LECTURES
    1988
  1. 7 Dec: Annual symposium of Medicinal Chemistry - University of Antwerp, Belgium
    The kappa-opioid pharmacophore in 6,7-benzomorphans

    1989

  2. 30 Nov: Biotechnology course - University of Nijmegen, The Netherlands (Host: Dr. Ruud Konings)
    Molecular modeling: principles and applications

    1990

  3. 12 Jan: BIOS Lecture - University of Groningen, The Netherlands
    Towards new sleeping sickness drugs by structure-based drug design
  4. 13 Jul: Protein Structural Aspects of Biotechnology. COMETT Advanced Course - University of Nijmegen, The Netherlands (invited speaker)
    Protein engineering and drug design
  5. 26 Nov: 2nd Symposium on Biochemical Biotechnology - Villa Olmo, Como, Italy (Invited speaker)
    Ab initio design of selective inhibitors of trypanosomal triosephosphate isomerase: toward new drugs against sleeping sickness

    1991

  6. 15 Apr: Int. Org. for Chemistry in Development Meeting - Institute for Cellular Pathology, Brussels, Belgium (Host: Dr. Fred Opperdoes)
    Rational design of anti-trypanosomal agents
  7. 10 Jun: University Centre for Pharmacy RUG - Groningen, The Netherlands (Host: Dr. Alan Horn)
    The linked-fragment approach as a tool for inhibitor design: towards new drugs against trypanosomiasis

    1992

    None: due to relocation

    1993

  8. 25 Mar: Seattle Protozoology Conference - Seattle, WA
    Successful rational selective inhibition of a trypanosomal enzyme
  9. 27 May: Annual meeting of the American Crystallographic Association - Albuquerque, NM
    Successful rational selective inhibition of a trypanosomal enzyme
  10. 19 Aug: Department of Pharmaceutical Sciences UCSF (Host: Dr. Irwin Kuntz)
    Protein structure-based design for selective inhibition of glyceraldehyde-3-phosphate dehydrogenase: towards new drugs for the treatment of sleeping sickness
  11. 12 Sep: Albany Conference: Molecular Mechanisms of Drug Resistance - Rensselaerville, NY (Invited speaker)
    Drug design in protozoa
  12. 16 Sep: BIOSYM Scientific Seminar Series - Seattle, WA(Invited speaker)
    Successful rational selective inhibition of a trypanosomal enzyme
  13. 22 Nov: BASF - Ludwigshafen, Germany (Host: Dr. Hans-Joachim Boehm)
    Protein structure-based drug design: from an aspecific lead to a 500-fold gain in selectivity

    1994

  14. 25 Feb: Department of Biological Structure Seminar - Seattle , WA
    Protein structure-based inhibitor design for tropical diseases
  15. 11 Apr: The third Pacific Northwest Protein Crystallography Workshop - Seattle
    Protein structure-based inhibitor design: expectations and facts
  16. 27 Jul: 3rd International satellite meeting: on the conformational analysis of carbohydrates & protein/carbohydrate interactions - Val Morin, Canada (Invited speaker)
    Characterization of the carbohydrate receptor site in the cholera toxin family and its exploitation for drug design
  17. 2 Sep: 15th European Crystallographic Meeting - Dresden, Germany (Invited speaker)
    Selective protein structure-based drug design:toward new drugs for the treatment of sleeping sickness

    1995

  18. 20 Jan: Faculty Candidate Seminar - University of Washington, Seattle, WA
    Protein structure-based drug design: fact or fiction?
  19. 9 Feb: Looking at protein structures and nucleic acids - University of Leuven, Belgium (Invited speaker)
    Towards new drugs against trypanosomiasis and cholera: drug design on the basis of protein structures
  20. 24 May: 36th Annual Buffalo Medicinal Chemistry Symposium - Buffalo (Session organizer and speaker)
    Selective inhibition of trypanosomal glyceraldehyde-3-phosphate dehydrogenase by protein structure-based drug design: toward new drugs for the treatment of sleeping sickness
  21. 28 Jul: Annual meeting of the American Crystallographic Association - Montreal (Session organizer and speaker)
    Protein structure-based drug design: progress, results and challenges

    1996

  22. 1 Mar: Medicinal Chemistry Seminar - University of Washington, Seattle (Host: Dr. Valerie Daggett)
    Structure-based drug design: recipes for success
  23. 17 Apr: Biochemistry Dept., Wake Forest University, Winston-Salem, NC (Host: Dr. Al Claiborne)
    Structure-based Drug Design for Tropical Diseases
  24. 19 Apr: 4th Bud Suddath Memorial Symposium - Georgia Institute of Technology, Atlanta (Host: Dr. Jim Powers)
    Structure-based Drug Design for Tropical Diseases
  25. 26 Apr: UAB Structure-based drug design Conference - Panama City Beach (Invited speaker)
    Structure-Based Optimization of Poor Leads: From high millimolar to low micromolar inhibitors

    1997

  26. 28 Jan: UW Computer Science & Engineering (Host: Dr. Richard Karp; televised on UW TV channel)
    Computational and algorithmic challenges in structure-based drug design
  27. 29 Jul: 662nd British Biochemical Society Meeting - Dundee, Scotland (Invited speaker)
    Selective inhibition of glycolysis in tropical parasites by structure-based drug design
  28. 1 Aug: University of York, Department of Chemistry - York,UK (Host: Dr. Koen Verschueren)
    Selective inhibition of glycolysis in tropical parasites by structure-based drug design
  29. 4 Aug: University of Leicester, Department of Biochemistry - Leicester, UK (Host: Dr. Tina Izard)
    Selective inhibition of glycolysis in tropical parasites by structure-based drug design
  30. 11 Sep: American Chemical Society Meeting - Las Vegas (Invited speaker)
    Anchor-based drug design

    1998

  31. 7 Dec: INABIS (Internet Association for BIomedical Sciences) '98: 5th Internet World Congress on Biomedical Sciences (Invited speaker)
    Five Orders of Magnitude Affinity Gain in Anti-trypanosomal Drug Development
    available from URL: http://www.mcmaster.ca/inabis98/pharmtox/verlinde0900/index.html

    1999

  32. 25 Jan: University of British Columbia, Department of Biochemistry and Molecular Biology - Vancouver, Canada (Host: Dr. Michael Murphy)
    Five Orders of Magnitude Affinity Gain in Anti-trypanosomal Drug Development by Structure-based Design
  33. 23 Mar: DowAgrochemicals, Indianapolis, IN (Host: Dr. Terry Walsh)
    Five Orders Affinity Gain by Selective Structure-based Design
  34. 25 May: Annual meeting of the American Crystallographic Association - Buffalo
    Five Orders of Magnitude Affinity Gain in Anti-trypanosomal Drug Development by Structure-based Design
  35. 3 Jun: General Meeting of the American Society of Microbiology - Chicago (Invited speaker)
    Structure-based Drug Design
  36. 21 Oct: Christan de Duve Institute of Cellular Pathology - Universite Catholique de Louvain - Belgium (Host: Dr. Paul Michels)
    Structure-based strategies for disabling cholera toxin and heat-labile enterotoxin, masters of cellular trafficking
  37. 10 Nov: Eli-Lilly - Indianapolis (Host: Dr. Genshi Zhao)
    Five Orders of Magnitude Affinity Gain in Anti-trypanosomal Drug Development by Structure-based Design

    2000

  38. 19 Apr: UW Biophysics Seminar
    A new and fast molecular docking approach: stochastic approximation with smoothing

    2001

  39. 17 Jan: Nortwestern University - Chicago (Host: Dr. Brian Shoichet)
    A new and fast molecular docking approach: stochastic approximation with smoothing
  40. 20 Jun: "Modeling of protein interactions in genomes", Charleston, SC (Invited speaker)
    A new and fast molecular docking approach: stochastic approximation with smoothing
  41. 23 Jul: Structural GenomiX, San Diego, CA (Host: Dr. Mike Milburn)
    Structure-based design: a case study and a new algorithm
  42. 26 Aug: ACS National Meeting Chicago (Invited speaker)
    A new and fast molecular docking approach: stochastic approximation with smoothing
  43. 11 Nov: 1st Brazilian Symposium on Medicinal Chemistry "New approaches in drug design" Caxambu, Minas Gerais, Brazil (Invited keynote speaker)
    Protein structure-based design of antiprotozoal drugs

    2002-2004

    None, due to long term hospitalization and slow recovery. Healthy now!

    2005

  44. 11-12 Nov: Peruvian University Cayetano Heredia: Amauta 3rd International Course on Biomedical and Health Informatics, Lima, Peru (Invited speaker)
    Protein structure-based design: methods and practice (3 lectures)

    2006

  45. 3 Aug: University of Colorado at Denver / Health Sciences Center at Aurora (Host: Dr. Rui Zhao)
    At War against Malaria: Structural Genomics and Structure-based Drug Design Efforts

    2008

  46. 8-9 May: Peruvian University Cayetano Heredia: Global Health Informatics: Advances in Public Health and Genomics, Lima, Peru (Invited speaker)
    Protein structure-based design: methods and practice (3 lectures)

    2009

  47. 2 Jun: 2nd Conference on drug development for the third world: From computational molecular biology to experimental approaches, Abdus Salam ICTP, Miramare, Trieste, Italy (Invited speaker)
    Protein structure-based design: Forces
  48. 2 Jun: 2nd Conference on drug development for the third world: From computational molecular biology to experimental approaches, Abdus Salam ICTP, Miramare, Trieste, Italy (Invited speaker)
    Protein structure-based design: Energies
  49. 3 Jun: 2nd Conference on drug development for the third world: From computational molecular biology to experimental approaches, Abdus Salam ICTP, Miramare, Trieste, Italy (Invited speaker)
    The TDR drug target database
  50. 3 Jun: 2nd Conference on drug development for the third world: From computational molecular biology to experimental approaches, Abdus Salam ICTP, Miramare, Trieste, Italy (Invited speaker)
    Protein structure-based design: Solvation
  51. 4 Jun: 2nd Conference on drug development for the third world: From computational molecular biology to experimental approaches, Abdus Salam ICTP, Miramare, Trieste, Italy (Invited speaker)
    Protein structure-based design: Scoring functions
  52. 4 Jun: 2nd Conference on drug development for the third world: From computational molecular biology to experimental approaches, Abdus Salam ICTP, Miramare, Trieste, Italy (Invited speaker)
    Protein structure-based design: Docking
  53. 5 Jun: 2nd Conference on drug development for the third world: From computational molecular biology to experimental approaches, Abdus Salam ICTP, Miramare, Trieste, Italy (Invited speaker)
    Protein structure-based design: Absorption, distribution)
  54. 5 Jun: 2nd Conference on drug development for the third world: From computational molecular biology to experimental approaches, Abdus Salam ICTP, Miramare, Trieste, Italy (Invited speaker)
    Protein structure-based design: Metabolism and excretion)
  55. 5 Jun: 2nd Conference on drug development for the third world: From computational molecular biology to experimental approaches, Abdus Salam ICTP, Miramare, Trieste, Italy (Invited speaker)
    Design of new anti-Chagas therapeutics
  56. 31 Aug: University of Montana, Missoula (Host: Dr. David Bolstad)
    Structure-based design of new drugs for Chagas disease by targeting T.cruzi CYP51

    2011

  57. 18 May: Dutch Cancer Institute, Amsterdam, The Netherlands (Host: Dr. Titia Sixma)
    Forging a human prenylation inhibitor into a T. cruzi ergosterol synthesis blocker that cures mice from acute Chagas disease
  58. 19 May: University of Utrecht, The Netherlands (Host: Dr. Piet Gros)
    Forging a human prenylation inhibitor into a T. cruzi ergosterol synthesis blocker that cures mice from acute Chagas disease
  59. 20 Sep: Durham University, Durham, England, UK (Host: Dr. Ehmke Pohl)
    Design of 14-alpha-steroldemethylase inhibitors for Chagas disease.

    2012

  60. 4 Sep: Dutch Academy of Sciences, Amsterdam, The Netherlands
    Methionyl-tRNA synthetase inhibitors for treating late stage African trypanosomiasis
  61. 26 Sep: Durham University, Durham, England, UK (Host: Dr. Ehmke Pohl)
    Design of methionyl-tRNA synthetase inhibitors for treating African trypanosomiasis

    2015

  62. 19 Feb: University of Dundee, Scotland (Host: Dr. Bill Hunter)
    Targeting methionyl-tRNA synthetase of African trypanosomes
  63. 20 Feb: University of Glasgow, Scotland (Host: Dr. Jeremy Mottram)
    Targeting methionyl-tRNA synthetase of African trypanosomes
  64. 26 Feb: Durham University, England (Host: Dr. Ehmke Pohl)
    Targeting methionyl-tRNA synthetase of African trypanosomes
  65. 27 Feb: Newcastle University, England (Host: Dr. Martin Noble)
    Targeting methionyl-tRNA synthetase of African trypanosomes