chemistry, 10/4/99, invited
63. Recent progress in Microfluidic Chemical Analytical Systems, Yager, P., ARBF Annual National Meeting, Belleview, WA, 2/22/00, invited
64. Recent progress in Microfluidic Chemical Analytical Systems, and Complex High Axial Ratio Microstructures for Drug Delivery, Yager, P., Abbott Research Laboratories, Abbott Park, Illinois, 3/17/00, invited
65. Recent progress in Microfluidic Chemical Analytical Systems, Yager, P., Analytica 2000, 4/13/00, Munich, Germany, invited
66. Analytical devices based on transverse transport in microchannels, Yager, P., Cabrera, C., Hatch, A., Hawkins, K., Holl, M., Kamholz, A., Macounova, K., and Weigl, B.H., µTAS 2000, 5/20/00, University of Twente, Enschede, the Netherlands, platform talk
67. Analytical devices based on transverse transport in microchannels, Yager, P., Cabrera, C., Hatch, A., Hawkins, K., Holl, M., Kamholz, A., Macounova, K., and Weigl, B.H.,Gordon Conference on Separation and Purification, 8/10/00, Colby Sawyer College, NH, invited
68. Analytical devices based on transverse transport in microchannels, Yager, P., et al. Texas A&M Department of Chemistry, 3/1/01, College Park, TX, invited
69. Microfluidic Physics Session Chair and introductory remarks, Yager. P., Gordon Conference on the Physics and Chemistry of Microfluidics, 7/28/01, Oxford, UK, invited.
70. Microfluidics—The interface between biomaterials and MEMS, Yager,
P., UWEB Symposium, 8/20/01, University of Washington, Seattle, WA, invited
71. Analytical devices based on transverse transport in microchannels, Yager
P., et al., CHI BioMEMS and Nanotechnology conference, 9/24/01, Columbus OH,
invited and session chair (cancelled)
72. Recent developments in microfluidic devices for chemical and biochemical
analysis, Yager P. et al., Chemical Engineering Seminar Series, UW, 10/15/01,
invited
73. Cell lysis, protein extraction and enzymatic assay detection in a microfluidic
device, Schilling, E., Kamholz, A.E., and Yager, P., µTAS 2001, 10/23/01,
Monterey, CA, platform talk.
74. The next steps in the evolution of microfluidics: A common format and robust
systems for molecular assembly, Yager, P., DARPA special workshop on Novel Applications
of Microfluidics12/13/01, Dulles, VA, invited talk
75. Microfluidic laminate devices for point-of-care diagnostics, Yager, P. et
al., 1/31/02, UW Department of Oral Biology, Seattle, WA, invited talk
76. Microfluidic laminate devices for point-of-care diagnostics, Yager, P.,
3/25/02, Nanyang Technological University, Singapore, invited seminar
77. Polymeric laminate technology for a rapid diffusion immunoassay, Yager,
P. et al., 4/2/02, Materials Research Society Meeting, San Francisco, CA, invited
talk
78. A microfluidic sample preconditioning system for chem-bio warfare agent
detection and quantification, Yager, P. et al., 4/10/02, BioDefense Mobilization
Conference, Seattle, invited talk
79. Diffusion immunoassay (DIA) for protein analytes, Yager, P. and Hawkins,
K. et al., 5/4/02, IEEE MMB2002 Meeting, Madison, WI, poster and flash presentation
80. Diffusion immunoassay (DIA) for protein analytes, Yager, P. et al., 4/8/02,
Microscale Life Sciences Program seminar, Seattle, invited talk
81. Diffusion immunoassay (DIA) for protein analytes, Yager, P. et al., 6/24/02,
Diagnostic Technologies Panel at BECON Meeting, NIH, Bethesda, MD, invited talk
and panel session
82. The diffusion immunoassay: a rapid assay in microfluidic and static multi-well
formats, Yager, P. et al., 7/29/02, SmallTalk 2002, San Diego, CA, invited talk
83. Microfluidics for low cost medical diagnostics, Yager, P. et al., 9/10/02,
Puget Sound AIChE chapter monthly meeting dinner speaker, invited
84. Microfluidic laminate devices for point-of-care diagnostics, Yager, P. et
al., 9/17/02, Sandia National Laboratories, Albuquerque, NM, invited
85. Microfluidics for low cost medical diagnostics, Yager, P. et al., 9/18/02,
UW Nanotechnology Center’s Nanotechnology Forum, Seattle, invited
86. Microfluidics for low cost medical diagnostics, Yager, P. et al., 10/18/02,
Rosetta Inpharmatics, Bothell, WA, invited
87. Microfluidics for low cost medical diagnostics, Yager, P. et al., 11/18/02,
UC Irvine Departments of Physiology and Bioengineering, invited
88. Biomaterials questions for low cost microfluidic medical diagnostics Yager,
P. et al., 12/19/02, UWEB Meeting in honor of Allan Hoffman’s 70th birthday,
Maui, HA, invited
89. Microfluidics and Engineering a New Doctor-Patient Interface, Yager, P.,
et al., 3/13/03, at Interface between Engineering and Biology and its Impact
on the Human Condition, Regional National Academy of Engineering Meeting, Seattle,
WA, invited
90. Microfluidics for low cost medical diagnostics, Yager, P. et al., 05/15/03,
CHI Mainstreaming Microfluidics Conference, Boston, MA, invited
91. Microfluidics for low cost medical diagnostics, Yager, P. et al., 08/19/03,
Hewlett Packard, Corvallis, OR, invited
92. Microfluidics for low cost medical diagnostics, Yager, P. et al., 08/27/03,
Gordon Research Conference, Physics and Chemistry of Microfluidics, Big Sky,
MT, invited
93. Microfluidics for low cost medical diagnostics, Yager, P. et al., 10/2/03,
BMES Meeting, Nashville, TN, invited (and session chair)
94. Microfluidics for low cost medical diagnostics, Yager, P. et al., 10/16/03,
School of Dentistry, UW, invited
95. Involvement of University faculty with startup companies, Yager, P., 10/22/03,
SSTI Conference, Seattle, WA, invited
96. Microfluidics for low cost medical diagnostics, Yager, P. et al., 10/29/03,
Samsung Advanced Institute of Technology, Korea, invited
97. Microfluidics for low cost medical diagnostics, Yager, P. et al., 10/30/03,
Joint Korea-Japan Symposium, Korea Advanced Institute of Science and Technology,
Korea, invited
98. Microfluidics for low cost medical diagnostics, Yager, P. et al., 10/30/03,
Nanobiotechnology Symposium, Hanyang University, Ansan, Korea, invited
99. Microfluidics and nanotechnology for low cost medical diagnostics, Yager,
P. et al., 3/04/04, NCI Nanotechnology Symposium, FHCRC, Seattle, WA, invited
100. Microfluidic technology for point-of-care diagnostic systems, Yager, P.
et al., 7/15/04, Pacific Northwest Biotechnology Symposium, Seattle, WA, invited
101. Microfluidic technology for point-of-care diagnostic systems, Yager, P.
et al., 7/23/04, Hewlett Packard, Corvallis, OR, invited
102. Microfluidics for point-of-care diagnostics, Yager, P., et al., 9/9/04,
IBEC 2004 Conference, Singapore, invited
103. Microfluidics for point-of-care diagnostics, Yager, P., et al., 9/10/04,
Hewlett Packard Corporation, Singapore, invited
104. Chair session on Microfluidic Diagnostics, 9/30/04, µTAS 2004, Malmö,
Sweden, invited
105. Microfluidics for point-of-care diagnostics, Yager, P., et al., 10/11/04,
UW Department of Oral Biology, invited
106. Microfluidics for point-of-care diagnostics, Yager, P., et al., 10/21/04,
UW Department of Biochemistry, Seattle, WA, invited
107. Microfluidics for point-of-care diagnostics, Yager, P., et al., 10/25/04,
UW Department of Oral Biology, Seattle, WA, invited
108. Microfluidics for point-of-care diagnostics, Yager, P., et al., 11/8/04,
AIChE Annual Meeting, Austin, TX, invited
109. Microfluidics for point-of-care diagnostics, Yager, P., et al., 11/23/04,
Biochemistry Departmental Seminar, UW, Seattle, WA, invited
110. Saliva-based immunoassays for monitoring health status, Yager, P., et al.,
2/7/05, Gordon Conference on Salivary Glands and Exocrine Secretions, Ventura,
CA, invited
111. Development of microfluidic-based point-of-care diagnostic systems, Yager,
P., et al., 07/27/05, Regional Nanotechnology Conference, Portland State University,
Portland, OR, invited
112. Session chair on Crossover Techniques, Yager, P., 8/24/05, Gordon Conference
on Physical and Chemistry of Microfluidics, Oxford, UK, invited
113. Development of microfluidic-based point-of-care diagnostic systems, Yager,
P., et al., 9/29/05, BMES Annual Meeting, Baltimore, MD, invited, and session
chair
114. Microfluidic systems for rapid point-of-care immunoassays, Yager, P., et
al., 10/15/05, AABB Annual Meeting, Seattle, WA, invited
115. Microfluidics for point-of-care diagnostics, Yager, P., et al., 11/03/05,
Student-initiated speaker series, Microfluidics interest group, University of
Michigan, Ann Arbor, ME, invited
116. Personalized Medicine and Microfluidics, Yager, P., 11/16/05, Seattle Bio-Tech
Alliance Personalized Medicine Symposium, Seattle, WA, invited
117. Microfluidics and Global Health Issues, 2/16/06, Indus Partners Symposium
on Global Health, Bellevue, WA, invited
118. Microfluidic POC diagnostics – macro- and micro-views, Yager, P.,
et al., 2/22/06, CHI Tri-Conference, San Francisco, CA, invited
119. Development of microfluidic-based SPR imaging immunoassays, 3/15/06, Yager,
P., et al., PITTCON meeting, Orlando, FA, invited
120. Point of Care Diagnostics for the developed and the developing worlds,
4/3/06, Yager, P., et al., Transdisciplinary Conference on Distributed Diagnosis
and Home Healthcare (D2H2), Washington, DC, invited
(talks not updated beyond 4/06)
National Science Foundation, Division of Chemical, Biochemical, and Thermal Engineering, CBT-8717990, "Morphological Properties of Dispersions of Tubule-Forming Phospholipids"; 8/87 - 9/88; $30,000.
Graduate School Research Fund, "Measurement of Alamethicin Activity in Asymmetric Polymerizable Bilayers; 1/88 - 12/88; $8,193.
Graduate School Research Fund Project Support, "Ion Translocation in Asymmetric Polymerizable Bilayers"; 1/89 - 12/90; $6,341.
National Science Foundation, Division of Chemical, Biochemical, and Thermal Engineering, CTS-8815027, "Structure and Formation of Lipid Tubules"; 20%; 1/89 - 6/92 (3 years plus 6 month no cost extension); $210,262 direct total.
Graduate School Research Fund Equipment Support, "NIH Small Instrumentation Award #5 (to purchase a Perkin-Elmer LS-5B Luminescence Spectrometer; 4/89; $18,310
Washington Technology Center; WTC 09-1044 (first award with this budget number), "Microbiosensor Research"; 7/89 - 6/91; $90,302.
Johnson & Johnson Corporation, "Development of a Portable Fiber Optic Anesthetic Monitoring System"; 11/89 - 2/90; $10,000.
National Science Foundation, IID, BBS SGER Program, "Toward a practical assay for ion channel activity: Can a silicon device support planar lipid bilayers?"; 10/90 - 9/91 plus 6 month extension ; $40,323 total direct .
Graduate School Research Fund BRSG Project Support, "Recognition of Subvocalization EEG by Neural Networks"; 2/91 - 1291; $7,910
Johnson and Johnson Corporation, Corporate Office of Science and Technology, "Possible improvement of biocompatibility of biomaterials by immobilizing phospholipids on their surfaces" (gift to Prof. Allan S. Hoffman and myself); 8/91 - 7/92 (one year); $33,000 direct.
Washington Technology Centers, WTC #09-1044, "Microbiosensor Research"; 15%; 7/91 - 6/93 (two years); $73,000 direct total.
Washington Technology Centers, with Robert Kaiser as Co-PI, WTC #63-1726, "Microfabricated devices for Clinical Chemistry"; 15%; 7/93 - 6/95 (two years); $41,500 direct total
With Prof. Christopher Viney at UW as PI, Yager as Co-PI., National Science Foundation Materials Synthesis and Processing Initiative, "Spinning natural and genetically engineered silk: Advancing liquid crystalline polymer technology" ; 7/92 - 6/95 (three years with additional extension to present); $304,898 total direct, most of which ultimately went to the Yager laboratory.
National Science Foundation BES-9309041 "Raman-Based Fiber Optic Sensor for Anesthetics", 7/93-6/96, $160,502 direct in three years.
University of Washington Royalty Research Fund "Self-Organization of Lipopeptides: Potential Antifungal, Antibacterial and Antitumor Agents", 3/94 - 2/95, $20,000 direct.
DARPA/U.S. Army - Grant #: DAMD17-94-J-4460, Yager as PI, "Development of a Miniaturized Clinical Chemistry Monitor", 20%, 9/94-9/96 , $800,000 Total direct
Senmed Medical Ventures/Micronics, Inc. - 63-2530 UW budget, Yager as PI, Silicon Microfabrication of Optical Devices for Biomedical Assays, 15%, 7/94 - present (open ended) ~$1,570,835 total to date
The Whitaker Foundation "Self-Assembled Prodrug Tubules for Continuous Release", with Mike Gelb of Chemistry as Co-PI, 7/95-6/99, $997,959 total, divided 50/50 with Gelb
Defense Advanced Research Projects Agency, "A Micro-Fluidic Sample Preconditioning System for CBW Agent Detection and Quantification", 5/97-7/00, $ 1,604K total, shared with Co-PI Fred Forster
College of Engineering, "Center for Applied Microtechnologies", 7/97- 5/00 , ~$75K/year total, shared with R.B. Darling, Co-PI
Washington Technology Center, Evaluation of Microfluidic Mixing Strategies for Point-of-Care Diagnostics, WTC RTP project, 1/00-12/01, $72K total
Micronics, Inc., Evaluation of Microfluidic Mixing Strategies for Point-of-Care Diagnostics, WTC RTP project, 1/00-12/01, $24K total
Mesosystems, Inc., "Development of isoelectric focusing for detection of CBW agent" Phase I SBIR subcontract, 4/00 to 8/00, $30K total.
Abbott Laboratories, Hospital Products Division, "Development of tubule-based drug delivery", 6 months, 7/1/00 - 9/30/00, $24K total
NIH NCRR, "Development of Microfluidic Diffusion Immunoassay (DIA)", 4 years, $1M total, 5/01- 4/05
Mesosystems, Inc., "Development of isoelectric focusing for detection of CBW agent" Phase II Fast Track SBIR subcontract, 4/01-3/03, ~$128K total
Singapore National Science and Technology Board, Singapore UW Alliance, 5
years, 5/02 – 4/07, amount confidential
MesoSystems, Inc., "Development of isoelectric focusing extraction and
concentration of DNA" Phase II SBIR subcontract, 10/02-09/03, ~$65K total
NIH NIDCR, “Rapid parallel salivary immunoassays on a disposable”,
4 years, 9/02 – 8/06, $3.8M total
NIH NIBIB, “Microfluidic Technology for Gene Delivery Systems” (Kenneth Longmuir, UC Irvine, PI), 9/15/03-09/14/08, $433K total
Hewlett Packard Corporation, “Printing Functional Proteins”, 9 months, 12/03 – 8/04, $75K total
NIH NIAID, “1 U01 AI61187-01 -- A multiplex, point-of-care test for enteric pathogens” (Bernhard Weigl, PATH, PI), 9/04 – 8/08, ~$465K total to PY lab
NASA, Development of a DNA-Based Detector Array for Microbial Monitoring of the ISS Water System (David Stahl, PI), 1/05 – 12/07, $486K total to PY labThe Bill and Melinda Gates Foundation, Grand Challenges in Global Health, “A Point-of-Care Diagnostic System for the Developing World”, 5 years, $15.4M total, 7/05 –6/10
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