VC 2.00I 15-JUL-2003 01-AUG-2003 04:49:58 PM by RD Stewart (trebor@purdue.edu) PROGRAM FILE INPUT/OUTPUT AND RUN-TIME OPTIONS: ================================================================================ CMD: vc tlk.inp ..\xdat\c3h.xdat -c FNI: tlk.inp FNO: tlk.out RADX: ..\xdat\c3h.radx (139 exposures) XDAT: ..\xdat\c3h.xdat (139 experiments) -------------------------------------------------------------------------------- MCAT SUMMARY: BEST-FIT MODEL PARAMETERS (method = BCONF): ========================================================================================== --- PARAMETER --- ----- CONSTRAINTS ----- INITIAL OPTIMAL PID CID NAM Minimum Maximum GUESS VALUE 2001 CLRP BMR 0.00000E+00 1.00000E-02 2.00000E-04 6.6925972E-04 2400 CLRP PHI 0.00000E+00 2.50000E-01 2.00000E-03 1.0665171E-02 2202 CLRP RHT 1.00000E-02 1.20000E+01 8.00000E+00 8.6513721E+00 1002 IRAD CL 1.00000E+00 4.00000E+01 5.00000E+00 2.0145345E+00 2201 CLRP RHT 1.00000E-02 1.20000E+01 1.50000E-01 1.3592738E-01 ------------------------------------------------------------------------------------------ FIGURE OF MERIT (FOM): 2.99709E-03 (nfom=1056, nsim=146784, nmx=139, nox=139, ndf=133, nap=5) COMBINED UNWEIGHTED RESIDUAL: Stats: min=-1.134E+00 max=7.897E-01, mean=1.5937E-01, stdev=3.8630E-01, var=1.4923E-01 Student's T test (mean=0, NDF=133): Pr>ABS(4.86413)= 3.1960E-06 (reject fit) Shapiro-Wilk's Test: (Pr<0.95794)=2.374E-03 (normality rejected) COMBINED WEIGHTED RESIDUAL: Stats: min=-9.620E-02 max=6.698E-02, mean=1.3518E-02, stdev=3.2765E-02, var=1.0736E-03 Student's T test (mean=0, NDF=133): Pr>ABS(4.86413)= 3.1960E-06 (reject fit) Shapiro-Wilk's Test: (Pr<0.95794)=2.374E-03 (normality rejected) QECK TABLE: Cell and tissue kinetic parameters. ================================================================================ Duration of cell cycle (TCC): 10.00000 h Potential doubling time (Tpot): 480.00000 h (= 20.000 days) Cell birth rate (AX): 1.6636E+00 cell/day (= LOG(2)/TCC) Cell death rate (BX): 1.6289E+00 cell/day [=AX-LOG(2)/TPOT] Net cell birth rate (AX-BX): 3.4657E-02 cell/day Initial Number of Cells: non-dividing: 1.00000E+00 (100.000% = 1-GF) dividing: 0.00000E+00 ( 0.000% = GF) total: 1.00000E+00 (100.000% total) Life Support Capacity of System: Initial system capacity utilization: 0.000000% (=F0) Peak cell density (cells/cm^3): 1.00000E+38 (=KAP) Tissue volume (cm^3): 1.00000E+00 (=VOL) Maximum number of cells (cells): 1.00000E+38 (=KAP*VOL) -------------------------------------------------------------------------------- TLKM TABLE: Summary of TLK parameters and related (derived) quantities. ======================================================================== G0/G1 DNA CONTENT: 5667.000 Mbp/cell = 3.482938E+12 Da/cell ENDOGENOUS DAMAGE: per (h-Da) per (h-Mbp) per (h-cell) Simple DSB = 0.00000E+00 0.00000E+00 0.00000E+00 Complex DSB = 0.00000E+00 0.00000E+00 0.00000E+00 Total DSB = 0.00000E+00 0.00000E+00 0.00000E+00 DAMAGE FORMATION: per (Gy-Da) per (Gy-Mbp) per (Gy-cell) Simple DSB = 8.61342E-12 5.29381E-03 30.000000 Complex DSB = 5.78401E-13 3.55485E-04 2.014535 Total DSB = 9.19182E-12 5.64929E-03 32.014535 DAMAGE REPAIR/MISREPAIR: A1= 7.500000E-01 (=75.000%) A2= 2.500000E-01 (=25.000%) PHI1= 1.066517E-02 (=1.067%) PHI2= 1.066517E-02 (=1.067%) (1-A1)*PHI1= 2.666293E-03 (=0.267%) (1-A2)*PHI2= 7.998879E-03 (=0.800%) (1-A1)*(1-PHI1)= 2.473337E-01 (=24.733%) (1-A2)*(1-PHI2)= 7.420011E-01 (=74.200%) RHT1= 0.135927 h (=8.16 minute) RHT2= 8.651372 h (=519.08 minute) LAM1= 5.0993935E+00 (1/h) LAM2= 8.0119913E-02 (1/h) BMR= 6.6925972E-04 (1/h) LAM1/BMR= 7.6194537E+03 LAM2/BMR= 1.1971423E+02 (LAM1+LAM2)/BMR= 7.7391679E+03 GAM= 0.250 ************** EQUIVALENT LQ MODEL PARAMETERS ************************** Simple Complex Total alpha: 7.9989E-02 + 1.6114E-02 = 9.6102803E-02 (1/Gy) beta: 1.6518E-02 + 6.0126E-03 = 2.2530596E-02 (1/Gy^2) alpha/beta: 4.2654355 (Gy) ------------------------------------------------------------------------ NOTE: 1 bp = 614.6 Da (amu) = 1.0205E-09 pg MCAT FIT: CELL SURVIVAL AS A FUNCTION OF DOSE AND DOSE RATE (C3H 10T1/2 cells). ===================================================================================================== -------- EXPOSURE SUMMARY -------- Duration Dose Dose Rate ---------------- SURVIVING FRACTION -------------- EXPERIMENT (h) (Gy) (Gy/h)* Measured Norm. Wt Predicted Residual ----------------------------------------------------------------------------------------------------- 1 8.3732E+00 5.0239E-01 6.0000E-02 9.25620E-01 7.19E-03 9.51206E-01 2.6898E-02 2 2.8080E+01 1.6848E+00 6.0000E-02 8.66070E-01 7.19E-03 8.41825E-01 -2.8801E-02 3 2.8490E+01 1.7094E+00 6.0000E-02 6.55180E-01 7.19E-03 8.39663E-01 2.1971E-01 4 5.4425E+01 3.2655E+00 6.0000E-02 7.56570E-01 7.19E-03 7.13141E-01 -6.0899E-02 5 5.4833E+01 3.2900E+00 6.0000E-02 5.72340E-01 7.19E-03 7.11305E-01 1.9537E-01 6 9.3432E+01 5.6059E+00 6.0000E-02 8.75570E-01 7.19E-03 5.57450E-01 -5.7067E-01 7 9.3943E+01 5.6366E+00 6.0000E-02 6.17720E-01 7.19E-03 5.55651E-01 -1.1170E-01 8 1.5960E+02 9.5760E+00 6.0000E-02 5.06550E-01 7.19E-03 3.67033E-01 -3.8012E-01 9 1.5981E+02 9.5883E+00 6.0000E-02 4.40580E-01 7.19E-03 3.66558E-01 -2.0194E-01 10 2.4598E+02 1.4759E+01 6.0000E-02 1.93460E-01 7.19E-03 2.12693E-01 9.0427E-02 11 2.4732E+02 1.4839E+01 6.0000E-02 7.81090E-02 7.19E-03 2.10910E-01 6.2966E-01 12 3.3248E+02 1.9949E+01 6.0000E-02 6.89060E-02 7.19E-03 1.23163E-01 4.4053E-01 13 3.3870E+02 2.0322E+01 6.0000E-02 8.50410E-02 7.19E-03 1.18421E-01 2.8188E-01 14 4.1192E+02 2.4715E+01 6.0000E-02 3.47490E-02 7.19E-03 7.45751E-02 5.3404E-01 15 4.1877E+02 2.5126E+01 6.0000E-02 2.82180E-02 7.19E-03 7.14174E-02 6.0489E-01 16 4.9800E+02 2.9880E+01 6.0000E-02 1.63610E-02 7.19E-03 4.32977E-02 6.2213E-01 17 4.9830E+02 2.9898E+01 6.0000E-02 1.32710E-02 7.19E-03 4.32157E-02 6.9291E-01 18 5.7030E+02 3.4218E+01 6.0000E-02 1.25260E-02 7.19E-03 2.74248E-02 5.4326E-01 19 5.7112E+02 3.4267E+01 6.0000E-02 7.16840E-03 7.19E-03 2.72837E-02 7.3726E-01 20 6.6362E+02 3.9817E+01 6.0000E-02 3.62290E-03 7.19E-03 1.52115E-02 7.6183E-01 21 6.6935E+02 4.0161E+01 6.0000E-02 6.33760E-03 7.19E-03 1.46706E-02 5.6801E-01 22 7.4950E+02 4.4970E+01 6.0000E-02 1.96120E-03 7.19E-03 8.84286E-03 7.7822E-01 23 7.5297E+02 4.5178E+01 6.0000E-02 1.59210E-02 7.19E-03 8.65135E-03 -8.4029E-01 24 1.0764E+01 1.8298E+00 1.7000E-01 8.98790E-01 7.19E-03 8.23618E-01 -9.1270E-02 25 2.2349E+01 3.7994E+00 1.7000E-01 6.80190E-01 7.19E-03 6.56356E-01 -3.6312E-02 26 2.2456E+01 3.8176E+00 1.7000E-01 5.49600E-01 7.19E-03 6.54952E-01 1.6085E-01 27 3.3864E+01 5.7568E+00 1.7000E-01 5.93360E-01 7.19E-03 5.20106E-01 -1.4084E-01 28 4.5485E+01 7.7325E+00 1.7000E-01 4.18240E-01 7.19E-03 4.10161E-01 -1.9698E-02 29 4.5557E+01 7.7447E+00 1.7000E-01 3.62830E-01 7.19E-03 4.09558E-01 1.1409E-01 30 5.9359E+01 1.0091E+01 1.7000E-01 3.16870E-01 7.19E-03 3.08535E-01 -2.7016E-02 31 8.9288E+01 1.5179E+01 1.7000E-01 2.25340E-01 7.19E-03 1.66754E-01 -3.5133E-01 32 8.9435E+01 1.5204E+01 1.7000E-01 1.69590E-01 7.19E-03 1.66251E-01 -2.0085E-02 33 1.1482E+02 1.9520E+01 1.7000E-01 1.12080E-01 7.19E-03 9.86278E-02 -1.3639E-01 34 1.1944E+02 2.0304E+01 1.7000E-01 1.04630E-01 7.19E-03 8.97029E-02 -1.6641E-01 35 1.4500E+02 2.4650E+01 1.7000E-01 4.84720E-02 7.19E-03 5.30223E-02 8.5818E-02 36 1.4508E+02 2.4663E+01 1.7000E-01 4.20500E-02 7.19E-03 5.29389E-02 2.0569E-01 37 1.7504E+02 2.9757E+01 1.7000E-01 2.78530E-02 7.19E-03 2.85841E-02 2.5578E-02 38 1.7744E+02 3.0164E+01 1.7000E-01 2.25310E-02 7.19E-03 2.72107E-02 1.7198E-01 39 1.9843E+02 3.3733E+01 1.7000E-01 1.04150E-02 7.19E-03 1.76692E-02 4.1056E-01 40 2.0064E+02 3.4109E+01 1.7000E-01 1.20190E-02 7.19E-03 1.68834E-02 2.8812E-01 41 2.4252E+02 4.1228E+01 1.7000E-01 3.17820E-03 7.19E-03 7.13530E-03 5.5458E-01 42 2.4459E+02 4.1581E+01 1.7000E-01 4.87340E-03 7.19E-03 6.83699E-03 2.8720E-01 43 2.6315E+02 4.4736E+01 1.7000E-01 2.98990E-03 7.19E-03 4.66761E-03 3.5944E-01 44 2.9305E+02 4.9818E+01 1.7000E-01 2.28290E-03 7.19E-03 2.52391E-03 9.5492E-02 45 2.9326E+02 4.9854E+01 1.7000E-01 1.49050E-03 7.19E-03 2.51294E-03 4.0687E-01 46 3.2315E+02 5.4936E+01 1.7000E-01 1.13800E-03 7.19E-03 1.35882E-03 1.6251E-01 47 3.2780E+02 5.5726E+01 1.7000E-01 9.89460E-04 7.19E-03 1.23496E-03 1.9879E-01 48 3.5126E+02 5.9714E+01 1.7000E-01 3.20960E-04 7.19E-03 7.62283E-04 5.7895E-01 49 3.5344E+02 6.0085E+01 1.7000E-01 3.97660E-04 7.19E-03 7.28824E-04 4.5438E-01 50 3.8137E+02 6.4833E+01 1.7000E-01 1.60000E-04 7.19E-03 4.10348E-04 6.1009E-01 51 3.8380E+02 6.5246E+01 1.7000E-01 1.20550E-04 7.19E-03 3.90348E-04 6.9117E-01 52 5.2131E+00 1.5118E+00 2.9000E-01 9.28460E-01 7.19E-03 8.51340E-01 -9.0587E-02 53 7.7676E+00 2.2526E+00 2.9000E-01 9.29390E-01 7.19E-03 7.81473E-01 -1.8928E-01 54 1.4191E+01 4.1154E+00 2.9000E-01 7.12040E-01 7.19E-03 6.22071E-01 -1.4463E-01 55 1.4229E+01 4.1265E+00 2.9000E-01 5.44150E-01 7.19E-03 6.21200E-01 1.2403E-01 56 2.0643E+01 5.9866E+00 2.9000E-01 4.45880E-01 7.19E-03 4.88886E-01 8.7967E-02 57 2.1892E+01 6.3486E+00 2.9000E-01 5.45790E-01 7.19E-03 4.66213E-01 -1.7069E-01 58 2.7010E+01 7.8328E+00 2.9000E-01 5.11330E-01 7.19E-03 3.82963E-01 -3.3520E-01 59 2.7038E+01 7.8411E+00 2.9000E-01 4.17940E-01 7.19E-03 3.82539E-01 -9.2543E-02 60 3.3424E+01 9.6929E+00 2.9000E-01 4.18990E-01 7.19E-03 2.98347E-01 -4.0437E-01 61 3.4683E+01 1.0058E+01 2.9000E-01 4.79520E-01 7.19E-03 2.83999E-01 -6.8846E-01 62 5.1400E+01 1.4906E+01 2.9000E-01 2.15420E-01 7.19E-03 1.46962E-01 -4.6582E-01 63 5.1445E+01 1.4919E+01 2.9000E-01 1.53920E-01 7.19E-03 1.46702E-01 -4.9205E-02 64 6.9366E+01 2.0116E+01 2.9000E-01 1.18460E-01 7.19E-03 7.21447E-02 -6.4198E-01 65 8.0934E+01 2.3471E+01 2.9000E-01 6.94960E-02 7.19E-03 4.56062E-02 -5.2383E-01 66 8.0952E+01 2.3476E+01 2.9000E-01 6.07530E-02 7.19E-03 4.55750E-02 -3.3303E-01 67 1.0414E+02 3.0201E+01 2.9000E-01 1.49410E-02 7.19E-03 1.81709E-02 1.7775E-01 68 1.0416E+02 3.0207E+01 2.9000E-01 1.30610E-02 7.19E-03 1.81560E-02 2.8062E-01 69 1.1952E+02 3.4662E+01 2.9000E-01 1.00420E-02 7.19E-03 9.87304E-03 -1.7113E-02 70 1.1961E+02 3.4687E+01 2.9000E-01 5.48330E-03 7.19E-03 9.83935E-03 4.4272E-01 71 1.3762E+02 3.9910E+01 2.9000E-01 2.15450E-03 7.19E-03 4.81710E-03 5.5274E-01 72 1.3879E+02 4.0250E+01 2.9000E-01 4.51560E-03 7.19E-03 4.59826E-03 1.7976E-02 73 1.5288E+02 4.4335E+01 2.9000E-01 3.47000E-03 7.19E-03 2.63024E-03 -3.1927E-01 74 1.5295E+02 4.4355E+01 2.9000E-01 2.16750E-03 7.19E-03 2.62305E-03 1.7367E-01 75 1.7088E+02 4.9556E+01 2.9000E-01 1.45820E-03 7.19E-03 1.28805E-03 -1.3210E-01 76 1.7096E+02 4.9579E+01 2.9000E-01 8.51650E-04 7.19E-03 1.28400E-03 3.3672E-01 77 1.9013E+02 5.5139E+01 2.9000E-01 7.50130E-04 7.19E-03 6.00304E-04 -2.4958E-01 78 1.9019E+02 5.5156E+01 2.9000E-01 5.01140E-04 7.19E-03 5.98910E-04 1.6325E-01 79 2.1189E+02 6.1449E+01 2.9000E-01 5.40580E-04 7.19E-03 2.53300E-04 -1.1342E+00 80 2.1192E+02 6.1458E+01 2.9000E-01 4.41850E-04 7.19E-03 2.52988E-04 -7.4652E-01 81 2.4283E+02 7.0421E+01 2.9000E-01 7.28110E-05 7.19E-03 7.42692E-05 1.9634E-02 82 2.4291E+02 7.0443E+01 2.9000E-01 4.25240E-05 7.19E-03 7.40461E-05 4.2571E-01 83 2.0498E+00 1.0044E+00 4.9000E-01 7.30490E-01 7.19E-03 8.99498E-01 1.8789E-01 84 6.1622E+00 3.0195E+00 4.9000E-01 7.38780E-01 7.19E-03 7.06866E-01 -4.5148E-02 85 9.5045E+00 4.6572E+00 4.9000E-01 6.46750E-01 7.19E-03 5.69465E-01 -1.3571E-01 86 1.3108E+01 6.4228E+00 4.9000E-01 2.78270E-01 7.19E-03 4.44703E-01 3.7426E-01 87 2.0537E+01 1.0063E+01 4.9000E-01 2.64500E-01 7.19E-03 2.59223E-01 -2.0359E-02 88 2.0588E+01 1.0088E+01 4.9000E-01 2.29470E-01 7.19E-03 2.58239E-01 1.1140E-01 89 2.8892E+01 1.4157E+01 4.9000E-01 1.89660E-01 7.19E-03 1.37594E-01 -3.7840E-01 90 4.9441E+01 2.4226E+01 4.9000E-01 2.21400E-02 7.19E-03 2.78109E-02 2.0391E-01 91 5.0212E+01 2.4604E+01 4.9000E-01 2.55770E-02 7.19E-03 2.61797E-02 2.3021E-02 92 6.1322E+01 3.0048E+01 4.9000E-01 8.45290E-03 7.19E-03 1.09502E-02 2.2806E-01 93 7.2302E+01 3.5428E+01 4.9000E-01 3.98480E-03 7.19E-03 4.62262E-03 1.3798E-01 94 7.2353E+01 3.5453E+01 4.9000E-01 3.45710E-03 7.19E-03 4.60413E-03 2.4913E-01 95 8.2955E+01 4.0648E+01 4.9000E-01 4.86060E-04 7.19E-03 2.00146E-03 7.5715E-01 96 8.3647E+01 4.0987E+01 4.9000E-01 6.94890E-04 7.19E-03 1.89555E-03 6.3341E-01 97 9.3882E+01 4.6002E+01 4.9000E-01 2.64110E-04 7.19E-03 8.48053E-04 6.8857E-01 98 9.3961E+01 4.6041E+01 4.9000E-01 2.13420E-04 7.19E-03 8.42765E-04 7.4676E-01 99 1.0306E+02 5.0499E+01 4.9000E-01 1.89810E-04 7.19E-03 4.12265E-04 5.3959E-01 100 1.0314E+02 5.0538E+01 4.9000E-01 1.53380E-04 7.19E-03 4.09694E-04 6.2562E-01 101 1.1815E+02 5.7895E+01 4.9000E-01 9.04920E-05 7.19E-03 1.25888E-04 2.8117E-01 102 1.1849E+02 5.8061E+01 4.9000E-01 3.59400E-05 7.19E-03 1.22581E-04 7.0681E-01 103 1.2422E+02 6.0869E+01 4.9000E-01 3.92000E-05 7.19E-03 7.81306E-05 4.9828E-01 104 1.2433E+02 6.0920E+01 4.9000E-01 2.95040E-05 7.19E-03 7.74941E-05 6.1927E-01 105 1.3255E+02 6.4951E+01 4.9000E-01 3.01770E-05 7.19E-03 4.05952E-05 2.5664E-01 106 1.3273E+02 6.5040E+01 4.9000E-01 1.83540E-05 7.19E-03 4.00198E-05 5.4138E-01 107 3.0745E-01 7.3787E-01 2.4000E+00 6.28280E-01 7.19E-03 9.22698E-01 3.1908E-01 108 6.3938E-01 1.5345E+00 2.4000E+00 7.80370E-01 7.19E-03 8.35914E-01 6.6447E-02 109 9.8492E-01 2.3638E+00 2.4000E+00 6.77940E-01 7.19E-03 7.47989E-01 9.3650E-02 110 9.9579E-01 2.3899E+00 2.4000E+00 5.09310E-01 7.19E-03 7.45288E-01 3.1663E-01 111 2.0243E+00 4.8582E+00 2.4000E+00 4.13820E-01 7.19E-03 5.13673E-01 1.9439E-01 112 2.0324E+00 4.8777E+00 2.4000E+00 3.33930E-01 7.19E-03 5.12051E-01 3.4786E-01 113 3.7519E+00 9.0046E+00 2.4000E+00 2.04770E-01 7.19E-03 2.44854E-01 1.6371E-01 114 3.7710E+00 9.0503E+00 2.4000E+00 1.24140E-01 7.19E-03 2.42693E-01 4.8849E-01 115 5.8604E+00 1.4065E+01 2.4000E+00 3.47470E-02 7.19E-03 8.49533E-02 5.9099E-01 116 6.0088E+00 1.4421E+01 2.4000E+00 6.16360E-02 7.19E-03 7.84462E-02 2.1429E-01 117 7.0700E+00 1.6968E+01 2.4000E+00 2.12340E-02 7.19E-03 4.36117E-02 5.1311E-01 118 7.0779E+00 1.6987E+01 2.4000E+00 1.71350E-02 7.19E-03 4.34165E-02 6.0533E-01 119 8.1417E+00 1.9540E+01 2.4000E+00 5.49580E-03 7.19E-03 2.34635E-02 7.6577E-01 120 8.3200E+00 1.9968E+01 2.4000E+00 4.43990E-03 7.19E-03 2.11141E-02 7.8972E-01 121 9.3404E+00 2.2417E+01 2.4000E+00 4.47050E-03 7.19E-03 1.14125E-02 6.0828E-01 122 9.4913E+00 2.2779E+01 2.4000E+00 7.38270E-03 7.19E-03 1.04041E-02 2.9041E-01 123 1.0377E+01 2.4905E+01 2.4000E+00 2.93110E-03 7.19E-03 5.99902E-03 5.1140E-01 124 1.0533E+01 2.5280E+01 2.4000E+00 4.19550E-03 7.19E-03 5.43711E-03 2.2836E-01 125 1.2645E+01 3.0347E+01 2.4000E+00 6.62810E-04 7.19E-03 1.39555E-03 5.2506E-01 126 1.2669E+01 3.0406E+01 2.4000E+00 3.48280E-04 7.19E-03 1.37321E-03 7.4638E-01 127 1.4861E+01 3.5666E+01 2.4000E+00 5.83100E-04 7.19E-03 3.18333E-04 -8.3173E-01 128 1.4880E+01 3.5711E+01 2.4000E+00 3.53490E-04 7.19E-03 3.14321E-04 -1.2461E-01 129 4.1378E-03 2.2758E-01 5.5000E+01 8.30830E-01 7.19E-03 9.77031E-01 1.4964E-01 130 1.2357E-02 6.7963E-01 5.5000E+01 5.47590E-01 7.19E-03 9.26694E-01 4.0909E-01 131 3.2933E-02 1.8113E+00 5.5000E+01 8.36320E-01 7.19E-03 7.82010E-01 -6.9450E-02 132 4.8011E-02 2.6406E+00 5.5000E+01 6.34780E-01 7.19E-03 6.69024E-01 5.1185E-02 133 6.9607E-02 3.8284E+00 5.5000E+01 6.37930E-01 7.19E-03 5.12659E-01 -2.4435E-01 134 9.1884E-02 5.0536E+00 5.5000E+01 4.85000E-01 7.19E-03 3.71224E-01 -3.0649E-01 135 1.2340E-01 6.7869E+00 5.5000E+01 1.59920E-01 7.19E-03 2.18176E-01 2.6701E-01 136 1.6143E-01 8.8788E+00 5.5000E+01 6.98120E-02 7.19E-03 1.03696E-01 3.2676E-01 137 2.0565E-01 1.1311E+01 5.5000E+01 4.63940E-02 7.19E-03 3.87205E-02 -1.9818E-01 138 2.8240E-01 1.5532E+01 5.5000E+01 6.68910E-03 7.19E-03 5.45880E-03 -2.2538E-01 139 3.6118E-01 1.9865E+01 5.5000E+01 4.17580E-04 7.19E-03 5.64064E-04 2.5969E-01 ----------------------------------------------------------------------------------------------------- RESIDUAL: Stats: min=-1.134E+00 max=7.897E-01, mean=1.5937E-01, stdev=3.8630E-01, var=1.4923E-01 Student's T test (mean=0, NDF=133): Pr>ABS(4.86413)= 3.1960E-06 (reject fit) Shapiro-Wilk's Test: (Pr<0.95794)=2.374E-03 (normality rejected) WEIGHTED RESIDUAL: Stats: min=-9.620E-02 max=6.698E-02, mean=1.3518E-02, stdev=3.2765E-02, var=1.0736E-03 Student's T test (mean=0, NDF=133): Pr>ABS(4.86413)= 3.1960E-06 (reject fit) Shapiro-Wilk's Test: (Pr<0.95794)=2.374E-03 (normality rejected) NOX=139, NPAR=5 CFE.SF: Cell survival data for C3H 10T1/2 cells. ========================================================================================= -------- EXPOSURE SUMMARY -------- ------------ ENDPOINT ------------- DATASET ID Duration Dose Dose Rate Fraction Fraction Standard CFE RADX (h) (Gy) (Gy/h) Killed Viable Error (%) ----------------------------------------------------------------------------------------- 1 1 8.3732E+00 5.0239E-01 6.0000E-02 7.43800E-02 9.25620E-01 1.00E+01 2 2 2.8080E+01 1.6848E+00 6.0000E-02 1.33930E-01 8.66070E-01 1.00E+01 3 3 2.8490E+01 1.7094E+00 6.0000E-02 3.44820E-01 6.55180E-01 1.00E+01 4 4 5.4425E+01 3.2655E+00 6.0000E-02 2.43430E-01 7.56570E-01 1.00E+01 5 5 5.4833E+01 3.2900E+00 6.0000E-02 4.27660E-01 5.72340E-01 1.00E+01 6 6 9.3432E+01 5.6059E+00 6.0000E-02 1.24430E-01 8.75570E-01 1.00E+01 7 7 9.3943E+01 5.6366E+00 6.0000E-02 3.82280E-01 6.17720E-01 1.00E+01 8 8 1.5960E+02 9.5760E+00 6.0000E-02 4.93450E-01 5.06550E-01 1.00E+01 9 9 1.5981E+02 9.5883E+00 6.0000E-02 5.59420E-01 4.40580E-01 1.00E+01 10 10 2.4598E+02 1.4759E+01 6.0000E-02 8.06540E-01 1.93460E-01 1.00E+01 11 11 2.4732E+02 1.4839E+01 6.0000E-02 9.21891E-01 7.81090E-02 1.00E+01 12 12 3.3248E+02 1.9949E+01 6.0000E-02 9.31094E-01 6.89060E-02 1.00E+01 13 13 3.3870E+02 2.0322E+01 6.0000E-02 9.14959E-01 8.50410E-02 1.00E+01 14 14 4.1192E+02 2.4715E+01 6.0000E-02 9.65251E-01 3.47490E-02 1.00E+01 15 15 4.1877E+02 2.5126E+01 6.0000E-02 9.71782E-01 2.82180E-02 1.00E+01 16 16 4.9800E+02 2.9880E+01 6.0000E-02 9.83639E-01 1.63610E-02 1.00E+01 17 17 4.9830E+02 2.9898E+01 6.0000E-02 9.86729E-01 1.32710E-02 1.00E+01 18 18 5.7030E+02 3.4218E+01 6.0000E-02 9.87474E-01 1.25260E-02 1.00E+01 19 19 5.7112E+02 3.4267E+01 6.0000E-02 9.92832E-01 7.16840E-03 1.00E+01 20 20 6.6362E+02 3.9817E+01 6.0000E-02 9.96377E-01 3.62290E-03 1.00E+01 21 21 6.6935E+02 4.0161E+01 6.0000E-02 9.93662E-01 6.33760E-03 1.00E+01 22 22 7.4950E+02 4.4970E+01 6.0000E-02 9.98039E-01 1.96120E-03 1.00E+01 23 23 7.5297E+02 4.5178E+01 6.0000E-02 9.84079E-01 1.59210E-02 1.00E+01 24 24 1.0764E+01 1.8298E+00 1.7000E-01 1.01210E-01 8.98790E-01 1.00E+01 25 25 2.2349E+01 3.7994E+00 1.7000E-01 3.19810E-01 6.80190E-01 1.00E+01 26 26 2.2456E+01 3.8176E+00 1.7000E-01 4.50400E-01 5.49600E-01 1.00E+01 27 27 3.3864E+01 5.7568E+00 1.7000E-01 4.06640E-01 5.93360E-01 1.00E+01 28 28 4.5485E+01 7.7325E+00 1.7000E-01 5.81760E-01 4.18240E-01 1.00E+01 29 29 4.5557E+01 7.7447E+00 1.7000E-01 6.37170E-01 3.62830E-01 1.00E+01 30 30 5.9359E+01 1.0091E+01 1.7000E-01 6.83130E-01 3.16870E-01 1.00E+01 31 31 8.9288E+01 1.5179E+01 1.7000E-01 7.74660E-01 2.25340E-01 1.00E+01 32 32 8.9435E+01 1.5204E+01 1.7000E-01 8.30410E-01 1.69590E-01 1.00E+01 33 33 1.1482E+02 1.9520E+01 1.7000E-01 8.87920E-01 1.12080E-01 1.00E+01 34 34 1.1944E+02 2.0304E+01 1.7000E-01 8.95370E-01 1.04630E-01 1.00E+01 35 35 1.4500E+02 2.4650E+01 1.7000E-01 9.51528E-01 4.84720E-02 1.00E+01 36 36 1.4508E+02 2.4663E+01 1.7000E-01 9.57950E-01 4.20500E-02 1.00E+01 37 37 1.7504E+02 2.9757E+01 1.7000E-01 9.72147E-01 2.78530E-02 1.00E+01 38 38 1.7744E+02 3.0164E+01 1.7000E-01 9.77469E-01 2.25310E-02 1.00E+01 39 39 1.9843E+02 3.3733E+01 1.7000E-01 9.89585E-01 1.04150E-02 1.00E+01 40 40 2.0064E+02 3.4109E+01 1.7000E-01 9.87981E-01 1.20190E-02 1.00E+01 41 41 2.4252E+02 4.1228E+01 1.7000E-01 9.96822E-01 3.17820E-03 1.00E+01 42 42 2.4459E+02 4.1581E+01 1.7000E-01 9.95127E-01 4.87340E-03 1.00E+01 43 43 2.6315E+02 4.4736E+01 1.7000E-01 9.97010E-01 2.98990E-03 1.00E+01 44 44 2.9305E+02 4.9818E+01 1.7000E-01 9.97717E-01 2.28290E-03 1.00E+01 45 45 2.9326E+02 4.9854E+01 1.7000E-01 9.98510E-01 1.49050E-03 1.00E+01 46 46 3.2315E+02 5.4936E+01 1.7000E-01 9.98862E-01 1.13800E-03 1.00E+01 47 47 3.2780E+02 5.5726E+01 1.7000E-01 9.99011E-01 9.89460E-04 1.00E+01 48 48 3.5126E+02 5.9714E+01 1.7000E-01 9.99679E-01 3.20960E-04 1.00E+01 49 49 3.5344E+02 6.0085E+01 1.7000E-01 9.99602E-01 3.97660E-04 1.00E+01 50 50 3.8137E+02 6.4833E+01 1.7000E-01 9.99840E-01 1.60000E-04 1.00E+01 51 51 3.8380E+02 6.5246E+01 1.7000E-01 9.99879E-01 1.20550E-04 1.00E+01 52 52 5.2131E+00 1.5118E+00 2.9000E-01 7.15400E-02 9.28460E-01 1.00E+01 53 53 7.7676E+00 2.2526E+00 2.9000E-01 7.06100E-02 9.29390E-01 1.00E+01 54 54 1.4191E+01 4.1154E+00 2.9000E-01 2.87960E-01 7.12040E-01 1.00E+01 55 55 1.4229E+01 4.1265E+00 2.9000E-01 4.55850E-01 5.44150E-01 1.00E+01 56 56 2.0643E+01 5.9866E+00 2.9000E-01 5.54120E-01 4.45880E-01 1.00E+01 57 57 2.1892E+01 6.3486E+00 2.9000E-01 4.54210E-01 5.45790E-01 1.00E+01 58 58 2.7010E+01 7.8328E+00 2.9000E-01 4.88670E-01 5.11330E-01 1.00E+01 59 59 2.7038E+01 7.8411E+00 2.9000E-01 5.82060E-01 4.17940E-01 1.00E+01 60 60 3.3424E+01 9.6929E+00 2.9000E-01 5.81010E-01 4.18990E-01 1.00E+01 61 61 3.4683E+01 1.0058E+01 2.9000E-01 5.20480E-01 4.79520E-01 1.00E+01 62 62 5.1400E+01 1.4906E+01 2.9000E-01 7.84580E-01 2.15420E-01 1.00E+01 63 63 5.1445E+01 1.4919E+01 2.9000E-01 8.46080E-01 1.53920E-01 1.00E+01 64 64 6.9366E+01 2.0116E+01 2.9000E-01 8.81540E-01 1.18460E-01 1.00E+01 65 65 8.0934E+01 2.3471E+01 2.9000E-01 9.30504E-01 6.94960E-02 1.00E+01 66 66 8.0952E+01 2.3476E+01 2.9000E-01 9.39247E-01 6.07530E-02 1.00E+01 67 67 1.0414E+02 3.0201E+01 2.9000E-01 9.85059E-01 1.49410E-02 1.00E+01 68 68 1.0416E+02 3.0207E+01 2.9000E-01 9.86939E-01 1.30610E-02 1.00E+01 69 69 1.1952E+02 3.4662E+01 2.9000E-01 9.89958E-01 1.00420E-02 1.00E+01 70 70 1.1961E+02 3.4687E+01 2.9000E-01 9.94517E-01 5.48330E-03 1.00E+01 71 71 1.3762E+02 3.9910E+01 2.9000E-01 9.97846E-01 2.15450E-03 1.00E+01 72 72 1.3879E+02 4.0250E+01 2.9000E-01 9.95484E-01 4.51560E-03 1.00E+01 73 73 1.5288E+02 4.4335E+01 2.9000E-01 9.96530E-01 3.47000E-03 1.00E+01 74 74 1.5295E+02 4.4355E+01 2.9000E-01 9.97833E-01 2.16750E-03 1.00E+01 75 75 1.7088E+02 4.9556E+01 2.9000E-01 9.98542E-01 1.45820E-03 1.00E+01 76 76 1.7096E+02 4.9579E+01 2.9000E-01 9.99148E-01 8.51650E-04 1.00E+01 77 77 1.9013E+02 5.5139E+01 2.9000E-01 9.99250E-01 7.50130E-04 1.00E+01 78 78 1.9019E+02 5.5156E+01 2.9000E-01 9.99499E-01 5.01140E-04 1.00E+01 79 79 2.1189E+02 6.1449E+01 2.9000E-01 9.99459E-01 5.40580E-04 1.00E+01 80 80 2.1192E+02 6.1458E+01 2.9000E-01 9.99558E-01 4.41850E-04 1.00E+01 81 81 2.4283E+02 7.0421E+01 2.9000E-01 9.99927E-01 7.28110E-05 1.00E+01 82 82 2.4291E+02 7.0443E+01 2.9000E-01 9.99957E-01 4.25240E-05 1.00E+01 83 83 2.0498E+00 1.0044E+00 4.9000E-01 2.69510E-01 7.30490E-01 1.00E+01 84 84 6.1622E+00 3.0195E+00 4.9000E-01 2.61220E-01 7.38780E-01 1.00E+01 85 85 9.5045E+00 4.6572E+00 4.9000E-01 3.53250E-01 6.46750E-01 1.00E+01 86 86 1.3108E+01 6.4228E+00 4.9000E-01 7.21730E-01 2.78270E-01 1.00E+01 87 87 2.0537E+01 1.0063E+01 4.9000E-01 7.35500E-01 2.64500E-01 1.00E+01 88 88 2.0588E+01 1.0088E+01 4.9000E-01 7.70530E-01 2.29470E-01 1.00E+01 89 89 2.8892E+01 1.4157E+01 4.9000E-01 8.10340E-01 1.89660E-01 1.00E+01 90 90 4.9441E+01 2.4226E+01 4.9000E-01 9.77860E-01 2.21400E-02 1.00E+01 91 91 5.0212E+01 2.4604E+01 4.9000E-01 9.74423E-01 2.55770E-02 1.00E+01 92 92 6.1322E+01 3.0048E+01 4.9000E-01 9.91547E-01 8.45290E-03 1.00E+01 93 93 7.2302E+01 3.5428E+01 4.9000E-01 9.96015E-01 3.98480E-03 1.00E+01 94 94 7.2353E+01 3.5453E+01 4.9000E-01 9.96543E-01 3.45710E-03 1.00E+01 95 95 8.2955E+01 4.0648E+01 4.9000E-01 9.99514E-01 4.86060E-04 1.00E+01 96 96 8.3647E+01 4.0987E+01 4.9000E-01 9.99305E-01 6.94890E-04 1.00E+01 97 97 9.3882E+01 4.6002E+01 4.9000E-01 9.99736E-01 2.64110E-04 1.00E+01 98 98 9.3961E+01 4.6041E+01 4.9000E-01 9.99787E-01 2.13420E-04 1.00E+01 99 99 1.0306E+02 5.0499E+01 4.9000E-01 9.99810E-01 1.89810E-04 1.00E+01 100 100 1.0314E+02 5.0538E+01 4.9000E-01 9.99847E-01 1.53380E-04 1.00E+01 101 101 1.1815E+02 5.7895E+01 4.9000E-01 9.99910E-01 9.04920E-05 1.00E+01 102 102 1.1849E+02 5.8061E+01 4.9000E-01 9.99964E-01 3.59400E-05 1.00E+01 103 103 1.2422E+02 6.0869E+01 4.9000E-01 9.99961E-01 3.92000E-05 1.00E+01 104 104 1.2433E+02 6.0920E+01 4.9000E-01 9.99970E-01 2.95040E-05 1.00E+01 105 105 1.3255E+02 6.4951E+01 4.9000E-01 9.99970E-01 3.01770E-05 1.00E+01 106 106 1.3273E+02 6.5040E+01 4.9000E-01 9.99982E-01 1.83540E-05 1.00E+01 107 107 3.0745E-01 7.3787E-01 2.4000E+00 3.71720E-01 6.28280E-01 1.00E+01 108 108 6.3938E-01 1.5345E+00 2.4000E+00 2.19630E-01 7.80370E-01 1.00E+01 109 109 9.8492E-01 2.3638E+00 2.4000E+00 3.22060E-01 6.77940E-01 1.00E+01 110 110 9.9579E-01 2.3899E+00 2.4000E+00 4.90690E-01 5.09310E-01 1.00E+01 111 111 2.0243E+00 4.8582E+00 2.4000E+00 5.86180E-01 4.13820E-01 1.00E+01 112 112 2.0324E+00 4.8777E+00 2.4000E+00 6.66070E-01 3.33930E-01 1.00E+01 113 113 3.7519E+00 9.0046E+00 2.4000E+00 7.95230E-01 2.04770E-01 1.00E+01 114 114 3.7710E+00 9.0503E+00 2.4000E+00 8.75860E-01 1.24140E-01 1.00E+01 115 115 5.8604E+00 1.4065E+01 2.4000E+00 9.65253E-01 3.47470E-02 1.00E+01 116 116 6.0088E+00 1.4421E+01 2.4000E+00 9.38364E-01 6.16360E-02 1.00E+01 117 117 7.0700E+00 1.6968E+01 2.4000E+00 9.78766E-01 2.12340E-02 1.00E+01 118 118 7.0779E+00 1.6987E+01 2.4000E+00 9.82865E-01 1.71350E-02 1.00E+01 119 119 8.1417E+00 1.9540E+01 2.4000E+00 9.94504E-01 5.49580E-03 1.00E+01 120 120 8.3200E+00 1.9968E+01 2.4000E+00 9.95560E-01 4.43990E-03 1.00E+01 121 121 9.3404E+00 2.2417E+01 2.4000E+00 9.95529E-01 4.47050E-03 1.00E+01 122 122 9.4913E+00 2.2779E+01 2.4000E+00 9.92617E-01 7.38270E-03 1.00E+01 123 123 1.0377E+01 2.4905E+01 2.4000E+00 9.97069E-01 2.93110E-03 1.00E+01 124 124 1.0533E+01 2.5280E+01 2.4000E+00 9.95804E-01 4.19550E-03 1.00E+01 125 125 1.2645E+01 3.0347E+01 2.4000E+00 9.99337E-01 6.62810E-04 1.00E+01 126 126 1.2669E+01 3.0406E+01 2.4000E+00 9.99652E-01 3.48280E-04 1.00E+01 127 127 1.4861E+01 3.5666E+01 2.4000E+00 9.99417E-01 5.83100E-04 1.00E+01 128 128 1.4880E+01 3.5711E+01 2.4000E+00 9.99647E-01 3.53490E-04 1.00E+01 129 129 4.1378E-03 2.2758E-01 5.5000E+01 1.69170E-01 8.30830E-01 1.00E+01 130 130 1.2357E-02 6.7963E-01 5.5000E+01 4.52410E-01 5.47590E-01 1.00E+01 131 131 3.2933E-02 1.8113E+00 5.5000E+01 1.63680E-01 8.36320E-01 1.00E+01 132 132 4.8011E-02 2.6406E+00 5.5000E+01 3.65220E-01 6.34780E-01 1.00E+01 133 133 6.9607E-02 3.8284E+00 5.5000E+01 3.62070E-01 6.37930E-01 1.00E+01 134 134 9.1884E-02 5.0536E+00 5.5000E+01 5.15000E-01 4.85000E-01 1.00E+01 135 135 1.2340E-01 6.7869E+00 5.5000E+01 8.40080E-01 1.59920E-01 1.00E+01 136 136 1.6143E-01 8.8788E+00 5.5000E+01 9.30188E-01 6.98120E-02 1.00E+01 137 137 2.0565E-01 1.1311E+01 5.5000E+01 9.53606E-01 4.63940E-02 1.00E+01 138 138 2.8240E-01 1.5532E+01 5.5000E+01 9.93311E-01 6.68910E-03 1.00E+01 139 139 3.6118E-01 1.9865E+01 5.5000E+01 9.99582E-01 4.17580E-04 1.00E+01 ----------------------------------------------------------------------------------------- CFE.DXA: Additional details from the cell survival assay (C3H 10T1/2). ===================================================================================== DATASET ID ---------- TIME (h) ----------- DOSE ---- LETHAL DAMAGE --- CFE RADX RADX TTP ETSI (Gy) #/(cell Gy) #/(cell) ------------------------------------------------------------------------------------- 1 1 8.373E+00 1.200E+01 4.000E+02 5.0239E-01 1.5385E-01 7.7291E-02 2 2 2.808E+01 1.200E+01 4.000E+02 1.6848E+00 8.5345E-02 1.4379E-01 3 3 2.849E+01 1.200E+01 4.000E+02 1.7094E+00 2.4736E-01 4.2285E-01 4 4 5.442E+01 1.200E+01 4.000E+02 3.2655E+00 8.5426E-02 2.7896E-01 5 5 5.483E+01 1.200E+01 4.000E+02 3.2900E+00 1.6961E-01 5.5802E-01 6 6 9.343E+01 1.200E+01 4.000E+02 5.6059E+00 2.3704E-02 1.3288E-01 7 7 9.394E+01 1.200E+01 4.000E+02 5.6366E+00 8.5463E-02 4.8172E-01 8 8 1.596E+02 1.200E+01 4.000E+02 9.5760E+00 7.1025E-02 6.8013E-01 9 9 1.598E+02 1.200E+01 4.000E+02 9.5883E+00 8.5486E-02 8.1966E-01 10 10 2.460E+02 1.200E+01 4.000E+02 1.4759E+01 1.1130E-01 1.6427E+00 11 11 2.473E+02 1.200E+01 4.000E+02 1.4839E+01 1.7182E-01 2.5496E+00 12 12 3.325E+02 1.200E+01 4.000E+02 1.9949E+01 1.3409E-01 2.6750E+00 13 13 3.387E+02 1.200E+01 4.000E+02 2.0322E+01 1.2128E-01 2.4646E+00 14 14 4.119E+02 1.200E+01 4.000E+02 2.4715E+01 1.3593E-01 3.3596E+00 15 15 4.188E+02 1.200E+01 4.000E+02 2.5126E+01 1.4200E-01 3.5678E+00 16 16 4.980E+02 1.200E+01 4.000E+02 2.9880E+01 1.3765E-01 4.1129E+00 17 17 4.983E+02 1.200E+01 4.000E+02 2.9898E+01 1.4456E-01 4.3222E+00 18 18 5.703E+02 1.200E+01 4.000E+02 3.4218E+01 1.2800E-01 4.3799E+00 19 19 5.711E+02 1.200E+01 4.000E+02 3.4267E+01 1.4411E-01 4.9381E+00 20 20 6.636E+02 1.200E+01 4.000E+02 3.9817E+01 1.4116E-01 5.6205E+00 21 21 6.694E+02 1.200E+01 4.000E+02 4.0161E+01 1.2602E-01 5.0613E+00 22 22 7.495E+02 1.200E+01 4.000E+02 4.4970E+01 1.3863E-01 6.2342E+00 23 23 7.530E+02 1.200E+01 4.000E+02 4.5178E+01 9.1640E-02 4.1401E+00 24 24 1.076E+01 1.200E+01 4.000E+02 1.8298E+00 5.8316E-02 1.0671E-01 25 25 2.235E+01 1.200E+01 4.000E+02 3.7994E+00 1.0143E-01 3.8538E-01 26 26 2.246E+01 1.200E+01 4.000E+02 3.8176E+00 1.5679E-01 5.9856E-01 27 27 3.386E+01 1.200E+01 4.000E+02 5.7568E+00 9.0667E-02 5.2195E-01 28 28 4.549E+01 1.200E+01 4.000E+02 7.7325E+00 1.1273E-01 8.7170E-01 29 29 4.556E+01 1.200E+01 4.000E+02 7.7447E+00 1.3091E-01 1.0138E+00 30 30 5.936E+01 1.200E+01 4.000E+02 1.0091E+01 1.1389E-01 1.1493E+00 31 31 8.929E+01 1.200E+01 4.000E+02 1.5179E+01 9.8171E-02 1.4901E+00 32 32 8.944E+01 1.200E+01 4.000E+02 1.5204E+01 1.1670E-01 1.7744E+00 33 33 1.148E+02 1.200E+01 4.000E+02 1.9520E+01 1.1212E-01 2.1885E+00 34 34 1.194E+02 1.200E+01 4.000E+02 2.0304E+01 1.1118E-01 2.2573E+00 35 35 1.450E+02 1.200E+01 4.000E+02 2.4650E+01 1.2279E-01 3.0268E+00 36 36 1.451E+02 1.200E+01 4.000E+02 2.4663E+01 1.2849E-01 3.1689E+00 37 37 1.750E+02 1.200E+01 4.000E+02 2.9757E+01 1.2034E-01 3.5808E+00 38 38 1.774E+02 1.200E+01 4.000E+02 3.0164E+01 1.2574E-01 3.7929E+00 39 39 1.984E+02 1.200E+01 4.000E+02 3.3733E+01 1.3531E-01 4.5645E+00 40 40 2.006E+02 1.200E+01 4.000E+02 3.4109E+01 1.2962E-01 4.4213E+00 41 41 2.425E+02 1.200E+01 4.000E+02 4.1228E+01 1.3950E-01 5.7514E+00 42 42 2.446E+02 1.200E+01 4.000E+02 4.1581E+01 1.2804E-01 5.3240E+00 43 43 2.632E+02 1.200E+01 4.000E+02 4.4736E+01 1.2993E-01 5.8125E+00 44 44 2.930E+02 1.200E+01 4.000E+02 4.9818E+01 1.2209E-01 6.0823E+00 45 45 2.933E+02 1.200E+01 4.000E+02 4.9854E+01 1.3055E-01 6.5086E+00 46 46 3.232E+02 1.200E+01 4.000E+02 5.4936E+01 1.2339E-01 6.7785E+00 47 47 3.278E+02 1.200E+01 4.000E+02 5.5726E+01 1.2415E-01 6.9184E+00 48 48 3.513E+02 1.200E+01 4.000E+02 5.9714E+01 1.3471E-01 8.0442E+00 49 49 3.534E+02 1.200E+01 4.000E+02 6.0085E+01 1.3031E-01 7.8299E+00 50 50 3.814E+02 1.200E+01 4.000E+02 6.4833E+01 1.3481E-01 8.7403E+00 51 51 3.838E+02 1.200E+01 4.000E+02 6.5246E+01 1.3830E-01 9.0234E+00 52 52 5.213E+00 1.200E+01 4.000E+02 1.5118E+00 4.9099E-02 7.4228E-02 53 53 7.768E+00 1.200E+01 4.000E+02 2.2526E+00 3.2508E-02 7.3227E-02 54 54 1.419E+01 1.200E+01 4.000E+02 4.1154E+00 8.2524E-02 3.3962E-01 55 55 1.423E+01 1.200E+01 4.000E+02 4.1265E+00 1.4747E-01 6.0853E-01 56 56 2.064E+01 1.200E+01 4.000E+02 5.9866E+00 1.3492E-01 8.0771E-01 57 57 2.189E+01 1.200E+01 4.000E+02 6.3486E+00 9.5379E-02 6.0552E-01 58 58 2.701E+01 1.200E+01 4.000E+02 7.8328E+00 8.5632E-02 6.7074E-01 59 59 2.704E+01 1.200E+01 4.000E+02 7.8411E+00 1.1126E-01 8.7242E-01 60 60 3.342E+01 1.200E+01 4.000E+02 9.6929E+00 8.9747E-02 8.6991E-01 61 61 3.468E+01 1.200E+01 4.000E+02 1.0058E+01 7.3073E-02 7.3497E-01 62 62 5.140E+01 1.200E+01 4.000E+02 1.4906E+01 1.0299E-01 1.5352E+00 63 63 5.144E+01 1.200E+01 4.000E+02 1.4919E+01 1.2543E-01 1.8713E+00 64 64 6.937E+01 1.200E+01 4.000E+02 2.0116E+01 1.0604E-01 2.1332E+00 65 65 8.093E+01 1.200E+01 4.000E+02 2.3471E+01 1.1361E-01 2.6665E+00 66 66 8.095E+01 1.200E+01 4.000E+02 2.3476E+01 1.1931E-01 2.8009E+00 67 67 1.041E+02 1.200E+01 4.000E+02 3.0201E+01 1.3919E-01 4.2036E+00 68 68 1.042E+02 1.200E+01 4.000E+02 3.0207E+01 1.4361E-01 4.3381E+00 69 69 1.195E+02 1.200E+01 4.000E+02 3.4662E+01 1.3274E-01 4.6010E+00 70 70 1.196E+02 1.200E+01 4.000E+02 3.4687E+01 1.5009E-01 5.2060E+00 71 71 1.376E+02 1.200E+01 4.000E+02 3.9910E+01 1.5385E-01 6.1402E+00 72 72 1.388E+02 1.200E+01 4.000E+02 4.0250E+01 1.3417E-01 5.4002E+00 73 73 1.529E+02 1.200E+01 4.000E+02 4.4335E+01 1.2775E-01 5.6636E+00 74 74 1.529E+02 1.200E+01 4.000E+02 4.4355E+01 1.3830E-01 6.1342E+00 75 75 1.709E+02 1.200E+01 4.000E+02 4.9556E+01 1.3178E-01 6.5306E+00 76 76 1.710E+02 1.200E+01 4.000E+02 4.9579E+01 1.4257E-01 7.0683E+00 77 77 1.901E+02 1.200E+01 4.000E+02 5.5139E+01 1.3049E-01 7.1953E+00 78 78 1.902E+02 1.200E+01 4.000E+02 5.5156E+01 1.3777E-01 7.5986E+00 79 79 2.119E+02 1.200E+01 4.000E+02 6.1449E+01 1.2242E-01 7.5229E+00 80 80 2.119E+02 1.200E+01 4.000E+02 6.1458E+01 1.2569E-01 7.7245E+00 81 81 2.428E+02 1.200E+01 4.000E+02 7.0421E+01 1.3530E-01 9.5276E+00 82 82 2.429E+02 1.200E+01 4.000E+02 7.0443E+01 1.4289E-01 1.0065E+01 83 83 2.050E+00 1.200E+01 4.000E+02 1.0044E+00 3.1266E-01 3.1404E-01 84 84 6.162E+00 1.200E+01 4.000E+02 3.0195E+00 1.0027E-01 3.0276E-01 85 85 9.504E+00 1.200E+01 4.000E+02 4.6572E+00 9.3575E-02 4.3580E-01 86 86 1.311E+01 1.200E+01 4.000E+02 6.4228E+00 1.9916E-01 1.2792E+00 87 87 2.054E+01 1.200E+01 4.000E+02 1.0063E+01 1.3216E-01 1.3299E+00 88 88 2.059E+01 1.200E+01 4.000E+02 1.0088E+01 1.4591E-01 1.4720E+00 89 89 2.889E+01 1.200E+01 4.000E+02 1.4157E+01 1.1743E-01 1.6625E+00 90 90 4.944E+01 1.200E+01 4.000E+02 2.4226E+01 1.5728E-01 3.8104E+00 91 91 5.021E+01 1.200E+01 4.000E+02 2.4604E+01 1.4900E-01 3.6661E+00 92 92 6.132E+01 1.200E+01 4.000E+02 3.0048E+01 1.5885E-01 4.7732E+00 93 93 7.230E+01 1.200E+01 4.000E+02 3.5428E+01 1.5596E-01 5.5253E+00 94 94 7.235E+01 1.200E+01 4.000E+02 3.5453E+01 1.5985E-01 5.6673E+00 95 95 8.296E+01 1.200E+01 4.000E+02 4.0648E+01 1.8769E-01 7.6292E+00 96 96 8.365E+01 1.200E+01 4.000E+02 4.0987E+01 1.7742E-01 7.2718E+00 97 97 9.388E+01 1.200E+01 4.000E+02 4.6002E+01 1.7910E-01 8.2391E+00 98 98 9.396E+01 1.200E+01 4.000E+02 4.6041E+01 1.8358E-01 8.4522E+00 99 99 1.031E+02 1.200E+01 4.000E+02 5.0499E+01 1.6970E-01 8.5695E+00 100 100 1.031E+02 1.200E+01 4.000E+02 5.0538E+01 1.7378E-01 8.7826E+00 101 101 1.182E+02 1.200E+01 4.000E+02 5.7895E+01 1.6081E-01 9.3102E+00 102 102 1.185E+02 1.200E+01 4.000E+02 5.8061E+01 1.7626E-01 1.0234E+01 103 103 1.242E+02 1.200E+01 4.000E+02 6.0869E+01 1.6670E-01 1.0147E+01 104 104 1.243E+02 1.200E+01 4.000E+02 6.0920E+01 1.7122E-01 1.0431E+01 105 105 1.326E+02 1.200E+01 4.000E+02 6.4951E+01 1.6025E-01 1.0408E+01 106 106 1.327E+02 1.200E+01 4.000E+02 6.5040E+01 1.6768E-01 1.0906E+01 107 107 3.074E-01 1.200E+01 4.000E+02 7.3787E-01 6.2988E-01 4.6477E-01 108 108 6.394E-01 1.200E+01 4.000E+02 1.5345E+00 1.6161E-01 2.4799E-01 109 109 9.849E-01 1.200E+01 4.000E+02 2.3638E+00 1.6444E-01 3.8870E-01 110 110 9.958E-01 1.200E+01 4.000E+02 2.3899E+00 2.8231E-01 6.7470E-01 111 111 2.024E+00 1.200E+01 4.000E+02 4.8582E+00 1.8162E-01 8.8232E-01 112 112 2.032E+00 1.200E+01 4.000E+02 4.8777E+00 2.2486E-01 1.0968E+00 113 113 3.752E+00 1.200E+01 4.000E+02 9.0046E+00 1.7612E-01 1.5859E+00 114 114 3.771E+00 1.200E+01 4.000E+02 9.0503E+00 2.3053E-01 2.0863E+00 115 115 5.860E+00 1.200E+01 4.000E+02 1.4065E+01 2.3887E-01 3.3597E+00 116 116 6.009E+00 1.200E+01 4.000E+02 1.4421E+01 1.9323E-01 2.7865E+00 117 117 7.070E+00 1.200E+01 4.000E+02 1.6968E+01 2.2702E-01 3.8522E+00 118 118 7.078E+00 1.200E+01 4.000E+02 1.6987E+01 2.3940E-01 4.0666E+00 119 119 8.142E+00 1.200E+01 4.000E+02 1.9540E+01 2.6631E-01 5.2038E+00 120 120 8.320E+00 1.200E+01 4.000E+02 1.9968E+01 2.7129E-01 5.4171E+00 121 121 9.340E+00 1.200E+01 4.000E+02 2.2417E+01 2.4135E-01 5.4103E+00 122 122 9.491E+00 1.200E+01 4.000E+02 2.2779E+01 2.1549E-01 4.9086E+00 123 123 1.038E+01 1.200E+01 4.000E+02 2.4905E+01 2.3419E-01 5.8324E+00 124 124 1.053E+01 1.200E+01 4.000E+02 2.5280E+01 2.1652E-01 5.4737E+00 125 125 1.264E+01 1.200E+01 4.000E+02 3.0347E+01 2.4118E-01 7.3190E+00 126 126 1.267E+01 1.200E+01 4.000E+02 3.0406E+01 2.6187E-01 7.9625E+00 127 127 1.486E+01 1.200E+01 4.000E+02 3.5666E+01 2.0880E-01 7.4472E+00 128 128 1.488E+01 1.200E+01 4.000E+02 3.5711E+01 2.2255E-01 7.9477E+00 129 129 4.138E-03 1.200E+01 4.000E+02 2.2758E-01 8.1435E-01 1.8533E-01 130 130 1.236E-02 1.200E+01 4.000E+02 6.7963E-01 8.8611E-01 6.0223E-01 131 131 3.293E-02 1.200E+01 4.000E+02 1.8113E+00 9.8683E-02 1.7874E-01 132 132 4.801E-02 1.200E+01 4.000E+02 2.6406E+00 1.7211E-01 4.5448E-01 133 133 6.961E-02 1.200E+01 4.000E+02 3.8284E+00 1.1742E-01 4.4953E-01 134 134 9.188E-02 1.200E+01 4.000E+02 5.0536E+00 1.4319E-01 7.2361E-01 135 135 1.234E-01 1.200E+01 4.000E+02 6.7869E+00 2.7009E-01 1.8331E+00 136 136 1.614E-01 1.200E+01 4.000E+02 8.8788E+00 2.9981E-01 2.6619E+00 137 137 2.057E-01 1.200E+01 4.000E+02 1.1311E+01 2.7147E-01 3.0706E+00 138 138 2.824E-01 1.200E+01 4.000E+02 1.5532E+01 3.2238E-01 5.0073E+00 139 139 3.612E-01 1.200E+01 4.000E+02 1.9865E+01 3.9170E-01 7.7810E+00 ------------------------------------------------------------------------------------- ETSI: Total elapsed time (after irradiation) before colonies are counted. TTP: Time available for repair before cells are plated. Total VC execution time (min): 18.569 VC 2.00I 15-JUL-2003 01-AUG-2003 05:08:32 PM