Publications:

• Mulder AM, Glavis-Bloom A, Moores CA, Wagenbach M, Carragher B, Wordeman L, Milligan RA. A new model for binding of kinesin 13 to curved microtubule protofilaments. J Cell Biol. 2009 Apr 6;185(1):51-7.

• Powers AF, Franck AD, Gestaut DR, Cooper J, Gracyzk B, Wei RR, Wordeman L, Davis TN, Asbury CL. The Ndc80 kinetochore complex forms load-bearing attachments to dynamic microtubule tips via biased diffusion. Cell 2009 136:865-875.

• Wagenbach M, Domnitz S, Wordeman L, Cooper J. A kinesin-13 mutant catalytically depolymerizes microtubules in ADP. J Cell Biol. 2008 Nov 17;183(4):617-23.

• Gestaut DR, Graczyk B, Cooper J, Widlund PO, Zelter A, Wordeman L, Asbury CL, Davis TN. Phosphoregulation and depolymerization-driven movement of the Dam1 complex do not require ring formation. Nat Cell Biol. 2008 Apr;10(4):407-14.

• Stumpff J, von Dassow G, Wagenbach M, Asbury C, Wordeman L. The kinesin-8 motor Kif18A suppresses kinetochore movements to control mitotic chromosome alignment. Dev Cell. 2008 Feb;14(2):252-62.

• Wordeman L, Wagenbach M, von Dassow G.MCAK facilitates chromosome movement by promoting kinetochore microtubule turnover. J Cell Biol. 2007 Dec 3;179(5):869-79.

• Peris L, Thery M, Faure J, Saoudi Y, Lafanechere L, Chilton JK, Gordon-Weeks P, Galjart N, Bornens M, Wordeman L, Wehland J, Andrieux A, Job D. Tubulin tyrosination is a major factor affecting the recruitment of CAP-Gly proteins at microtubule plus ends. J Cell Biol. 2006 174(6):839-49.

• Moores CA, Cooper J, Wagenbach M, Ovechkina Y, Wordeman L, Milligan RA. The role of the kinesin-13 neck in microtubule depolymerization. Cell Cycle. 2006 5(16):1812-5.

• Parra MT, Gomez R, Viera A, Page J, Calvente A, Wordeman L, Rufas JS, Suja JA. A Perikinetochoric Ring Defined by MCAK and Aurora-B as a Novel Centromere Domain. PLoS Genet. 2006 2(6):e84

• Brown CL, Maier KC, Stauber T, Ginkel LM, Wordeman L, Vernos I, Schroer TA. Kinesin-2 is a motor for late endosomes and lysosomes. Traffic. 2005 6:1114-24.

• Moore, AT, Rankin, KE, von Dassow, G, Peris, L., Wagenbach, M., Ovechkina, Y., Andrieux, A., Job, D., and L. Wordeman. MCAK associates with the tips of polymerizing microtubules. 2005. J. Cell Biol. 169:391-397.

• Lawrence CJ, Dawe RK, Christie KR, Cleveland DW, Dawson SC, Endow SA, Goldstein LS, Goodson HV, Hirokawa N, Howard J, Malmberg RL, McIntosh JR, Miki H, Mitchison TJ, Okada Y, Reddy AS, Saxton WM, Schliwa M, Scholey JM, Vale RD, Walczak CE, Wordeman L. 2004. A standardized kinesin nomenclature. J Cell Biol. 167(1):19-22.
  

• Moore A, Wordeman L.2004. C-terminus of mitotic centromere-associated kinesin (MCAK) inhibits its lattice-stimulated ATPase activity. Biochem J. 383(Pt 2):227-35.

• Newton CN, Wagenbach M, Ovechkina Y, Wordeman L, Wilson L. 2004. MCAK, a Kin I kinesin, increases the catastrophe frequency of steady-state HeLa cell microtubules in an ATP-dependent manner in vitro. FEBS Lett. 13;572(1-3):80-4.

• Andrews PD, Ovechkina Y, Morrice N, Wagenbach M, Duncan K, Wordeman L, Swedlow JR. 2004 . Aurora B regulates MCAK at the mitotic centromere. Dev Cell. 6(2):253-68.

• Hunter AW, Caplow M, Coy DL, Hancock WO, Diez S, Wordeman L, Howard J. 2003. The kinesin-related protein MCAK is a microtubule depolymerase that forms an ATP-hydrolyzing complex at microtubule ends. Mol. Cell 11:445-457.

• Ovechkina Y, Wagenbach M, Wordeman L. 2002. K-loop insertion restores microtubule depolymerizing activity of a "neckless" MCAK mutant. J. Cell Biol. 159:557-62

• Maney T, Wagenbach M, Wordeman L. 2001. Molecular dissection of the microtubule depolymerizing activity of mitotic centromere-associated kinesin. J Biol Chem. 276:34753-8.

• Ginkel, L. and L. Wordeman. 2000. Expression and partial characterization of kinesin-related proteins in differentiating and adult skeletal muscle. Mol Biol Cell. 12:4143-58..

• Wordeman, L., M. Wagenbach, and T. Maney. 1999. Mutations in the ATP-Binding domain affect the Subcellular Distribution of Mitotic Centromere-associated Kinesin (MCAK). Cell Biol. Int. 23:275-286.

• Maney, T., A. W. Hunter, M. Wagenbach, and L. Wordeman. 1998. Mitotic centromere-associated kinesin is important for anaphase chromosome segregation. J. Cell Biol. 142:787-801.

• Faulkner, N.E., B. Vig, C. Echeverri, L. Wordeman, and R.B. Vallee. 1998. Localization of motor-related proteins and associated complexes to primary but not secondary centromeres. Hum. Mol. Genet. 7:671-677.

• Wordeman, L., W.C. Earnsharw, and R.L. Bernat. 1996. Disruption of CENP antigen function perturbs dynein anchoring to the mitotic kinetochore. Chromosoma 104:551-60.

• Wordeman, L., and T. J. Mitchison. 1995. Identification and preliminary characterization of MCAK, a kinesin-related protein that associates with centromeres during mitosis. J. Cell Biol. 128:95-106.

• Sawin, K.E., T.J. Mitchison, and L.G. Wordeman. 1992. Evidence for kinesin-related proteins in the mitotic apparatus using peptide antibodies. J. Cell Sci. 101:303-313.

• Wordeman, L., E.R. Steuer, M.P. Sheetz, and T. Mitchison. 1991. Chemical subdomains within the kinetochore domain of isolated CHO mitotic chromosomes. J. Cell Biol. 114:285-294.

• Steuer, E.R., L. Wordeman, T.A. Schroer, and M.P. Sheetz. 1990. Localization of cytoplasmic dynein to mitotic spindles and kinetochores. Nature 345:266-268. 

Reviews:

• Cooper, J.R. and L. Wordeman. 2009. The diffusive interaction of microtubule binding proteins. Curr. Opin. Cell Biol. 21:68-73.
• Davis, T.N. and L. Wordeman. 2007. Rings, bracelets, sleeves and chevrons: new structures of kinetochore proteins. Trends Cell Biol. 17:377-382.

• Stumpff, J. and L. Wordeman. 2007. Chromosome congression: the kinesin-8-step path to alignment. Curr. Biol. 17:R326-328.

• Wordeman, L. 2005. Microtubule-depolymerizing Kinesins. Curr. Opin. Cell Biol. 17:82-88.

• Moore A, Wordeman L. 2004. The mechanism, function and regulation of depolymerizing kinesins during mitosis.Trends Cell Biol. 14(10):537-46.

• Wordeman L. Breathing down the neck of Unc104. 2003. J Cell Biol. 163(4):693-5.

• Ovechkina Y. and Wordeman L. 2003. Unconventional motoring: an overview of the kin C and kin I kinesins. Traffic 4:367-75.

• Ginkel, L. and L. Wordeman. 2001. Expression cloning with pan kinesin antibodies. In: Methods Mol Biol. 164:21-41.

• Hunter, A.W. and L. Wordeman. 2000. How motor proteins influence microtubule dynamics. J. Cell Sci. 113:4379-4389.

• Maney, T., L. Ginkel, A.W. Hunter and L. Wordeman. 2000. The kinetochore of higher eukaryotes: A molecular view. In: Int. Review of Cytology: A survey of cell biology. Vol. 194. K. W. Jeon (Ed.). Academic Press, San Diego, CA, USA. pp. 67-131.

• Wordeman, L., and M. Wagenbach. 1999. Using Antisense Technology to Study Mitosis. In Meth. Cell Biol. Vol. 61. C. Rieder (Ed). Academic Press, San Diego, CA, USA. pp. 245-266.

• Wordeman, L. 1995. Mechanisms of chromosome segregation in metazoan cells. In Prog Cell Cycle Res. Vol I. L. Meijer, S. Guidet and H.Y. Tung, eds. Plenum Press, New York, USA.. pp. 319-327.

• Wordeman, L., and W.Z. Cande. 1990. Cytokinesis by furrowing in diatoms. In: Cytokinesis: Mechanisms of Furrow Formation During Cell Division. Vol. 582. G. W. Conrad and T. E. Schroeder (Eds). Ann. N.Y. Acad. Sci. pp. 252-259.