VC 2.00G 05-JUL-2003 20-JUL-2003 04:00:03 PM by RD Stewart (trebor@purdue.edu) PROGRAM FILE INPUT/OUTPUT AND RUN-TIME OPTIONS: ================================================================================ CMD: c:\vc\samples\bin\vc.exe c:\vc2\archive\ag1522\tlk\ag1522.inp FNI: C:\VC2\archive\ag1522\tlk\ag1522.inp FNO: C:\VC2\archive\ag1522\tlk\ag1522.out RADX: C:\VC2\archive\ag1522\tlk\ag1522.radx (88 exposures) -------------------------------------------------------------------------------- QECK TABLE: Cell and tissue kinetic parameters. ================================================================================ Duration of cell cycle (TCC): 10.00000 h Potential doubling time (Tpot): 480.00000 h (= 20.000 days) Cell birth rate (AX): 1.6636E+00 cell/day (= LOG(2)/TCC) Cell death rate (BX): 1.6289E+00 cell/day [=AX-LOG(2)/TPOT] Net cell birth rate (AX-BX): 3.4657E-02 cell/day Initial Number of Cells: non-dividing: 1.00000E+00 (100.000% = 1-GF) dividing: 0.00000E+00 ( 0.000% = GF) total: 1.00000E+00 (100.000% total) Life Support Capacity of System: Initial system capacity utilization: 0.000000% (=F0) Peak cell density (cells/cm^3): 1.00000E+38 (=KAP) Tissue volume (cm^3): 1.00000E+00 (=VOL) Maximum number of cells (cells): 1.00000E+38 (=KAP*VOL) -------------------------------------------------------------------------------- TLKM TABLE: Summary of TLK parameters and related (derived) quantities. ======================================================================== G0/G1 DNA CONTENT: 5667.000 Mbp/cell = 3.482938E+12 Da/cell ENDOGENOUS DAMAGE: per (h-Da) per (h-Mbp) per (h-cell) Simple DSB = 0.00000E+00 0.00000E+00 0.00000E+00 Complex DSB = 0.00000E+00 0.00000E+00 0.00000E+00 Total DSB = 0.00000E+00 0.00000E+00 0.00000E+00 DAMAGE FORMATION: per (Gy-Da) per (Gy-Mbp) per (Gy-cell) Simple DSB = 5.74228E-12 3.52920E-03 20.000000 Complex DSB = 1.43557E-12 8.82301E-04 5.000000 Total DSB = 7.17785E-12 4.41151E-03 25.000000 DAMAGE REPAIR/MISREPAIR: A1= 7.500000E-01 (=75.000%) A2= 2.500000E-01 (=25.000%) PHI1= 2.142980E-02 (=2.143%) PHI2= 2.142980E-02 (=2.143%) (1-A1)*PHI1= 5.357450E-03 (=0.536%) (1-A2)*PHI2= 1.607235E-02 (=1.607%) (1-A1)*(1-PHI1)= 2.446426E-01 (=24.464%) (1-A2)*(1-PHI2)= 7.339277E-01 (=73.393%) RHT1= 0.861792 h (=51.71 minute) RHT2= 0.877353 h (=52.64 minute) LAM1= 8.0430875E-01 (1/h) LAM2= 7.9004336E-01 (1/h) BMR= 4.3976503E-04 (1/h) LAM1/BMR= 1.8289511E+03 LAM2/BMR= 1.7965125E+03 (LAM1+LAM2)/BMR= 3.6254636E+03 GAM= 0.250 ************** EQUIVALENT LQ MODEL PARAMETERS ************************** Simple Complex Total alpha: 1.0715E-01 + 8.0362E-02 = 1.8751074E-01 (1/Gy) beta: 3.3352E-02 + 8.2278E-03 = 4.1580124E-02 (1/Gy^2) alpha/beta: 4.5096244 (Gy) ------------------------------------------------------------------------ NOTE: 1 bp = 614.6 Da (amu) = 1.0205E-09 pg DFAR TABLE: Cell survival as a function of dose and dose rate (FRDL=100.0%). ====================================================================================================== --- Duration (h) --- Dose Dose Rate ---- LETHAL DAMAGE PER CELL ---- SIM ID Exposure Sim (Gy) (Gy/h) Mutations Residual Total SF(dose) ------------------------------------------------------------------------------------------------------ 1 2.778E-13 9.600E+01 0.000E+00 0.000E+00 0.000E+00 0.000E+00 0.0000E+00 1.000000E+00 2 4.167E-01 3.642E+01 1.000E-01 2.400E-01 1.912E-02 4.017E-11 1.9124E-02 9.810578E-01 3 1.042E+00 4.904E+01 2.500E-01 2.400E-01 4.888E-02 4.871E-12 4.8878E-02 9.522972E-01 4 2.083E+00 5.008E+01 5.000E-01 2.400E-01 1.001E-01 0.000E+00 1.0013E-01 9.047183E-01 5 4.167E+00 5.217E+01 1.000E+00 2.400E-01 2.051E-01 0.000E+00 2.0513E-01 8.145435E-01 6 6.250E+00 5.425E+01 1.500E+00 2.400E-01 3.110E-01 0.000E+00 3.1103E-01 7.326941E-01 7 8.333E+00 5.633E+01 2.000E+00 2.400E-01 4.171E-01 0.000E+00 4.1709E-01 6.589588E-01 8 1.250E+01 6.050E+01 3.000E+00 2.400E-01 6.293E-01 0.000E+00 6.2930E-01 5.329663E-01 9 1.667E+01 6.467E+01 4.000E+00 2.400E-01 8.415E-01 0.000E+00 8.4151E-01 4.310600E-01 10 2.083E+01 6.883E+01 5.000E+00 2.400E-01 1.054E+00 0.000E+00 1.0537E+00 3.486386E-01 11 2.500E+01 7.300E+01 6.000E+00 2.400E-01 1.266E+00 0.000E+00 1.2659E+00 2.819767E-01 12 2.917E+01 7.717E+01 7.000E+00 2.400E-01 1.478E+00 0.000E+00 1.4781E+00 2.280610E-01 13 3.333E+01 8.133E+01 8.000E+00 2.400E-01 1.690E+00 0.000E+00 1.6904E+00 1.844544E-01 14 3.750E+01 8.550E+01 9.000E+00 2.400E-01 1.903E+00 0.000E+00 1.9026E+00 1.491855E-01 15 4.167E+01 8.967E+01 1.000E+01 2.400E-01 2.115E+00 0.000E+00 2.1148E+00 1.206603E-01 16 5.208E+01 1.001E+02 1.250E+01 2.400E-01 2.645E+00 0.000E+00 2.6453E+00 7.098377E-02 17 6.250E+01 1.105E+02 1.500E+01 2.400E-01 3.176E+00 0.000E+00 3.1758E+00 4.175933E-02 18 7.292E+01 1.209E+02 1.750E+01 2.400E-01 3.706E+00 0.000E+00 3.7064E+00 2.456677E-02 19 8.333E+01 1.313E+02 2.000E+01 2.400E-01 4.237E+00 0.000E+00 4.2369E+00 1.445249E-02 20 1.042E+02 1.522E+02 2.500E+01 2.400E-01 5.298E+00 0.000E+00 5.2979E+00 5.001861E-03 21 1.250E+02 1.730E+02 3.000E+01 2.400E-01 6.359E+00 0.000E+00 6.3590E+00 1.731094E-03 22 1.458E+02 1.938E+02 3.500E+01 2.400E-01 7.420E+00 0.000E+00 7.4201E+00 5.991143E-04 23 2.778E-13 9.600E+01 0.000E+00 0.000E+00 0.000E+00 0.000E+00 0.0000E+00 1.000000E+00 24 2.941E-01 3.629E+01 1.000E-01 3.400E-01 1.914E-02 4.670E-11 1.9136E-02 9.810462E-01 25 7.353E-01 4.874E+01 2.500E-01 3.400E-01 4.903E-02 5.967E-12 4.9029E-02 9.521539E-01 26 1.471E+00 4.947E+01 5.000E-01 3.400E-01 1.010E-01 0.000E+00 1.0101E-01 9.039272E-01 27 2.941E+00 5.094E+01 1.000E+00 3.400E-01 2.091E-01 0.000E+00 2.0911E-01 8.113083E-01 28 4.412E+00 5.241E+01 1.500E+00 3.400E-01 3.194E-01 0.000E+00 3.1936E-01 7.266131E-01 29 5.882E+00 5.388E+01 2.000E+00 3.400E-01 4.303E-01 0.000E+00 4.3027E-01 6.503343E-01 30 8.824E+00 5.682E+01 3.000E+00 3.400E-01 6.525E-01 0.000E+00 6.5254E-01 5.207208E-01 31 1.176E+01 5.976E+01 4.000E+00 3.400E-01 8.749E-01 0.000E+00 8.7492E-01 4.168969E-01 32 1.471E+01 6.271E+01 5.000E+00 3.400E-01 1.097E+00 0.000E+00 1.0973E+00 3.337708E-01 33 1.765E+01 6.565E+01 6.000E+00 3.400E-01 1.320E+00 0.000E+00 1.3197E+00 2.672192E-01 34 2.059E+01 6.859E+01 7.000E+00 3.400E-01 1.542E+00 0.000E+00 1.5421E+00 2.139375E-01 35 2.353E+01 7.153E+01 8.000E+00 3.400E-01 1.764E+00 0.000E+00 1.7645E+00 1.712798E-01 36 2.647E+01 7.447E+01 9.000E+00 3.400E-01 1.987E+00 0.000E+00 1.9868E+00 1.371278E-01 37 2.941E+01 7.741E+01 1.000E+01 3.400E-01 2.209E+00 0.000E+00 2.2092E+00 1.097855E-01 38 3.676E+01 8.476E+01 1.250E+01 3.400E-01 2.765E+00 0.000E+00 2.7652E+00 6.296410E-02 39 4.412E+01 9.212E+01 1.500E+01 3.400E-01 3.321E+00 0.000E+00 3.3212E+00 3.611114E-02 40 5.147E+01 9.947E+01 1.750E+01 3.400E-01 3.877E+00 0.000E+00 3.8771E+00 2.071044E-02 41 5.882E+01 1.068E+02 2.000E+01 3.400E-01 4.433E+00 0.000E+00 4.4331E+00 1.187784E-02 42 7.353E+01 1.215E+02 2.500E+01 3.400E-01 5.545E+00 0.000E+00 5.5450E+00 3.906914E-03 43 8.824E+01 1.362E+02 3.000E+01 3.400E-01 6.657E+00 0.000E+00 6.6569E+00 1.285080E-03 44 1.029E+02 1.509E+02 3.500E+01 3.400E-01 7.769E+00 0.000E+00 7.7689E+00 4.226945E-04 45 2.778E-13 9.600E+01 0.000E+00 0.000E+00 0.000E+00 0.000E+00 0.0000E+00 1.000000E+00 46 1.408E-01 3.614E+01 1.000E-01 7.100E-01 1.915E-02 5.165E-12 1.9151E-02 9.810309E-01 47 3.521E-01 4.835E+01 2.500E-01 7.100E-01 4.924E-02 0.000E+00 4.9243E-02 9.519496E-01 48 7.042E-01 4.870E+01 5.000E-01 7.100E-01 1.024E-01 0.000E+00 1.0241E-01 9.026628E-01 49 1.408E+00 4.941E+01 1.000E+00 7.100E-01 2.168E-01 0.000E+00 2.1680E-01 8.050882E-01 50 2.113E+00 5.011E+01 1.500E+00 7.100E-01 3.379E-01 0.000E+00 3.3793E-01 7.132470E-01 51 2.817E+00 5.082E+01 2.000E+00 7.100E-01 4.628E-01 0.000E+00 4.6283E-01 6.295024E-01 52 4.225E+00 5.223E+01 3.000E+00 7.100E-01 7.180E-01 0.000E+00 7.1804E-01 4.877050E-01 53 5.634E+00 5.363E+01 4.000E+00 7.100E-01 9.762E-01 0.000E+00 9.7616E-01 3.767556E-01 54 7.042E+00 5.504E+01 5.000E+00 7.100E-01 1.235E+00 0.000E+00 1.2352E+00 2.907813E-01 55 8.451E+00 5.645E+01 6.000E+00 7.100E-01 1.494E+00 0.000E+00 1.4945E+00 2.243616E-01 56 9.859E+00 5.786E+01 7.000E+00 7.100E-01 1.754E+00 0.000E+00 1.7539E+00 1.730977E-01 57 1.127E+01 5.927E+01 8.000E+00 7.100E-01 2.013E+00 0.000E+00 2.0133E+00 1.335432E-01 58 1.268E+01 6.068E+01 9.000E+00 7.100E-01 2.273E+00 0.000E+00 2.2728E+00 1.030264E-01 59 1.408E+01 6.208E+01 1.000E+01 7.100E-01 2.532E+00 0.000E+00 2.5322E+00 7.948290E-02 60 1.761E+01 6.561E+01 1.250E+01 7.100E-01 3.181E+00 0.000E+00 3.1808E+00 4.155142E-02 61 2.113E+01 6.913E+01 1.500E+01 7.100E-01 3.829E+00 0.000E+00 3.8294E+00 2.172190E-02 62 2.465E+01 7.265E+01 1.750E+01 7.100E-01 4.478E+00 0.000E+00 4.4780E+00 1.135559E-02 63 2.817E+01 7.617E+01 2.000E+01 7.100E-01 5.127E+00 0.000E+00 5.1267E+00 5.936381E-03 64 3.521E+01 8.321E+01 2.500E+01 7.100E-01 6.424E+00 0.000E+00 6.4239E+00 1.622354E-03 65 4.225E+01 9.025E+01 3.000E+01 7.100E-01 7.721E+00 0.000E+00 7.7211E+00 4.433734E-04 66 4.930E+01 9.730E+01 3.500E+01 7.100E-01 9.018E+00 0.000E+00 9.0183E+00 1.211696E-04 67 2.778E-13 9.600E+01 0.000E+00 0.000E+00 0.000E+00 0.000E+00 0.0000E+00 1.000000E+00 68 1.235E-03 4.800E+01 1.000E-01 8.100E+01 1.917E-02 6.007E-13 1.9166E-02 9.810161E-01 69 3.086E-03 4.800E+01 2.500E-01 8.100E+01 4.947E-02 0.000E+00 4.9468E-02 9.517352E-01 70 6.173E-03 4.801E+01 5.000E-01 8.100E+01 1.041E-01 0.000E+00 1.0409E-01 9.011477E-01 71 1.235E-02 4.801E+01 1.000E+00 8.100E+01 2.286E-01 0.000E+00 2.2858E-01 7.956630E-01 72 1.852E-02 4.802E+01 1.500E+00 8.100E+01 3.731E-01 0.000E+00 3.7311E-01 6.885925E-01 73 2.469E-02 4.802E+01 2.000E+00 8.100E+01 5.373E-01 0.000E+00 5.3730E-01 5.843246E-01 74 3.704E-02 4.804E+01 3.000E+00 8.100E+01 9.233E-01 0.000E+00 9.2326E-01 3.972209E-01 75 4.938E-02 4.805E+01 4.000E+00 8.100E+01 1.384E+00 0.000E+00 1.3837E+00 2.506473E-01 76 6.173E-02 4.806E+01 5.000E+00 8.100E+01 1.916E+00 0.000E+00 1.9160E+00 1.471953E-01 77 7.407E-02 4.807E+01 6.000E+00 8.100E+01 2.518E+00 0.000E+00 2.5176E+00 8.065315E-02 78 8.642E-02 4.809E+01 7.000E+00 8.100E+01 3.186E+00 1.173E-11 3.1861E+00 4.133270E-02 79 9.877E-02 4.810E+01 8.000E+00 8.100E+01 3.919E+00 1.117E-11 3.9192E+00 1.985706E-02 80 1.111E-01 4.811E+01 9.000E+00 8.100E+01 4.715E+00 1.016E-11 4.7147E+00 8.962847E-03 81 1.235E-01 4.812E+01 1.000E+01 8.100E+01 5.570E+00 8.989E-12 5.5704E+00 3.808972E-03 82 1.543E-01 4.815E+01 1.250E+01 8.100E+01 7.960E+00 7.248E-12 7.9602E+00 3.490799E-04 83 1.852E-01 4.819E+01 1.500E+01 8.100E+01 1.068E+01 3.989E-12 1.0685E+01 2.289491E-05 84 2.160E-01 4.822E+01 1.750E+01 8.100E+01 1.372E+01 9.245E-14 1.3717E+01 1.103679E-06 85 2.469E-01 4.825E+01 2.000E+01 8.100E+01 1.703E+01 9.639E-14 1.7033E+01 4.006197E-08 86 3.086E-01 4.831E+01 2.500E+01 8.100E+01 2.443E+01 0.000E+00 2.4430E+01 2.455344E-11 87 3.704E-01 4.837E+01 3.000E+01 8.100E+01 3.272E+01 1.075E-11 3.2724E+01 6.141963E-15 88 4.321E-01 4.843E+01 3.500E+01 8.100E+01 4.179E+01 1.074E-11 4.1786E+01 7.123595E-19 ------------------------------------------------------------------------------------------------------ NOTE: SF=EXP{-(lethal residual damage + lethal mutations)}. QECK TABLE: Cell survival, corrected for repopulation effects, as a function of dose and dose rate. Cell kinetic parameters are: N(0)=F0*KAP*VOL=1.00000E+00, TCC=10.0000 h, Tpot=20.000 days. ===================================================================================================================== TSIM DOSE DOSE RATE - SURVIVING FRACTION - --------- EXPECTED NUMBER OF CELLS ----------- SIM ID (day) (Gy) (Gy/h) no repop repop N(t)/N(0) N(0)*S(D) N(t)*S(D) NSC(t) --------------------------------------------------------------------------------------------------------------------- 1 4.000E+00 0.000E+00 0.000E+00 1.0000E+00 1.0000E+00 1.0000E+00 1.0000E+00 1.0000E+00 1.0000E+00 2 1.517E+00 1.000E-01 2.400E-01 9.8106E-01 9.8106E-01 1.0000E+00 9.8106E-01 9.8106E-01 9.8106E-01 3 2.043E+00 2.500E-01 2.400E-01 9.5230E-01 9.5230E-01 1.0000E+00 9.5230E-01 9.5230E-01 9.5230E-01 4 2.087E+00 5.000E-01 2.400E-01 9.0472E-01 9.0472E-01 1.0000E+00 9.0472E-01 9.0472E-01 9.0472E-01 5 2.174E+00 1.000E+00 2.400E-01 8.1454E-01 8.1454E-01 1.0000E+00 8.1454E-01 8.1454E-01 8.1454E-01 6 2.260E+00 1.500E+00 2.400E-01 7.3269E-01 7.3269E-01 1.0000E+00 7.3269E-01 7.3269E-01 7.3269E-01 7 2.347E+00 2.000E+00 2.400E-01 6.5896E-01 6.5896E-01 1.0000E+00 6.5896E-01 6.5896E-01 6.5896E-01 8 2.521E+00 3.000E+00 2.400E-01 5.3297E-01 5.3297E-01 1.0000E+00 5.3297E-01 5.3297E-01 5.3297E-01 9 2.694E+00 4.000E+00 2.400E-01 4.3106E-01 4.3106E-01 1.0000E+00 4.3106E-01 4.3106E-01 4.3106E-01 10 2.868E+00 5.000E+00 2.400E-01 3.4864E-01 3.4864E-01 1.0000E+00 3.4864E-01 3.4864E-01 3.4864E-01 11 3.042E+00 6.000E+00 2.400E-01 2.8198E-01 2.8198E-01 1.0000E+00 2.8198E-01 2.8198E-01 2.8198E-01 12 3.215E+00 7.000E+00 2.400E-01 2.2806E-01 2.2806E-01 1.0000E+00 2.2806E-01 2.2806E-01 2.2806E-01 13 3.389E+00 8.000E+00 2.400E-01 1.8445E-01 1.8445E-01 1.0000E+00 1.8445E-01 1.8445E-01 1.8445E-01 14 3.562E+00 9.000E+00 2.400E-01 1.4919E-01 1.4919E-01 1.0000E+00 1.4919E-01 1.4919E-01 1.4919E-01 15 3.736E+00 1.000E+01 2.400E-01 1.2066E-01 1.2066E-01 1.0000E+00 1.2066E-01 1.2066E-01 1.2066E-01 16 4.170E+00 1.250E+01 2.400E-01 7.0984E-02 7.0984E-02 1.0000E+00 7.0984E-02 7.0984E-02 7.0984E-02 17 4.604E+00 1.500E+01 2.400E-01 4.1759E-02 4.1759E-02 1.0000E+00 4.1759E-02 4.1759E-02 4.1759E-02 18 5.038E+00 1.750E+01 2.400E-01 2.4567E-02 2.4567E-02 1.0000E+00 2.4567E-02 2.4567E-02 2.4567E-02 19 5.472E+00 2.000E+01 2.400E-01 1.4452E-02 1.4452E-02 1.0000E+00 1.4452E-02 1.4452E-02 1.4452E-02 20 6.340E+00 2.500E+01 2.400E-01 5.0019E-03 5.0019E-03 1.0000E+00 5.0019E-03 5.0019E-03 5.0019E-03 21 7.208E+00 3.000E+01 2.400E-01 1.7311E-03 1.7311E-03 1.0000E+00 1.7311E-03 1.7311E-03 1.7311E-03 22 8.076E+00 3.500E+01 2.400E-01 5.9911E-04 5.9911E-04 1.0000E+00 5.9911E-04 5.9911E-04 5.9911E-04 23 4.000E+00 0.000E+00 0.000E+00 1.0000E+00 1.0000E+00 1.0000E+00 1.0000E+00 1.0000E+00 1.0000E+00 24 1.512E+00 1.000E-01 3.400E-01 9.8105E-01 9.8105E-01 1.0000E+00 9.8105E-01 9.8105E-01 9.8105E-01 25 2.031E+00 2.500E-01 3.400E-01 9.5215E-01 9.5215E-01 1.0000E+00 9.5215E-01 9.5215E-01 9.5215E-01 26 2.061E+00 5.000E-01 3.400E-01 9.0393E-01 9.0393E-01 1.0000E+00 9.0393E-01 9.0393E-01 9.0393E-01 27 2.123E+00 1.000E+00 3.400E-01 8.1131E-01 8.1131E-01 1.0000E+00 8.1131E-01 8.1131E-01 8.1131E-01 28 2.184E+00 1.500E+00 3.400E-01 7.2661E-01 7.2661E-01 1.0000E+00 7.2661E-01 7.2661E-01 7.2661E-01 29 2.245E+00 2.000E+00 3.400E-01 6.5033E-01 6.5033E-01 1.0000E+00 6.5033E-01 6.5033E-01 6.5033E-01 30 2.368E+00 3.000E+00 3.400E-01 5.2072E-01 5.2072E-01 1.0000E+00 5.2072E-01 5.2072E-01 5.2072E-01 31 2.490E+00 4.000E+00 3.400E-01 4.1690E-01 4.1690E-01 1.0000E+00 4.1690E-01 4.1690E-01 4.1690E-01 32 2.613E+00 5.000E+00 3.400E-01 3.3377E-01 3.3377E-01 1.0000E+00 3.3377E-01 3.3377E-01 3.3377E-01 33 2.735E+00 6.000E+00 3.400E-01 2.6722E-01 2.6722E-01 1.0000E+00 2.6722E-01 2.6722E-01 2.6722E-01 34 2.858E+00 7.000E+00 3.400E-01 2.1394E-01 2.1394E-01 1.0000E+00 2.1394E-01 2.1394E-01 2.1394E-01 35 2.980E+00 8.000E+00 3.400E-01 1.7128E-01 1.7128E-01 1.0000E+00 1.7128E-01 1.7128E-01 1.7128E-01 36 3.103E+00 9.000E+00 3.400E-01 1.3713E-01 1.3713E-01 1.0000E+00 1.3713E-01 1.3713E-01 1.3713E-01 37 3.225E+00 1.000E+01 3.400E-01 1.0979E-01 1.0979E-01 1.0000E+00 1.0979E-01 1.0979E-01 1.0979E-01 38 3.532E+00 1.250E+01 3.400E-01 6.2964E-02 6.2964E-02 1.0000E+00 6.2964E-02 6.2964E-02 6.2964E-02 39 3.838E+00 1.500E+01 3.400E-01 3.6111E-02 3.6111E-02 1.0000E+00 3.6111E-02 3.6111E-02 3.6111E-02 40 4.145E+00 1.750E+01 3.400E-01 2.0710E-02 2.0710E-02 1.0000E+00 2.0710E-02 2.0710E-02 2.0710E-02 41 4.451E+00 2.000E+01 3.400E-01 1.1878E-02 1.1878E-02 1.0000E+00 1.1878E-02 1.1878E-02 1.1878E-02 42 5.064E+00 2.500E+01 3.400E-01 3.9069E-03 3.9069E-03 1.0000E+00 3.9069E-03 3.9069E-03 3.9069E-03 43 5.676E+00 3.000E+01 3.400E-01 1.2851E-03 1.2851E-03 1.0000E+00 1.2851E-03 1.2851E-03 1.2851E-03 44 6.289E+00 3.500E+01 3.400E-01 4.2269E-04 4.2269E-04 1.0000E+00 4.2269E-04 4.2269E-04 4.2269E-04 45 4.000E+00 0.000E+00 0.000E+00 1.0000E+00 1.0000E+00 1.0000E+00 1.0000E+00 1.0000E+00 1.0000E+00 46 1.506E+00 1.000E-01 7.100E-01 9.8103E-01 9.8103E-01 1.0000E+00 9.8103E-01 9.8103E-01 9.8103E-01 47 2.015E+00 2.500E-01 7.100E-01 9.5195E-01 9.5195E-01 1.0000E+00 9.5195E-01 9.5195E-01 9.5195E-01 48 2.029E+00 5.000E-01 7.100E-01 9.0266E-01 9.0266E-01 1.0000E+00 9.0266E-01 9.0266E-01 9.0266E-01 49 2.059E+00 1.000E+00 7.100E-01 8.0509E-01 8.0509E-01 1.0000E+00 8.0509E-01 8.0509E-01 8.0509E-01 50 2.088E+00 1.500E+00 7.100E-01 7.1325E-01 7.1325E-01 1.0000E+00 7.1325E-01 7.1325E-01 7.1325E-01 51 2.117E+00 2.000E+00 7.100E-01 6.2950E-01 6.2950E-01 1.0000E+00 6.2950E-01 6.2950E-01 6.2950E-01 52 2.176E+00 3.000E+00 7.100E-01 4.8771E-01 4.8771E-01 1.0000E+00 4.8771E-01 4.8771E-01 4.8771E-01 53 2.235E+00 4.000E+00 7.100E-01 3.7676E-01 3.7676E-01 1.0000E+00 3.7676E-01 3.7676E-01 3.7676E-01 54 2.293E+00 5.000E+00 7.100E-01 2.9078E-01 2.9078E-01 1.0000E+00 2.9078E-01 2.9078E-01 2.9078E-01 55 2.352E+00 6.000E+00 7.100E-01 2.2436E-01 2.2436E-01 1.0000E+00 2.2436E-01 2.2436E-01 2.2436E-01 56 2.411E+00 7.000E+00 7.100E-01 1.7310E-01 1.7310E-01 1.0000E+00 1.7310E-01 1.7310E-01 1.7310E-01 57 2.469E+00 8.000E+00 7.100E-01 1.3354E-01 1.3354E-01 1.0000E+00 1.3354E-01 1.3354E-01 1.3354E-01 58 2.528E+00 9.000E+00 7.100E-01 1.0303E-01 1.0303E-01 1.0000E+00 1.0303E-01 1.0303E-01 1.0303E-01 59 2.587E+00 1.000E+01 7.100E-01 7.9483E-02 7.9483E-02 1.0000E+00 7.9483E-02 7.9483E-02 7.9483E-02 60 2.734E+00 1.250E+01 7.100E-01 4.1551E-02 4.1551E-02 1.0000E+00 4.1551E-02 4.1551E-02 4.1551E-02 61 2.880E+00 1.500E+01 7.100E-01 2.1722E-02 2.1722E-02 1.0000E+00 2.1722E-02 2.1722E-02 2.1722E-02 62 3.027E+00 1.750E+01 7.100E-01 1.1356E-02 1.1356E-02 1.0000E+00 1.1356E-02 1.1356E-02 1.1356E-02 63 3.174E+00 2.000E+01 7.100E-01 5.9364E-03 5.9364E-03 1.0000E+00 5.9364E-03 5.9364E-03 5.9364E-03 64 3.467E+00 2.500E+01 7.100E-01 1.6224E-03 1.6224E-03 1.0000E+00 1.6224E-03 1.6224E-03 1.6224E-03 65 3.761E+00 3.000E+01 7.100E-01 4.4337E-04 4.4337E-04 1.0000E+00 4.4337E-04 4.4337E-04 4.4337E-04 66 4.054E+00 3.500E+01 7.100E-01 1.2117E-04 1.2117E-04 1.0000E+00 1.2117E-04 1.2117E-04 1.2117E-04 67 4.000E+00 0.000E+00 0.000E+00 1.0000E+00 1.0000E+00 1.0000E+00 1.0000E+00 1.0000E+00 1.0000E+00 68 2.000E+00 1.000E-01 8.100E+01 9.8102E-01 9.8102E-01 1.0000E+00 9.8102E-01 9.8102E-01 9.8102E-01 69 2.000E+00 2.500E-01 8.100E+01 9.5174E-01 9.5174E-01 1.0000E+00 9.5174E-01 9.5174E-01 9.5174E-01 70 2.000E+00 5.000E-01 8.100E+01 9.0115E-01 9.0115E-01 1.0000E+00 9.0115E-01 9.0115E-01 9.0115E-01 71 2.001E+00 1.000E+00 8.100E+01 7.9566E-01 7.9566E-01 1.0000E+00 7.9566E-01 7.9566E-01 7.9566E-01 72 2.001E+00 1.500E+00 8.100E+01 6.8859E-01 6.8859E-01 1.0000E+00 6.8859E-01 6.8859E-01 6.8859E-01 73 2.001E+00 2.000E+00 8.100E+01 5.8432E-01 5.8432E-01 1.0000E+00 5.8432E-01 5.8432E-01 5.8432E-01 74 2.002E+00 3.000E+00 8.100E+01 3.9722E-01 3.9722E-01 1.0000E+00 3.9722E-01 3.9722E-01 3.9722E-01 75 2.002E+00 4.000E+00 8.100E+01 2.5065E-01 2.5065E-01 1.0000E+00 2.5065E-01 2.5065E-01 2.5065E-01 76 2.003E+00 5.000E+00 8.100E+01 1.4720E-01 1.4720E-01 1.0000E+00 1.4720E-01 1.4720E-01 1.4720E-01 77 2.003E+00 6.000E+00 8.100E+01 8.0653E-02 8.0653E-02 1.0000E+00 8.0653E-02 8.0653E-02 8.0653E-02 78 2.004E+00 7.000E+00 8.100E+01 4.1333E-02 4.1333E-02 1.0000E+00 4.1333E-02 4.1333E-02 4.1333E-02 79 2.004E+00 8.000E+00 8.100E+01 1.9857E-02 1.9857E-02 1.0000E+00 1.9857E-02 1.9857E-02 1.9857E-02 80 2.005E+00 9.000E+00 8.100E+01 8.9628E-03 8.9628E-03 1.0000E+00 8.9628E-03 8.9628E-03 8.9628E-03 81 2.005E+00 1.000E+01 8.100E+01 3.8090E-03 3.8090E-03 1.0000E+00 3.8090E-03 3.8090E-03 3.8090E-03 82 2.006E+00 1.250E+01 8.100E+01 3.4908E-04 3.4908E-04 1.0000E+00 3.4908E-04 3.4908E-04 3.4908E-04 83 2.008E+00 1.500E+01 8.100E+01 2.2895E-05 2.2895E-05 1.0000E+00 2.2895E-05 2.2895E-05 2.2895E-05 84 2.009E+00 1.750E+01 8.100E+01 1.1037E-06 1.1037E-06 1.0000E+00 1.1037E-06 1.1037E-06 1.1037E-06 85 2.010E+00 2.000E+01 8.100E+01 4.0062E-08 4.0062E-08 1.0000E+00 4.0062E-08 4.0062E-08 4.0062E-08 86 2.013E+00 2.500E+01 8.100E+01 2.4553E-11 2.4553E-11 1.0000E+00 2.4553E-11 2.4553E-11 2.4553E-11 87 2.015E+00 3.000E+01 8.100E+01 6.1420E-15 6.1420E-15 1.0000E+00 6.1420E-15 6.1420E-15 6.1420E-15 88 2.018E+00 3.500E+01 8.100E+01 7.1236E-19 7.1236E-19 1.0000E+00 7.1236E-19 7.1236E-19 7.1236E-19 --------------------------------------------------------------------------------------------------------------------- NOTE: N(0) is the initial number of cells (time=0 day), N(t) is the expected number of unirradiated (control) cells at TSIM, i.e., N(t)=N(0)*EXP[LN(2)*TSIM/TPOT]. The surviving fraction S(D) is the expected number of cells, per irradiated cell, that has not sustained lethal DNA damage (no corrections for repopulation effects). NSC(t) is the expected number of cells that survive irradiation, including repopulation effects (recommended method). The product N(t)*S(D) is an alternate method of estimating the surviving fraction with repopulation effects. DFAR TABLE: Mutagenesis and the induction of enhanced genetic instability (GI). Key GI model parameters are: (1-FRDL)=0.0%, NCM=1, NCG=1, and NCG*PGH*PGA=4.250E-06. ====================================================================================================== Dose Dose Rate -- NON-LETHAL MUTATIONS PER CELL -- **** PROBABILITY PER CELL **** SIM ID (Gy) (Gy/h) Mutations Residual Total AGF EGI EGI/SF ------------------------------------------------------------------------------------------------------ 1 0.000E+00 0.000E+00 0.000E+00 0.00E+00 0.00000E+00 0.000E+00 0.000E+00 0.000E+00 2 1.000E-01 2.400E-01 8.569E-01 0.00E+00 8.56874E-01 3.573E-06 3.573E-06 3.642E-06 3 2.500E-01 2.400E-01 2.144E+00 0.00E+00 2.14398E+00 8.677E-06 8.677E-06 9.112E-06 4 5.000E-01 2.400E-01 4.292E+00 0.00E+00 4.29193E+00 1.650E-05 1.650E-05 1.824E-05 5 1.000E+00 2.400E-01 8.592E+00 0.00E+00 8.59201E+00 2.974E-05 2.974E-05 3.652E-05 6 1.500E+00 2.400E-01 1.289E+01 0.00E+00 1.28936E+01 4.015E-05 4.015E-05 5.480E-05 7 2.000E+00 2.400E-01 1.720E+01 0.00E+00 1.71955E+01 4.816E-05 4.816E-05 7.308E-05 8 3.000E+00 2.400E-01 2.580E+01 0.00E+00 2.57993E+01 5.843E-05 5.843E-05 1.096E-04 9 4.000E+00 2.400E-01 3.440E+01 0.00E+00 3.44032E+01 6.302E-05 6.302E-05 1.462E-04 10 5.000E+00 2.400E-01 4.301E+01 0.00E+00 4.30070E+01 6.372E-05 6.372E-05 1.828E-04 11 6.000E+00 2.400E-01 5.161E+01 0.00E+00 5.16109E+01 6.184E-05 6.184E-05 2.193E-04 12 7.000E+00 2.400E-01 6.021E+01 0.00E+00 6.02147E+01 5.836E-05 5.836E-05 2.559E-04 13 8.000E+00 2.400E-01 6.882E+01 0.00E+00 6.88186E+01 5.394E-05 5.394E-05 2.924E-04 14 9.000E+00 2.400E-01 7.742E+01 0.00E+00 7.74225E+01 4.908E-05 4.908E-05 3.290E-04 15 1.000E+01 2.400E-01 8.603E+01 0.00E+00 8.60263E+01 4.411E-05 4.411E-05 3.655E-04 16 1.250E+01 2.400E-01 1.075E+02 0.00E+00 1.07536E+02 3.243E-05 3.243E-05 4.569E-04 17 1.500E+01 2.400E-01 1.290E+02 0.00E+00 1.29046E+02 2.290E-05 2.290E-05 5.483E-04 18 1.750E+01 2.400E-01 1.506E+02 0.00E+00 1.50555E+02 1.571E-05 1.571E-05 6.397E-04 19 2.000E+01 2.400E-01 1.721E+02 0.00E+00 1.72065E+02 1.056E-05 1.056E-05 7.310E-04 20 2.500E+01 2.400E-01 2.151E+02 0.00E+00 2.15084E+02 4.570E-06 4.570E-06 9.137E-04 21 3.000E+01 2.400E-01 2.581E+02 0.00E+00 2.58103E+02 1.898E-06 1.898E-06 1.096E-03 22 3.500E+01 2.400E-01 3.011E+02 0.00E+00 3.01123E+02 7.662E-07 7.662E-07 1.279E-03 23 0.000E+00 0.000E+00 0.000E+00 0.00E+00 0.00000E+00 0.000E+00 0.000E+00 0.000E+00 24 1.000E-01 3.400E-01 8.569E-01 0.00E+00 8.56894E-01 3.573E-06 3.573E-06 3.642E-06 25 2.500E-01 3.400E-01 2.144E+00 0.00E+00 2.14423E+00 8.677E-06 8.677E-06 9.113E-06 26 5.000E-01 3.400E-01 4.293E+00 0.00E+00 4.29340E+00 1.649E-05 1.649E-05 1.825E-05 27 1.000E+00 3.400E-01 8.599E+00 0.00E+00 8.59869E+00 2.965E-05 2.965E-05 3.654E-05 28 1.500E+00 3.400E-01 1.291E+01 0.00E+00 1.29076E+01 3.986E-05 3.986E-05 5.486E-05 29 2.000E+00 3.400E-01 1.722E+01 0.00E+00 1.72175E+01 4.759E-05 4.759E-05 7.317E-05 30 3.000E+00 3.400E-01 2.584E+01 0.00E+00 2.58383E+01 5.718E-05 5.718E-05 1.098E-04 31 4.000E+00 3.400E-01 3.446E+01 0.00E+00 3.44591E+01 6.105E-05 6.105E-05 1.464E-04 32 5.000E+00 3.400E-01 4.308E+01 0.00E+00 4.30800E+01 6.110E-05 6.110E-05 1.831E-04 33 6.000E+00 3.400E-01 5.170E+01 0.00E+00 5.17009E+01 5.871E-05 5.871E-05 2.197E-04 34 7.000E+00 3.400E-01 6.032E+01 0.00E+00 6.03218E+01 5.484E-05 5.484E-05 2.563E-04 35 8.000E+00 3.400E-01 6.894E+01 0.00E+00 6.89427E+01 5.018E-05 5.018E-05 2.930E-04 36 9.000E+00 3.400E-01 7.756E+01 0.00E+00 7.75636E+01 4.520E-05 4.520E-05 3.296E-04 37 1.000E+01 3.400E-01 8.618E+01 0.00E+00 8.61845E+01 4.021E-05 4.021E-05 3.662E-04 38 1.250E+01 3.400E-01 1.077E+02 0.00E+00 1.07737E+02 2.882E-05 2.882E-05 4.578E-04 39 1.500E+01 3.400E-01 1.293E+02 0.00E+00 1.29289E+02 1.984E-05 1.984E-05 5.493E-04 40 1.750E+01 3.400E-01 1.508E+02 0.00E+00 1.50841E+02 1.327E-05 1.327E-05 6.409E-04 41 2.000E+01 3.400E-01 1.724E+02 0.00E+00 1.72394E+02 8.699E-06 8.699E-06 7.324E-04 42 2.500E+01 3.400E-01 2.155E+02 0.00E+00 2.15498E+02 3.577E-06 3.577E-06 9.154E-04 43 3.000E+01 3.400E-01 2.586E+02 0.00E+00 2.58603E+02 1.412E-06 1.412E-06 1.098E-03 44 3.500E+01 3.400E-01 3.017E+02 0.00E+00 3.01707E+02 5.417E-07 5.417E-07 1.281E-03 45 0.000E+00 0.000E+00 0.000E+00 0.00E+00 0.00000E+00 0.000E+00 0.000E+00 0.000E+00 46 1.000E-01 7.100E-01 8.569E-01 0.00E+00 8.56920E-01 3.573E-06 3.573E-06 3.642E-06 47 2.500E-01 7.100E-01 2.145E+00 0.00E+00 2.14459E+00 8.677E-06 8.677E-06 9.114E-06 48 5.000E-01 7.100E-01 4.296E+00 0.00E+00 4.29575E+00 1.648E-05 1.648E-05 1.826E-05 49 1.000E+00 7.100E-01 8.612E+00 0.00E+00 8.61161E+00 2.947E-05 2.947E-05 3.660E-05 50 1.500E+00 7.100E-01 1.294E+01 0.00E+00 1.29387E+01 3.922E-05 3.922E-05 5.499E-05 51 2.000E+00 7.100E-01 1.727E+01 0.00E+00 1.72722E+01 4.621E-05 4.621E-05 7.340E-05 52 3.000E+00 7.100E-01 2.595E+01 0.00E+00 2.59481E+01 5.378E-05 5.378E-05 1.103E-04 53 4.000E+00 7.100E-01 3.463E+01 0.00E+00 3.46288E+01 5.544E-05 5.544E-05 1.472E-04 54 5.000E+00 7.100E-01 4.331E+01 0.00E+00 4.33111E+01 5.352E-05 5.352E-05 1.841E-04 55 6.000E+00 7.100E-01 5.199E+01 0.00E+00 5.19939E+01 4.957E-05 4.957E-05 2.209E-04 56 7.000E+00 7.100E-01 6.068E+01 0.00E+00 6.06768E+01 4.463E-05 4.463E-05 2.578E-04 57 8.000E+00 7.100E-01 6.936E+01 0.00E+00 6.93597E+01 3.936E-05 3.936E-05 2.947E-04 58 9.000E+00 7.100E-01 7.804E+01 0.00E+00 7.80427E+01 3.417E-05 3.417E-05 3.316E-04 59 1.000E+01 7.100E-01 8.673E+01 0.00E+00 8.67256E+01 2.929E-05 2.929E-05 3.685E-04 60 1.250E+01 7.100E-01 1.084E+02 0.00E+00 1.08433E+02 1.914E-05 1.914E-05 4.607E-04 61 1.500E+01 7.100E-01 1.301E+02 0.00E+00 1.30140E+02 1.201E-05 1.201E-05 5.529E-04 62 1.750E+01 7.100E-01 1.518E+02 0.00E+00 1.51848E+02 7.326E-06 7.326E-06 6.451E-04 63 2.000E+01 7.100E-01 1.736E+02 0.00E+00 1.73555E+02 4.377E-06 4.377E-06 7.373E-04 64 2.500E+01 7.100E-01 2.170E+02 0.00E+00 2.16970E+02 1.495E-06 1.495E-06 9.217E-04 65 3.000E+01 7.100E-01 2.604E+02 0.00E+00 2.60385E+02 4.904E-07 4.904E-07 1.106E-03 66 3.500E+01 7.100E-01 3.038E+02 0.00E+00 3.03800E+02 1.563E-07 1.563E-07 1.290E-03 67 0.000E+00 0.000E+00 0.000E+00 0.00E+00 0.00000E+00 0.000E+00 0.000E+00 0.000E+00 68 1.000E-01 8.100E+01 8.569E-01 0.00E+00 8.56946E-01 3.573E-06 3.573E-06 3.642E-06 69 2.500E-01 8.100E+01 2.145E+00 0.00E+00 2.14497E+00 8.676E-06 8.676E-06 9.116E-06 70 5.000E-01 8.100E+01 4.299E+00 0.00E+00 4.29858E+00 1.646E-05 1.646E-05 1.827E-05 71 1.000E+00 8.100E+01 8.631E+00 0.00E+00 8.63139E+00 2.919E-05 2.919E-05 3.668E-05 72 1.500E+00 8.100E+01 1.300E+01 0.00E+00 1.29978E+01 3.804E-05 3.804E-05 5.524E-05 73 2.000E+00 8.100E+01 1.740E+01 0.00E+00 1.73972E+01 4.320E-05 4.320E-05 7.394E-05 74 3.000E+00 8.100E+01 2.629E+01 0.00E+00 2.62926E+01 4.438E-05 4.438E-05 1.117E-04 75 4.000E+00 8.100E+01 3.531E+01 0.00E+00 3.53130E+01 3.761E-05 3.761E-05 1.501E-04 76 5.000E+00 8.100E+01 4.445E+01 0.00E+00 4.44539E+01 2.781E-05 2.781E-05 1.889E-04 77 6.000E+00 8.100E+01 5.371E+01 0.00E+00 5.37112E+01 1.841E-05 1.841E-05 2.282E-04 78 7.000E+00 8.100E+01 6.308E+01 0.00E+00 6.30806E+01 1.108E-05 1.108E-05 2.681E-04 79 8.000E+00 8.100E+01 7.256E+01 0.00E+00 7.25584E+01 6.122E-06 6.122E-06 3.083E-04 80 9.000E+00 8.100E+01 8.214E+01 0.00E+00 8.21409E+01 3.128E-06 3.128E-06 3.490E-04 81 1.000E+01 8.100E+01 9.182E+01 0.00E+00 9.18245E+01 1.486E-06 1.486E-06 3.902E-04 82 1.250E+01 8.100E+01 1.165E+02 0.00E+00 1.16454E+02 1.727E-07 1.727E-07 4.948E-04 83 1.500E+01 8.100E+01 1.416E+02 0.00E+00 1.41644E+02 1.378E-08 1.378E-08 6.018E-04 84 1.750E+01 8.100E+01 1.674E+02 0.00E+00 1.67351E+02 7.847E-10 7.847E-10 7.110E-04 85 2.000E+01 8.100E+01 1.935E+02 0.00E+00 1.93535E+02 3.294E-11 3.294E-11 8.222E-04 86 2.500E+01 8.100E+01 2.472E+02 0.00E+00 2.47185E+02 2.578E-14 2.578E-14 1.050E-03 87 3.000E+01 8.100E+01 3.023E+02 0.00E+00 3.02339E+02 7.887E-18 7.887E-18 1.284E-03 88 3.500E+01 8.100E+01 3.588E+02 0.00E+00 3.58783E+02 1.085E-21 1.085E-21 1.524E-03 ------------------------------------------------------------------------------------------------------ AGF: function or expression of at least 1 of the 1 critical gene targets is altered. EGI: altered gene function or expression causes enhanced genetic instability. NEOM TABLE: Neoplastic transformation as a function of dose and dose rate at t=42.000 days. Parameters: TFS=1.1500E-05 (1/wk), TFU=2.0000E-03 (1/wk), NCM=1, NCG=1, and NCG*PGH*PGA=4.3E-06. ====================================================================================================== Dose Dose Rate Non-Lethal Genetic Instability *** TRANSFORMATION FREQUENCY *** SIM ID (Gy) (Gy/h) Mutations EGI EGI/SF BKG TPS TPI ------------------------------------------------------------------------------------------------------ 1 0.000E+00 0.000E+00 0.000E+00 0.000E+00 0.000E+00 6.8995E-05 6.8995E-05 6.8995E-05 2 1.000E-01 2.400E-01 8.569E-01 3.573E-06 3.642E-06 6.8995E-05 6.9038E-05 6.7731E-05 3 2.500E-01 2.400E-01 2.144E+00 8.677E-06 9.112E-06 6.8995E-05 6.9103E-05 6.5807E-05 4 5.000E-01 2.400E-01 4.292E+00 1.650E-05 1.824E-05 6.8994E-05 6.9212E-05 6.2617E-05 5 1.000E+00 2.400E-01 8.592E+00 2.974E-05 3.652E-05 6.8993E-05 6.9428E-05 5.6552E-05 6 1.500E+00 2.400E-01 1.289E+01 4.015E-05 5.480E-05 6.8991E-05 6.9645E-05 5.1029E-05 7 2.000E+00 2.400E-01 1.720E+01 4.816E-05 7.308E-05 6.8990E-05 6.9862E-05 4.6036E-05 8 3.000E+00 2.400E-01 2.580E+01 5.843E-05 1.096E-04 6.8988E-05 7.0295E-05 3.7465E-05 9 4.000E+00 2.400E-01 3.440E+01 6.302E-05 1.462E-04 6.8985E-05 7.0729E-05 3.0488E-05 10 5.000E+00 2.400E-01 4.301E+01 6.372E-05 1.828E-04 6.8983E-05 7.1163E-05 2.4810E-05 11 6.000E+00 2.400E-01 5.161E+01 6.184E-05 2.193E-04 6.8980E-05 7.1596E-05 2.0188E-05 12 7.000E+00 2.400E-01 6.021E+01 5.836E-05 2.559E-04 6.8978E-05 7.2030E-05 1.6427E-05 13 8.000E+00 2.400E-01 6.882E+01 5.394E-05 2.924E-04 6.8975E-05 7.2463E-05 1.3366E-05 14 9.000E+00 2.400E-01 7.742E+01 4.908E-05 3.290E-04 6.8973E-05 7.2897E-05 1.0875E-05 15 1.000E+01 2.400E-01 8.603E+01 4.411E-05 3.655E-04 6.8970E-05 7.3330E-05 8.8481E-06 16 1.250E+01 2.400E-01 1.075E+02 3.243E-05 4.569E-04 6.8964E-05 7.4414E-05 5.2822E-06 17 1.500E+01 2.400E-01 1.290E+02 2.290E-05 5.483E-04 6.8957E-05 7.5498E-05 3.1527E-06 18 1.750E+01 2.400E-01 1.506E+02 1.571E-05 6.397E-04 6.8951E-05 7.6581E-05 1.8813E-06 19 2.000E+01 2.400E-01 1.721E+02 1.056E-05 7.310E-04 6.8945E-05 7.7664E-05 1.1224E-06 20 2.500E+01 2.400E-01 2.151E+02 4.570E-06 9.137E-04 6.8932E-05 7.9831E-05 3.9930E-07 21 3.000E+01 2.400E-01 2.581E+02 1.898E-06 1.096E-03 6.8920E-05 8.1997E-05 1.4194E-07 22 3.500E+01 2.400E-01 3.011E+02 7.662E-07 1.279E-03 6.8907E-05 8.4163E-05 5.0423E-08 23 0.000E+00 0.000E+00 0.000E+00 0.000E+00 0.000E+00 6.8995E-05 6.8995E-05 6.8995E-05 24 1.000E-01 3.400E-01 8.569E-01 3.573E-06 3.642E-06 6.8995E-05 6.9038E-05 6.7730E-05 25 2.500E-01 3.400E-01 2.144E+00 8.677E-06 9.113E-06 6.8995E-05 6.9103E-05 6.5797E-05 26 5.000E-01 3.400E-01 4.293E+00 1.649E-05 1.825E-05 6.8994E-05 6.9212E-05 6.2562E-05 27 1.000E+00 3.400E-01 8.599E+00 2.965E-05 3.654E-05 6.8993E-05 6.9429E-05 5.6328E-05 28 1.500E+00 3.400E-01 1.291E+01 3.986E-05 5.486E-05 6.8991E-05 6.9646E-05 5.0606E-05 29 2.000E+00 3.400E-01 1.722E+01 4.759E-05 7.317E-05 6.8990E-05 6.9863E-05 4.5434E-05 30 3.000E+00 3.400E-01 2.584E+01 5.718E-05 1.098E-04 6.8988E-05 7.0297E-05 3.6605E-05 31 4.000E+00 3.400E-01 3.446E+01 6.105E-05 1.464E-04 6.8985E-05 7.0732E-05 2.9488E-05 32 5.000E+00 3.400E-01 4.308E+01 6.110E-05 1.831E-04 6.8983E-05 7.1166E-05 2.3753E-05 33 6.000E+00 3.400E-01 5.170E+01 5.871E-05 2.197E-04 6.8980E-05 7.1601E-05 1.9133E-05 34 7.000E+00 3.400E-01 6.032E+01 5.484E-05 2.563E-04 6.8978E-05 7.2035E-05 1.5411E-05 35 8.000E+00 3.400E-01 6.894E+01 5.018E-05 2.930E-04 6.8975E-05 7.2470E-05 1.2413E-05 36 9.000E+00 3.400E-01 7.756E+01 4.520E-05 3.296E-04 6.8972E-05 7.2904E-05 9.9972E-06 37 1.000E+01 3.400E-01 8.618E+01 4.021E-05 3.662E-04 6.8970E-05 7.3338E-05 8.0515E-06 38 1.250E+01 3.400E-01 1.077E+02 2.882E-05 4.578E-04 6.8964E-05 7.4424E-05 4.6860E-06 39 1.500E+01 3.400E-01 1.293E+02 1.984E-05 5.493E-04 6.8957E-05 7.5510E-05 2.7267E-06 40 1.750E+01 3.400E-01 1.508E+02 1.327E-05 6.409E-04 6.8951E-05 7.6595E-05 1.5863E-06 41 2.000E+01 3.400E-01 1.724E+02 8.699E-06 7.324E-04 6.8945E-05 7.7681E-05 9.2268E-07 42 2.500E+01 3.400E-01 2.155E+02 3.577E-06 9.154E-04 6.8932E-05 7.9852E-05 3.1197E-07 43 3.000E+01 3.400E-01 2.586E+02 1.412E-06 1.098E-03 6.8919E-05 8.2022E-05 1.0541E-07 44 3.500E+01 3.400E-01 3.017E+02 5.417E-07 1.281E-03 6.8907E-05 8.4192E-05 3.5588E-08 45 0.000E+00 0.000E+00 0.000E+00 0.000E+00 0.000E+00 6.8995E-05 6.8995E-05 6.8995E-05 46 1.000E-01 7.100E-01 8.569E-01 3.573E-06 3.642E-06 6.8995E-05 6.9038E-05 6.7729E-05 47 2.500E-01 7.100E-01 2.145E+00 8.677E-06 9.114E-06 6.8995E-05 6.9103E-05 6.5783E-05 48 5.000E-01 7.100E-01 4.296E+00 1.648E-05 1.826E-05 6.8994E-05 6.9212E-05 6.2475E-05 49 1.000E+00 7.100E-01 8.612E+00 2.947E-05 3.660E-05 6.8993E-05 6.9429E-05 5.5897E-05 50 1.500E+00 7.100E-01 1.294E+01 3.922E-05 5.499E-05 6.8991E-05 6.9647E-05 4.9676E-05 51 2.000E+00 7.100E-01 1.727E+01 4.621E-05 7.340E-05 6.8990E-05 6.9866E-05 4.3981E-05 52 3.000E+00 7.100E-01 2.595E+01 5.378E-05 1.103E-04 6.8988E-05 7.0303E-05 3.4287E-05 53 4.000E+00 7.100E-01 3.463E+01 5.544E-05 1.472E-04 6.8985E-05 7.0740E-05 2.6652E-05 54 5.000E+00 7.100E-01 4.331E+01 5.352E-05 1.841E-04 6.8983E-05 7.1178E-05 2.0697E-05 55 6.000E+00 7.100E-01 5.199E+01 4.957E-05 2.209E-04 6.8980E-05 7.1616E-05 1.6068E-05 56 7.000E+00 7.100E-01 6.068E+01 4.463E-05 2.578E-04 6.8977E-05 7.2053E-05 1.2472E-05 57 8.000E+00 7.100E-01 6.936E+01 3.936E-05 2.947E-04 6.8975E-05 7.2491E-05 9.6806E-06 58 9.000E+00 7.100E-01 7.804E+01 3.417E-05 3.316E-04 6.8972E-05 7.2928E-05 7.5135E-06 59 1.000E+01 7.100E-01 8.673E+01 2.929E-05 3.685E-04 6.8970E-05 7.3366E-05 5.8313E-06 60 1.250E+01 7.100E-01 1.084E+02 1.914E-05 4.607E-04 6.8963E-05 7.4459E-05 3.0939E-06 61 1.500E+01 7.100E-01 1.301E+02 1.201E-05 5.529E-04 6.8957E-05 7.5553E-05 1.6411E-06 62 1.750E+01 7.100E-01 1.518E+02 7.326E-06 6.451E-04 6.8951E-05 7.6646E-05 8.7036E-07 63 2.000E+01 7.100E-01 1.736E+02 4.377E-06 7.373E-04 6.8944E-05 7.7740E-05 4.6149E-07 64 2.500E+01 7.100E-01 2.170E+02 1.495E-06 9.217E-04 6.8932E-05 7.9926E-05 1.2967E-07 65 3.000E+01 7.100E-01 2.604E+02 4.904E-07 1.106E-03 6.8919E-05 8.2112E-05 3.6406E-08 66 3.500E+01 7.100E-01 3.038E+02 1.563E-07 1.290E-03 6.8906E-05 8.4297E-05 1.0214E-08 67 0.000E+00 0.000E+00 0.000E+00 0.000E+00 0.000E+00 6.8995E-05 6.8995E-05 6.8995E-05 68 1.000E-01 8.100E+01 8.569E-01 3.573E-06 3.642E-06 6.8995E-05 6.9038E-05 6.7728E-05 69 2.500E-01 8.100E+01 2.145E+00 8.676E-06 9.116E-06 6.8995E-05 6.9103E-05 6.5768E-05 70 5.000E-01 8.100E+01 4.299E+00 1.646E-05 1.827E-05 6.8994E-05 6.9212E-05 6.2370E-05 71 1.000E+00 8.100E+01 8.631E+00 2.919E-05 3.668E-05 6.8993E-05 6.9430E-05 5.5243E-05 72 1.500E+00 8.100E+01 1.300E+01 3.804E-05 5.524E-05 6.8991E-05 6.9650E-05 4.7961E-05 73 2.000E+00 8.100E+01 1.740E+01 4.320E-05 7.394E-05 6.8990E-05 6.9872E-05 4.0828E-05 74 3.000E+00 8.100E+01 2.629E+01 4.438E-05 1.117E-04 6.8988E-05 7.0320E-05 2.7933E-05 75 4.000E+00 8.100E+01 3.531E+01 3.761E-05 1.501E-04 6.8985E-05 7.0775E-05 1.7740E-05 76 5.000E+00 8.100E+01 4.445E+01 2.781E-05 1.889E-04 6.8982E-05 7.1236E-05 1.0486E-05 77 6.000E+00 8.100E+01 5.371E+01 1.841E-05 2.282E-04 6.8979E-05 7.1702E-05 5.7830E-06 78 7.000E+00 8.100E+01 6.308E+01 1.108E-05 2.681E-04 6.8977E-05 7.2174E-05 2.9832E-06 79 8.000E+00 8.100E+01 7.256E+01 6.122E-06 3.083E-04 6.8974E-05 7.2652E-05 1.4426E-06 80 9.000E+00 8.100E+01 8.214E+01 3.128E-06 3.490E-04 6.8971E-05 7.3135E-05 6.5549E-07 81 1.000E+01 8.100E+01 9.182E+01 1.486E-06 3.902E-04 6.8968E-05 7.3622E-05 2.8043E-07 82 1.250E+01 8.100E+01 1.165E+02 1.727E-07 4.948E-04 6.8961E-05 7.4863E-05 2.6133E-08 83 1.500E+01 8.100E+01 1.416E+02 1.378E-08 6.018E-04 6.8954E-05 7.6132E-05 1.7430E-09 84 1.750E+01 8.100E+01 1.674E+02 7.847E-10 7.110E-04 6.8946E-05 7.7427E-05 8.5455E-11 85 2.000E+01 8.100E+01 1.935E+02 3.294E-11 8.222E-04 6.8938E-05 7.8746E-05 3.1547E-12 86 2.500E+01 8.100E+01 2.472E+02 2.578E-14 1.050E-03 6.8923E-05 8.1447E-05 1.9998E-15 87 3.000E+01 8.100E+01 3.023E+02 7.887E-18 1.284E-03 6.8907E-05 8.4224E-05 5.1730E-19 88 3.500E+01 8.100E+01 3.588E+02 1.085E-21 1.524E-03 6.8890E-05 8.7065E-05 6.2021E-23 ------------------------------------------------------------------------------------------------------ TPS: Transformation frequency per survivor, TPI: Transformation frequency per irradiated cell EGI: Probabilty random mutational events caused enhanced genetic instability (EGI). BKG: Background (spontaneous) cell transformation frequency TLKM TABLE: LQ model dose protraction factor(s) and cell survival estimates (FRDL=100.0%). LQ model parameters are: alpha = 0.1875 (1/Gy), alpha/beta = 4.5096 (Gy), lamda1 = 8.043E-01 (1/h), lamda2 = 7.900E-01 (1/h). ================================================================================================================= --- Duration (h) --- Dose Dose Rate* *********** G FACTOR *********** ******* SF(dose) ******* SIM ID Exposure Sim (Gy) (Gy/h) GL1 GL2 GEFF SF1 SF2 ----------------------------------------------------------------------------------------------------------------- 1 2.778E-13 9.600E+01 0.000E+00 0.000E+00 0.000E+00 0.000E+00 0.000E+00 1.0000E+00 1.000000E+00 2 4.167E-01 3.642E+01 1.000E-01 2.400E-01 8.971E-01 8.987E-01 8.966E-01 9.8106E-01 9.810578E-01 3 1.042E+00 4.904E+01 2.500E-01 2.400E-01 7.706E-01 7.740E-01 7.698E-01 9.5229E-01 9.522972E-01 4 2.083E+00 5.008E+01 5.000E-01 2.400E-01 6.146E-01 6.192E-01 6.134E-01 9.0470E-01 9.047183E-01 5 4.167E+00 5.217E+01 1.000E+00 2.400E-01 4.249E-01 4.299E-01 4.237E-01 8.1447E-01 8.145435E-01 6 6.250E+00 5.425E+01 1.500E+00 2.400E-01 3.192E-01 3.236E-01 3.181E-01 7.3256E-01 7.326941E-01 7 8.333E+00 5.633E+01 2.000E+00 2.400E-01 2.539E-01 2.577E-01 2.530E-01 6.5877E-01 6.589588E-01 8 1.250E+01 6.050E+01 3.000E+00 2.400E-01 1.791E-01 1.820E-01 1.784E-01 5.3271E-01 5.329663E-01 9 1.667E+01 6.467E+01 4.000E+00 2.400E-01 1.381E-01 1.404E-01 1.375E-01 4.3076E-01 4.310600E-01 10 2.083E+01 6.883E+01 5.000E+00 2.400E-01 1.122E-01 1.141E-01 1.118E-01 3.4833E-01 3.486386E-01 11 2.500E+01 7.300E+01 6.000E+00 2.400E-01 9.452E-02 9.613E-02 9.411E-02 2.8167E-01 2.819767E-01 12 2.917E+01 7.717E+01 7.000E+00 2.400E-01 8.162E-02 8.303E-02 8.126E-02 2.2777E-01 2.280610E-01 13 3.333E+01 8.133E+01 8.000E+00 2.400E-01 7.182E-02 7.306E-02 7.150E-02 1.8418E-01 1.844544E-01 14 3.750E+01 8.550E+01 9.000E+00 2.400E-01 6.411E-02 6.523E-02 6.383E-02 1.4893E-01 1.491855E-01 15 4.167E+01 8.967E+01 1.000E+01 2.400E-01 5.790E-02 5.891E-02 5.764E-02 1.2043E-01 1.206603E-01 16 5.208E+01 1.001E+02 1.250E+01 2.400E-01 4.660E-02 4.742E-02 4.639E-02 7.0813E-02 7.098377E-02 17 6.250E+01 1.105E+02 1.500E+01 2.400E-01 3.899E-02 3.968E-02 3.882E-02 4.1638E-02 4.175933E-02 18 7.292E+01 1.209E+02 1.750E+01 2.400E-01 3.352E-02 3.412E-02 3.337E-02 2.4483E-02 2.456677E-02 19 8.333E+01 1.313E+02 2.000E+01 2.400E-01 2.939E-02 2.992E-02 2.926E-02 1.4396E-02 1.445249E-02 20 1.042E+02 1.522E+02 2.500E+01 2.400E-01 2.359E-02 2.401E-02 2.348E-02 4.9772E-03 5.001861E-03 21 1.250E+02 1.730E+02 3.000E+01 2.400E-01 1.969E-02 2.005E-02 1.961E-02 1.7208E-03 1.731094E-03 22 1.458E+02 1.938E+02 3.500E+01 2.400E-01 1.691E-02 1.721E-02 1.683E-02 5.9495E-04 5.991143E-04 23 2.778E-13 9.600E+01 0.000E+00 0.000E+00 0.000E+00 0.000E+00 0.000E+00 1.0000E+00 1.000000E+00 24 2.941E-01 3.629E+01 1.000E-01 3.400E-01 9.256E-01 9.268E-01 9.250E-01 9.8105E-01 9.810462E-01 25 7.353E-01 4.874E+01 2.500E-01 3.400E-01 8.289E-01 8.315E-01 8.277E-01 9.5215E-01 9.521539E-01 26 1.471E+00 4.947E+01 5.000E-01 3.400E-01 6.994E-01 7.034E-01 6.976E-01 9.0390E-01 9.039272E-01 27 2.941E+00 5.094E+01 1.000E+00 3.400E-01 5.216E-01 5.266E-01 5.194E-01 8.1120E-01 8.113083E-01 28 4.412E+00 5.241E+01 1.500E+00 3.400E-01 4.094E-01 4.142E-01 4.072E-01 7.2640E-01 7.266131E-01 29 5.882E+00 5.388E+01 2.000E+00 3.400E-01 3.342E-01 3.386E-01 3.322E-01 6.5002E-01 6.503343E-01 30 8.824E+00 5.682E+01 3.000E+00 3.400E-01 2.421E-01 2.458E-01 2.405E-01 5.2027E-01 5.207208E-01 31 1.176E+01 5.976E+01 4.000E+00 3.400E-01 1.890E-01 1.920E-01 1.877E-01 4.1636E-01 4.168969E-01 32 1.471E+01 6.271E+01 5.000E+00 3.400E-01 1.548E-01 1.573E-01 1.537E-01 3.3321E-01 3.337708E-01 33 1.765E+01 6.565E+01 6.000E+00 3.400E-01 1.310E-01 1.332E-01 1.300E-01 2.6666E-01 2.672192E-01 34 2.059E+01 6.859E+01 7.000E+00 3.400E-01 1.135E-01 1.154E-01 1.126E-01 2.1341E-01 2.139375E-01 35 2.353E+01 7.153E+01 8.000E+00 3.400E-01 1.001E-01 1.018E-01 9.935E-02 1.7078E-01 1.712798E-01 36 2.647E+01 7.447E+01 9.000E+00 3.400E-01 8.953E-02 9.106E-02 8.885E-02 1.3668E-01 1.371278E-01 37 2.941E+01 7.741E+01 1.000E+01 3.400E-01 8.097E-02 8.237E-02 8.036E-02 1.0938E-01 1.097855E-01 38 3.676E+01 8.476E+01 1.250E+01 3.400E-01 6.535E-02 6.649E-02 6.485E-02 6.2668E-02 6.296410E-02 39 4.412E+01 9.212E+01 1.500E+01 3.400E-01 5.477E-02 5.573E-02 5.435E-02 3.5905E-02 3.611114E-02 40 5.147E+01 9.947E+01 1.750E+01 3.400E-01 4.714E-02 4.797E-02 4.678E-02 2.0571E-02 2.071044E-02 41 5.882E+01 1.068E+02 2.000E+01 3.400E-01 4.138E-02 4.211E-02 4.106E-02 1.1786E-02 1.187784E-02 42 7.353E+01 1.215E+02 2.500E+01 3.400E-01 3.325E-02 3.384E-02 3.299E-02 3.8689E-03 3.906914E-03 43 8.824E+01 1.362E+02 3.000E+01 3.400E-01 2.778E-02 2.828E-02 2.757E-02 1.2700E-03 1.285080E-03 44 1.029E+02 1.509E+02 3.500E+01 3.400E-01 2.386E-02 2.429E-02 2.368E-02 4.1689E-04 4.226945E-04 45 2.778E-13 9.600E+01 0.000E+00 0.000E+00 0.000E+00 0.000E+00 0.000E+00 1.0000E+00 1.000000E+00 46 1.408E-01 3.614E+01 1.000E-01 7.100E-01 9.633E-01 9.639E-01 9.625E-01 9.8103E-01 9.810309E-01 47 3.521E-01 4.835E+01 2.500E-01 7.100E-01 9.119E-01 9.134E-01 9.102E-01 9.5194E-01 9.519496E-01 48 7.042E-01 4.870E+01 5.000E-01 7.100E-01 8.352E-01 8.377E-01 8.322E-01 9.0263E-01 9.026628E-01 49 1.408E+00 4.941E+01 1.000E+00 7.100E-01 7.090E-01 7.130E-01 7.045E-01 8.0491E-01 8.050882E-01 50 2.113E+00 5.011E+01 1.500E+00 7.100E-01 6.110E-01 6.156E-01 6.056E-01 7.1283E-01 7.132470E-01 51 2.817E+00 5.082E+01 2.000E+00 7.100E-01 5.336E-01 5.385E-01 5.279E-01 6.2881E-01 6.295024E-01 52 4.225E+00 5.223E+01 3.000E+00 7.100E-01 4.211E-01 4.260E-01 4.156E-01 4.8652E-01 4.877050E-01 53 5.634E+00 5.363E+01 4.000E+00 7.100E-01 3.450E-01 3.496E-01 3.399E-01 3.7525E-01 3.767556E-01 54 7.042E+00 5.504E+01 5.000E+00 7.100E-01 2.910E-01 2.951E-01 2.863E-01 2.8913E-01 2.907813E-01 55 8.451E+00 5.645E+01 6.000E+00 7.100E-01 2.510E-01 2.547E-01 2.468E-01 2.2271E-01 2.243616E-01 56 9.859E+00 5.786E+01 7.000E+00 7.100E-01 2.204E-01 2.238E-01 2.166E-01 1.7152E-01 1.730977E-01 57 1.127E+01 5.927E+01 8.000E+00 7.100E-01 1.963E-01 1.994E-01 1.929E-01 1.3210E-01 1.335432E-01 58 1.268E+01 6.068E+01 9.000E+00 7.100E-01 1.769E-01 1.798E-01 1.737E-01 1.0174E-01 1.030264E-01 59 1.408E+01 6.208E+01 1.000E+01 7.100E-01 1.610E-01 1.636E-01 1.580E-01 7.8351E-02 7.948290E-02 60 1.761E+01 6.561E+01 1.250E+01 7.100E-01 1.313E-01 1.335E-01 1.288E-01 4.0782E-02 4.155142E-02 61 2.113E+01 6.913E+01 1.500E+01 7.100E-01 1.108E-01 1.126E-01 1.087E-01 2.1227E-02 2.172190E-02 62 2.465E+01 7.265E+01 1.750E+01 7.100E-01 9.580E-02 9.743E-02 9.397E-02 1.1049E-02 1.135559E-02 63 2.817E+01 7.617E+01 2.000E+01 7.100E-01 8.438E-02 8.583E-02 8.276E-02 5.7510E-03 5.936381E-03 64 3.521E+01 8.321E+01 2.500E+01 7.100E-01 6.813E-02 6.931E-02 6.681E-02 1.5581E-03 1.622354E-03 65 4.225E+01 9.025E+01 3.000E+01 7.100E-01 5.712E-02 5.812E-02 5.600E-02 4.2213E-04 4.433734E-04 66 4.930E+01 9.730E+01 3.500E+01 7.100E-01 4.917E-02 5.003E-02 4.821E-02 1.1437E-04 1.211696E-04 67 2.778E-13 9.600E+01 0.000E+00 0.000E+00 0.000E+00 0.000E+00 0.000E+00 1.0000E+00 1.000000E+00 68 1.235E-03 4.800E+01 1.000E-01 8.100E+01 9.997E-01 9.997E-01 9.988E-01 9.8102E-01 9.810161E-01 69 3.086E-03 4.800E+01 2.500E-01 8.100E+01 9.992E-01 9.992E-01 9.969E-01 9.5173E-01 9.517352E-01 70 6.173E-03 4.801E+01 5.000E-01 8.100E+01 9.983E-01 9.984E-01 9.938E-01 9.0111E-01 9.011477E-01 71 1.235E-02 4.801E+01 1.000E+00 8.100E+01 9.967E-01 9.968E-01 9.877E-01 7.9537E-01 7.956630E-01 72 1.852E-02 4.802E+01 1.500E+00 8.100E+01 9.951E-01 9.951E-01 9.817E-01 6.8773E-01 6.885925E-01 73 2.469E-02 4.802E+01 2.000E+00 8.100E+01 9.934E-01 9.935E-01 9.757E-01 5.8260E-01 5.843246E-01 74 3.704E-02 4.804E+01 3.000E+00 8.100E+01 9.901E-01 9.903E-01 9.640E-01 3.9334E-01 3.972209E-01 75 4.938E-02 4.805E+01 4.000E+00 8.100E+01 9.869E-01 9.871E-01 9.525E-01 2.4497E-01 2.506473E-01 76 6.173E-02 4.806E+01 5.000E+00 8.100E+01 9.837E-01 9.839E-01 9.413E-01 1.4084E-01 1.471953E-01 77 7.407E-02 4.807E+01 6.000E+00 8.100E+01 9.804E-01 9.808E-01 9.303E-01 7.4813E-02 8.065315E-02 78 8.642E-02 4.809E+01 7.000E+00 8.100E+01 9.772E-01 9.776E-01 9.196E-01 3.6745E-02 4.133270E-02 79 9.877E-02 4.810E+01 8.000E+00 8.100E+01 9.740E-01 9.745E-01 9.091E-01 1.6700E-02 1.985706E-02 80 1.111E-01 4.811E+01 9.000E+00 8.100E+01 9.709E-01 9.714E-01 8.988E-01 7.0284E-03 8.962847E-03 81 1.235E-01 4.812E+01 1.000E+01 8.100E+01 9.677E-01 9.683E-01 8.887E-01 2.7414E-03 3.808972E-03 82 1.543E-01 4.815E+01 1.250E+01 8.100E+01 9.599E-01 9.606E-01 8.645E-01 1.8764E-04 3.490799E-04 83 1.852E-01 4.819E+01 1.500E+01 8.100E+01 9.521E-01 9.530E-01 8.414E-01 8.1133E-06 2.289491E-05 84 2.160E-01 4.822E+01 1.750E+01 8.100E+01 9.445E-01 9.455E-01 8.195E-01 2.2412E-07 1.103679E-06 85 2.469E-01 4.825E+01 2.000E+01 8.100E+01 9.370E-01 9.380E-01 7.986E-01 3.9986E-09 4.006197E-08 86 3.086E-01 4.831E+01 2.500E+01 8.100E+01 9.221E-01 9.234E-01 7.597E-01 3.5783E-13 2.455344E-11 87 3.704E-01 4.837E+01 3.000E+01 8.100E+01 9.077E-01 9.092E-01 7.241E-01 6.3136E-18 6.141963E-15 88 4.321E-01 4.843E+01 3.500E+01 8.100E+01 8.936E-01 8.953E-01 6.915E-01 2.3754E-23 7.123595E-19 ----------------------------------------------------------------------------------------------------------------- GL=[2*[x+exp(-x)-1]/(x*x), where x = {lamda}*{irradiation time} and GEFF=-(alpha+LOG(SF)/dose)/(beta*dose). In the formula for GEFF, SF is surviving fraction as computed using the TLK model. The effects of lethal residual damage are included in the GEFF dose protraction factor but not GL1 or GL2. The estimates of the surviving fraction are SF1 = EXP{-dose*[alpha+(gl1*beta1+gl2*beta2)*dose]} and SF2 = EXP{-dose*(alpha+geff*beta*dose)}. QECK TABLE: Tumor control probability (TCP) estimates as a function of dose and dose rate. Cell kinetic parameters are: N(0)=F0*KAP*VOL=1.00000E+00, TCC=10.0000 h, Tpot=20.000 days. The *MAX* estimate is recommended (the other TCP estimates are mainly included in the table for diagnostic purposes). ===================================================================================================================== TSIM DOSE ---- EXPECTED NUMBER OF CELLS ---- ------ TUMOR CONTROL PROBABILITY (TCP) ------- SIM ID (day) (Gy) N(0)*S(D) N(t)*S(D) NSC(t) N(0)*S(D) N(t)*S(D) NSC(t) *MAX* --------------------------------------------------------------------------------------------------------------------- 1 4.000E+00 0.000E+00 1.0000E+00 1.0000E+00 1.0000E+00 3.6788E-01 3.6788E-01 3.6788E-01 3.6788E-01 2 1.517E+00 1.000E-01 9.8106E-01 9.8106E-01 9.8106E-01 3.7491E-01 3.7491E-01 3.7491E-01 3.7491E-01 3 2.043E+00 2.500E-01 9.5230E-01 9.5230E-01 9.5230E-01 3.8585E-01 3.8585E-01 3.8585E-01 3.8585E-01 4 2.087E+00 5.000E-01 9.0472E-01 9.0472E-01 9.0472E-01 4.0466E-01 4.0466E-01 4.0466E-01 4.0466E-01 5 2.174E+00 1.000E+00 8.1454E-01 8.1454E-01 8.1454E-01 4.4284E-01 4.4284E-01 4.4284E-01 4.4284E-01 6 2.260E+00 1.500E+00 7.3269E-01 7.3269E-01 7.3269E-01 4.8061E-01 4.8061E-01 4.8061E-01 4.8061E-01 7 2.347E+00 2.000E+00 6.5896E-01 6.5896E-01 6.5896E-01 5.1739E-01 5.1739E-01 5.1739E-01 5.1739E-01 8 2.521E+00 3.000E+00 5.3297E-01 5.3297E-01 5.3297E-01 5.8686E-01 5.8686E-01 5.8686E-01 5.8686E-01 9 2.694E+00 4.000E+00 4.3106E-01 4.3106E-01 4.3106E-01 6.4982E-01 6.4982E-01 6.4982E-01 6.4982E-01 10 2.868E+00 5.000E+00 3.4864E-01 3.4864E-01 3.4864E-01 7.0565E-01 7.0565E-01 7.0565E-01 7.0565E-01 11 3.042E+00 6.000E+00 2.8198E-01 2.8198E-01 2.8198E-01 7.5429E-01 7.5429E-01 7.5429E-01 7.5429E-01 12 3.215E+00 7.000E+00 2.2806E-01 2.2806E-01 2.2806E-01 7.9608E-01 7.9608E-01 7.9608E-01 7.9608E-01 13 3.389E+00 8.000E+00 1.8445E-01 1.8445E-01 1.8445E-01 8.3156E-01 8.3156E-01 8.3156E-01 8.3156E-01 14 3.562E+00 9.000E+00 1.4919E-01 1.4919E-01 1.4919E-01 8.6141E-01 8.6141E-01 8.6141E-01 8.6141E-01 15 3.736E+00 1.000E+01 1.2066E-01 1.2066E-01 1.2066E-01 8.8633E-01 8.8633E-01 8.8633E-01 8.8633E-01 16 4.170E+00 1.250E+01 7.0984E-02 7.0984E-02 7.0984E-02 9.3148E-01 9.3148E-01 9.3148E-01 9.3148E-01 17 4.604E+00 1.500E+01 4.1759E-02 4.1759E-02 4.1759E-02 9.5910E-01 9.5910E-01 9.5910E-01 9.5910E-01 18 5.038E+00 1.750E+01 2.4567E-02 2.4567E-02 2.4567E-02 9.7573E-01 9.7573E-01 9.7573E-01 9.7573E-01 19 5.472E+00 2.000E+01 1.4452E-02 1.4452E-02 1.4452E-02 9.8565E-01 9.8565E-01 9.8565E-01 9.8565E-01 20 6.340E+00 2.500E+01 5.0019E-03 5.0019E-03 5.0019E-03 9.9501E-01 9.9501E-01 9.9501E-01 9.9501E-01 21 7.208E+00 3.000E+01 1.7311E-03 1.7311E-03 1.7311E-03 9.9827E-01 9.9827E-01 9.9827E-01 9.9827E-01 22 8.076E+00 3.500E+01 5.9911E-04 5.9911E-04 5.9911E-04 9.9940E-01 9.9940E-01 9.9940E-01 9.9940E-01 23 4.000E+00 0.000E+00 1.0000E+00 1.0000E+00 1.0000E+00 3.6788E-01 3.6788E-01 3.6788E-01 3.6788E-01 24 1.512E+00 1.000E-01 9.8105E-01 9.8105E-01 9.8105E-01 3.7492E-01 3.7492E-01 3.7492E-01 3.7492E-01 25 2.031E+00 2.500E-01 9.5215E-01 9.5215E-01 9.5215E-01 3.8591E-01 3.8591E-01 3.8591E-01 3.8591E-01 26 2.061E+00 5.000E-01 9.0393E-01 9.0393E-01 9.0393E-01 4.0498E-01 4.0498E-01 4.0498E-01 4.0498E-01 27 2.123E+00 1.000E+00 8.1131E-01 8.1131E-01 8.1131E-01 4.4428E-01 4.4428E-01 4.4428E-01 4.4428E-01 28 2.184E+00 1.500E+00 7.2661E-01 7.2661E-01 7.2661E-01 4.8354E-01 4.8354E-01 4.8354E-01 4.8354E-01 29 2.245E+00 2.000E+00 6.5033E-01 6.5033E-01 6.5033E-01 5.2187E-01 5.2187E-01 5.2187E-01 5.2187E-01 30 2.368E+00 3.000E+00 5.2072E-01 5.2072E-01 5.2072E-01 5.9409E-01 5.9409E-01 5.9409E-01 5.9409E-01 31 2.490E+00 4.000E+00 4.1690E-01 4.1690E-01 4.1690E-01 6.5909E-01 6.5909E-01 6.5909E-01 6.5909E-01 32 2.613E+00 5.000E+00 3.3377E-01 3.3377E-01 3.3377E-01 7.1622E-01 7.1622E-01 7.1622E-01 7.1622E-01 33 2.735E+00 6.000E+00 2.6722E-01 2.6722E-01 2.6722E-01 7.6551E-01 7.6551E-01 7.6551E-01 7.6551E-01 34 2.858E+00 7.000E+00 2.1394E-01 2.1394E-01 2.1394E-01 8.0740E-01 8.0740E-01 8.0740E-01 8.0740E-01 35 2.980E+00 8.000E+00 1.7128E-01 1.7128E-01 1.7128E-01 8.4259E-01 8.4259E-01 8.4259E-01 8.4259E-01 36 3.103E+00 9.000E+00 1.3713E-01 1.3713E-01 1.3713E-01 8.7186E-01 8.7186E-01 8.7186E-01 8.7186E-01 37 3.225E+00 1.000E+01 1.0979E-01 1.0979E-01 1.0979E-01 8.9603E-01 8.9603E-01 8.9603E-01 8.9603E-01 38 3.532E+00 1.250E+01 6.2964E-02 6.2964E-02 6.2964E-02 9.3898E-01 9.3898E-01 9.3898E-01 9.3898E-01 39 3.838E+00 1.500E+01 3.6111E-02 3.6111E-02 3.6111E-02 9.6453E-01 9.6453E-01 9.6453E-01 9.6453E-01 40 4.145E+00 1.750E+01 2.0710E-02 2.0710E-02 2.0710E-02 9.7950E-01 9.7950E-01 9.7950E-01 9.7950E-01 41 4.451E+00 2.000E+01 1.1878E-02 1.1878E-02 1.1878E-02 9.8819E-01 9.8819E-01 9.8819E-01 9.8819E-01 42 5.064E+00 2.500E+01 3.9069E-03 3.9069E-03 3.9069E-03 9.9610E-01 9.9610E-01 9.9610E-01 9.9610E-01 43 5.676E+00 3.000E+01 1.2851E-03 1.2851E-03 1.2851E-03 9.9872E-01 9.9872E-01 9.9872E-01 9.9872E-01 44 6.289E+00 3.500E+01 4.2269E-04 4.2269E-04 4.2269E-04 9.9958E-01 9.9958E-01 9.9958E-01 9.9958E-01 45 4.000E+00 0.000E+00 1.0000E+00 1.0000E+00 1.0000E+00 3.6788E-01 3.6788E-01 3.6788E-01 3.6788E-01 46 1.506E+00 1.000E-01 9.8103E-01 9.8103E-01 9.8103E-01 3.7492E-01 3.7492E-01 3.7492E-01 3.7492E-01 47 2.015E+00 2.500E-01 9.5195E-01 9.5195E-01 9.5195E-01 3.8599E-01 3.8599E-01 3.8599E-01 3.8599E-01 48 2.029E+00 5.000E-01 9.0266E-01 9.0266E-01 9.0266E-01 4.0549E-01 4.0549E-01 4.0549E-01 4.0549E-01 49 2.059E+00 1.000E+00 8.0509E-01 8.0509E-01 8.0509E-01 4.4705E-01 4.4705E-01 4.4705E-01 4.4705E-01 50 2.088E+00 1.500E+00 7.1325E-01 7.1325E-01 7.1325E-01 4.9005E-01 4.9005E-01 4.9005E-01 4.9005E-01 51 2.117E+00 2.000E+00 6.2950E-01 6.2950E-01 6.2950E-01 5.3286E-01 5.3286E-01 5.3286E-01 5.3286E-01 52 2.176E+00 3.000E+00 4.8771E-01 4.8771E-01 4.8771E-01 6.1403E-01 6.1403E-01 6.1403E-01 6.1403E-01 53 2.235E+00 4.000E+00 3.7676E-01 3.7676E-01 3.7676E-01 6.8608E-01 6.8608E-01 6.8608E-01 6.8608E-01 54 2.293E+00 5.000E+00 2.9078E-01 2.9078E-01 2.9078E-01 7.4768E-01 7.4768E-01 7.4768E-01 7.4768E-01 55 2.352E+00 6.000E+00 2.2436E-01 2.2436E-01 2.2436E-01 7.9903E-01 7.9903E-01 7.9903E-01 7.9903E-01 56 2.411E+00 7.000E+00 1.7310E-01 1.7310E-01 1.7310E-01 8.4106E-01 8.4106E-01 8.4106E-01 8.4106E-01 57 2.469E+00 8.000E+00 1.3354E-01 1.3354E-01 1.3354E-01 8.7499E-01 8.7499E-01 8.7499E-01 8.7499E-01 58 2.528E+00 9.000E+00 1.0303E-01 1.0303E-01 1.0303E-01 9.0210E-01 9.0210E-01 9.0210E-01 9.0210E-01 59 2.587E+00 1.000E+01 7.9483E-02 7.9483E-02 7.9483E-02 9.2359E-01 9.2359E-01 9.2359E-01 9.2359E-01 60 2.734E+00 1.250E+01 4.1551E-02 4.1551E-02 4.1551E-02 9.5930E-01 9.5930E-01 9.5930E-01 9.5930E-01 61 2.880E+00 1.500E+01 2.1722E-02 2.1722E-02 2.1722E-02 9.7851E-01 9.7851E-01 9.7851E-01 9.7851E-01 62 3.027E+00 1.750E+01 1.1356E-02 1.1356E-02 1.1356E-02 9.8871E-01 9.8871E-01 9.8871E-01 9.8871E-01 63 3.174E+00 2.000E+01 5.9364E-03 5.9364E-03 5.9364E-03 9.9408E-01 9.9408E-01 9.9408E-01 9.9408E-01 64 3.467E+00 2.500E+01 1.6224E-03 1.6224E-03 1.6224E-03 9.9838E-01 9.9838E-01 9.9838E-01 9.9838E-01 65 3.761E+00 3.000E+01 4.4337E-04 4.4337E-04 4.4337E-04 9.9956E-01 9.9956E-01 9.9956E-01 9.9956E-01 66 4.054E+00 3.500E+01 1.2117E-04 1.2117E-04 1.2117E-04 9.9988E-01 9.9988E-01 9.9988E-01 9.9988E-01 67 4.000E+00 0.000E+00 1.0000E+00 1.0000E+00 1.0000E+00 3.6788E-01 3.6788E-01 3.6788E-01 3.6788E-01 68 2.000E+00 1.000E-01 9.8102E-01 9.8102E-01 9.8102E-01 3.7493E-01 3.7493E-01 3.7493E-01 3.7493E-01 69 2.000E+00 2.500E-01 9.5174E-01 9.5174E-01 9.5174E-01 3.8607E-01 3.8607E-01 3.8607E-01 3.8607E-01 70 2.000E+00 5.000E-01 9.0115E-01 9.0115E-01 9.0115E-01 4.0610E-01 4.0610E-01 4.0610E-01 4.0610E-01 71 2.001E+00 1.000E+00 7.9566E-01 7.9566E-01 7.9566E-01 4.5128E-01 4.5128E-01 4.5128E-01 4.5128E-01 72 2.001E+00 1.500E+00 6.8859E-01 6.8859E-01 6.8859E-01 5.0228E-01 5.0228E-01 5.0228E-01 5.0228E-01 73 2.001E+00 2.000E+00 5.8432E-01 5.8432E-01 5.8432E-01 5.5748E-01 5.5748E-01 5.5748E-01 5.5748E-01 74 2.002E+00 3.000E+00 3.9722E-01 3.9722E-01 3.9722E-01 6.7219E-01 6.7219E-01 6.7219E-01 6.7219E-01 75 2.002E+00 4.000E+00 2.5065E-01 2.5065E-01 2.5065E-01 7.7830E-01 7.7830E-01 7.7830E-01 7.7830E-01 76 2.003E+00 5.000E+00 1.4720E-01 1.4720E-01 1.4720E-01 8.6313E-01 8.6313E-01 8.6313E-01 8.6313E-01 77 2.003E+00 6.000E+00 8.0653E-02 8.0653E-02 8.0653E-02 9.2251E-01 9.2251E-01 9.2251E-01 9.2251E-01 78 2.004E+00 7.000E+00 4.1333E-02 4.1333E-02 4.1333E-02 9.5951E-01 9.5951E-01 9.5951E-01 9.5951E-01 79 2.004E+00 8.000E+00 1.9857E-02 1.9857E-02 1.9857E-02 9.8034E-01 9.8034E-01 9.8034E-01 9.8034E-01 80 2.005E+00 9.000E+00 8.9628E-03 8.9628E-03 8.9628E-03 9.9108E-01 9.9108E-01 9.9108E-01 9.9108E-01 81 2.005E+00 1.000E+01 3.8090E-03 3.8090E-03 3.8090E-03 9.9620E-01 9.9620E-01 9.9620E-01 9.9620E-01 82 2.006E+00 1.250E+01 3.4908E-04 3.4908E-04 3.4908E-04 9.9965E-01 9.9965E-01 9.9965E-01 9.9965E-01 83 2.008E+00 1.500E+01 2.2895E-05 2.2895E-05 2.2895E-05 9.9998E-01 9.9998E-01 9.9998E-01 9.9998E-01 84 2.009E+00 1.750E+01 1.1037E-06 1.1037E-06 1.1037E-06 1.0000E+00 1.0000E+00 1.0000E+00 1.0000E+00 85 2.010E+00 2.000E+01 4.0062E-08 4.0062E-08 4.0062E-08 1.0000E+00 1.0000E+00 1.0000E+00 1.0000E+00 86 2.013E+00 2.500E+01 2.4553E-11 2.4553E-11 2.4553E-11 1.0000E+00 1.0000E+00 1.0000E+00 1.0000E+00 87 2.015E+00 3.000E+01 6.1420E-15 6.1420E-15 6.1420E-15 1.0000E+00 1.0000E+00 1.0000E+00 1.0000E+00 88 2.018E+00 3.500E+01 7.1236E-19 7.1236E-19 7.1236E-19 1.0000E+00 1.0000E+00 1.0000E+00 1.0000E+00 --------------------------------------------------------------------------------------------------------------------- NOTE: TCP={probability no cells survive}=EXP{-(expected number of surviving cells)}. TCP estimates are based on the expected number of surviving cells with and without corrections for repopulation effects. The *MAX* TCP is the peak (all time points after irradiation) estimate derived from NSC(t). RADX EXPOSURE SUMMARY ============================================================================== SCENARIO ----- DURATION ----- ------ DOSE (Gy) ----- -- DOSE RATE (Gy/h) -- NUMBER hours days Background Total Background Total* ------------------------------------------------------------------------------ 1 2.778E-13 1.157E-14 0.0000E+00 0.0000E+00 0.0000E+00 0.0000E+00 2 4.167E-01 1.736E-02 0.0000E+00 1.0000E-01 0.0000E+00 2.4000E-01 3 1.042E+00 4.340E-02 0.0000E+00 2.5000E-01 0.0000E+00 2.4000E-01 4 2.083E+00 8.681E-02 0.0000E+00 5.0000E-01 0.0000E+00 2.4000E-01 5 4.167E+00 1.736E-01 0.0000E+00 1.0000E+00 0.0000E+00 2.4000E-01 6 6.250E+00 2.604E-01 0.0000E+00 1.5000E+00 0.0000E+00 2.4000E-01 7 8.333E+00 3.472E-01 0.0000E+00 2.0000E+00 0.0000E+00 2.4000E-01 8 1.250E+01 5.208E-01 0.0000E+00 3.0000E+00 0.0000E+00 2.4000E-01 9 1.667E+01 6.944E-01 0.0000E+00 4.0000E+00 0.0000E+00 2.4000E-01 10 2.083E+01 8.681E-01 0.0000E+00 5.0000E+00 0.0000E+00 2.4000E-01 11 2.500E+01 1.042E+00 0.0000E+00 6.0000E+00 0.0000E+00 2.4000E-01 12 2.917E+01 1.215E+00 0.0000E+00 7.0000E+00 0.0000E+00 2.4000E-01 13 3.333E+01 1.389E+00 0.0000E+00 8.0000E+00 0.0000E+00 2.4000E-01 14 3.750E+01 1.562E+00 0.0000E+00 9.0000E+00 0.0000E+00 2.4000E-01 15 4.167E+01 1.736E+00 0.0000E+00 1.0000E+01 0.0000E+00 2.4000E-01 16 5.208E+01 2.170E+00 0.0000E+00 1.2500E+01 0.0000E+00 2.4000E-01 17 6.250E+01 2.604E+00 0.0000E+00 1.5000E+01 0.0000E+00 2.4000E-01 18 7.292E+01 3.038E+00 0.0000E+00 1.7500E+01 0.0000E+00 2.4000E-01 19 8.333E+01 3.472E+00 0.0000E+00 2.0000E+01 0.0000E+00 2.4000E-01 20 1.042E+02 4.340E+00 0.0000E+00 2.5000E+01 0.0000E+00 2.4000E-01 21 1.250E+02 5.208E+00 0.0000E+00 3.0000E+01 0.0000E+00 2.4000E-01 22 1.458E+02 6.076E+00 0.0000E+00 3.5000E+01 0.0000E+00 2.4000E-01 23 2.778E-13 1.157E-14 0.0000E+00 0.0000E+00 0.0000E+00 0.0000E+00 24 2.941E-01 1.225E-02 0.0000E+00 1.0000E-01 0.0000E+00 3.4000E-01 25 7.353E-01 3.064E-02 0.0000E+00 2.5000E-01 0.0000E+00 3.4000E-01 26 1.471E+00 6.127E-02 0.0000E+00 5.0000E-01 0.0000E+00 3.4000E-01 27 2.941E+00 1.225E-01 0.0000E+00 1.0000E+00 0.0000E+00 3.4000E-01 28 4.412E+00 1.838E-01 0.0000E+00 1.5000E+00 0.0000E+00 3.4000E-01 29 5.882E+00 2.451E-01 0.0000E+00 2.0000E+00 0.0000E+00 3.4000E-01 30 8.824E+00 3.676E-01 0.0000E+00 3.0000E+00 0.0000E+00 3.4000E-01 31 1.176E+01 4.902E-01 0.0000E+00 4.0000E+00 0.0000E+00 3.4000E-01 32 1.471E+01 6.127E-01 0.0000E+00 5.0000E+00 0.0000E+00 3.4000E-01 33 1.765E+01 7.353E-01 0.0000E+00 6.0000E+00 0.0000E+00 3.4000E-01 34 2.059E+01 8.578E-01 0.0000E+00 7.0000E+00 0.0000E+00 3.4000E-01 35 2.353E+01 9.804E-01 0.0000E+00 8.0000E+00 0.0000E+00 3.4000E-01 36 2.647E+01 1.103E+00 0.0000E+00 9.0000E+00 0.0000E+00 3.4000E-01 37 2.941E+01 1.225E+00 0.0000E+00 1.0000E+01 0.0000E+00 3.4000E-01 38 3.676E+01 1.532E+00 0.0000E+00 1.2500E+01 0.0000E+00 3.4000E-01 39 4.412E+01 1.838E+00 0.0000E+00 1.5000E+01 0.0000E+00 3.4000E-01 40 5.147E+01 2.145E+00 0.0000E+00 1.7500E+01 0.0000E+00 3.4000E-01 41 5.882E+01 2.451E+00 0.0000E+00 2.0000E+01 0.0000E+00 3.4000E-01 42 7.353E+01 3.064E+00 0.0000E+00 2.5000E+01 0.0000E+00 3.4000E-01 43 8.824E+01 3.676E+00 0.0000E+00 3.0000E+01 0.0000E+00 3.4000E-01 44 1.029E+02 4.289E+00 0.0000E+00 3.5000E+01 0.0000E+00 3.4000E-01 45 2.778E-13 1.157E-14 0.0000E+00 0.0000E+00 0.0000E+00 0.0000E+00 46 1.408E-01 5.869E-03 0.0000E+00 1.0000E-01 0.0000E+00 7.1000E-01 47 3.521E-01 1.467E-02 0.0000E+00 2.5000E-01 0.0000E+00 7.1000E-01 48 7.042E-01 2.934E-02 0.0000E+00 5.0000E-01 0.0000E+00 7.1000E-01 49 1.408E+00 5.869E-02 0.0000E+00 1.0000E+00 0.0000E+00 7.1000E-01 50 2.113E+00 8.803E-02 0.0000E+00 1.5000E+00 0.0000E+00 7.1000E-01 51 2.817E+00 1.174E-01 0.0000E+00 2.0000E+00 0.0000E+00 7.1000E-01 52 4.225E+00 1.761E-01 0.0000E+00 3.0000E+00 0.0000E+00 7.1000E-01 53 5.634E+00 2.347E-01 0.0000E+00 4.0000E+00 0.0000E+00 7.1000E-01 54 7.042E+00 2.934E-01 0.0000E+00 5.0000E+00 0.0000E+00 7.1000E-01 55 8.451E+00 3.521E-01 0.0000E+00 6.0000E+00 0.0000E+00 7.1000E-01 56 9.859E+00 4.108E-01 0.0000E+00 7.0000E+00 0.0000E+00 7.1000E-01 57 1.127E+01 4.695E-01 0.0000E+00 8.0000E+00 0.0000E+00 7.1000E-01 58 1.268E+01 5.282E-01 0.0000E+00 9.0000E+00 0.0000E+00 7.1000E-01 59 1.408E+01 5.869E-01 0.0000E+00 1.0000E+01 0.0000E+00 7.1000E-01 60 1.761E+01 7.336E-01 0.0000E+00 1.2500E+01 0.0000E+00 7.1000E-01 61 2.113E+01 8.803E-01 0.0000E+00 1.5000E+01 0.0000E+00 7.1000E-01 62 2.465E+01 1.027E+00 0.0000E+00 1.7500E+01 0.0000E+00 7.1000E-01 63 2.817E+01 1.174E+00 0.0000E+00 2.0000E+01 0.0000E+00 7.1000E-01 64 3.521E+01 1.467E+00 0.0000E+00 2.5000E+01 0.0000E+00 7.1000E-01 65 4.225E+01 1.761E+00 0.0000E+00 3.0000E+01 0.0000E+00 7.1000E-01 66 4.930E+01 2.054E+00 0.0000E+00 3.5000E+01 0.0000E+00 7.1000E-01 67 2.778E-13 1.157E-14 0.0000E+00 0.0000E+00 0.0000E+00 0.0000E+00 68 1.235E-03 5.144E-05 0.0000E+00 1.0000E-01 0.0000E+00 8.1000E+01 69 3.086E-03 1.286E-04 0.0000E+00 2.5000E-01 0.0000E+00 8.1000E+01 70 6.173E-03 2.572E-04 0.0000E+00 5.0000E-01 0.0000E+00 8.1000E+01 71 1.235E-02 5.144E-04 0.0000E+00 1.0000E+00 0.0000E+00 8.1000E+01 72 1.852E-02 7.716E-04 0.0000E+00 1.5000E+00 0.0000E+00 8.1000E+01 73 2.469E-02 1.029E-03 0.0000E+00 2.0000E+00 0.0000E+00 8.1000E+01 74 3.704E-02 1.543E-03 0.0000E+00 3.0000E+00 0.0000E+00 8.1000E+01 75 4.938E-02 2.058E-03 0.0000E+00 4.0000E+00 0.0000E+00 8.1000E+01 76 6.173E-02 2.572E-03 0.0000E+00 5.0000E+00 0.0000E+00 8.1000E+01 77 7.407E-02 3.086E-03 0.0000E+00 6.0000E+00 0.0000E+00 8.1000E+01 78 8.642E-02 3.601E-03 0.0000E+00 7.0000E+00 0.0000E+00 8.1000E+01 79 9.877E-02 4.115E-03 0.0000E+00 8.0000E+00 0.0000E+00 8.1000E+01 80 1.111E-01 4.630E-03 0.0000E+00 9.0000E+00 0.0000E+00 8.1000E+01 81 1.235E-01 5.144E-03 0.0000E+00 1.0000E+01 0.0000E+00 8.1000E+01 82 1.543E-01 6.430E-03 0.0000E+00 1.2500E+01 0.0000E+00 8.1000E+01 83 1.852E-01 7.716E-03 0.0000E+00 1.5000E+01 0.0000E+00 8.1000E+01 84 2.160E-01 9.002E-03 0.0000E+00 1.7500E+01 0.0000E+00 8.1000E+01 85 2.469E-01 1.029E-02 0.0000E+00 2.0000E+01 0.0000E+00 8.1000E+01 86 3.086E-01 1.286E-02 0.0000E+00 2.5000E+01 0.0000E+00 8.1000E+01 87 3.704E-01 1.543E-02 0.0000E+00 3.0000E+01 0.0000E+00 8.1000E+01 88 4.321E-01 1.800E-02 0.0000E+00 3.5000E+01 0.0000E+00 8.1000E+01 ------------------------------------------------------------------------------ * Dose rate is the delivered dose divided by the duration of the exposure scenario. Total VC execution time (min): 1.64000E-02 VC 2.00G 05-JUL-2003 20-JUL-2003 04:00:04 PM