VC 2.00G 05-JUL-2003 23-JUL-2003 02:35:25 PM by RD Stewart (trebor@purdue.edu) PROGRAM FILE INPUT/OUTPUT AND RUN-TIME OPTIONS: ================================================================================ CMD: c:\vc\samples\bin\vc.exe c:\vc2\archive\hx118\rmr\hx118.inp FNI: C:\VC2\archive\hx118\rmr\hx118.inp FNO: C:\VC2\archive\hx118\rmr\hx118.out RADX: C:\VC2\archive\hx118\rmr\hx118.radx (66 exposures) -------------------------------------------------------------------------------- QECK TABLE: Cell and tissue kinetic parameters. ================================================================================ Duration of cell cycle (TCC): 10.00000 h Potential doubling time (Tpot): 480.00000 h (= 20.000 days) Cell birth rate (AX): 1.6636E+00 cell/day (= LOG(2)/TCC) Cell death rate (BX): 1.6289E+00 cell/day [=AX-LOG(2)/TPOT] Net cell birth rate (AX-BX): 3.4657E-02 cell/day Initial Number of Cells: non-dividing: 1.00000E+00 (100.000% = 1-GF) dividing: 0.00000E+00 ( 0.000% = GF) total: 1.00000E+00 (100.000% total) Life Support Capacity of System: Initial system capacity utilization: 0.000000% (=F0) Peak cell density (cells/cm^3): 1.00000E+38 (=KAP) Tissue volume (cm^3): 1.00000E+00 (=VOL) Maximum number of cells (cells): 1.00000E+38 (=KAP*VOL) -------------------------------------------------------------------------------- RMRM TABLE: Summary of RMR parameters and related (derived) quantities. ======================================================================== G0/G1 DNA CONTENT: 5667.000 Mbp/cell = 3.482938E+12 Da/cell ENDOGENOUS DAMAGE: per (h-Da) per (h-Mbp) per (h-cell) DSB = 0.00000E+00 0.00000E+00 0.00000E+00 DAMAGE FORMATION: per (Gy-Da) per (Gy-Mbp) per (Gy-cell) DSB = 7.17785E-12 4.41151E-03 25.000000 DAMAGE REPAIR/MISREPAIR: A0= 0.000000E+00 (=0.000%) (1-A0)*PHI= 1.257545E-02 (=1.258%) (1-A0)*(1-PHI)= 9.874246E-01 (=98.742%) RHT= 0.281958 h (=16.92 minute) LAM= 2.4583341E+00 (1/h) BMR= 1.2995176E-03 (1/h) LAM/BMR= 1.8917282E+03 GAM= 0.250 ***** EQUIVALENT LQ MODEL PARAMETERS ***** alpha = 0.314386 (1/Gy) beta = 0.039221 (1/Gy^2) alpha/beta = 8.015793 (Gy) ------------------------------------------------------------------------ NOTE: 1 bp = 614.6 Da (amu) = 1.0205E-09 pg DFAR TABLE: Cell survival as a function of dose and dose rate (FRDL=100.0%). ====================================================================================================== --- Duration (h) --- Dose Dose Rate ---- LETHAL DAMAGE PER CELL ---- SIM ID Exposure Sim (Gy) (Gy/h) Mutations Residual Total SF(dose) ------------------------------------------------------------------------------------------------------ 1 2.778E-13 9.600E+01 0.000E+00 0.000E+00 0.000E+00 0.000E+00 0.0000E+00 1.000000E+00 2 1.042E-01 2.410E+01 1.000E-01 9.600E-01 3.180E-02 2.771E-13 3.1799E-02 9.687012E-01 3 2.604E-01 2.426E+01 2.500E-01 9.600E-01 8.059E-02 1.661E-13 8.0595E-02 9.225674E-01 4 5.208E-01 2.452E+01 5.000E-01 9.600E-01 1.638E-01 6.343E-14 1.6385E-01 8.488710E-01 5 1.042E+00 2.504E+01 1.000E+00 9.600E-01 3.339E-01 1.059E-13 3.3387E-01 7.161482E-01 6 1.562E+00 2.556E+01 1.500E+00 9.600E-01 5.056E-01 0.000E+00 5.0558E-01 6.031548E-01 7 2.083E+00 2.608E+01 2.000E+00 9.600E-01 6.778E-01 1.222E-13 6.7776E-01 5.077536E-01 8 3.125E+00 2.712E+01 3.000E+00 9.600E-01 1.022E+00 1.152E-13 1.0224E+00 3.597292E-01 9 4.167E+00 2.817E+01 4.000E+00 9.600E-01 1.367E+00 1.146E-13 1.3671E+00 2.548436E-01 10 5.208E+00 2.921E+01 5.000E+00 9.600E-01 1.712E+00 1.145E-13 1.7118E+00 1.805385E-01 11 6.250E+00 3.025E+01 6.000E+00 9.600E-01 2.057E+00 1.145E-13 2.0565E+00 1.278987E-01 12 7.292E+00 3.129E+01 7.000E+00 9.600E-01 2.401E+00 1.145E-13 2.4012E+00 9.060705E-02 13 8.333E+00 3.233E+01 8.000E+00 9.600E-01 2.746E+00 1.145E-13 2.7459E+00 6.418862E-02 14 9.375E+00 3.338E+01 9.000E+00 9.600E-01 3.091E+00 1.145E-13 3.0906E+00 4.547305E-02 15 1.042E+01 3.442E+01 1.000E+01 9.600E-01 3.435E+00 1.145E-13 3.4353E+00 3.221440E-02 16 1.302E+01 3.702E+01 1.250E+01 9.600E-01 4.297E+00 1.145E-13 4.2971E+00 1.360787E-02 17 1.562E+01 3.962E+01 1.500E+01 9.600E-01 5.159E+00 1.145E-13 5.1589E+00 5.748178E-03 18 1.823E+01 4.223E+01 1.750E+01 9.600E-01 6.021E+00 1.145E-13 6.0206E+00 2.428121E-03 19 2.083E+01 4.483E+01 2.000E+01 9.600E-01 6.882E+00 1.145E-13 6.8824E+00 1.025676E-03 20 2.604E+01 5.004E+01 2.500E+01 9.600E-01 8.606E+00 1.145E-13 8.6059E+00 1.830166E-04 21 3.125E+01 5.525E+01 3.000E+01 9.600E-01 1.033E+01 1.145E-13 1.0329E+01 3.265657E-05 22 3.646E+01 6.046E+01 3.500E+01 9.600E-01 1.205E+01 1.145E-13 1.2053E+01 5.827077E-06 23 2.778E-13 9.600E+01 0.000E+00 0.000E+00 0.000E+00 0.000E+00 0.0000E+00 1.000000E+00 24 2.193E-02 2.402E+01 1.000E-01 4.560E+00 3.182E-02 4.063E-14 3.1824E-02 9.686775E-01 25 5.482E-02 2.405E+01 2.500E-01 4.560E+00 8.094E-02 2.955E-13 8.0936E-02 9.222524E-01 26 1.096E-01 2.411E+01 5.000E-01 4.560E+00 1.661E-01 0.000E+00 1.6614E-01 8.469311E-01 27 2.193E-01 2.422E+01 1.000E+00 4.560E+00 3.472E-01 0.000E+00 3.4715E-01 7.066983E-01 28 3.289E-01 2.433E+01 1.500E+00 4.560E+00 5.394E-01 0.000E+00 5.3938E-01 5.831080E-01 29 4.386E-01 2.444E+01 2.000E+00 4.560E+00 7.401E-01 1.619E-13 7.4007E-01 4.770811E-01 30 6.579E-01 2.466E+01 3.000E+00 4.560E+00 1.159E+00 0.000E+00 1.1590E+00 3.138023E-01 31 8.772E-01 2.488E+01 4.000E+00 4.560E+00 1.593E+00 1.874E-13 1.5927E+00 2.033768E-01 32 1.096E+00 2.510E+01 5.000E+00 4.560E+00 2.035E+00 5.973E-14 2.0348E+00 1.307069E-01 33 1.316E+00 2.532E+01 6.000E+00 4.560E+00 2.482E+00 0.000E+00 2.4817E+00 8.360311E-02 34 1.535E+00 2.554E+01 7.000E+00 4.560E+00 2.931E+00 4.400E-13 2.9313E+00 5.332952E-02 35 1.754E+00 2.575E+01 8.000E+00 4.560E+00 3.382E+00 3.629E-13 3.3824E+00 3.396589E-02 36 1.974E+00 2.597E+01 9.000E+00 4.560E+00 3.834E+00 1.484E-13 3.8344E+00 2.161413E-02 37 2.193E+00 2.619E+01 1.000E+01 4.560E+00 4.287E+00 2.331E-13 4.2869E+00 1.374725E-02 38 2.741E+00 2.674E+01 1.250E+01 4.560E+00 5.419E+00 2.050E-13 5.4192E+00 4.430807E-03 39 3.289E+00 2.729E+01 1.500E+01 4.560E+00 6.552E+00 5.275E-14 6.5519E+00 1.427365E-03 40 3.838E+00 2.784E+01 1.750E+01 4.560E+00 7.685E+00 6.879E-14 7.6848E+00 4.597637E-04 41 4.386E+00 2.839E+01 2.000E+01 4.560E+00 8.818E+00 5.854E-14 8.8177E+00 1.480887E-04 42 5.482E+00 2.948E+01 2.500E+01 4.560E+00 1.108E+01 5.582E-14 1.1084E+01 1.536346E-05 43 6.579E+00 3.058E+01 3.000E+01 4.560E+00 1.335E+01 2.674E-14 1.3349E+01 1.593877E-06 44 7.675E+00 3.168E+01 3.500E+01 4.560E+00 1.562E+01 3.015E-14 1.5615E+01 1.653563E-07 45 2.778E-13 9.600E+01 0.000E+00 0.000E+00 0.000E+00 0.000E+00 0.0000E+00 1.000000E+00 46 1.111E-03 2.400E+01 1.000E-01 9.000E+01 3.183E-02 1.159E-13 3.1830E-02 9.686711E-01 47 2.778E-03 2.400E+01 2.500E-01 9.000E+01 8.104E-02 2.692E-13 8.1037E-02 9.221597E-01 48 5.556E-03 2.401E+01 5.000E-01 9.000E+01 1.669E-01 7.196E-14 1.6691E-01 8.462748E-01 49 1.111E-02 2.401E+01 1.000E+00 9.000E+01 3.529E-01 1.218E-13 3.5291E-01 7.026371E-01 50 1.667E-02 2.402E+01 1.500E+00 9.000E+01 5.575E-01 1.484E-13 5.5751E-01 5.726348E-01 51 2.222E-02 2.402E+01 2.000E+00 9.000E+01 7.802E-01 1.959E-13 7.8020E-01 4.583148E-01 52 3.333E-02 2.403E+01 3.000E+00 9.000E+01 1.278E+00 0.000E+00 1.2780E+00 2.785949E-01 53 4.444E-02 2.404E+01 4.000E+00 9.000E+01 1.843E+00 3.544E-13 1.8427E+00 1.583937E-01 54 5.556E-02 2.406E+01 5.000E+00 9.000E+01 2.471E+00 0.000E+00 2.4708E+00 8.451758E-02 55 6.667E-02 2.407E+01 6.000E+00 9.000E+01 3.159E+00 1.092E-13 3.1591E+00 4.246258E-02 56 7.778E-02 2.408E+01 7.000E+00 9.000E+01 3.905E+00 6.189E-14 3.9046E+00 2.014851E-02 57 8.889E-02 2.409E+01 8.000E+00 9.000E+01 4.704E+00 3.590E-13 4.7044E+00 9.055456E-03 58 1.000E-01 2.410E+01 9.000E+00 9.000E+01 5.556E+00 4.947E-13 5.5557E+00 3.865394E-03 59 1.111E-01 2.411E+01 1.000E+01 9.000E+01 6.456E+00 1.042E-13 6.4560E+00 1.571136E-03 60 1.389E-01 2.414E+01 1.250E+01 9.000E+01 8.905E+00 3.159E-13 8.9051E+00 1.356920E-04 61 1.667E-01 2.417E+01 1.500E+01 9.000E+01 1.161E+01 9.858E-14 1.1611E+01 9.068722E-06 62 1.944E-01 2.419E+01 1.750E+01 9.000E+01 1.454E+01 4.408E-13 1.4542E+01 4.834559E-07 63 2.222E-01 2.422E+01 2.000E+01 9.000E+01 1.767E+01 4.160E-13 1.7673E+01 2.111102E-08 64 2.778E-01 2.428E+01 2.500E+01 9.000E+01 2.444E+01 5.206E-13 2.4444E+01 2.421118E-11 65 3.333E-01 2.433E+01 3.000E+01 9.000E+01 3.177E+01 1.601E-13 3.1769E+01 1.596083E-14 66 3.889E-01 2.439E+01 3.500E+01 9.000E+01 3.953E+01 4.134E-13 3.9527E+01 6.816319E-18 ------------------------------------------------------------------------------------------------------ NOTE: SF=EXP{-(lethal residual damage + lethal mutations)}. QECK TABLE: Cell survival, corrected for repopulation effects, as a function of dose and dose rate. Cell kinetic parameters are: N(0)=F0*KAP*VOL=1.00000E+00, TCC=10.0000 h, Tpot=20.000 days. ===================================================================================================================== TSIM DOSE DOSE RATE - SURVIVING FRACTION - --------- EXPECTED NUMBER OF CELLS ----------- SIM ID (day) (Gy) (Gy/h) no repop repop N(t)/N(0) N(0)*S(D) N(t)*S(D) NSC(t) --------------------------------------------------------------------------------------------------------------------- 1 4.000E+00 0.000E+00 0.000E+00 1.0000E+00 1.0000E+00 1.0000E+00 1.0000E+00 1.0000E+00 1.0000E+00 2 1.004E+00 1.000E-01 9.600E-01 9.6870E-01 9.6870E-01 1.0000E+00 9.6870E-01 9.6870E-01 9.6870E-01 3 1.011E+00 2.500E-01 9.600E-01 9.2257E-01 9.2257E-01 1.0000E+00 9.2257E-01 9.2257E-01 9.2257E-01 4 1.022E+00 5.000E-01 9.600E-01 8.4887E-01 8.4887E-01 1.0000E+00 8.4887E-01 8.4887E-01 8.4887E-01 5 1.043E+00 1.000E+00 9.600E-01 7.1615E-01 7.1615E-01 1.0000E+00 7.1615E-01 7.1615E-01 7.1615E-01 6 1.065E+00 1.500E+00 9.600E-01 6.0315E-01 6.0315E-01 1.0000E+00 6.0315E-01 6.0315E-01 6.0315E-01 7 1.087E+00 2.000E+00 9.600E-01 5.0775E-01 5.0775E-01 1.0000E+00 5.0775E-01 5.0775E-01 5.0775E-01 8 1.130E+00 3.000E+00 9.600E-01 3.5973E-01 3.5973E-01 1.0000E+00 3.5973E-01 3.5973E-01 3.5973E-01 9 1.174E+00 4.000E+00 9.600E-01 2.5484E-01 2.5484E-01 1.0000E+00 2.5484E-01 2.5484E-01 2.5484E-01 10 1.217E+00 5.000E+00 9.600E-01 1.8054E-01 1.8054E-01 1.0000E+00 1.8054E-01 1.8054E-01 1.8054E-01 11 1.260E+00 6.000E+00 9.600E-01 1.2790E-01 1.2790E-01 1.0000E+00 1.2790E-01 1.2790E-01 1.2790E-01 12 1.304E+00 7.000E+00 9.600E-01 9.0607E-02 9.0607E-02 1.0000E+00 9.0607E-02 9.0607E-02 9.0607E-02 13 1.347E+00 8.000E+00 9.600E-01 6.4189E-02 6.4189E-02 1.0000E+00 6.4189E-02 6.4189E-02 6.4189E-02 14 1.391E+00 9.000E+00 9.600E-01 4.5473E-02 4.5473E-02 1.0000E+00 4.5473E-02 4.5473E-02 4.5473E-02 15 1.434E+00 1.000E+01 9.600E-01 3.2214E-02 3.2214E-02 1.0000E+00 3.2214E-02 3.2214E-02 3.2214E-02 16 1.543E+00 1.250E+01 9.600E-01 1.3608E-02 1.3608E-02 1.0000E+00 1.3608E-02 1.3608E-02 1.3608E-02 17 1.651E+00 1.500E+01 9.600E-01 5.7482E-03 5.7482E-03 1.0000E+00 5.7482E-03 5.7482E-03 5.7482E-03 18 1.760E+00 1.750E+01 9.600E-01 2.4281E-03 2.4281E-03 1.0000E+00 2.4281E-03 2.4281E-03 2.4281E-03 19 1.868E+00 2.000E+01 9.600E-01 1.0257E-03 1.0257E-03 1.0000E+00 1.0257E-03 1.0257E-03 1.0257E-03 20 2.085E+00 2.500E+01 9.600E-01 1.8302E-04 1.8302E-04 1.0000E+00 1.8302E-04 1.8302E-04 1.8302E-04 21 2.302E+00 3.000E+01 9.600E-01 3.2657E-05 3.2657E-05 1.0000E+00 3.2657E-05 3.2657E-05 3.2657E-05 22 2.519E+00 3.500E+01 9.600E-01 5.8271E-06 5.8271E-06 1.0000E+00 5.8271E-06 5.8271E-06 5.8271E-06 23 4.000E+00 0.000E+00 0.000E+00 1.0000E+00 1.0000E+00 1.0000E+00 1.0000E+00 1.0000E+00 1.0000E+00 24 1.001E+00 1.000E-01 4.560E+00 9.6868E-01 9.6868E-01 1.0000E+00 9.6868E-01 9.6868E-01 9.6868E-01 25 1.002E+00 2.500E-01 4.560E+00 9.2225E-01 9.2225E-01 1.0000E+00 9.2225E-01 9.2225E-01 9.2225E-01 26 1.005E+00 5.000E-01 4.560E+00 8.4693E-01 8.4693E-01 1.0000E+00 8.4693E-01 8.4693E-01 8.4693E-01 27 1.009E+00 1.000E+00 4.560E+00 7.0670E-01 7.0670E-01 1.0000E+00 7.0670E-01 7.0670E-01 7.0670E-01 28 1.014E+00 1.500E+00 4.560E+00 5.8311E-01 5.8311E-01 1.0000E+00 5.8311E-01 5.8311E-01 5.8311E-01 29 1.018E+00 2.000E+00 4.560E+00 4.7708E-01 4.7708E-01 1.0000E+00 4.7708E-01 4.7708E-01 4.7708E-01 30 1.027E+00 3.000E+00 4.560E+00 3.1380E-01 3.1380E-01 1.0000E+00 3.1380E-01 3.1380E-01 3.1380E-01 31 1.037E+00 4.000E+00 4.560E+00 2.0338E-01 2.0338E-01 1.0000E+00 2.0338E-01 2.0338E-01 2.0338E-01 32 1.046E+00 5.000E+00 4.560E+00 1.3071E-01 1.3071E-01 1.0000E+00 1.3071E-01 1.3071E-01 1.3071E-01 33 1.055E+00 6.000E+00 4.560E+00 8.3603E-02 8.3603E-02 1.0000E+00 8.3603E-02 8.3603E-02 8.3603E-02 34 1.064E+00 7.000E+00 4.560E+00 5.3330E-02 5.3330E-02 1.0000E+00 5.3330E-02 5.3330E-02 5.3330E-02 35 1.073E+00 8.000E+00 4.560E+00 3.3966E-02 3.3966E-02 1.0000E+00 3.3966E-02 3.3966E-02 3.3966E-02 36 1.082E+00 9.000E+00 4.560E+00 2.1614E-02 2.1614E-02 1.0000E+00 2.1614E-02 2.1614E-02 2.1614E-02 37 1.091E+00 1.000E+01 4.560E+00 1.3747E-02 1.3747E-02 1.0000E+00 1.3747E-02 1.3747E-02 1.3747E-02 38 1.114E+00 1.250E+01 4.560E+00 4.4308E-03 4.4308E-03 1.0000E+00 4.4308E-03 4.4308E-03 4.4308E-03 39 1.137E+00 1.500E+01 4.560E+00 1.4274E-03 1.4274E-03 1.0000E+00 1.4274E-03 1.4274E-03 1.4274E-03 40 1.160E+00 1.750E+01 4.560E+00 4.5976E-04 4.5976E-04 1.0000E+00 4.5976E-04 4.5976E-04 4.5976E-04 41 1.183E+00 2.000E+01 4.560E+00 1.4809E-04 1.4809E-04 1.0000E+00 1.4809E-04 1.4809E-04 1.4809E-04 42 1.228E+00 2.500E+01 4.560E+00 1.5363E-05 1.5363E-05 1.0000E+00 1.5363E-05 1.5363E-05 1.5363E-05 43 1.274E+00 3.000E+01 4.560E+00 1.5939E-06 1.5939E-06 1.0000E+00 1.5939E-06 1.5939E-06 1.5939E-06 44 1.320E+00 3.500E+01 4.560E+00 1.6536E-07 1.6536E-07 1.0000E+00 1.6536E-07 1.6536E-07 1.6536E-07 45 4.000E+00 0.000E+00 0.000E+00 1.0000E+00 1.0000E+00 1.0000E+00 1.0000E+00 1.0000E+00 1.0000E+00 46 1.000E+00 1.000E-01 9.000E+01 9.6867E-01 9.6867E-01 1.0000E+00 9.6867E-01 9.6867E-01 9.6867E-01 47 1.000E+00 2.500E-01 9.000E+01 9.2216E-01 9.2216E-01 1.0000E+00 9.2216E-01 9.2216E-01 9.2216E-01 48 1.000E+00 5.000E-01 9.000E+01 8.4627E-01 8.4627E-01 1.0000E+00 8.4627E-01 8.4627E-01 8.4627E-01 49 1.000E+00 1.000E+00 9.000E+01 7.0264E-01 7.0264E-01 1.0000E+00 7.0264E-01 7.0264E-01 7.0264E-01 50 1.001E+00 1.500E+00 9.000E+01 5.7263E-01 5.7263E-01 1.0000E+00 5.7263E-01 5.7263E-01 5.7263E-01 51 1.001E+00 2.000E+00 9.000E+01 4.5831E-01 4.5831E-01 1.0000E+00 4.5831E-01 4.5831E-01 4.5831E-01 52 1.001E+00 3.000E+00 9.000E+01 2.7859E-01 2.7859E-01 1.0000E+00 2.7859E-01 2.7859E-01 2.7859E-01 53 1.002E+00 4.000E+00 9.000E+01 1.5839E-01 1.5839E-01 1.0000E+00 1.5839E-01 1.5839E-01 1.5839E-01 54 1.002E+00 5.000E+00 9.000E+01 8.4518E-02 8.4518E-02 1.0000E+00 8.4518E-02 8.4518E-02 8.4518E-02 55 1.003E+00 6.000E+00 9.000E+01 4.2463E-02 4.2463E-02 1.0000E+00 4.2463E-02 4.2463E-02 4.2463E-02 56 1.003E+00 7.000E+00 9.000E+01 2.0149E-02 2.0149E-02 1.0000E+00 2.0149E-02 2.0149E-02 2.0149E-02 57 1.004E+00 8.000E+00 9.000E+01 9.0555E-03 9.0555E-03 1.0000E+00 9.0555E-03 9.0555E-03 9.0555E-03 58 1.004E+00 9.000E+00 9.000E+01 3.8654E-03 3.8654E-03 1.0000E+00 3.8654E-03 3.8654E-03 3.8654E-03 59 1.005E+00 1.000E+01 9.000E+01 1.5711E-03 1.5711E-03 1.0000E+00 1.5711E-03 1.5711E-03 1.5711E-03 60 1.006E+00 1.250E+01 9.000E+01 1.3569E-04 1.3569E-04 1.0000E+00 1.3569E-04 1.3569E-04 1.3569E-04 61 1.007E+00 1.500E+01 9.000E+01 9.0687E-06 9.0687E-06 1.0000E+00 9.0687E-06 9.0687E-06 9.0687E-06 62 1.008E+00 1.750E+01 9.000E+01 4.8346E-07 4.8346E-07 1.0000E+00 4.8346E-07 4.8346E-07 4.8346E-07 63 1.009E+00 2.000E+01 9.000E+01 2.1111E-08 2.1111E-08 1.0000E+00 2.1111E-08 2.1111E-08 2.1111E-08 64 1.012E+00 2.500E+01 9.000E+01 2.4211E-11 2.4211E-11 1.0000E+00 2.4211E-11 2.4211E-11 2.4211E-11 65 1.014E+00 3.000E+01 9.000E+01 1.5961E-14 1.5961E-14 1.0000E+00 1.5961E-14 1.5961E-14 1.5961E-14 66 1.016E+00 3.500E+01 9.000E+01 6.8163E-18 6.8163E-18 1.0000E+00 6.8163E-18 6.8163E-18 6.8163E-18 --------------------------------------------------------------------------------------------------------------------- NOTE: N(0) is the initial number of cells (time=0 day), N(t) is the expected number of unirradiated (control) cells at TSIM, i.e., N(t)=N(0)*EXP[LN(2)*TSIM/TPOT]. The surviving fraction S(D) is the expected number of cells, per irradiated cell, that has not sustained lethal DNA damage (no corrections for repopulation effects). NSC(t) is the expected number of cells that survive irradiation, including repopulation effects (recommended method). The product N(t)*S(D) is an alternate method of estimating the surviving fraction with repopulation effects. DFAR TABLE: Mutagenesis and the induction of enhanced genetic instability (GI). Key GI model parameters are: (1-FRDL)=0.0%, NCM=1, NCG=1, and NCG*PGH*PGA=4.250E-06. ====================================================================================================== Dose Dose Rate -- NON-LETHAL MUTATIONS PER CELL -- **** PROBABILITY PER CELL **** SIM ID (Gy) (Gy/h) Mutations Residual Total AGF EGI EGI/SF ------------------------------------------------------------------------------------------------------ 1 0.000E+00 0.000E+00 0.000E+00 0.00E+00 0.00000E+00 0.000E+00 0.000E+00 0.000E+00 2 1.000E-01 9.600E-01 2.468E+00 0.00E+00 2.46820E+00 1.016E-05 1.016E-05 1.049E-05 3 2.500E-01 9.600E-01 6.169E+00 0.00E+00 6.16941E+00 2.419E-05 2.419E-05 2.622E-05 4 5.000E-01 9.600E-01 1.234E+01 0.00E+00 1.23362E+01 4.450E-05 4.450E-05 5.243E-05 5 1.000E+00 9.600E-01 2.467E+01 0.00E+00 2.46661E+01 7.507E-05 7.507E-05 1.048E-04 6 1.500E+00 9.600E-01 3.699E+01 0.00E+00 3.69944E+01 9.482E-05 9.482E-05 1.572E-04 7 2.000E+00 9.600E-01 4.932E+01 0.00E+00 4.93222E+01 1.064E-04 1.064E-04 2.096E-04 8 3.000E+00 9.600E-01 7.398E+01 0.00E+00 7.39776E+01 1.131E-04 1.131E-04 3.144E-04 9 4.000E+00 9.600E-01 9.863E+01 0.00E+00 9.86329E+01 1.068E-04 1.068E-04 4.191E-04 10 5.000E+00 9.600E-01 1.233E+02 0.00E+00 1.23288E+02 9.457E-05 9.457E-05 5.238E-04 11 6.000E+00 9.600E-01 1.479E+02 0.00E+00 1.47943E+02 8.039E-05 8.039E-05 6.286E-04 12 7.000E+00 9.600E-01 1.726E+02 0.00E+00 1.72599E+02 6.644E-05 6.644E-05 7.333E-04 13 8.000E+00 9.600E-01 1.973E+02 0.00E+00 1.97254E+02 5.379E-05 5.379E-05 8.380E-04 14 9.000E+00 9.600E-01 2.219E+02 0.00E+00 2.21909E+02 4.287E-05 4.287E-05 9.427E-04 15 1.000E+01 9.600E-01 2.466E+02 0.00E+00 2.46565E+02 3.374E-05 3.374E-05 1.047E-03 16 1.250E+01 9.600E-01 3.082E+02 0.00E+00 3.08203E+02 1.781E-05 1.781E-05 1.309E-03 17 1.500E+01 9.600E-01 3.698E+02 0.00E+00 3.69841E+02 9.028E-06 9.028E-06 1.571E-03 18 1.750E+01 9.600E-01 4.315E+02 0.00E+00 4.31479E+02 4.449E-06 4.449E-06 1.832E-03 19 2.000E+01 9.600E-01 4.931E+02 0.00E+00 4.93118E+02 2.147E-06 2.147E-06 2.094E-03 20 2.500E+01 9.600E-01 6.164E+02 0.00E+00 6.16394E+02 4.788E-07 4.788E-07 2.616E-03 21 3.000E+01 9.600E-01 7.397E+02 0.00E+00 7.39671E+02 1.025E-07 1.025E-07 3.139E-03 22 3.500E+01 9.600E-01 8.629E+02 0.00E+00 8.62947E+02 2.133E-08 2.133E-08 3.661E-03 23 0.000E+00 0.000E+00 0.000E+00 0.00E+00 0.00000E+00 0.000E+00 0.000E+00 0.000E+00 24 1.000E-01 4.560E+00 2.468E+00 0.00E+00 2.46818E+00 1.016E-05 1.016E-05 1.049E-05 25 2.500E-01 4.560E+00 6.169E+00 0.00E+00 6.16906E+00 2.418E-05 2.418E-05 2.622E-05 26 5.000E-01 4.560E+00 1.233E+01 0.00E+00 1.23339E+01 4.439E-05 4.439E-05 5.242E-05 27 1.000E+00 4.560E+00 2.465E+01 0.00E+00 2.46528E+01 7.404E-05 7.404E-05 1.048E-04 28 1.500E+00 4.560E+00 3.696E+01 0.00E+00 3.69606E+01 9.159E-05 9.159E-05 1.571E-04 29 2.000E+00 4.560E+00 4.926E+01 0.00E+00 4.92599E+01 9.987E-05 9.987E-05 2.093E-04 30 3.000E+00 4.560E+00 7.384E+01 0.00E+00 7.38410E+01 9.846E-05 9.846E-05 3.138E-04 31 4.000E+00 4.560E+00 9.841E+01 0.00E+00 9.84073E+01 8.504E-05 8.504E-05 4.181E-04 32 5.000E+00 4.560E+00 1.230E+02 0.00E+00 1.22965E+02 6.829E-05 6.829E-05 5.225E-04 33 6.000E+00 4.560E+00 1.475E+02 0.00E+00 1.47518E+02 5.240E-05 5.240E-05 6.268E-04 34 7.000E+00 4.560E+00 1.721E+02 0.00E+00 1.72069E+02 3.899E-05 3.899E-05 7.310E-04 35 8.000E+00 4.560E+00 1.966E+02 0.00E+00 1.96618E+02 2.837E-05 2.837E-05 8.353E-04 36 9.000E+00 4.560E+00 2.212E+02 0.00E+00 2.21166E+02 2.031E-05 2.031E-05 9.395E-04 37 1.000E+01 4.560E+00 2.457E+02 0.00E+00 2.45713E+02 1.435E-05 1.435E-05 1.044E-03 38 1.250E+01 4.560E+00 3.071E+02 0.00E+00 3.07081E+02 5.779E-06 5.779E-06 1.304E-03 39 1.500E+01 4.560E+00 3.684E+02 0.00E+00 3.68448E+02 2.233E-06 2.233E-06 1.565E-03 40 1.750E+01 4.560E+00 4.298E+02 0.00E+00 4.29815E+02 8.391E-07 8.391E-07 1.825E-03 41 2.000E+01 4.560E+00 4.912E+02 0.00E+00 4.91182E+02 3.088E-07 3.088E-07 2.085E-03 42 2.500E+01 4.560E+00 6.139E+02 0.00E+00 6.13916E+02 4.003E-08 4.003E-08 2.606E-03 43 3.000E+01 4.560E+00 7.367E+02 0.00E+00 7.36651E+02 4.982E-09 4.982E-09 3.126E-03 44 3.500E+01 4.560E+00 8.594E+02 0.00E+00 8.59385E+02 6.028E-10 6.028E-10 3.646E-03 45 0.000E+00 0.000E+00 0.000E+00 0.00E+00 0.00000E+00 0.000E+00 0.000E+00 0.000E+00 46 1.000E-01 9.000E+01 2.468E+00 0.00E+00 2.46817E+00 1.016E-05 1.016E-05 1.049E-05 47 2.500E-01 9.000E+01 6.169E+00 0.00E+00 6.16896E+00 2.418E-05 2.418E-05 2.622E-05 48 5.000E-01 9.000E+01 1.233E+01 0.00E+00 1.23331E+01 4.436E-05 4.436E-05 5.241E-05 49 1.000E+00 9.000E+01 2.465E+01 0.00E+00 2.46471E+01 7.360E-05 7.360E-05 1.047E-04 50 1.500E+00 9.000E+01 3.694E+01 0.00E+00 3.69425E+01 8.990E-05 8.990E-05 1.570E-04 51 2.000E+00 9.000E+01 4.922E+01 0.00E+00 4.92198E+01 9.586E-05 9.586E-05 2.092E-04 52 3.000E+00 9.000E+01 7.372E+01 0.00E+00 7.37220E+01 8.728E-05 8.728E-05 3.133E-04 53 4.000E+00 9.000E+01 9.816E+01 0.00E+00 9.81573E+01 6.606E-05 6.606E-05 4.171E-04 54 5.000E+00 9.000E+01 1.225E+02 0.00E+00 1.22529E+02 4.400E-05 4.400E-05 5.206E-04 55 6.000E+00 9.000E+01 1.468E+02 0.00E+00 1.46841E+02 2.649E-05 2.649E-05 6.239E-04 56 7.000E+00 9.000E+01 1.711E+02 0.00E+00 1.71095E+02 1.465E-05 1.465E-05 7.269E-04 57 8.000E+00 9.000E+01 1.953E+02 0.00E+00 1.95296E+02 7.513E-06 7.513E-06 8.297E-04 58 9.000E+00 9.000E+01 2.194E+02 0.00E+00 2.19444E+02 3.603E-06 3.603E-06 9.322E-04 59 1.000E+01 9.000E+01 2.435E+02 0.00E+00 2.43544E+02 1.625E-06 1.625E-06 1.035E-03 60 1.250E+01 9.000E+01 3.036E+02 0.00E+00 3.03595E+02 1.750E-07 1.750E-07 1.289E-03 61 1.500E+01 9.000E+01 3.634E+02 0.00E+00 3.63389E+02 1.399E-08 1.399E-08 1.543E-03 62 1.750E+01 9.000E+01 4.230E+02 0.00E+00 4.22958E+02 8.683E-10 8.683E-10 1.796E-03 63 2.000E+01 9.000E+01 4.823E+02 0.00E+00 4.82327E+02 4.323E-11 4.323E-11 2.048E-03 64 2.500E+01 9.000E+01 6.006E+02 0.00E+00 6.00556E+02 6.172E-14 6.172E-14 2.549E-03 65 3.000E+01 9.000E+01 7.182E+02 0.00E+00 7.18231E+02 4.865E-17 4.865E-17 3.048E-03 66 3.500E+01 9.000E+01 8.355E+02 0.00E+00 8.35473E+02 2.416E-20 2.416E-20 3.544E-03 ------------------------------------------------------------------------------------------------------ AGF: function or expression of at least 1 of the 1 critical gene targets is altered. EGI: altered gene function or expression causes enhanced genetic instability. NEOM TABLE: Neoplastic transformation as a function of dose and dose rate at t=42.000 days. Parameters: TFS=1.1500E-05 (1/wk), TFU=2.0000E-03 (1/wk), NCM=1, NCG=1, and NCG*PGH*PGA=4.3E-06. ====================================================================================================== Dose Dose Rate Non-Lethal Genetic Instability *** TRANSFORMATION FREQUENCY *** SIM ID (Gy) (Gy/h) Mutations EGI EGI/SF BKG TPS TPI ------------------------------------------------------------------------------------------------------ 1 0.000E+00 0.000E+00 0.000E+00 0.000E+00 0.000E+00 6.8995E-05 6.8995E-05 6.8995E-05 2 1.000E-01 9.600E-01 2.468E+00 1.016E-05 1.049E-05 6.8994E-05 6.9120E-05 6.6956E-05 3 2.500E-01 9.600E-01 6.169E+00 2.419E-05 2.622E-05 6.8993E-05 6.9306E-05 6.3940E-05 4 5.000E-01 9.600E-01 1.234E+01 4.450E-05 5.243E-05 6.8992E-05 6.9617E-05 5.9096E-05 5 1.000E+00 9.600E-01 2.467E+01 7.507E-05 1.048E-04 6.8988E-05 7.0238E-05 5.0301E-05 6 1.500E+00 9.600E-01 3.699E+01 9.482E-05 1.572E-04 6.8984E-05 7.0860E-05 4.2739E-05 7 2.000E+00 9.600E-01 4.932E+01 1.064E-04 2.096E-04 6.8981E-05 7.1481E-05 3.6295E-05 8 3.000E+00 9.600E-01 7.398E+01 1.131E-04 3.144E-04 6.8974E-05 7.2723E-05 2.6161E-05 9 4.000E+00 9.600E-01 9.863E+01 1.068E-04 4.191E-04 6.8966E-05 7.3965E-05 1.8850E-05 10 5.000E+00 9.600E-01 1.233E+02 9.457E-05 5.238E-04 6.8959E-05 7.5208E-05 1.3578E-05 11 6.000E+00 9.600E-01 1.479E+02 8.039E-05 6.286E-04 6.8952E-05 7.6450E-05 9.7778E-06 12 7.000E+00 9.600E-01 1.726E+02 6.644E-05 7.333E-04 6.8945E-05 7.7691E-05 7.0394E-06 13 8.000E+00 9.600E-01 1.973E+02 5.379E-05 8.380E-04 6.8937E-05 7.8933E-05 5.0666E-06 14 9.000E+00 9.600E-01 2.219E+02 4.287E-05 9.427E-04 6.8930E-05 8.0175E-05 3.6458E-06 15 1.000E+01 9.600E-01 2.466E+02 3.374E-05 1.047E-03 6.8923E-05 8.1416E-05 2.6228E-06 16 1.250E+01 9.600E-01 3.082E+02 1.781E-05 1.309E-03 6.8905E-05 8.4519E-05 1.1501E-06 17 1.500E+01 9.600E-01 3.698E+02 9.028E-06 1.571E-03 6.8887E-05 8.7621E-05 5.0366E-07 18 1.750E+01 9.600E-01 4.315E+02 4.449E-06 1.832E-03 6.8869E-05 9.0723E-05 2.2029E-07 19 2.000E+01 9.600E-01 4.931E+02 2.147E-06 2.094E-03 6.8851E-05 9.3823E-05 9.6232E-08 20 2.500E+01 9.600E-01 6.164E+02 4.788E-07 2.616E-03 6.8815E-05 1.0002E-04 1.8306E-08 21 3.000E+01 9.600E-01 7.397E+02 1.025E-07 3.139E-03 6.8779E-05 1.0622E-04 3.4687E-09 22 3.500E+01 9.600E-01 8.629E+02 2.133E-08 3.661E-03 6.8743E-05 1.1241E-04 6.5502E-10 23 0.000E+00 0.000E+00 0.000E+00 0.000E+00 0.000E+00 6.8995E-05 6.8995E-05 6.8995E-05 24 1.000E-01 4.560E+00 2.468E+00 1.016E-05 1.049E-05 6.8994E-05 6.9120E-05 6.6955E-05 25 2.500E-01 4.560E+00 6.169E+00 2.418E-05 2.622E-05 6.8993E-05 6.9306E-05 6.3918E-05 26 5.000E-01 4.560E+00 1.233E+01 4.439E-05 5.242E-05 6.8992E-05 6.9617E-05 5.8961E-05 27 1.000E+00 4.560E+00 2.465E+01 7.404E-05 1.048E-04 6.8988E-05 7.0238E-05 4.9637E-05 28 1.500E+00 4.560E+00 3.696E+01 9.159E-05 1.571E-04 6.8984E-05 7.0858E-05 4.1318E-05 29 2.000E+00 4.560E+00 4.926E+01 9.987E-05 2.093E-04 6.8981E-05 7.1478E-05 3.4101E-05 30 3.000E+00 4.560E+00 7.384E+01 9.846E-05 3.138E-04 6.8974E-05 7.2716E-05 2.2819E-05 31 4.000E+00 4.560E+00 9.841E+01 8.504E-05 4.181E-04 6.8966E-05 7.3954E-05 1.5041E-05 32 5.000E+00 4.560E+00 1.230E+02 6.829E-05 5.225E-04 6.8959E-05 7.5191E-05 9.8280E-06 33 6.000E+00 4.560E+00 1.475E+02 5.240E-05 6.268E-04 6.8952E-05 7.6428E-05 6.3896E-06 34 7.000E+00 4.560E+00 1.721E+02 3.899E-05 7.310E-04 6.8945E-05 7.7665E-05 4.1418E-06 35 8.000E+00 4.560E+00 1.966E+02 2.837E-05 8.353E-04 6.8938E-05 7.8901E-05 2.6799E-06 36 9.000E+00 4.560E+00 2.212E+02 2.031E-05 9.395E-04 6.8930E-05 8.0137E-05 1.7321E-06 37 1.000E+01 4.560E+00 2.457E+02 1.435E-05 1.044E-03 6.8923E-05 8.1373E-05 1.1187E-06 38 1.250E+01 4.560E+00 3.071E+02 5.779E-06 1.304E-03 6.8905E-05 8.4463E-05 3.7424E-07 39 1.500E+01 4.560E+00 3.684E+02 2.233E-06 1.565E-03 6.8887E-05 8.7551E-05 1.2497E-07 40 1.750E+01 4.560E+00 4.298E+02 8.391E-07 1.825E-03 6.8869E-05 9.0639E-05 4.1673E-08 41 2.000E+01 4.560E+00 4.912E+02 3.088E-07 2.085E-03 6.8851E-05 9.3726E-05 1.3880E-08 42 2.500E+01 4.560E+00 6.139E+02 4.003E-08 2.606E-03 6.8815E-05 9.9898E-05 1.5348E-09 43 3.000E+01 4.560E+00 7.367E+02 4.982E-09 3.126E-03 6.8780E-05 1.0607E-04 1.6906E-10 44 3.500E+01 4.560E+00 8.594E+02 6.028E-10 3.646E-03 6.8744E-05 1.1223E-04 1.8558E-11 45 0.000E+00 0.000E+00 0.000E+00 0.000E+00 0.000E+00 6.8995E-05 6.8995E-05 6.8995E-05 46 1.000E-01 9.000E+01 2.468E+00 1.016E-05 1.049E-05 6.8994E-05 6.9120E-05 6.6954E-05 47 2.500E-01 9.000E+01 6.169E+00 2.418E-05 2.622E-05 6.8993E-05 6.9306E-05 6.3911E-05 48 5.000E-01 9.000E+01 1.233E+01 4.436E-05 5.241E-05 6.8992E-05 6.9617E-05 5.8915E-05 49 1.000E+00 9.000E+01 2.465E+01 7.360E-05 1.047E-04 6.8988E-05 7.0237E-05 4.9351E-05 50 1.500E+00 9.000E+01 3.694E+01 8.990E-05 1.570E-04 6.8984E-05 7.0857E-05 4.0575E-05 51 2.000E+00 9.000E+01 4.922E+01 9.586E-05 2.092E-04 6.8981E-05 7.1476E-05 3.2758E-05 52 3.000E+00 9.000E+01 7.372E+01 8.728E-05 3.133E-04 6.8974E-05 7.2710E-05 2.0257E-05 53 4.000E+00 9.000E+01 9.816E+01 6.606E-05 4.171E-04 6.8966E-05 7.3942E-05 1.1712E-05 54 5.000E+00 9.000E+01 1.225E+02 4.400E-05 5.206E-04 6.8959E-05 7.5169E-05 6.3531E-06 55 6.000E+00 9.000E+01 1.468E+02 2.649E-05 6.239E-04 6.8952E-05 7.6394E-05 3.2439E-06 56 7.000E+00 9.000E+01 1.711E+02 1.465E-05 7.269E-04 6.8945E-05 7.7616E-05 1.5638E-06 57 8.000E+00 9.000E+01 1.953E+02 7.513E-06 8.297E-04 6.8938E-05 7.8834E-05 7.1388E-07 58 9.000E+00 9.000E+01 2.194E+02 3.603E-06 9.322E-04 6.8931E-05 8.0050E-05 3.0943E-07 59 1.000E+01 9.000E+01 2.435E+02 1.625E-06 1.035E-03 6.8924E-05 8.1264E-05 1.2768E-07 60 1.250E+01 9.000E+01 3.036E+02 1.750E-07 1.289E-03 6.8906E-05 8.4287E-05 1.1437E-08 61 1.500E+01 9.000E+01 3.634E+02 1.399E-08 1.543E-03 6.8889E-05 8.7297E-05 7.9167E-10 62 1.750E+01 9.000E+01 4.230E+02 8.683E-10 1.796E-03 6.8871E-05 9.0294E-05 4.3653E-11 63 2.000E+01 9.000E+01 4.823E+02 4.323E-11 2.048E-03 6.8854E-05 9.3281E-05 1.9692E-12 64 2.500E+01 9.000E+01 6.006E+02 6.172E-14 2.549E-03 6.8819E-05 9.9226E-05 2.4024E-15 65 3.000E+01 9.000E+01 7.182E+02 4.865E-17 3.048E-03 6.8785E-05 1.0514E-04 1.6781E-18 66 3.500E+01 9.000E+01 8.355E+02 2.416E-20 3.544E-03 6.8751E-05 1.1103E-04 7.5682E-22 ------------------------------------------------------------------------------------------------------ TPS: Transformation frequency per survivor, TPI: Transformation frequency per irradiated cell EGI: Probabilty random mutational events caused enhanced genetic instability (EGI). BKG: Background (spontaneous) cell transformation frequency RMRM TABLE: LQ model dose protraction factor(s) and cell survival estimates (FRDL=100.0%). LQ model parameters are: alpha = 0.314 (1/Gy), alpha/beta = 8.016 (Gy) , lamda = 2.458E+00 (1/h). ====================================================================================================== --- Duration (h) --- Dose Dose Rate* ***** G FACTOR ***** ******* SF(dose) ******* SIM ID Exposure Sim (Gy) (Gy/h) GL GEFF SF1 SF2 ------------------------------------------------------------------------------------------------------ 1 2.778E-13 9.600E+01 0.000E+00 0.000E+00 0.000E+00 0.000E+00 1.0000E+00 1.000000E+00 2 1.042E-01 2.410E+01 1.000E-01 9.600E-01 9.198E-01 9.191E-01 9.6870E-01 9.687012E-01 3 2.604E-01 2.426E+01 2.500E-01 9.600E-01 8.168E-01 8.152E-01 9.2256E-01 9.225674E-01 4 5.208E-01 2.452E+01 5.000E-01 9.600E-01 6.811E-01 6.787E-01 8.4885E-01 8.488710E-01 5 1.042E+00 2.504E+01 1.000E+00 9.600E-01 4.996E-01 4.967E-01 7.1607E-01 7.161482E-01 6 1.562E+00 2.556E+01 1.500E+00 9.600E-01 3.880E-01 3.853E-01 6.0301E-01 6.031548E-01 7 2.083E+00 2.608E+01 2.000E+00 9.600E-01 3.147E-01 3.122E-01 5.0756E-01 5.077536E-01 8 3.125E+00 2.712E+01 3.000E+00 9.600E-01 2.265E-01 2.245E-01 3.5948E-01 3.597292E-01 9 4.167E+00 2.817E+01 4.000E+00 9.600E-01 1.762E-01 1.746E-01 2.5459E-01 2.548436E-01 10 5.208E+00 2.921E+01 5.000E+00 9.600E-01 1.440E-01 1.427E-01 1.8030E-01 1.805385E-01 11 6.250E+00 3.025E+01 6.000E+00 9.600E-01 1.217E-01 1.205E-01 1.2769E-01 1.278987E-01 12 7.292E+00 3.129E+01 7.000E+00 9.600E-01 1.053E-01 1.043E-01 9.0431E-02 9.060705E-02 13 8.333E+00 3.233E+01 8.000E+00 9.600E-01 9.286E-02 9.196E-02 6.4044E-02 6.418862E-02 14 9.375E+00 3.338E+01 9.000E+00 9.600E-01 8.301E-02 8.221E-02 4.5356E-02 4.547305E-02 15 1.042E+01 3.442E+01 1.000E+01 9.600E-01 7.505E-02 7.432E-02 3.2122E-02 3.221440E-02 16 1.302E+01 3.702E+01 1.250E+01 9.600E-01 6.053E-02 5.993E-02 1.3558E-02 1.360787E-02 17 1.562E+01 3.962E+01 1.500E+01 9.600E-01 5.071E-02 5.021E-02 5.7227E-03 5.748178E-03 18 1.823E+01 4.223E+01 1.750E+01 9.600E-01 4.363E-02 4.320E-02 2.4155E-03 2.428121E-03 19 2.083E+01 4.483E+01 2.000E+01 9.600E-01 3.829E-02 3.791E-02 1.0195E-03 1.025676E-03 20 2.604E+01 5.004E+01 2.500E+01 9.600E-01 3.075E-02 3.044E-02 1.8164E-04 1.830166E-04 21 3.125E+01 5.525E+01 3.000E+01 9.600E-01 2.570E-02 2.544E-02 3.2360E-05 3.265657E-05 22 3.646E+01 6.046E+01 3.500E+01 9.600E-01 2.207E-02 2.184E-02 5.7652E-06 5.827077E-06 23 2.778E-13 9.600E+01 0.000E+00 0.000E+00 0.000E+00 0.000E+00 1.0000E+00 1.000000E+00 24 2.193E-02 2.402E+01 1.000E-01 4.560E+00 9.823E-01 9.814E-01 9.6868E-01 9.686775E-01 25 5.482E-02 2.405E+01 2.500E-01 4.560E+00 9.565E-01 9.545E-01 9.2225E-01 9.222524E-01 26 1.096E-01 2.411E+01 5.000E-01 4.560E+00 9.159E-01 9.121E-01 8.4690E-01 8.469311E-01 27 2.193E-01 2.422E+01 1.000E+00 4.560E+00 8.421E-01 8.354E-01 7.0651E-01 7.066983E-01 28 3.289E-01 2.433E+01 1.500E+00 4.560E+00 7.772E-01 7.683E-01 5.8265E-01 5.831080E-01 29 4.386E-01 2.444E+01 2.000E+00 4.560E+00 7.198E-01 7.094E-01 4.7630E-01 4.770811E-01 30 6.579E-01 2.466E+01 3.000E+00 4.560E+00 6.237E-01 6.114E-01 3.1245E-01 3.138023E-01 31 8.772E-01 2.488E+01 4.000E+00 4.560E+00 5.471E-01 5.341E-01 2.0172E-01 2.033768E-01 32 1.096E+00 2.510E+01 5.000E+00 4.560E+00 4.853E-01 4.721E-01 1.2902E-01 1.307069E-01 33 1.316E+00 2.532E+01 6.000E+00 4.560E+00 4.347E-01 4.217E-01 8.2080E-02 8.360311E-02 34 1.535E+00 2.554E+01 7.000E+00 4.560E+00 3.928E-01 3.801E-01 5.2051E-02 5.332952E-02 35 1.754E+00 2.575E+01 8.000E+00 4.560E+00 3.576E-01 3.455E-01 3.2948E-02 3.396589E-02 36 1.974E+00 2.597E+01 9.000E+00 4.560E+00 3.279E-01 3.163E-01 2.0833E-02 2.161413E-02 37 2.193E+00 2.619E+01 1.000E+01 4.560E+00 3.025E-01 2.914E-01 1.3165E-02 1.374725E-02 38 2.741E+00 2.674E+01 1.250E+01 4.560E+00 2.528E-01 2.430E-01 4.1734E-03 4.430807E-03 39 3.289E+00 2.729E+01 1.500E+01 4.560E+00 2.167E-01 2.081E-01 1.3221E-03 1.427365E-03 40 3.838E+00 2.784E+01 1.750E+01 4.560E+00 1.895E-01 1.817E-01 4.1877E-04 4.597637E-04 41 4.386E+00 2.839E+01 2.000E+01 4.560E+00 1.683E-01 1.613E-01 1.3264E-04 1.480887E-04 42 5.482E+00 2.948E+01 2.500E+01 4.560E+00 1.374E-01 1.315E-01 1.3306E-05 1.536346E-05 43 6.579E+00 3.058E+01 3.000E+01 4.560E+00 1.160E-01 1.110E-01 1.3347E-06 1.593877E-06 44 7.675E+00 3.168E+01 3.500E+01 4.560E+00 1.004E-01 9.598E-02 1.3389E-07 1.653563E-07 45 2.778E-13 9.600E+01 0.000E+00 0.000E+00 0.000E+00 0.000E+00 1.0000E+00 1.000000E+00 46 1.111E-03 2.400E+01 1.000E-01 9.000E+01 9.991E-01 9.982E-01 9.6867E-01 9.686711E-01 47 2.778E-03 2.400E+01 2.500E-01 9.000E+01 9.977E-01 9.955E-01 9.2215E-01 9.221597E-01 48 5.556E-03 2.401E+01 5.000E-01 9.000E+01 9.955E-01 9.911E-01 8.4624E-01 8.462748E-01 49 1.111E-02 2.401E+01 1.000E+00 9.000E+01 9.910E-01 9.824E-01 7.0240E-01 7.026371E-01 50 1.667E-02 2.402E+01 1.500E+00 9.000E+01 9.865E-01 9.737E-01 5.7199E-01 5.726348E-01 51 2.222E-02 2.402E+01 2.000E+00 9.000E+01 9.820E-01 9.652E-01 4.5711E-01 4.583148E-01 52 3.333E-02 2.403E+01 3.000E+00 9.000E+01 9.732E-01 9.486E-01 2.7618E-01 2.785949E-01 53 4.444E-02 2.404E+01 4.000E+00 9.000E+01 9.646E-01 9.324E-01 1.5523E-01 1.583937E-01 54 5.556E-02 2.406E+01 5.000E+00 9.000E+01 9.560E-01 9.167E-01 8.1325E-02 8.451758E-02 55 6.667E-02 2.407E+01 6.000E+00 9.000E+01 9.475E-01 9.015E-01 3.9788E-02 4.246258E-02 56 7.778E-02 2.408E+01 7.000E+00 9.000E+01 9.392E-01 8.866E-01 1.8212E-02 2.014851E-02 57 8.889E-02 2.409E+01 8.000E+00 9.000E+01 9.310E-01 8.722E-01 7.8131E-03 9.055456E-03 58 1.000E-01 2.410E+01 9.000E+00 9.000E+01 9.229E-01 8.581E-01 3.1471E-03 3.865394E-03 59 1.111E-01 2.411E+01 1.000E+01 9.000E+01 9.148E-01 8.445E-01 1.1922E-03 1.571136E-03 60 1.389E-01 2.414E+01 1.250E+01 9.000E+01 8.953E-01 8.119E-01 8.1386E-05 1.356920E-04 61 1.667E-01 2.417E+01 1.500E+01 9.000E+01 8.763E-01 7.813E-01 3.9207E-06 9.068722E-06 62 1.944E-01 2.419E+01 1.750E+01 9.000E+01 8.580E-01 7.527E-01 1.3639E-07 4.834559E-07 63 2.222E-01 2.422E+01 2.000E+01 9.000E+01 8.403E-01 7.257E-01 3.5005E-09 2.111102E-08 64 2.778E-01 2.428E+01 2.500E+01 9.000E+01 8.065E-01 6.766E-01 1.0021E-12 2.421118E-11 65 3.333E-01 2.433E+01 3.000E+01 9.000E+01 7.748E-01 6.328E-01 1.0637E-16 1.596083E-14 66 3.889E-01 2.439E+01 3.500E+01 9.000E+01 7.450E-01 5.937E-01 4.7516E-21 6.816319E-18 ------------------------------------------------------------------------------------------------------ GL=[2*[x+exp(-x)-1]/(x*x), where x = {lamda}*{irradiation time} and GEFF=-(alpha+LOG(SF)/D)/(beta*D). In the formula for GEFF, SF is surviving fraction as computed using the RMR model. The effects of lethal residual damage are included in the GEFF dose protraction factor but not GL. The SF estimates are: SF1=EXP{-dose*[alpha+gl*beta*dose]} and SF2=EXP{-dose*(alpha+geff*beta*dose)}. QECK TABLE: Tumor control probability (TCP) estimates as a function of dose and dose rate. Cell kinetic parameters are: N(0)=F0*KAP*VOL=1.00000E+00, TCC=10.0000 h, Tpot=20.000 days. The *MAX* estimate is recommended (the other TCP estimates are mainly included in the table for diagnostic purposes). ===================================================================================================================== TSIM DOSE ---- EXPECTED NUMBER OF CELLS ---- ------ TUMOR CONTROL PROBABILITY (TCP) ------- SIM ID (day) (Gy) N(0)*S(D) N(t)*S(D) NSC(t) N(0)*S(D) N(t)*S(D) NSC(t) *MAX* --------------------------------------------------------------------------------------------------------------------- 1 4.000E+00 0.000E+00 1.0000E+00 1.0000E+00 1.0000E+00 3.6788E-01 3.6788E-01 3.6788E-01 3.6788E-01 2 1.004E+00 1.000E-01 9.6870E-01 9.6870E-01 9.6870E-01 3.7958E-01 3.7958E-01 3.7958E-01 3.7958E-01 3 1.011E+00 2.500E-01 9.2257E-01 9.2257E-01 9.2257E-01 3.9750E-01 3.9750E-01 3.9750E-01 3.9750E-01 4 1.022E+00 5.000E-01 8.4887E-01 8.4887E-01 8.4887E-01 4.2790E-01 4.2790E-01 4.2790E-01 4.2790E-01 5 1.043E+00 1.000E+00 7.1615E-01 7.1615E-01 7.1615E-01 4.8863E-01 4.8863E-01 4.8863E-01 4.8863E-01 6 1.065E+00 1.500E+00 6.0315E-01 6.0315E-01 6.0315E-01 5.4708E-01 5.4708E-01 5.4708E-01 5.4708E-01 7 1.087E+00 2.000E+00 5.0775E-01 5.0775E-01 5.0775E-01 6.0185E-01 6.0185E-01 6.0185E-01 6.0185E-01 8 1.130E+00 3.000E+00 3.5973E-01 3.5973E-01 3.5973E-01 6.9787E-01 6.9787E-01 6.9787E-01 6.9787E-01 9 1.174E+00 4.000E+00 2.5484E-01 2.5484E-01 2.5484E-01 7.7504E-01 7.7504E-01 7.7504E-01 7.7504E-01 10 1.217E+00 5.000E+00 1.8054E-01 1.8054E-01 1.8054E-01 8.3482E-01 8.3482E-01 8.3482E-01 8.3482E-01 11 1.260E+00 6.000E+00 1.2790E-01 1.2790E-01 1.2790E-01 8.7994E-01 8.7994E-01 8.7994E-01 8.7994E-01 12 1.304E+00 7.000E+00 9.0607E-02 9.0607E-02 9.0607E-02 9.1338E-01 9.1338E-01 9.1338E-01 9.1338E-01 13 1.347E+00 8.000E+00 6.4189E-02 6.4189E-02 6.4189E-02 9.3783E-01 9.3783E-01 9.3783E-01 9.3783E-01 14 1.391E+00 9.000E+00 4.5473E-02 4.5473E-02 4.5473E-02 9.5555E-01 9.5555E-01 9.5555E-01 9.5555E-01 15 1.434E+00 1.000E+01 3.2214E-02 3.2214E-02 3.2214E-02 9.6830E-01 9.6830E-01 9.6830E-01 9.6830E-01 16 1.543E+00 1.250E+01 1.3608E-02 1.3608E-02 1.3608E-02 9.8648E-01 9.8648E-01 9.8648E-01 9.8648E-01 17 1.651E+00 1.500E+01 5.7482E-03 5.7482E-03 5.7482E-03 9.9427E-01 9.9427E-01 9.9427E-01 9.9427E-01 18 1.760E+00 1.750E+01 2.4281E-03 2.4281E-03 2.4281E-03 9.9757E-01 9.9757E-01 9.9757E-01 9.9757E-01 19 1.868E+00 2.000E+01 1.0257E-03 1.0257E-03 1.0257E-03 9.9897E-01 9.9897E-01 9.9897E-01 9.9897E-01 20 2.085E+00 2.500E+01 1.8302E-04 1.8302E-04 1.8302E-04 9.9982E-01 9.9982E-01 9.9982E-01 9.9982E-01 21 2.302E+00 3.000E+01 3.2657E-05 3.2657E-05 3.2657E-05 9.9997E-01 9.9997E-01 9.9997E-01 9.9997E-01 22 2.519E+00 3.500E+01 5.8271E-06 5.8271E-06 5.8271E-06 9.9999E-01 9.9999E-01 9.9999E-01 9.9999E-01 23 4.000E+00 0.000E+00 1.0000E+00 1.0000E+00 1.0000E+00 3.6788E-01 3.6788E-01 3.6788E-01 3.6788E-01 24 1.001E+00 1.000E-01 9.6868E-01 9.6868E-01 9.6868E-01 3.7958E-01 3.7958E-01 3.7958E-01 3.7958E-01 25 1.002E+00 2.500E-01 9.2225E-01 9.2225E-01 9.2225E-01 3.9762E-01 3.9762E-01 3.9762E-01 3.9762E-01 26 1.005E+00 5.000E-01 8.4693E-01 8.4693E-01 8.4693E-01 4.2873E-01 4.2873E-01 4.2873E-01 4.2873E-01 27 1.009E+00 1.000E+00 7.0670E-01 7.0670E-01 7.0670E-01 4.9327E-01 4.9327E-01 4.9327E-01 4.9327E-01 28 1.014E+00 1.500E+00 5.8311E-01 5.8311E-01 5.8311E-01 5.5816E-01 5.5816E-01 5.5816E-01 5.5816E-01 29 1.018E+00 2.000E+00 4.7708E-01 4.7708E-01 4.7708E-01 6.2059E-01 6.2059E-01 6.2059E-01 6.2059E-01 30 1.027E+00 3.000E+00 3.1380E-01 3.1380E-01 3.1380E-01 7.3066E-01 7.3066E-01 7.3066E-01 7.3066E-01 31 1.037E+00 4.000E+00 2.0338E-01 2.0338E-01 2.0338E-01 8.1597E-01 8.1597E-01 8.1597E-01 8.1597E-01 32 1.046E+00 5.000E+00 1.3071E-01 1.3071E-01 1.3071E-01 8.7747E-01 8.7747E-01 8.7747E-01 8.7747E-01 33 1.055E+00 6.000E+00 8.3603E-02 8.3603E-02 8.3603E-02 9.1980E-01 9.1980E-01 9.1980E-01 9.1980E-01 34 1.064E+00 7.000E+00 5.3330E-02 5.3330E-02 5.3330E-02 9.4807E-01 9.4807E-01 9.4807E-01 9.4807E-01 35 1.073E+00 8.000E+00 3.3966E-02 3.3966E-02 3.3966E-02 9.6660E-01 9.6660E-01 9.6660E-01 9.6660E-01 36 1.082E+00 9.000E+00 2.1614E-02 2.1614E-02 2.1614E-02 9.7862E-01 9.7862E-01 9.7862E-01 9.7862E-01 37 1.091E+00 1.000E+01 1.3747E-02 1.3747E-02 1.3747E-02 9.8635E-01 9.8635E-01 9.8635E-01 9.8635E-01 38 1.114E+00 1.250E+01 4.4308E-03 4.4308E-03 4.4308E-03 9.9558E-01 9.9558E-01 9.9558E-01 9.9558E-01 39 1.137E+00 1.500E+01 1.4274E-03 1.4274E-03 1.4274E-03 9.9857E-01 9.9857E-01 9.9857E-01 9.9857E-01 40 1.160E+00 1.750E+01 4.5976E-04 4.5976E-04 4.5976E-04 9.9954E-01 9.9954E-01 9.9954E-01 9.9954E-01 41 1.183E+00 2.000E+01 1.4809E-04 1.4809E-04 1.4809E-04 9.9985E-01 9.9985E-01 9.9985E-01 9.9985E-01 42 1.228E+00 2.500E+01 1.5363E-05 1.5363E-05 1.5363E-05 9.9998E-01 9.9998E-01 9.9998E-01 9.9998E-01 43 1.274E+00 3.000E+01 1.5939E-06 1.5939E-06 1.5939E-06 1.0000E+00 1.0000E+00 1.0000E+00 1.0000E+00 44 1.320E+00 3.500E+01 1.6536E-07 1.6536E-07 1.6536E-07 1.0000E+00 1.0000E+00 1.0000E+00 1.0000E+00 45 4.000E+00 0.000E+00 1.0000E+00 1.0000E+00 1.0000E+00 3.6788E-01 3.6788E-01 3.6788E-01 3.6788E-01 46 1.000E+00 1.000E-01 9.6867E-01 9.6867E-01 9.6867E-01 3.7959E-01 3.7959E-01 3.7959E-01 3.7959E-01 47 1.000E+00 2.500E-01 9.2216E-01 9.2216E-01 9.2216E-01 3.9766E-01 3.9766E-01 3.9766E-01 3.9766E-01 48 1.000E+00 5.000E-01 8.4627E-01 8.4627E-01 8.4627E-01 4.2901E-01 4.2901E-01 4.2901E-01 4.2901E-01 49 1.000E+00 1.000E+00 7.0264E-01 7.0264E-01 7.0264E-01 4.9528E-01 4.9528E-01 4.9528E-01 4.9528E-01 50 1.001E+00 1.500E+00 5.7263E-01 5.7263E-01 5.7263E-01 5.6404E-01 5.6404E-01 5.6404E-01 5.6404E-01 51 1.001E+00 2.000E+00 4.5831E-01 4.5831E-01 4.5831E-01 6.3235E-01 6.3235E-01 6.3235E-01 6.3235E-01 52 1.001E+00 3.000E+00 2.7859E-01 2.7859E-01 2.7859E-01 7.5685E-01 7.5685E-01 7.5685E-01 7.5685E-01 53 1.002E+00 4.000E+00 1.5839E-01 1.5839E-01 1.5839E-01 8.5351E-01 8.5351E-01 8.5351E-01 8.5351E-01 54 1.002E+00 5.000E+00 8.4518E-02 8.4518E-02 8.4518E-02 9.1896E-01 9.1896E-01 9.1896E-01 9.1896E-01 55 1.003E+00 6.000E+00 4.2463E-02 4.2463E-02 4.2463E-02 9.5843E-01 9.5843E-01 9.5843E-01 9.5843E-01 56 1.003E+00 7.000E+00 2.0149E-02 2.0149E-02 2.0149E-02 9.8005E-01 9.8005E-01 9.8005E-01 9.8005E-01 57 1.004E+00 8.000E+00 9.0555E-03 9.0555E-03 9.0555E-03 9.9099E-01 9.9099E-01 9.9099E-01 9.9099E-01 58 1.004E+00 9.000E+00 3.8654E-03 3.8654E-03 3.8654E-03 9.9614E-01 9.9614E-01 9.9614E-01 9.9614E-01 59 1.005E+00 1.000E+01 1.5711E-03 1.5711E-03 1.5711E-03 9.9843E-01 9.9843E-01 9.9843E-01 9.9843E-01 60 1.006E+00 1.250E+01 1.3569E-04 1.3569E-04 1.3569E-04 9.9986E-01 9.9986E-01 9.9986E-01 9.9986E-01 61 1.007E+00 1.500E+01 9.0687E-06 9.0687E-06 9.0687E-06 9.9999E-01 9.9999E-01 9.9999E-01 9.9999E-01 62 1.008E+00 1.750E+01 4.8346E-07 4.8346E-07 4.8346E-07 1.0000E+00 1.0000E+00 1.0000E+00 1.0000E+00 63 1.009E+00 2.000E+01 2.1111E-08 2.1111E-08 2.1111E-08 1.0000E+00 1.0000E+00 1.0000E+00 1.0000E+00 64 1.012E+00 2.500E+01 2.4211E-11 2.4211E-11 2.4211E-11 1.0000E+00 1.0000E+00 1.0000E+00 1.0000E+00 65 1.014E+00 3.000E+01 1.5961E-14 1.5961E-14 1.5961E-14 1.0000E+00 1.0000E+00 1.0000E+00 1.0000E+00 66 1.016E+00 3.500E+01 6.8163E-18 6.8163E-18 6.8163E-18 1.0000E+00 1.0000E+00 1.0000E+00 1.0000E+00 --------------------------------------------------------------------------------------------------------------------- NOTE: TCP={probability no cells survive}=EXP{-(expected number of surviving cells)}. TCP estimates are based on the expected number of surviving cells with and without corrections for repopulation effects. The *MAX* TCP is the peak (all time points after irradiation) estimate derived from NSC(t). RADX EXPOSURE SUMMARY ============================================================================== SCENARIO ----- DURATION ----- ------ DOSE (Gy) ----- -- DOSE RATE (Gy/h) -- NUMBER hours days Background Total Background Total* ------------------------------------------------------------------------------ 1 2.778E-13 1.157E-14 0.0000E+00 0.0000E+00 0.0000E+00 0.0000E+00 2 1.042E-01 4.340E-03 0.0000E+00 1.0000E-01 0.0000E+00 9.6000E-01 3 2.604E-01 1.085E-02 0.0000E+00 2.5000E-01 0.0000E+00 9.6000E-01 4 5.208E-01 2.170E-02 0.0000E+00 5.0000E-01 0.0000E+00 9.6000E-01 5 1.042E+00 4.340E-02 0.0000E+00 1.0000E+00 0.0000E+00 9.6000E-01 6 1.562E+00 6.510E-02 0.0000E+00 1.5000E+00 0.0000E+00 9.6000E-01 7 2.083E+00 8.681E-02 0.0000E+00 2.0000E+00 0.0000E+00 9.6000E-01 8 3.125E+00 1.302E-01 0.0000E+00 3.0000E+00 0.0000E+00 9.6000E-01 9 4.167E+00 1.736E-01 0.0000E+00 4.0000E+00 0.0000E+00 9.6000E-01 10 5.208E+00 2.170E-01 0.0000E+00 5.0000E+00 0.0000E+00 9.6000E-01 11 6.250E+00 2.604E-01 0.0000E+00 6.0000E+00 0.0000E+00 9.6000E-01 12 7.292E+00 3.038E-01 0.0000E+00 7.0000E+00 0.0000E+00 9.6000E-01 13 8.333E+00 3.472E-01 0.0000E+00 8.0000E+00 0.0000E+00 9.6000E-01 14 9.375E+00 3.906E-01 0.0000E+00 9.0000E+00 0.0000E+00 9.6000E-01 15 1.042E+01 4.340E-01 0.0000E+00 1.0000E+01 0.0000E+00 9.6000E-01 16 1.302E+01 5.425E-01 0.0000E+00 1.2500E+01 0.0000E+00 9.6000E-01 17 1.562E+01 6.510E-01 0.0000E+00 1.5000E+01 0.0000E+00 9.6000E-01 18 1.823E+01 7.595E-01 0.0000E+00 1.7500E+01 0.0000E+00 9.6000E-01 19 2.083E+01 8.681E-01 0.0000E+00 2.0000E+01 0.0000E+00 9.6000E-01 20 2.604E+01 1.085E+00 0.0000E+00 2.5000E+01 0.0000E+00 9.6000E-01 21 3.125E+01 1.302E+00 0.0000E+00 3.0000E+01 0.0000E+00 9.6000E-01 22 3.646E+01 1.519E+00 0.0000E+00 3.5000E+01 0.0000E+00 9.6000E-01 23 2.778E-13 1.157E-14 0.0000E+00 0.0000E+00 0.0000E+00 0.0000E+00 24 2.193E-02 9.137E-04 0.0000E+00 1.0000E-01 0.0000E+00 4.5600E+00 25 5.482E-02 2.284E-03 0.0000E+00 2.5000E-01 0.0000E+00 4.5600E+00 26 1.096E-01 4.569E-03 0.0000E+00 5.0000E-01 0.0000E+00 4.5600E+00 27 2.193E-01 9.137E-03 0.0000E+00 1.0000E+00 0.0000E+00 4.5600E+00 28 3.289E-01 1.371E-02 0.0000E+00 1.5000E+00 0.0000E+00 4.5600E+00 29 4.386E-01 1.827E-02 0.0000E+00 2.0000E+00 0.0000E+00 4.5600E+00 30 6.579E-01 2.741E-02 0.0000E+00 3.0000E+00 0.0000E+00 4.5600E+00 31 8.772E-01 3.655E-02 0.0000E+00 4.0000E+00 0.0000E+00 4.5600E+00 32 1.096E+00 4.569E-02 0.0000E+00 5.0000E+00 0.0000E+00 4.5600E+00 33 1.316E+00 5.482E-02 0.0000E+00 6.0000E+00 0.0000E+00 4.5600E+00 34 1.535E+00 6.396E-02 0.0000E+00 7.0000E+00 0.0000E+00 4.5600E+00 35 1.754E+00 7.310E-02 0.0000E+00 8.0000E+00 0.0000E+00 4.5600E+00 36 1.974E+00 8.224E-02 0.0000E+00 9.0000E+00 0.0000E+00 4.5600E+00 37 2.193E+00 9.137E-02 0.0000E+00 1.0000E+01 0.0000E+00 4.5600E+00 38 2.741E+00 1.142E-01 0.0000E+00 1.2500E+01 0.0000E+00 4.5600E+00 39 3.289E+00 1.371E-01 0.0000E+00 1.5000E+01 0.0000E+00 4.5600E+00 40 3.838E+00 1.599E-01 0.0000E+00 1.7500E+01 0.0000E+00 4.5600E+00 41 4.386E+00 1.827E-01 0.0000E+00 2.0000E+01 0.0000E+00 4.5600E+00 42 5.482E+00 2.284E-01 0.0000E+00 2.5000E+01 0.0000E+00 4.5600E+00 43 6.579E+00 2.741E-01 0.0000E+00 3.0000E+01 0.0000E+00 4.5600E+00 44 7.675E+00 3.198E-01 0.0000E+00 3.5000E+01 0.0000E+00 4.5600E+00 45 2.778E-13 1.157E-14 0.0000E+00 0.0000E+00 0.0000E+00 0.0000E+00 46 1.111E-03 4.630E-05 0.0000E+00 1.0000E-01 0.0000E+00 9.0000E+01 47 2.778E-03 1.157E-04 0.0000E+00 2.5000E-01 0.0000E+00 9.0000E+01 48 5.556E-03 2.315E-04 0.0000E+00 5.0000E-01 0.0000E+00 9.0000E+01 49 1.111E-02 4.630E-04 0.0000E+00 1.0000E+00 0.0000E+00 9.0000E+01 50 1.667E-02 6.944E-04 0.0000E+00 1.5000E+00 0.0000E+00 9.0000E+01 51 2.222E-02 9.259E-04 0.0000E+00 2.0000E+00 0.0000E+00 9.0000E+01 52 3.333E-02 1.389E-03 0.0000E+00 3.0000E+00 0.0000E+00 9.0000E+01 53 4.444E-02 1.852E-03 0.0000E+00 4.0000E+00 0.0000E+00 9.0000E+01 54 5.556E-02 2.315E-03 0.0000E+00 5.0000E+00 0.0000E+00 9.0000E+01 55 6.667E-02 2.778E-03 0.0000E+00 6.0000E+00 0.0000E+00 9.0000E+01 56 7.778E-02 3.241E-03 0.0000E+00 7.0000E+00 0.0000E+00 9.0000E+01 57 8.889E-02 3.704E-03 0.0000E+00 8.0000E+00 0.0000E+00 9.0000E+01 58 1.000E-01 4.167E-03 0.0000E+00 9.0000E+00 0.0000E+00 9.0000E+01 59 1.111E-01 4.630E-03 0.0000E+00 1.0000E+01 0.0000E+00 9.0000E+01 60 1.389E-01 5.787E-03 0.0000E+00 1.2500E+01 0.0000E+00 9.0000E+01 61 1.667E-01 6.944E-03 0.0000E+00 1.5000E+01 0.0000E+00 9.0000E+01 62 1.944E-01 8.102E-03 0.0000E+00 1.7500E+01 0.0000E+00 9.0000E+01 63 2.222E-01 9.259E-03 0.0000E+00 2.0000E+01 0.0000E+00 9.0000E+01 64 2.778E-01 1.157E-02 0.0000E+00 2.5000E+01 0.0000E+00 9.0000E+01 65 3.333E-01 1.389E-02 0.0000E+00 3.0000E+01 0.0000E+00 9.0000E+01 66 3.889E-01 1.620E-02 0.0000E+00 3.5000E+01 0.0000E+00 9.0000E+01 ------------------------------------------------------------------------------ * Dose rate is the delivered dose divided by the duration of the exposure scenario. Total VC execution time (min): 7.55000E-03 VC 2.00G 05-JUL-2003 23-JUL-2003 02:35:25 PM