=============================== MCDS Version 3.00B 15-JUL-2011 =============================== 0.959 running time (min) 1.0000E+00 DNA content (Gbp) 5.0000E+00 Dia. of cell nucleus (um) 10000 number of cells (nocs) 987654321 random number seed PARTICLE: proton (mass = 1.00728E+00 u = 9.38272E+02 MeV/c^2) 1.00000E+03 MeV >= 6.47020E-03 MeV 1.00000E+03 MeV/A >= 6.47020E-03 MeV/A) 1.69604E+03 MeV (p*c = momentum x speed of light) 7.31116E-04 pm (de Broglie wavelength) 2.06579E+00 = T/m0c2+1 (Lorentz factor) >= 1 1.00000E+00 ABS(effective charge); Barkas 1963 8.75026E-01 beta = (v/c) <= 1 1.30605E+00 (zeff/beta)^2 <= 1.000E+04 DOSIMETRY (@ point of entry into cell nucleus) 3.61536E-01 absorbed dose per unit fluence (nGy-cm^2/particle) 3.19552E+02 cm (CSDA range) 2.25710E-01 keV/um (total stopping power) 2.25677E-01 keV/um ( 99.985% electronic) 3.29553E-05 keV/um ( 0.015% nuclear) MICRODOSIMETRY (target = 5.000 um diameter cell nucleus) 3.3333E+00 um (avg. chord length = 4V/S = 2d/3) 7.5216E-01 keV (energy imparted per event) 2.2565E-01 keV/um (frequency-mean lineal energy) 1.8413E-03 Gy (frequency-mean specific energy) 5.4310E+02 1/Gy (event frequency per unit absorbed dose) DAMAGE FORMATION AND CLUSTERING (normoxic conditions) 148598 segment length, nseg (bp per cell per Gy) 1300 number of strand breaks, sigSb (per cell per Gy) 3900 number of base damages, sigBd (per cell per Gy) 3.0 base damage to strand break ratio, f 9 minimum distance between clusters, Nmin (bp) 10 maximum distance between two Sb to compose a DSB, Ndsb (bp) 0.0 fraction Bl/Bd OXYGEN SIMULATION (M0=1.740, K=0.3372, q=946.10, r=2.15) 1.0000E+02 % O2 concentration (=760.00 mmHg) 2.4807E-03 chemical repair probability (pcr) 9.9752E-01 O2 fixation probability (1-pcr) 1.0025E+00 Approx. HRF for SSB induction [=1/(1-pcr)] 1.0050E+00 Approx. HRF for DSB induction [1/(1-pcr)]^2 DMSO SIMULATION 5.0000E-01 fraction of non-scavengeable DNA damage (fnsd) 5.0000E-01 concentration (mol dm^-3) at half-level (chmx) 0.0000E+00 DMSO concentration (mol dm^-3) TABLE 1. Percent (%) cluster yields by complexity, as classified using the scheme of Nikjoo et al. (IJRB 71, 467-483 1997 and and Radiat. Res. 156, 577-583 2001). =================================================================================================================== 68.404 BD - one or more Bd (no Sb) 28.824 SSB - Sb (no auxilary damage) 1.286 SSB+ - two Sb on the same strand 0.160 2SSB - two or more Sb on opposite strands separated by at least 10 bp 1.153 DSB - two Sb on opposite strands with a separation <= 10 bp 0.156 DSB+ - DSB accompanied by one (or more) additional Sb within 10 bp separation 0.018 DSB++ - more than one DSB whether within the 10 bp separation or further apart 4.777 SSBc - fraction of complex damage (SSB+ and 2SSB) among SSBs 40.369 SSBcb - fraction of complex damage (SSB+ and 2SSB) among SSBs; base damage included 13.079 DSBc - fraction of complex damage (DSB+ and DSB++) among DSBs 51.133 DSBcb - fraction of complex damage (DSB+ and DSB++) among DSBs; base damage included =================================================================================================================== TABLE 2. Number of clusters per cell per Gy. Cluster yields are for a representative cell containing an average of 1.000 Gbp (giga basepair) of DNA. Cluster induction is proportional to absorbed dose up to at least a hundred or thousand Gy. The category "OTHER" includes all classes of individual and clustered DNA lesion, except for SSB and DSB. SEM = standard error of the mean. =================================================================================================================== Number of --------- DSB ---------- --------- SSB ---------- -------- OTHER --------- ----- ALL CLUSTERS ----- lesions Average SEM Average SEM Average SEM Average SEM =================================================================================================================== 1 --- --- 1.12634E+02 3.16400E-02 3.37931E+02 5.86061E-02 4.50565E+02 7.04624E-02 2 4.04810E+00 7.95749E-03 5.08309E+01 2.52845E-02 7.04854E+01 2.90795E-02 1.25364E+02 3.78326E-02 3 2.53288E+00 6.31145E-03 1.76328E+01 1.62057E-02 1.46838E+01 1.45362E-02 3.48494E+01 2.14005E-02 4 1.08535E+00 4.22325E-03 5.52543E+00 9.24578E-03 3.06293E+00 6.90188E-03 9.67372E+00 1.20147E-02 5 4.01933E-01 2.57111E-03 1.64502E+00 5.19134E-03 6.36717E-01 3.24045E-03 2.68367E+00 6.53583E-03 6 1.38833E-01 1.50867E-03 4.70767E-01 2.77624E-03 1.32400E-01 1.45679E-03 7.42000E-01 3.42463E-03 7 4.62833E-02 8.79094E-04 1.30417E-01 1.48050E-03 2.72167E-02 6.75873E-04 2.03917E-01 1.84336E-03 8 1.50167E-02 5.03298E-04 3.59333E-02 7.73050E-04 5.63333E-03 3.06689E-04 5.65833E-02 9.68782E-04 9 4.75000E-03 2.79337E-04 1.07667E-02 4.25027E-04 1.31667E-03 1.47558E-04 1.68333E-02 5.30747E-04 10 1.55000E-03 1.59986E-04 2.63333E-03 2.07846E-04 1.66667E-04 5.26809E-05 4.35000E-03 2.65734E-04 11 4.16667E-04 8.32333E-05 7.50000E-04 1.11557E-04 3.33333E-05 2.35690E-05 1.20000E-03 1.40918E-04 12 8.33333E-05 3.72603E-05 1.83333E-04 5.52494E-05 --- --- 2.66667E-04 6.66166E-05 13 3.33333E-05 2.35690E-05 5.00000E-05 2.88646E-05 --- --- 8.33333E-05 3.72603E-05 14 1.66667E-05 1.66667E-05 --- --- --- --- 1.66667E-05 1.66667E-05 15 --- --- --- --- --- --- --- --- 16 --- --- --- --- --- --- --- --- 17 --- --- --- --- --- --- --- --- 18 --- --- --- --- --- --- --- --- 19 --- --- --- --- --- --- --- --- 20 --- --- --- --- --- --- --- --- 21 --- --- --- --- --- --- --- --- 22 --- --- --- --- --- --- --- --- 23 --- --- --- --- --- --- --- --- 24 --- --- --- --- --- --- --- --- 25 --- --- --- --- --- --- --- --- 26 --- --- --- --- --- --- --- --- 27 --- --- --- --- --- --- --- --- 28 --- --- --- --- --- --- --- --- 29 --- --- --- --- --- --- --- --- 30 --- --- --- --- --- --- --- --- 31 --- --- --- --- --- --- --- --- 32 --- --- --- --- --- --- --- --- 33 --- --- --- --- --- --- --- --- 34 --- --- --- --- --- --- --- --- 35 --- --- --- --- --- --- --- --- 36 --- --- --- --- --- --- --- --- 37 --- --- --- --- --- --- --- --- 38 --- --- --- --- --- --- --- --- 39 --- --- --- --- --- --- --- --- 40 --- --- --- --- --- --- --- --- 41 --- --- --- --- --- --- --- --- 42 --- --- --- --- --- --- --- --- 43 --- --- --- --- --- --- --- --- 44 --- --- --- --- --- --- --- --- 45 --- --- --- --- --- --- --- --- 46 --- --- --- --- --- --- --- --- 47 --- --- --- --- --- --- --- --- 48 --- --- --- --- --- --- --- --- 49 --- --- --- --- --- --- --- --- 50 --- --- --- --- --- --- --- --- Total 8.27525E+00 1.08728E-02 1.88920E+02 2.47388E-02 4.26966E+02 4.39335E-02 6.24161E+02 4.58014E-02 ------------------------------------------------------------------------------------------------------------------- TABLE 3. Cluster composition (% Sb per cluster) =================================================================================================================== Number of --------- DSB ---------- --------- SSB ---------- -------- OTHER --------- ----- ALL CLUSTERS ----- lesions Average SEM Average SEM Average SEM Average SEM =================================================================================================================== 1 --- --- 1.66667E+01 0.00000E+00 0.00000E+00 0.00000E+00 4.16638E+00 9.63991E-04 2 1.66667E+01 0.00000E+00 8.95513E+00 1.24890E-03 0.00000E+00 0.00000E+00 4.16909E+00 1.57004E-03 3 1.20262E+01 5.49341E-03 6.51436E+00 2.14788E-03 0.00000E+00 0.00000E+00 4.16983E+00 2.70891E-03 4 9.81716E+00 9.83894E-03 5.36139E+00 3.68352E-03 0.00000E+00 0.00000E+00 4.16239E+00 4.63004E-03 5 8.51619E+00 1.67080E-02 4.71608E+00 6.89352E-03 0.00000E+00 0.00000E+00 4.16743E+00 8.29979E-03 6 7.70345E+00 2.58858E-02 4.28568E+00 1.34040E-02 0.00000E+00 0.00000E+00 4.16853E+00 1.61062E-02 7 7.06599E+00 3.98385E-02 4.00235E+00 2.27112E-02 0.00000E+00 0.00000E+00 4.17998E+00 2.76955E-02 8 6.58831E+00 6.64893E-02 3.81586E+00 3.84233E-02 0.00000E+00 0.00000E+00 4.17682E+00 4.45063E-02 9 6.24264E+00 1.14584E-01 3.55954E+00 6.34542E-02 0.00000E+00 0.00000E+00 4.03790E+00 7.44571E-02 10 6.29032E+00 2.25234E-01 3.55485E+00 1.31409E-01 0.00000E+00 0.00000E+00 4.39336E+00 1.48733E-01 11 5.81818E+00 3.11498E-01 3.50168E+00 2.44701E-01 0.00000E+00 0.00000E+00 4.20875E+00 2.42032E-01 12 6.11111E+00 1.03935E+00 3.15657E+00 4.22556E-01 --- --- 4.07986E+00 5.44873E-01 13 5.12820E+00 0.00000E+00 3.41880E+00 1.13066E+00 --- --- 4.10256E+00 7.47558E-01 14 2.38095E+00 0.00000E+00 --- --- --- --- 2.38095E+00 0.00000E+00 15 --- --- --- --- --- --- --- --- 16 --- --- --- --- --- --- --- --- 17 --- --- --- --- --- --- --- --- 18 --- --- --- --- --- --- --- --- 19 --- --- --- --- --- --- --- --- 20 --- --- --- --- --- --- --- --- 21 --- --- --- --- --- --- --- --- 22 --- --- --- --- --- --- --- --- 23 --- --- --- --- --- --- --- --- 24 --- --- --- --- --- --- --- --- 25 --- --- --- --- --- --- --- --- 26 --- --- --- --- --- --- --- --- 27 --- --- --- --- --- --- --- --- 28 --- --- --- --- --- --- --- --- 29 --- --- --- --- --- --- --- --- 30 --- --- --- --- --- --- --- --- 31 --- --- --- --- --- --- --- --- 32 --- --- --- --- --- --- --- --- 33 --- --- --- --- --- --- --- --- 34 --- --- --- --- --- --- --- --- 35 --- --- --- --- --- --- --- --- 36 --- --- --- --- --- --- --- --- 37 --- --- --- --- --- --- --- --- 38 --- --- --- --- --- --- --- --- 39 --- --- --- --- --- --- --- --- 40 --- --- --- --- --- --- --- --- 41 --- --- --- --- --- --- --- --- 42 --- --- --- --- --- --- --- --- 43 --- --- --- --- --- --- --- --- 44 --- --- --- --- --- --- --- --- 45 --- --- --- --- --- --- --- --- 46 --- --- --- --- --- --- --- --- 47 --- --- --- --- --- --- --- --- 48 --- --- --- --- --- --- --- --- 49 --- --- --- --- --- --- --- --- 50 --- --- --- --- --- --- --- --- Average 1.37204E+01 4.97018E-03 1.31664E+01 1.25632E-03 0.00000E+00 0.00000E+00 4.16708E+00 4.16801E-04 ------------------------------------------------------------------------------------------------------------------- NOTES: (% Sb) is the percentage of lesions that are strand breaks. The number of Sb is ((% Sb)/100)*(# lesions). The number of Bd is (1-(% Sb)/100)*(# lesions). TABLE 4. Cluster Length (in base pair) =================================================================================================================== Number of --------- DSB ---------- --------- SSB ---------- -------- OTHER --------- ----- ALL CLUSTERS ----- lesions Average SEM Average SEM Average SEM Average SEM =================================================================================================================== 1 --- --- 1.66667E-01 0.00000E+00 1.66667E-01 0.00000E+00 1.66667E-01 0.00000E+00 2 9.10512E-01 9.37980E-04 9.37352E-01 2.50707E-04 9.35589E-01 2.16594E-04 9.35485E-01 1.60990E-04 3 1.60395E+00 1.65791E-03 1.71917E+00 6.12620E-04 1.70629E+00 6.68827E-04 1.70535E+00 4.32657E-04 4 2.34392E+00 3.33571E-03 2.50525E+00 1.37022E-03 2.47658E+00 1.85801E-03 2.47793E+00 1.02170E-03 5 3.09575E+00 6.65524E-03 3.28355E+00 3.02575E-03 3.25269E+00 5.21703E-03 3.24861E+00 2.31689E-03 6 3.84131E+00 1.18109E-02 4.06110E+00 6.77027E-03 4.02698E+00 1.18202E-02 4.01653E+00 5.32983E-03 7 4.62263E+00 2.16100E-02 4.88617E+00 1.33149E-02 4.76467E+00 2.71147E-02 4.81437E+00 1.10840E-02 8 5.32416E+00 3.94830E-02 5.58898E+00 2.57540E-02 5.53740E+00 6.40154E-02 5.51856E+00 2.08640E-02 9 6.25501E+00 7.70144E-02 6.35206E+00 4.92533E-02 6.69620E+00 1.61774E-01 6.34175E+00 4.07503E-02 10 6.76523E+00 1.52001E-01 7.19198E+00 1.04105E-01 6.96667E+00 2.44444E-01 7.03129E+00 8.43314E-02 11 7.86000E+00 3.18224E-01 7.90370E+00 2.12244E-01 8.16667E+00 0.00000E+00 7.89583E+00 1.71374E-01 12 8.66667E+00 6.05530E-01 8.34848E+00 4.12834E-01 --- --- 8.44792E+00 3.31843E-01 13 9.58333E+00 1.41667E+00 9.55556E+00 5.29966E-01 --- --- 9.56667E+00 5.33854E-01 14 9.83333E+00 0.00000E+00 --- --- --- --- 9.83333E+00 0.00000E+00 15 --- --- --- --- --- --- --- --- 16 --- --- --- --- --- --- --- --- 17 --- --- --- --- --- --- --- --- 18 --- --- --- --- --- --- --- --- 19 --- --- --- --- --- --- --- --- 20 --- --- --- --- --- --- --- --- 21 --- --- --- --- --- --- --- --- 22 --- --- --- --- --- --- --- --- 23 --- --- --- --- --- --- --- --- 24 --- --- --- --- --- --- --- --- 25 --- --- --- --- --- --- --- --- 26 --- --- --- --- --- --- --- --- 27 --- --- --- --- --- --- --- --- 28 --- --- --- --- --- --- --- --- 29 --- --- --- --- --- --- --- --- 30 --- --- --- --- --- --- --- --- 31 --- --- --- --- --- --- --- --- 32 --- --- --- --- --- --- --- --- 33 --- --- --- --- --- --- --- --- 34 --- --- --- --- --- --- --- --- 35 --- --- --- --- --- --- --- --- 36 --- --- --- --- --- --- --- --- 37 --- --- --- --- --- --- --- --- 38 --- --- --- --- --- --- --- --- 39 --- --- --- --- --- --- --- --- 40 --- --- --- --- --- --- --- --- 41 --- --- --- --- --- --- --- --- 42 --- --- --- --- --- --- --- --- 43 --- --- --- --- --- --- --- --- 44 --- --- --- --- --- --- --- --- 45 --- --- --- --- --- --- --- --- 46 --- --- --- --- --- --- --- --- 47 --- --- --- --- --- --- --- --- 48 --- --- --- --- --- --- --- --- 49 --- --- --- --- --- --- --- --- 50 --- --- --- --- --- --- --- --- Average 1.49907E+00 1.41423E-03 6.29008E-01 2.16116E-04 3.69370E-01 9.28248E-05 4.62943E-01 9.13956E-05 ------------------------------------------------------------------------------------------------------------------- TABLE 5. NUMBER OF LESIONS DIVIDED BY TWICE THE CLUSTER LENGTH (lesions per nucleotide) =================================================================================================================== Number of --------- DSB ---------- --------- SSB ---------- -------- OTHER --------- ----- ALL CLUSTERS ----- lesions Average SEM Average SEM Average SEM Average SEM =================================================================================================================== 1 --- --- 8.33333E-02 0.00000E+00 8.33333E-02 0.00000E+00 8.33333E-02 0.00000E+00 2 4.55343E-02 7.74145E-05 4.12312E-02 1.69814E-05 4.15490E-02 1.51171E-05 4.15494E-02 1.12107E-05 3 3.17233E-02 4.80242E-05 2.91893E-02 1.57438E-05 2.94630E-02 1.73335E-05 2.94886E-02 1.12982E-05 4 2.71146E-02 5.23152E-05 2.50079E-02 1.91213E-05 2.53667E-02 2.63180E-05 2.53608E-02 1.44974E-05 5 2.47640E-02 6.76265E-05 2.30701E-02 2.72919E-05 2.33417E-02 4.76958E-05 2.33884E-02 2.15470E-05 6 2.34369E-02 8.72869E-05 2.19789E-02 4.50627E-05 2.21439E-02 7.76118E-05 2.22695E-02 3.58868E-05 7 2.24362E-02 1.24387E-04 2.10453E-02 6.73326E-05 2.16241E-02 1.46163E-04 2.14164E-02 5.76843E-05 8 2.20286E-02 1.85552E-04 2.08651E-02 1.12206E-04 2.11068E-02 2.85899E-04 2.11657E-02 9.20452E-05 9 2.09539E-02 2.90927E-04 2.05045E-02 1.74444E-04 1.95535E-02 4.91179E-04 2.05907E-02 1.45896E-04 10 2.17089E-02 6.15496E-04 2.00223E-02 3.24656E-04 2.01843E-02 7.93568E-04 2.06295E-02 2.99355E-04 11 2.01729E-02 7.95421E-04 2.00063E-02 5.96954E-04 1.87075E-02 0.00000E+00 2.00281E-02 4.61599E-04 12 1.96039E-02 1.34274E-03 2.05227E-02 1.14059E-03 --- --- 2.02356E-02 8.70980E-04 13 1.92615E-02 2.84735E-03 1.90190E-02 1.11470E-03 --- --- 1.91160E-02 1.08951E-03 14 1.97740E-02 0.00000E+00 --- --- --- --- 1.97740E-02 0.00000E+00 15 --- --- --- --- --- --- --- --- 16 --- --- --- --- --- --- --- --- 17 --- --- --- --- --- --- --- --- 18 --- --- --- --- --- --- --- --- 19 --- --- --- --- --- --- --- --- 20 --- --- --- --- --- --- --- --- 21 --- --- --- --- --- --- --- --- 22 --- --- --- --- --- --- --- --- 23 --- --- --- --- --- --- --- --- 24 --- --- --- --- --- --- --- --- 25 --- --- --- --- --- --- --- --- 26 --- --- --- --- --- --- --- --- 27 --- --- --- --- --- --- --- --- 28 --- --- --- --- --- --- --- --- 29 --- --- --- --- --- --- --- --- 30 --- --- --- --- --- --- --- --- 31 --- --- --- --- --- --- --- --- 32 --- --- --- --- --- --- --- --- 33 --- --- --- --- --- --- --- --- 34 --- --- --- --- --- --- --- --- 35 --- --- --- --- --- --- --- --- 36 --- --- --- --- --- --- --- --- 37 --- --- --- --- --- --- --- --- 38 --- --- --- --- --- --- --- --- 39 --- --- --- --- --- --- --- --- 40 --- --- --- --- --- --- --- --- 41 --- --- --- --- --- --- --- --- 42 --- --- --- --- --- --- --- --- 43 --- --- --- --- --- --- --- --- 44 --- --- --- --- --- --- --- --- 45 --- --- --- --- --- --- --- --- 46 --- --- --- --- --- --- --- --- 47 --- --- --- --- --- --- --- --- 48 --- --- --- --- --- --- --- --- 49 --- --- --- --- --- --- --- --- 50 --- --- --- --- --- --- --- --- Average 3.73356E-02 4.27631E-05 6.45073E-02 8.16084E-06 7.40512E-02 4.25947E-06 7.06755E-02 3.86220E-06 ------------------------------------------------------------------------------------------------------------------- TABLE 6. Number of clusters per cell per Gy per track. Cluster yields are for a representative cell containing an average of 1.000 Gbp (giga basepair) of DNA. Cluster induction is proportional to absorbed dose up to at least a hundred or thousand Gy. The category "OTHER" includes all classes of individual and clustered DNA lesion, except for SSB and DSB. SEM = standard error of the mean. =================================================================================================================== Number of --------- DSB ---------- --------- SSB ---------- -------- OTHER --------- ----- ALL CLUSTERS ----- lesions Average SEM Average SEM Average SEM Average SEM =================================================================================================================== 1 --- --- 2.07392E-01 5.82584E-05 6.22228E-01 1.07911E-04 8.29620E-01 1.29742E-04 2 7.45372E-03 1.46520E-05 9.35943E-02 4.65560E-05 1.29784E-01 5.35438E-05 2.30832E-01 6.96606E-05 3 4.66377E-03 1.16212E-05 3.24670E-02 2.98393E-05 2.70371E-02 2.67654E-05 6.41679E-02 3.94045E-05 4 1.99844E-03 7.77622E-06 1.01739E-02 1.70241E-05 5.63974E-03 1.27083E-05 1.78121E-02 2.21226E-05 5 7.40075E-04 4.73416E-06 3.02895E-03 9.55875E-06 1.17238E-03 5.96660E-06 4.94140E-03 1.20343E-05 6 2.55632E-04 2.77790E-06 8.66817E-04 5.11187E-06 2.43787E-04 2.68237E-06 1.36624E-03 6.30573E-06 7 8.52209E-05 1.61867E-06 2.40135E-04 2.72602E-06 5.01137E-05 1.24448E-06 3.75469E-04 3.39415E-06 8 2.76500E-05 9.26716E-07 6.61636E-05 1.42341E-06 1.03726E-05 5.64703E-07 1.04186E-04 1.78381E-06 9 8.74612E-06 5.14340E-07 1.98245E-05 7.82598E-07 2.42436E-06 2.71696E-07 3.09950E-05 9.77258E-07 10 2.85400E-06 2.94581E-07 4.84872E-06 3.82703E-07 3.06881E-07 9.70007E-08 8.00960E-06 4.89294E-07 11 7.67203E-07 1.53256E-07 1.38097E-06 2.05409E-07 6.13763E-08 4.33974E-08 2.20955E-06 2.59471E-07 12 1.53441E-07 6.86070E-08 3.37569E-07 1.01730E-07 --- --- 4.91010E-07 1.22660E-07 13 6.13763E-08 4.33974E-08 9.20644E-08 5.31481E-08 --- --- 1.53441E-07 6.86070E-08 14 3.06881E-08 0.00000E+00 --- --- --- --- 3.06881E-08 0.00000E+00 15 --- --- --- --- --- --- --- --- 16 --- --- --- --- --- --- --- --- 17 --- --- --- --- --- --- --- --- 18 --- --- --- --- --- --- --- --- 19 --- --- --- --- --- --- --- --- 20 --- --- --- --- --- --- --- --- 21 --- --- --- --- --- --- --- --- 22 --- --- --- --- --- --- --- --- 23 --- --- --- --- --- --- --- --- 24 --- --- --- --- --- --- --- --- 25 --- --- --- --- --- --- --- --- 26 --- --- --- --- --- --- --- --- 27 --- --- --- --- --- --- --- --- 28 --- --- --- --- --- --- --- --- 29 --- --- --- --- --- --- --- --- 30 --- --- --- --- --- --- --- --- 31 --- --- --- --- --- --- --- --- 32 --- --- --- --- --- --- --- --- 33 --- --- --- --- --- --- --- --- 34 --- --- --- --- --- --- --- --- 35 --- --- --- --- --- --- --- --- 36 --- --- --- --- --- --- --- --- 37 --- --- --- --- --- --- --- --- 38 --- --- --- --- --- --- --- --- 39 --- --- --- --- --- --- --- --- 40 --- --- --- --- --- --- --- --- 41 --- --- --- --- --- --- --- --- 42 --- --- --- --- --- --- --- --- 43 --- --- --- --- --- --- --- --- 44 --- --- --- --- --- --- --- --- 45 --- --- --- --- --- --- --- --- 46 --- --- --- --- --- --- --- --- 47 --- --- --- --- --- --- --- --- 48 --- --- --- --- --- --- --- --- 49 --- --- --- --- --- --- --- --- 50 --- --- --- --- --- --- --- --- Total 1.52371E-02 2.00199E-05 3.47855E-01 4.55512E-05 7.86168E-01 8.08942E-05 1.14926E+00 8.43336E-05 -------------------------------------------------------------------------------------------------------------------