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Calibrated Input File (RMR)
PC-3 Prostate Carcinoma Cells

/*
 REFERENCE:
Leith JT, Quaranto L, Padfield G, Michelson S, and Hercbergs A. Radiobiological studies of PC-3 and DU-145 human prostate cancer cells: x-ray sensitivity in vitro and hypoxic fractions of xenografted tumors in vivo. International Journal of Radiation Oncology, Biology, and Physics. 25, 283-287 (1993)
 PREPARED BY: DAVID CARLSON (djcarlso@purdue.edu))
 DATE: 20-NOV-2003
*/
MODEL: DRM=RMR CKM=QECK !Model Specification CELL: DNA=5.667D+09 NC=46 IRAD: CL=40 !Radiation damage to DNA CLRP: RHT=6.0029257E+00 BMR=5.3465899E-05 PHI=9.6012346E-03 A0=0.00 CCKM: TCC=10 TPOT=20 GF=0.0 N0=1 KAP=1.0D+38 VOL=1 RBM: KX=6.0E+06 FMAX=1 !Analysis of PFGE data ! Parameters that impact on solution accuracy SOLVER: DBLV=0 ETOL=1.0E-09 MXSS=999999 HMAX=10 ! Parameters that control the time steps and stopping criteria SIMCON: FSDX=1 TSAX=12 TCUT=96 FRDL=1.0E+00 RCUT=1.0D-09 !IRRADIATION CONDITIONS (single fraction) RADX: ADR=RX1 AD=RX2 RX1 = 60 / !dose rate (Gy/h) RX2 = 0 0.1 0.25 0.5 1 1.5 2 3 4 5 6 7 8 9 10 12.5 15 17.5 20 25 30 35 /

 


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