VC 2.00G 05-JUL-2003 20-JUL-2003 12:14:05 AM by RD Stewart (trebor@purdue.edu) PROGRAM FILE INPUT/OUTPUT AND RUN-TIME OPTIONS: ================================================================================ CMD: c:\vc\samples\bin\vc.exe c:\vc2\archive\ag1522\rmr\ag1522.inp FNI: C:\VC2\archive\ag1522\rmr\ag1522.inp FNO: C:\VC2\archive\ag1522\rmr\ag1522.out RADX: C:\VC2\archive\ag1522\rmr\ag1522.radx (88 exposures) -------------------------------------------------------------------------------- QECK TABLE: Cell and tissue kinetic parameters. ================================================================================ Duration of cell cycle (TCC): 10.00000 h Potential doubling time (Tpot): 480.00000 h (= 20.000 days) Cell birth rate (AX): 1.6636E+00 cell/day (= LOG(2)/TCC) Cell death rate (BX): 1.6289E+00 cell/day [=AX-LOG(2)/TPOT] Net cell birth rate (AX-BX): 3.4657E-02 cell/day Initial Number of Cells: non-dividing: 1.00000E+00 (100.000% = 1-GF) dividing: 0.00000E+00 ( 0.000% = GF) total: 1.00000E+00 (100.000% total) Life Support Capacity of System: Initial system capacity utilization: 0.000000% (=F0) Peak cell density (cells/cm^3): 1.00000E+38 (=KAP) Tissue volume (cm^3): 1.00000E+00 (=VOL) Maximum number of cells (cells): 1.00000E+38 (=KAP*VOL) -------------------------------------------------------------------------------- RMRM TABLE: Summary of RMR parameters and related (derived) quantities. ======================================================================== G0/G1 DNA CONTENT: 5667.000 Mbp/cell = 3.482938E+12 Da/cell ENDOGENOUS DAMAGE: per (h-Da) per (h-Mbp) per (h-cell) DSB = 0.00000E+00 0.00000E+00 0.00000E+00 DAMAGE FORMATION: per (Gy-Da) per (Gy-Mbp) per (Gy-cell) DSB = 7.17785E-12 4.41151E-03 25.000000 DAMAGE REPAIR/MISREPAIR: A0= 0.000000E+00 (=0.000%) (1-A0)*PHI= 7.500386E-03 (=0.750%) (1-A0)*(1-PHI)= 9.924996E-01 (=99.250%) RHT= 0.864888 h (=51.89 minute) LAM= 8.0143011E-01 (1/h) BMR= 4.3973090E-04 (1/h) LAM/BMR= 1.8225467E+03 GAM= 0.250 ***** EQUIVALENT LQ MODEL PARAMETERS ***** alpha = 0.187510 (1/Gy) beta = 0.041580 (1/Gy^2) alpha/beta = 4.509633 (Gy) ------------------------------------------------------------------------ NOTE: 1 bp = 614.6 Da (amu) = 1.0205E-09 pg DFAR TABLE: Cell survival as a function of dose and dose rate (FRDL=100.0%). ====================================================================================================== --- Duration (h) --- Dose Dose Rate ---- LETHAL DAMAGE PER CELL ---- SIM ID Exposure Sim (Gy) (Gy/h) Mutations Residual Total SF(dose) ------------------------------------------------------------------------------------------------------ 1 2.778E-13 9.600E+01 0.000E+00 0.000E+00 0.000E+00 0.000E+00 0.0000E+00 1.000000E+00 2 4.167E-01 3.642E+01 1.000E-01 2.400E-01 1.912E-02 2.339E-11 1.9124E-02 9.810579E-01 3 1.042E+00 3.704E+01 2.500E-01 2.400E-01 4.888E-02 0.000E+00 4.8878E-02 9.522974E-01 4 2.083E+00 3.808E+01 5.000E-01 2.400E-01 1.001E-01 0.000E+00 1.0013E-01 9.047187E-01 5 4.167E+00 4.017E+01 1.000E+00 2.400E-01 2.051E-01 0.000E+00 2.0513E-01 8.145441E-01 6 6.250E+00 4.225E+01 1.500E+00 2.400E-01 3.110E-01 0.000E+00 3.1103E-01 7.326949E-01 7 8.333E+00 4.433E+01 2.000E+00 2.400E-01 4.171E-01 0.000E+00 4.1709E-01 6.589598E-01 8 1.250E+01 4.850E+01 3.000E+00 2.400E-01 6.293E-01 0.000E+00 6.2929E-01 5.329675E-01 9 1.667E+01 5.267E+01 4.000E+00 2.400E-01 8.415E-01 0.000E+00 8.4151E-01 4.310613E-01 10 2.083E+01 5.683E+01 5.000E+00 2.400E-01 1.054E+00 0.000E+00 1.0537E+00 3.486399E-01 11 2.500E+01 6.100E+01 6.000E+00 2.400E-01 1.266E+00 0.000E+00 1.2659E+00 2.819780E-01 12 2.917E+01 6.517E+01 7.000E+00 2.400E-01 1.478E+00 0.000E+00 1.4781E+00 2.280623E-01 13 3.333E+01 6.933E+01 8.000E+00 2.400E-01 1.690E+00 0.000E+00 1.6903E+00 1.844555E-01 14 3.750E+01 7.350E+01 9.000E+00 2.400E-01 1.903E+00 0.000E+00 1.9026E+00 1.491866E-01 15 4.167E+01 7.767E+01 1.000E+01 2.400E-01 2.115E+00 0.000E+00 2.1148E+00 1.206613E-01 16 5.208E+01 8.808E+01 1.250E+01 2.400E-01 2.645E+00 0.000E+00 2.6453E+00 7.098446E-02 17 6.250E+01 9.850E+01 1.500E+01 2.400E-01 3.176E+00 0.000E+00 3.1758E+00 4.175982E-02 18 7.292E+01 1.089E+02 1.750E+01 2.400E-01 3.706E+00 0.000E+00 3.7063E+00 2.456711E-02 19 8.333E+01 1.193E+02 2.000E+01 2.400E-01 4.237E+00 0.000E+00 4.2369E+00 1.445271E-02 20 1.042E+02 1.402E+02 2.500E+01 2.400E-01 5.298E+00 0.000E+00 5.2979E+00 5.001959E-03 21 1.250E+02 1.610E+02 3.000E+01 2.400E-01 6.359E+00 0.000E+00 6.3590E+00 1.731135E-03 22 1.458E+02 1.818E+02 3.500E+01 2.400E-01 7.420E+00 0.000E+00 7.4200E+00 5.991308E-04 23 2.778E-13 9.600E+01 0.000E+00 0.000E+00 0.000E+00 0.000E+00 0.0000E+00 1.000000E+00 24 2.941E-01 3.629E+01 1.000E-01 3.400E-01 1.914E-02 2.756E-11 1.9136E-02 9.810463E-01 25 7.353E-01 3.674E+01 2.500E-01 3.400E-01 4.903E-02 0.000E+00 4.9028E-02 9.521541E-01 26 1.471E+00 3.747E+01 5.000E-01 3.400E-01 1.010E-01 0.000E+00 1.0101E-01 9.039276E-01 27 2.941E+00 3.894E+01 1.000E+00 3.400E-01 2.091E-01 0.000E+00 2.0911E-01 8.113089E-01 28 4.412E+00 4.041E+01 1.500E+00 3.400E-01 3.194E-01 0.000E+00 3.1936E-01 7.266138E-01 29 5.882E+00 4.188E+01 2.000E+00 3.400E-01 4.303E-01 0.000E+00 4.3027E-01 6.503350E-01 30 8.824E+00 4.482E+01 3.000E+00 3.400E-01 6.525E-01 0.000E+00 6.5254E-01 5.207217E-01 31 1.176E+01 4.776E+01 4.000E+00 3.400E-01 8.749E-01 0.000E+00 8.7491E-01 4.168979E-01 32 1.471E+01 5.071E+01 5.000E+00 3.400E-01 1.097E+00 0.000E+00 1.0973E+00 3.337719E-01 33 1.765E+01 5.365E+01 6.000E+00 3.400E-01 1.320E+00 0.000E+00 1.3197E+00 2.672202E-01 34 2.059E+01 5.659E+01 7.000E+00 3.400E-01 1.542E+00 0.000E+00 1.5421E+00 2.139385E-01 35 2.353E+01 5.953E+01 8.000E+00 3.400E-01 1.764E+00 0.000E+00 1.7645E+00 1.712807E-01 36 2.647E+01 6.247E+01 9.000E+00 3.400E-01 1.987E+00 0.000E+00 1.9868E+00 1.371286E-01 37 2.941E+01 6.541E+01 1.000E+01 3.400E-01 2.209E+00 0.000E+00 2.2092E+00 1.097861E-01 38 3.676E+01 7.276E+01 1.250E+01 3.400E-01 2.765E+00 0.000E+00 2.7652E+00 6.296460E-02 39 4.412E+01 8.012E+01 1.500E+01 3.400E-01 3.321E+00 0.000E+00 3.3211E+00 3.611148E-02 40 5.147E+01 8.747E+01 1.750E+01 3.400E-01 3.877E+00 0.000E+00 3.8771E+00 2.071067E-02 41 5.882E+01 9.482E+01 2.000E+01 3.400E-01 4.433E+00 0.000E+00 4.4331E+00 1.187799E-02 42 7.353E+01 1.095E+02 2.500E+01 3.400E-01 5.545E+00 0.000E+00 5.5450E+00 3.906978E-03 43 8.824E+01 1.242E+02 3.000E+01 3.400E-01 6.657E+00 0.000E+00 6.6569E+00 1.285105E-03 44 1.029E+02 1.389E+02 3.500E+01 3.400E-01 7.769E+00 0.000E+00 7.7688E+00 4.227041E-04 45 2.778E-13 9.600E+01 0.000E+00 0.000E+00 0.000E+00 0.000E+00 0.0000E+00 1.000000E+00 46 1.408E-01 3.614E+01 1.000E-01 7.100E-01 1.915E-02 3.171E-11 1.9151E-02 9.810310E-01 47 3.521E-01 3.635E+01 2.500E-01 7.100E-01 4.924E-02 0.000E+00 4.9243E-02 9.519499E-01 48 7.042E-01 3.670E+01 5.000E-01 7.100E-01 1.024E-01 0.000E+00 1.0241E-01 9.026633E-01 49 1.408E+00 3.741E+01 1.000E+00 7.100E-01 2.168E-01 0.000E+00 2.1680E-01 8.050889E-01 50 2.113E+00 3.811E+01 1.500E+00 7.100E-01 3.379E-01 0.000E+00 3.3793E-01 7.132475E-01 51 2.817E+00 3.882E+01 2.000E+00 7.100E-01 4.628E-01 0.000E+00 4.6282E-01 6.295028E-01 52 4.225E+00 4.023E+01 3.000E+00 7.100E-01 7.180E-01 0.000E+00 7.1804E-01 4.877051E-01 53 5.634E+00 4.163E+01 4.000E+00 7.100E-01 9.762E-01 0.000E+00 9.7616E-01 3.767556E-01 54 7.042E+00 4.304E+01 5.000E+00 7.100E-01 1.235E+00 0.000E+00 1.2352E+00 2.907812E-01 55 8.451E+00 4.445E+01 6.000E+00 7.100E-01 1.494E+00 0.000E+00 1.4945E+00 2.243615E-01 56 9.859E+00 4.586E+01 7.000E+00 7.100E-01 1.754E+00 0.000E+00 1.7539E+00 1.730977E-01 57 1.127E+01 4.727E+01 8.000E+00 7.100E-01 2.013E+00 0.000E+00 2.0133E+00 1.335432E-01 58 1.268E+01 4.868E+01 9.000E+00 7.100E-01 2.273E+00 0.000E+00 2.2728E+00 1.030264E-01 59 1.408E+01 5.008E+01 1.000E+01 7.100E-01 2.532E+00 0.000E+00 2.5322E+00 7.948292E-02 60 1.761E+01 5.361E+01 1.250E+01 7.100E-01 3.181E+00 0.000E+00 3.1808E+00 4.155145E-02 61 2.113E+01 5.713E+01 1.500E+01 7.100E-01 3.829E+00 0.000E+00 3.8294E+00 2.172192E-02 62 2.465E+01 6.065E+01 1.750E+01 7.100E-01 4.478E+00 0.000E+00 4.4780E+00 1.135561E-02 63 2.817E+01 6.417E+01 2.000E+01 7.100E-01 5.127E+00 0.000E+00 5.1267E+00 5.936390E-03 64 3.521E+01 7.121E+01 2.500E+01 7.100E-01 6.424E+00 0.000E+00 6.4239E+00 1.622358E-03 65 4.225E+01 7.825E+01 3.000E+01 7.100E-01 7.721E+00 0.000E+00 7.7211E+00 4.433746E-04 66 4.930E+01 8.530E+01 3.500E+01 7.100E-01 9.018E+00 0.000E+00 9.0183E+00 1.211700E-04 67 2.778E-13 9.600E+01 0.000E+00 0.000E+00 0.000E+00 0.000E+00 0.0000E+00 1.000000E+00 68 1.235E-03 3.600E+01 1.000E-01 8.100E+01 1.917E-02 3.443E-11 1.9166E-02 9.810163E-01 69 3.086E-03 3.600E+01 2.500E-01 8.100E+01 4.947E-02 0.000E+00 4.9468E-02 9.517355E-01 70 6.173E-03 3.601E+01 5.000E-01 8.100E+01 1.041E-01 0.000E+00 1.0409E-01 9.011483E-01 71 1.235E-02 3.601E+01 1.000E+00 8.100E+01 2.286E-01 0.000E+00 2.2858E-01 7.956641E-01 72 1.852E-02 3.602E+01 1.500E+00 8.100E+01 3.731E-01 0.000E+00 3.7310E-01 6.885940E-01 73 2.469E-02 3.602E+01 2.000E+00 8.100E+01 5.373E-01 0.000E+00 5.3730E-01 5.843265E-01 74 3.704E-02 3.604E+01 3.000E+00 8.100E+01 9.233E-01 0.000E+00 9.2326E-01 3.972230E-01 75 4.938E-02 3.605E+01 4.000E+00 8.100E+01 1.384E+00 7.409E-11 1.3837E+00 2.506493E-01 76 6.173E-02 3.606E+01 5.000E+00 8.100E+01 1.916E+00 5.446E-11 1.9160E+00 1.471969E-01 77 7.407E-02 3.607E+01 6.000E+00 8.100E+01 2.518E+00 4.318E-11 2.5176E+00 8.065419E-02 78 8.642E-02 3.609E+01 7.000E+00 8.100E+01 3.186E+00 2.342E-11 3.1861E+00 4.133332E-02 79 9.877E-02 3.610E+01 8.000E+00 8.100E+01 3.919E+00 0.000E+00 3.9192E+00 1.985740E-02 80 1.111E-01 3.611E+01 9.000E+00 8.100E+01 4.715E+00 0.000E+00 4.7146E+00 8.963018E-03 81 1.235E-01 3.612E+01 1.000E+01 8.100E+01 5.570E+00 0.000E+00 5.5704E+00 3.809050E-03 82 1.543E-01 3.615E+01 1.250E+01 8.100E+01 7.960E+00 2.369E-10 7.9602E+00 3.490875E-04 83 1.852E-01 3.619E+01 1.500E+01 8.100E+01 1.068E+01 2.199E-10 1.0685E+01 2.289534E-05 84 2.160E-01 3.622E+01 1.750E+01 8.100E+01 1.372E+01 2.127E-10 1.3717E+01 1.103692E-06 85 2.469E-01 3.625E+01 2.000E+01 8.100E+01 1.703E+01 0.000E+00 1.7033E+01 4.006195E-08 86 3.086E-01 3.631E+01 2.500E+01 8.100E+01 2.443E+01 6.105E-11 2.4430E+01 2.455237E-11 87 3.704E-01 3.637E+01 3.000E+01 8.100E+01 3.272E+01 4.657E-11 3.2724E+01 6.141274E-15 88 4.321E-01 3.643E+01 3.500E+01 8.100E+01 4.179E+01 3.544E-10 4.1786E+01 7.122113E-19 ------------------------------------------------------------------------------------------------------ NOTE: SF=EXP{-(lethal residual damage + lethal mutations)}. QECK TABLE: Cell survival, corrected for repopulation effects, as a function of dose and dose rate. Cell kinetic parameters are: N(0)=F0*KAP*VOL=1.00000E+00, TCC=10.0000 h, Tpot=20.000 days. ===================================================================================================================== TSIM DOSE DOSE RATE - SURVIVING FRACTION - --------- EXPECTED NUMBER OF CELLS ----------- SIM ID (day) (Gy) (Gy/h) no repop repop N(t)/N(0) N(0)*S(D) N(t)*S(D) NSC(t) --------------------------------------------------------------------------------------------------------------------- 1 4.000E+00 0.000E+00 0.000E+00 1.0000E+00 1.0000E+00 1.0000E+00 1.0000E+00 1.0000E+00 1.0000E+00 2 1.517E+00 1.000E-01 2.400E-01 9.8106E-01 9.8106E-01 1.0000E+00 9.8106E-01 9.8106E-01 9.8106E-01 3 1.543E+00 2.500E-01 2.400E-01 9.5230E-01 9.5230E-01 1.0000E+00 9.5230E-01 9.5230E-01 9.5230E-01 4 1.587E+00 5.000E-01 2.400E-01 9.0472E-01 9.0472E-01 1.0000E+00 9.0472E-01 9.0472E-01 9.0472E-01 5 1.674E+00 1.000E+00 2.400E-01 8.1454E-01 8.1454E-01 1.0000E+00 8.1454E-01 8.1454E-01 8.1454E-01 6 1.760E+00 1.500E+00 2.400E-01 7.3269E-01 7.3269E-01 1.0000E+00 7.3269E-01 7.3269E-01 7.3269E-01 7 1.847E+00 2.000E+00 2.400E-01 6.5896E-01 6.5896E-01 1.0000E+00 6.5896E-01 6.5896E-01 6.5896E-01 8 2.021E+00 3.000E+00 2.400E-01 5.3297E-01 5.3297E-01 1.0000E+00 5.3297E-01 5.3297E-01 5.3297E-01 9 2.194E+00 4.000E+00 2.400E-01 4.3106E-01 4.3106E-01 1.0000E+00 4.3106E-01 4.3106E-01 4.3106E-01 10 2.368E+00 5.000E+00 2.400E-01 3.4864E-01 3.4864E-01 1.0000E+00 3.4864E-01 3.4864E-01 3.4864E-01 11 2.542E+00 6.000E+00 2.400E-01 2.8198E-01 2.8198E-01 1.0000E+00 2.8198E-01 2.8198E-01 2.8198E-01 12 2.715E+00 7.000E+00 2.400E-01 2.2806E-01 2.2806E-01 1.0000E+00 2.2806E-01 2.2806E-01 2.2806E-01 13 2.889E+00 8.000E+00 2.400E-01 1.8446E-01 1.8446E-01 1.0000E+00 1.8446E-01 1.8446E-01 1.8446E-01 14 3.062E+00 9.000E+00 2.400E-01 1.4919E-01 1.4919E-01 1.0000E+00 1.4919E-01 1.4919E-01 1.4919E-01 15 3.236E+00 1.000E+01 2.400E-01 1.2066E-01 1.2066E-01 1.0000E+00 1.2066E-01 1.2066E-01 1.2066E-01 16 3.670E+00 1.250E+01 2.400E-01 7.0984E-02 7.0984E-02 1.0000E+00 7.0984E-02 7.0984E-02 7.0984E-02 17 4.104E+00 1.500E+01 2.400E-01 4.1760E-02 4.1760E-02 1.0000E+00 4.1760E-02 4.1760E-02 4.1760E-02 18 4.538E+00 1.750E+01 2.400E-01 2.4567E-02 2.4567E-02 1.0000E+00 2.4567E-02 2.4567E-02 2.4567E-02 19 4.972E+00 2.000E+01 2.400E-01 1.4453E-02 1.4453E-02 1.0000E+00 1.4453E-02 1.4453E-02 1.4453E-02 20 5.840E+00 2.500E+01 2.400E-01 5.0020E-03 5.0020E-03 1.0000E+00 5.0020E-03 5.0020E-03 5.0020E-03 21 6.708E+00 3.000E+01 2.400E-01 1.7311E-03 1.7311E-03 1.0000E+00 1.7311E-03 1.7311E-03 1.7311E-03 22 7.576E+00 3.500E+01 2.400E-01 5.9913E-04 5.9913E-04 1.0000E+00 5.9913E-04 5.9913E-04 5.9913E-04 23 4.000E+00 0.000E+00 0.000E+00 1.0000E+00 1.0000E+00 1.0000E+00 1.0000E+00 1.0000E+00 1.0000E+00 24 1.512E+00 1.000E-01 3.400E-01 9.8105E-01 9.8105E-01 1.0000E+00 9.8105E-01 9.8105E-01 9.8105E-01 25 1.531E+00 2.500E-01 3.400E-01 9.5215E-01 9.5215E-01 1.0000E+00 9.5215E-01 9.5215E-01 9.5215E-01 26 1.561E+00 5.000E-01 3.400E-01 9.0393E-01 9.0393E-01 1.0000E+00 9.0393E-01 9.0393E-01 9.0393E-01 27 1.623E+00 1.000E+00 3.400E-01 8.1131E-01 8.1131E-01 1.0000E+00 8.1131E-01 8.1131E-01 8.1131E-01 28 1.684E+00 1.500E+00 3.400E-01 7.2661E-01 7.2661E-01 1.0000E+00 7.2661E-01 7.2661E-01 7.2661E-01 29 1.745E+00 2.000E+00 3.400E-01 6.5034E-01 6.5034E-01 1.0000E+00 6.5034E-01 6.5034E-01 6.5034E-01 30 1.868E+00 3.000E+00 3.400E-01 5.2072E-01 5.2072E-01 1.0000E+00 5.2072E-01 5.2072E-01 5.2072E-01 31 1.990E+00 4.000E+00 3.400E-01 4.1690E-01 4.1690E-01 1.0000E+00 4.1690E-01 4.1690E-01 4.1690E-01 32 2.113E+00 5.000E+00 3.400E-01 3.3377E-01 3.3377E-01 1.0000E+00 3.3377E-01 3.3377E-01 3.3377E-01 33 2.235E+00 6.000E+00 3.400E-01 2.6722E-01 2.6722E-01 1.0000E+00 2.6722E-01 2.6722E-01 2.6722E-01 34 2.358E+00 7.000E+00 3.400E-01 2.1394E-01 2.1394E-01 1.0000E+00 2.1394E-01 2.1394E-01 2.1394E-01 35 2.480E+00 8.000E+00 3.400E-01 1.7128E-01 1.7128E-01 1.0000E+00 1.7128E-01 1.7128E-01 1.7128E-01 36 2.603E+00 9.000E+00 3.400E-01 1.3713E-01 1.3713E-01 1.0000E+00 1.3713E-01 1.3713E-01 1.3713E-01 37 2.725E+00 1.000E+01 3.400E-01 1.0979E-01 1.0979E-01 1.0000E+00 1.0979E-01 1.0979E-01 1.0979E-01 38 3.032E+00 1.250E+01 3.400E-01 6.2965E-02 6.2965E-02 1.0000E+00 6.2965E-02 6.2965E-02 6.2965E-02 39 3.338E+00 1.500E+01 3.400E-01 3.6111E-02 3.6111E-02 1.0000E+00 3.6111E-02 3.6111E-02 3.6111E-02 40 3.645E+00 1.750E+01 3.400E-01 2.0711E-02 2.0711E-02 1.0000E+00 2.0711E-02 2.0711E-02 2.0711E-02 41 3.951E+00 2.000E+01 3.400E-01 1.1878E-02 1.1878E-02 1.0000E+00 1.1878E-02 1.1878E-02 1.1878E-02 42 4.564E+00 2.500E+01 3.400E-01 3.9070E-03 3.9070E-03 1.0000E+00 3.9070E-03 3.9070E-03 3.9070E-03 43 5.176E+00 3.000E+01 3.400E-01 1.2851E-03 1.2851E-03 1.0000E+00 1.2851E-03 1.2851E-03 1.2851E-03 44 5.789E+00 3.500E+01 3.400E-01 4.2270E-04 4.2270E-04 1.0000E+00 4.2270E-04 4.2270E-04 4.2270E-04 45 4.000E+00 0.000E+00 0.000E+00 1.0000E+00 1.0000E+00 1.0000E+00 1.0000E+00 1.0000E+00 1.0000E+00 46 1.506E+00 1.000E-01 7.100E-01 9.8103E-01 9.8103E-01 1.0000E+00 9.8103E-01 9.8103E-01 9.8103E-01 47 1.515E+00 2.500E-01 7.100E-01 9.5195E-01 9.5195E-01 1.0000E+00 9.5195E-01 9.5195E-01 9.5195E-01 48 1.529E+00 5.000E-01 7.100E-01 9.0266E-01 9.0266E-01 1.0000E+00 9.0266E-01 9.0266E-01 9.0266E-01 49 1.559E+00 1.000E+00 7.100E-01 8.0509E-01 8.0509E-01 1.0000E+00 8.0509E-01 8.0509E-01 8.0509E-01 50 1.588E+00 1.500E+00 7.100E-01 7.1325E-01 7.1325E-01 1.0000E+00 7.1325E-01 7.1325E-01 7.1325E-01 51 1.617E+00 2.000E+00 7.100E-01 6.2950E-01 6.2950E-01 1.0000E+00 6.2950E-01 6.2950E-01 6.2950E-01 52 1.676E+00 3.000E+00 7.100E-01 4.8771E-01 4.8771E-01 1.0000E+00 4.8771E-01 4.8771E-01 4.8771E-01 53 1.735E+00 4.000E+00 7.100E-01 3.7676E-01 3.7676E-01 1.0000E+00 3.7676E-01 3.7676E-01 3.7676E-01 54 1.793E+00 5.000E+00 7.100E-01 2.9078E-01 2.9078E-01 1.0000E+00 2.9078E-01 2.9078E-01 2.9078E-01 55 1.852E+00 6.000E+00 7.100E-01 2.2436E-01 2.2436E-01 1.0000E+00 2.2436E-01 2.2436E-01 2.2436E-01 56 1.911E+00 7.000E+00 7.100E-01 1.7310E-01 1.7310E-01 1.0000E+00 1.7310E-01 1.7310E-01 1.7310E-01 57 1.969E+00 8.000E+00 7.100E-01 1.3354E-01 1.3354E-01 1.0000E+00 1.3354E-01 1.3354E-01 1.3354E-01 58 2.028E+00 9.000E+00 7.100E-01 1.0303E-01 1.0303E-01 1.0000E+00 1.0303E-01 1.0303E-01 1.0303E-01 59 2.087E+00 1.000E+01 7.100E-01 7.9483E-02 7.9483E-02 1.0000E+00 7.9483E-02 7.9483E-02 7.9483E-02 60 2.234E+00 1.250E+01 7.100E-01 4.1551E-02 4.1551E-02 1.0000E+00 4.1551E-02 4.1551E-02 4.1551E-02 61 2.380E+00 1.500E+01 7.100E-01 2.1722E-02 2.1722E-02 1.0000E+00 2.1722E-02 2.1722E-02 2.1722E-02 62 2.527E+00 1.750E+01 7.100E-01 1.1356E-02 1.1356E-02 1.0000E+00 1.1356E-02 1.1356E-02 1.1356E-02 63 2.674E+00 2.000E+01 7.100E-01 5.9364E-03 5.9364E-03 1.0000E+00 5.9364E-03 5.9364E-03 5.9364E-03 64 2.967E+00 2.500E+01 7.100E-01 1.6224E-03 1.6224E-03 1.0000E+00 1.6224E-03 1.6224E-03 1.6224E-03 65 3.261E+00 3.000E+01 7.100E-01 4.4337E-04 4.4337E-04 1.0000E+00 4.4337E-04 4.4337E-04 4.4337E-04 66 3.554E+00 3.500E+01 7.100E-01 1.2117E-04 1.2117E-04 1.0000E+00 1.2117E-04 1.2117E-04 1.2117E-04 67 4.000E+00 0.000E+00 0.000E+00 1.0000E+00 1.0000E+00 1.0000E+00 1.0000E+00 1.0000E+00 1.0000E+00 68 1.500E+00 1.000E-01 8.100E+01 9.8102E-01 9.8102E-01 1.0000E+00 9.8102E-01 9.8102E-01 9.8102E-01 69 1.500E+00 2.500E-01 8.100E+01 9.5174E-01 9.5174E-01 1.0000E+00 9.5174E-01 9.5174E-01 9.5174E-01 70 1.500E+00 5.000E-01 8.100E+01 9.0115E-01 9.0115E-01 1.0000E+00 9.0115E-01 9.0115E-01 9.0115E-01 71 1.501E+00 1.000E+00 8.100E+01 7.9566E-01 7.9566E-01 1.0000E+00 7.9566E-01 7.9566E-01 7.9566E-01 72 1.501E+00 1.500E+00 8.100E+01 6.8859E-01 6.8859E-01 1.0000E+00 6.8859E-01 6.8859E-01 6.8859E-01 73 1.501E+00 2.000E+00 8.100E+01 5.8433E-01 5.8433E-01 1.0000E+00 5.8433E-01 5.8433E-01 5.8433E-01 74 1.502E+00 3.000E+00 8.100E+01 3.9722E-01 3.9722E-01 1.0000E+00 3.9722E-01 3.9722E-01 3.9722E-01 75 1.502E+00 4.000E+00 8.100E+01 2.5065E-01 2.5065E-01 1.0000E+00 2.5065E-01 2.5065E-01 2.5065E-01 76 1.503E+00 5.000E+00 8.100E+01 1.4720E-01 1.4720E-01 1.0000E+00 1.4720E-01 1.4720E-01 1.4720E-01 77 1.503E+00 6.000E+00 8.100E+01 8.0654E-02 8.0654E-02 1.0000E+00 8.0654E-02 8.0654E-02 8.0654E-02 78 1.504E+00 7.000E+00 8.100E+01 4.1333E-02 4.1333E-02 1.0000E+00 4.1333E-02 4.1333E-02 4.1333E-02 79 1.504E+00 8.000E+00 8.100E+01 1.9857E-02 1.9857E-02 1.0000E+00 1.9857E-02 1.9857E-02 1.9857E-02 80 1.505E+00 9.000E+00 8.100E+01 8.9630E-03 8.9630E-03 1.0000E+00 8.9630E-03 8.9630E-03 8.9630E-03 81 1.505E+00 1.000E+01 8.100E+01 3.8090E-03 3.8090E-03 1.0000E+00 3.8090E-03 3.8090E-03 3.8090E-03 82 1.506E+00 1.250E+01 8.100E+01 3.4909E-04 3.4909E-04 1.0000E+00 3.4909E-04 3.4909E-04 3.4909E-04 83 1.508E+00 1.500E+01 8.100E+01 2.2895E-05 2.2895E-05 1.0000E+00 2.2895E-05 2.2895E-05 2.2895E-05 84 1.509E+00 1.750E+01 8.100E+01 1.1037E-06 1.1037E-06 1.0000E+00 1.1037E-06 1.1037E-06 1.1037E-06 85 1.510E+00 2.000E+01 8.100E+01 4.0062E-08 4.0062E-08 1.0000E+00 4.0062E-08 4.0062E-08 4.0062E-08 86 1.513E+00 2.500E+01 8.100E+01 2.4552E-11 2.4552E-11 1.0000E+00 2.4552E-11 2.4552E-11 2.4552E-11 87 1.515E+00 3.000E+01 8.100E+01 6.1413E-15 6.1413E-15 1.0000E+00 6.1413E-15 6.1413E-15 6.1413E-15 88 1.518E+00 3.500E+01 8.100E+01 7.1221E-19 7.1221E-19 1.0000E+00 7.1221E-19 7.1221E-19 7.1221E-19 --------------------------------------------------------------------------------------------------------------------- NOTE: N(0) is the initial number of cells (time=0 day), N(t) is the expected number of unirradiated (control) cells at TSIM, i.e., N(t)=N(0)*EXP[LN(2)*TSIM/TPOT]. The surviving fraction S(D) is the expected number of cells, per irradiated cell, that has not sustained lethal DNA damage (no corrections for repopulation effects). NSC(t) is the expected number of cells that survive irradiation, including repopulation effects (recommended method). The product N(t)*S(D) is an alternate method of estimating the surviving fraction with repopulation effects. DFAR TABLE: Mutagenesis and the induction of enhanced genetic instability (GI). Key GI model parameters are: (1-FRDL)=0.0%, NCM=1, NCG=1, and NCG*PGH*PGA=4.250E-06. ====================================================================================================== Dose Dose Rate -- NON-LETHAL MUTATIONS PER CELL -- **** PROBABILITY PER CELL **** SIM ID (Gy) (Gy/h) Mutations Residual Total AGF EGI EGI/SF ------------------------------------------------------------------------------------------------------ 1 0.000E+00 0.000E+00 0.000E+00 0.00E+00 0.00000E+00 0.000E+00 0.000E+00 0.000E+00 2 1.000E-01 2.400E-01 2.481E+00 0.00E+00 2.48088E+00 1.034E-05 1.034E-05 1.054E-05 3 2.500E-01 2.400E-01 6.201E+00 0.00E+00 6.20112E+00 2.510E-05 2.510E-05 2.635E-05 4 5.000E-01 2.400E-01 1.240E+01 0.00E+00 1.23999E+01 4.768E-05 4.768E-05 5.270E-05 5 1.000E+00 2.400E-01 2.479E+01 0.00E+00 2.47949E+01 8.583E-05 8.583E-05 1.054E-04 6 1.500E+00 2.400E-01 3.719E+01 0.00E+00 3.71890E+01 1.158E-04 1.158E-04 1.580E-04 7 2.000E+00 2.400E-01 4.958E+01 0.00E+00 4.95829E+01 1.388E-04 1.388E-04 2.107E-04 8 3.000E+00 2.400E-01 7.437E+01 0.00E+00 7.43707E+01 1.684E-04 1.684E-04 3.160E-04 9 4.000E+00 2.400E-01 9.916E+01 0.00E+00 9.91585E+01 1.816E-04 1.816E-04 4.213E-04 10 5.000E+00 2.400E-01 1.239E+02 0.00E+00 1.23946E+02 1.836E-04 1.836E-04 5.266E-04 11 6.000E+00 2.400E-01 1.487E+02 0.00E+00 1.48734E+02 1.782E-04 1.782E-04 6.319E-04 12 7.000E+00 2.400E-01 1.735E+02 0.00E+00 1.73522E+02 1.681E-04 1.681E-04 7.372E-04 13 8.000E+00 2.400E-01 1.983E+02 0.00E+00 1.98310E+02 1.554E-04 1.554E-04 8.425E-04 14 9.000E+00 2.400E-01 2.231E+02 0.00E+00 2.23097E+02 1.414E-04 1.414E-04 9.477E-04 15 1.000E+01 2.400E-01 2.479E+02 0.00E+00 2.47885E+02 1.271E-04 1.271E-04 1.053E-03 16 1.250E+01 2.400E-01 3.099E+02 0.00E+00 3.09855E+02 9.342E-05 9.342E-05 1.316E-03 17 1.500E+01 2.400E-01 3.718E+02 0.00E+00 3.71824E+02 6.594E-05 6.594E-05 1.579E-03 18 1.750E+01 2.400E-01 4.338E+02 0.00E+00 4.33794E+02 4.525E-05 4.525E-05 1.842E-03 19 2.000E+01 2.400E-01 4.958E+02 0.00E+00 4.95763E+02 3.042E-05 3.042E-05 2.105E-03 20 2.500E+01 2.400E-01 6.197E+02 0.00E+00 6.19702E+02 1.316E-05 1.316E-05 2.630E-03 21 3.000E+01 2.400E-01 7.436E+02 0.00E+00 7.43641E+02 5.463E-06 5.463E-06 3.155E-03 22 3.500E+01 2.400E-01 8.676E+02 0.00E+00 8.67580E+02 2.205E-06 2.205E-06 3.680E-03 23 0.000E+00 0.000E+00 0.000E+00 0.00E+00 0.00000E+00 0.000E+00 0.000E+00 0.000E+00 24 1.000E-01 3.400E-01 2.481E+00 0.00E+00 2.48086E+00 1.034E-05 1.034E-05 1.054E-05 25 2.500E-01 3.400E-01 6.201E+00 0.00E+00 6.20097E+00 2.509E-05 2.509E-05 2.635E-05 26 5.000E-01 3.400E-01 1.240E+01 0.00E+00 1.23990E+01 4.763E-05 4.763E-05 5.269E-05 27 1.000E+00 3.400E-01 2.479E+01 0.00E+00 2.47909E+01 8.548E-05 8.548E-05 1.054E-04 28 1.500E+00 3.400E-01 3.718E+01 0.00E+00 3.71806E+01 1.148E-04 1.148E-04 1.580E-04 29 2.000E+00 3.400E-01 4.957E+01 0.00E+00 4.95697E+01 1.370E-04 1.370E-04 2.106E-04 30 3.000E+00 3.400E-01 7.435E+01 0.00E+00 7.43475E+01 1.645E-04 1.645E-04 3.159E-04 31 4.000E+00 3.400E-01 9.913E+01 0.00E+00 9.91251E+01 1.756E-04 1.756E-04 4.212E-04 32 5.000E+00 3.400E-01 1.239E+02 0.00E+00 1.23903E+02 1.757E-04 1.757E-04 5.264E-04 33 6.000E+00 3.400E-01 1.487E+02 0.00E+00 1.48680E+02 1.688E-04 1.688E-04 6.317E-04 34 7.000E+00 3.400E-01 1.735E+02 0.00E+00 1.73458E+02 1.577E-04 1.577E-04 7.369E-04 35 8.000E+00 3.400E-01 1.982E+02 0.00E+00 1.98236E+02 1.442E-04 1.442E-04 8.421E-04 36 9.000E+00 3.400E-01 2.230E+02 0.00E+00 2.23013E+02 1.299E-04 1.299E-04 9.474E-04 37 1.000E+01 3.400E-01 2.478E+02 0.00E+00 2.47791E+02 1.156E-04 1.156E-04 1.053E-03 38 1.250E+01 3.400E-01 3.097E+02 0.00E+00 3.09735E+02 8.283E-05 8.283E-05 1.316E-03 39 1.500E+01 3.400E-01 3.717E+02 0.00E+00 3.71679E+02 5.700E-05 5.700E-05 1.578E-03 40 1.750E+01 3.400E-01 4.336E+02 0.00E+00 4.33623E+02 3.813E-05 3.813E-05 1.841E-03 41 2.000E+01 3.400E-01 4.956E+02 0.00E+00 4.95567E+02 2.499E-05 2.499E-05 2.104E-03 42 2.500E+01 3.400E-01 6.195E+02 0.00E+00 6.19455E+02 1.027E-05 1.027E-05 2.629E-03 43 3.000E+01 3.400E-01 7.433E+02 0.00E+00 7.43343E+02 4.054E-06 4.054E-06 3.154E-03 44 3.500E+01 3.400E-01 8.672E+02 0.00E+00 8.67231E+02 1.555E-06 1.555E-06 3.679E-03 45 0.000E+00 0.000E+00 0.000E+00 0.00E+00 0.00000E+00 0.000E+00 0.000E+00 0.000E+00 46 1.000E-01 7.100E-01 2.481E+00 0.00E+00 2.48085E+00 1.034E-05 1.034E-05 1.054E-05 47 2.500E-01 7.100E-01 6.201E+00 0.00E+00 6.20076E+00 2.509E-05 2.509E-05 2.635E-05 48 5.000E-01 7.100E-01 1.240E+01 0.00E+00 1.23976E+01 4.756E-05 4.756E-05 5.269E-05 49 1.000E+00 7.100E-01 2.478E+01 0.00E+00 2.47832E+01 8.479E-05 8.479E-05 1.053E-04 50 1.500E+00 7.100E-01 3.716E+01 0.00E+00 3.71621E+01 1.126E-04 1.126E-04 1.579E-04 51 2.000E+00 7.100E-01 4.954E+01 0.00E+00 4.95372E+01 1.325E-04 1.325E-04 2.105E-04 52 3.000E+00 7.100E-01 7.428E+01 0.00E+00 7.42820E+01 1.539E-04 1.539E-04 3.156E-04 53 4.000E+00 7.100E-01 9.902E+01 0.00E+00 9.90238E+01 1.585E-04 1.585E-04 4.208E-04 54 5.000E+00 7.100E-01 1.238E+02 0.00E+00 1.23765E+02 1.529E-04 1.529E-04 5.259E-04 55 6.000E+00 7.100E-01 1.485E+02 0.00E+00 1.48506E+02 1.416E-04 1.416E-04 6.309E-04 56 7.000E+00 7.100E-01 1.732E+02 0.00E+00 1.73246E+02 1.274E-04 1.274E-04 7.360E-04 57 8.000E+00 7.100E-01 1.980E+02 0.00E+00 1.97987E+02 1.123E-04 1.123E-04 8.411E-04 58 9.000E+00 7.100E-01 2.227E+02 0.00E+00 2.22727E+02 9.748E-05 9.748E-05 9.461E-04 59 1.000E+01 7.100E-01 2.475E+02 0.00E+00 2.47468E+02 8.355E-05 8.355E-05 1.051E-03 60 1.250E+01 7.100E-01 3.093E+02 0.00E+00 3.09319E+02 5.459E-05 5.459E-05 1.314E-03 61 1.500E+01 7.100E-01 3.712E+02 0.00E+00 3.71171E+02 3.424E-05 3.424E-05 1.576E-03 62 1.750E+01 7.100E-01 4.330E+02 0.00E+00 4.33022E+02 2.088E-05 2.088E-05 1.839E-03 63 2.000E+01 7.100E-01 4.949E+02 0.00E+00 4.94873E+02 1.247E-05 1.247E-05 2.101E-03 64 2.500E+01 7.100E-01 6.186E+02 0.00E+00 6.18576E+02 4.259E-06 4.259E-06 2.625E-03 65 3.000E+01 7.100E-01 7.423E+02 0.00E+00 7.42279E+02 1.397E-06 1.397E-06 3.150E-03 66 3.500E+01 7.100E-01 8.660E+02 0.00E+00 8.65982E+02 4.451E-07 4.451E-07 3.674E-03 67 0.000E+00 0.000E+00 0.000E+00 0.00E+00 0.00000E+00 0.000E+00 0.000E+00 0.000E+00 68 1.000E-01 8.100E+01 2.481E+00 0.00E+00 2.48083E+00 1.034E-05 1.034E-05 1.054E-05 69 2.500E-01 8.100E+01 6.201E+00 0.00E+00 6.20053E+00 2.508E-05 2.508E-05 2.635E-05 70 5.000E-01 8.100E+01 1.240E+01 0.00E+00 1.23959E+01 4.747E-05 4.747E-05 5.268E-05 71 1.000E+00 8.100E+01 2.477E+01 0.00E+00 2.47714E+01 8.376E-05 8.376E-05 1.053E-04 72 1.500E+00 8.100E+01 3.713E+01 0.00E+00 3.71269E+01 1.086E-04 1.086E-04 1.578E-04 73 2.000E+00 8.100E+01 4.946E+01 0.00E+00 4.94627E+01 1.228E-04 1.228E-04 2.102E-04 74 3.000E+00 8.100E+01 7.408E+01 0.00E+00 7.40767E+01 1.250E-04 1.250E-04 3.148E-04 75 4.000E+00 8.100E+01 9.862E+01 0.00E+00 9.86163E+01 1.050E-04 1.050E-04 4.190E-04 76 5.000E+00 8.100E+01 1.231E+02 0.00E+00 1.23084E+02 7.698E-05 7.698E-05 5.230E-04 77 6.000E+00 8.100E+01 1.475E+02 0.00E+00 1.47482E+02 5.054E-05 5.054E-05 6.266E-04 78 7.000E+00 8.100E+01 1.718E+02 0.00E+00 1.71814E+02 3.017E-05 3.017E-05 7.299E-04 79 8.000E+00 8.100E+01 1.961E+02 0.00E+00 1.96081E+02 1.654E-05 1.654E-05 8.330E-04 80 9.000E+00 8.100E+01 2.203E+02 0.00E+00 2.20285E+02 8.387E-06 8.387E-06 9.358E-04 81 1.000E+01 8.100E+01 2.444E+02 0.00E+00 2.44430E+02 3.955E-06 3.955E-06 1.038E-03 82 1.250E+01 8.100E+01 3.045E+02 0.00E+00 3.04540E+02 4.515E-07 4.515E-07 1.293E-03 83 1.500E+01 8.100E+01 3.643E+02 0.00E+00 3.64315E+02 3.542E-08 3.542E-08 1.547E-03 84 1.750E+01 8.100E+01 4.238E+02 0.00E+00 4.23783E+02 1.986E-09 1.986E-09 1.799E-03 85 2.000E+01 8.100E+01 4.830E+02 0.00E+00 4.82967E+02 8.215E-11 8.215E-11 2.051E-03 86 2.500E+01 8.100E+01 6.006E+02 0.00E+00 6.00570E+02 6.259E-14 6.259E-14 2.549E-03 87 3.000E+01 8.100E+01 7.173E+02 0.00E+00 7.17276E+02 1.869E-17 1.869E-17 3.044E-03 88 3.500E+01 8.100E+01 8.332E+02 0.00E+00 8.33214E+02 2.518E-21 2.518E-21 3.535E-03 ------------------------------------------------------------------------------------------------------ AGF: function or expression of at least 1 of the 1 critical gene targets is altered. EGI: altered gene function or expression causes enhanced genetic instability. NEOM TABLE: Neoplastic transformation as a function of dose and dose rate at t=42.000 days. Parameters: TFS=1.1500E-05 (1/wk), TFU=2.0000E-03 (1/wk), NCM=1, NCG=1, and NCG*PGH*PGA=4.3E-06. ====================================================================================================== Dose Dose Rate Non-Lethal Genetic Instability *** TRANSFORMATION FREQUENCY *** SIM ID (Gy) (Gy/h) Mutations EGI EGI/SF BKG TPS TPI ------------------------------------------------------------------------------------------------------ 1 0.000E+00 0.000E+00 0.000E+00 0.000E+00 0.000E+00 6.8995E-05 6.8995E-05 6.8995E-05 2 1.000E-01 2.400E-01 2.481E+00 1.034E-05 1.054E-05 6.8994E-05 6.9120E-05 6.7811E-05 3 2.500E-01 2.400E-01 6.201E+00 2.510E-05 2.635E-05 6.8993E-05 6.9308E-05 6.6002E-05 4 5.000E-01 2.400E-01 1.240E+01 4.768E-05 5.270E-05 6.8992E-05 6.9620E-05 6.2987E-05 5 1.000E+00 2.400E-01 2.479E+01 8.583E-05 1.054E-04 6.8988E-05 7.0245E-05 5.7218E-05 6 1.500E+00 2.400E-01 3.719E+01 1.158E-04 1.580E-04 6.8984E-05 7.0869E-05 5.1926E-05 7 2.000E+00 2.400E-01 4.958E+01 1.388E-04 2.107E-04 6.8981E-05 7.1494E-05 4.7112E-05 8 3.000E+00 2.400E-01 7.437E+01 1.684E-04 3.160E-04 6.8973E-05 7.2743E-05 3.8770E-05 9 4.000E+00 2.400E-01 9.916E+01 1.816E-04 4.213E-04 6.8966E-05 7.3992E-05 3.1895E-05 10 5.000E+00 2.400E-01 1.239E+02 1.836E-04 5.266E-04 6.8959E-05 7.5241E-05 2.6232E-05 11 6.000E+00 2.400E-01 1.487E+02 1.782E-04 6.319E-04 6.8952E-05 7.6489E-05 2.1568E-05 12 7.000E+00 2.400E-01 1.735E+02 1.681E-04 7.372E-04 6.8944E-05 7.7738E-05 1.7729E-05 13 8.000E+00 2.400E-01 1.983E+02 1.554E-04 8.425E-04 6.8937E-05 7.8986E-05 1.4569E-05 14 9.000E+00 2.400E-01 2.231E+02 1.414E-04 9.477E-04 6.8930E-05 8.0234E-05 1.1970E-05 15 1.000E+01 2.400E-01 2.479E+02 1.271E-04 1.053E-03 6.8923E-05 8.1483E-05 9.8318E-06 16 1.250E+01 2.400E-01 3.099E+02 9.342E-05 1.316E-03 6.8904E-05 8.4602E-05 6.0054E-06 17 1.500E+01 2.400E-01 3.718E+02 6.594E-05 1.579E-03 6.8886E-05 8.7721E-05 3.6632E-06 18 1.750E+01 2.400E-01 4.338E+02 4.525E-05 1.842E-03 6.8868E-05 9.0839E-05 2.2317E-06 19 2.000E+01 2.400E-01 4.958E+02 3.042E-05 2.105E-03 6.8850E-05 9.3956E-05 1.3579E-06 20 2.500E+01 2.400E-01 6.197E+02 1.316E-05 2.630E-03 6.8814E-05 1.0019E-04 5.0114E-07 21 3.000E+01 2.400E-01 7.436E+02 5.463E-06 3.155E-03 6.8778E-05 1.0642E-04 1.8422E-07 22 3.500E+01 2.400E-01 8.676E+02 2.205E-06 3.680E-03 6.8741E-05 1.1264E-04 6.7488E-08 23 0.000E+00 0.000E+00 0.000E+00 0.000E+00 0.000E+00 6.8995E-05 6.8995E-05 6.8995E-05 24 1.000E-01 3.400E-01 2.481E+00 1.034E-05 1.054E-05 6.8994E-05 6.9120E-05 6.7810E-05 25 2.500E-01 3.400E-01 6.201E+00 2.509E-05 2.635E-05 6.8993E-05 6.9308E-05 6.5992E-05 26 5.000E-01 3.400E-01 1.240E+01 4.763E-05 5.269E-05 6.8992E-05 6.9620E-05 6.2932E-05 27 1.000E+00 3.400E-01 2.479E+01 8.548E-05 1.054E-04 6.8988E-05 7.0245E-05 5.6990E-05 28 1.500E+00 3.400E-01 3.718E+01 1.148E-04 1.580E-04 6.8984E-05 7.0869E-05 5.1494E-05 29 2.000E+00 3.400E-01 4.957E+01 1.370E-04 2.106E-04 6.8981E-05 7.1493E-05 4.6495E-05 30 3.000E+00 3.400E-01 7.435E+01 1.645E-04 3.159E-04 6.8973E-05 7.2742E-05 3.7878E-05 31 4.000E+00 3.400E-01 9.913E+01 1.756E-04 4.212E-04 6.8966E-05 7.3990E-05 3.0846E-05 32 5.000E+00 3.400E-01 1.239E+02 1.757E-04 5.264E-04 6.8959E-05 7.5239E-05 2.5113E-05 33 6.000E+00 3.400E-01 1.487E+02 1.688E-04 6.317E-04 6.8952E-05 7.6487E-05 2.0439E-05 34 7.000E+00 3.400E-01 1.735E+02 1.577E-04 7.369E-04 6.8944E-05 7.7735E-05 1.6630E-05 35 8.000E+00 3.400E-01 1.982E+02 1.442E-04 8.421E-04 6.8937E-05 7.8982E-05 1.3528E-05 36 9.000E+00 3.400E-01 2.230E+02 1.299E-04 9.474E-04 6.8930E-05 8.0230E-05 1.1002E-05 37 1.000E+01 3.400E-01 2.478E+02 1.156E-04 1.053E-03 6.8923E-05 8.1478E-05 8.9451E-06 38 1.250E+01 3.400E-01 3.097E+02 8.283E-05 1.316E-03 6.8904E-05 8.4596E-05 5.3266E-06 39 1.500E+01 3.400E-01 3.717E+02 5.700E-05 1.578E-03 6.8886E-05 8.7714E-05 3.1675E-06 40 1.750E+01 3.400E-01 4.336E+02 3.813E-05 1.841E-03 6.8868E-05 9.0831E-05 1.8812E-06 41 2.000E+01 3.400E-01 4.956E+02 2.499E-05 2.104E-03 6.8850E-05 9.3946E-05 1.1159E-06 42 2.500E+01 3.400E-01 6.195E+02 1.027E-05 2.629E-03 6.8814E-05 1.0018E-04 3.9139E-07 43 3.000E+01 3.400E-01 7.433E+02 4.054E-06 3.154E-03 6.8778E-05 1.0640E-04 1.3674E-07 44 3.500E+01 3.400E-01 8.672E+02 1.555E-06 3.679E-03 6.8741E-05 1.1262E-04 4.7607E-08 45 0.000E+00 0.000E+00 0.000E+00 0.000E+00 0.000E+00 6.8995E-05 6.8995E-05 6.8995E-05 46 1.000E-01 7.100E-01 2.481E+00 1.034E-05 1.054E-05 6.8994E-05 6.9120E-05 6.7809E-05 47 2.500E-01 7.100E-01 6.201E+00 2.509E-05 2.635E-05 6.8993E-05 6.9308E-05 6.5978E-05 48 5.000E-01 7.100E-01 1.240E+01 4.756E-05 5.269E-05 6.8992E-05 6.9620E-05 6.2843E-05 49 1.000E+00 7.100E-01 2.478E+01 8.479E-05 1.053E-04 6.8988E-05 7.0244E-05 5.6553E-05 50 1.500E+00 7.100E-01 3.716E+01 1.126E-04 1.579E-04 6.8984E-05 7.0868E-05 5.0547E-05 51 2.000E+00 7.100E-01 4.954E+01 1.325E-04 2.105E-04 6.8981E-05 7.1492E-05 4.5004E-05 52 3.000E+00 7.100E-01 7.428E+01 1.539E-04 3.156E-04 6.8973E-05 7.2739E-05 3.5475E-05 53 4.000E+00 7.100E-01 9.902E+01 1.585E-04 4.208E-04 6.8966E-05 7.3985E-05 2.7874E-05 54 5.000E+00 7.100E-01 1.238E+02 1.529E-04 5.259E-04 6.8959E-05 7.5232E-05 2.1876E-05 55 6.000E+00 7.100E-01 1.485E+02 1.416E-04 6.309E-04 6.8952E-05 7.6478E-05 1.7159E-05 56 7.000E+00 7.100E-01 1.732E+02 1.274E-04 7.360E-04 6.8944E-05 7.7724E-05 1.3454E-05 57 8.000E+00 7.100E-01 1.980E+02 1.123E-04 8.411E-04 6.8937E-05 7.8970E-05 1.0546E-05 58 9.000E+00 7.100E-01 2.227E+02 9.748E-05 9.461E-04 6.8930E-05 8.0216E-05 8.2643E-06 59 1.000E+01 7.100E-01 2.475E+02 8.355E-05 1.051E-03 6.8923E-05 8.1462E-05 6.4748E-06 60 1.250E+01 7.100E-01 3.093E+02 5.459E-05 1.314E-03 6.8905E-05 8.4575E-05 3.5142E-06 61 1.500E+01 7.100E-01 3.712E+02 3.424E-05 1.576E-03 6.8886E-05 8.7688E-05 1.9048E-06 62 1.750E+01 7.100E-01 4.330E+02 2.088E-05 1.839E-03 6.8868E-05 9.0800E-05 1.0311E-06 63 2.000E+01 7.100E-01 4.949E+02 1.247E-05 2.101E-03 6.8850E-05 9.3912E-05 5.5750E-07 64 2.500E+01 7.100E-01 6.186E+02 4.259E-06 2.625E-03 6.8814E-05 1.0013E-04 1.6245E-07 65 3.000E+01 7.100E-01 7.423E+02 1.397E-06 3.150E-03 6.8778E-05 1.0635E-04 4.7152E-08 66 3.500E+01 7.100E-01 8.660E+02 4.451E-07 3.674E-03 6.8742E-05 1.1256E-04 1.3639E-08 67 0.000E+00 0.000E+00 0.000E+00 0.000E+00 0.000E+00 6.8995E-05 6.8995E-05 6.8995E-05 68 1.000E-01 8.100E+01 2.481E+00 1.034E-05 1.054E-05 6.8994E-05 6.9120E-05 6.7808E-05 69 2.500E-01 8.100E+01 6.201E+00 2.508E-05 2.635E-05 6.8993E-05 6.9308E-05 6.5963E-05 70 5.000E-01 8.100E+01 1.240E+01 4.747E-05 5.268E-05 6.8992E-05 6.9620E-05 6.2738E-05 71 1.000E+00 8.100E+01 2.477E+01 8.376E-05 1.053E-04 6.8988E-05 7.0244E-05 5.5890E-05 72 1.500E+00 8.100E+01 3.713E+01 1.086E-04 1.578E-04 6.8984E-05 7.0866E-05 4.8798E-05 73 2.000E+00 8.100E+01 4.946E+01 1.228E-04 2.102E-04 6.8981E-05 7.1488E-05 4.1772E-05 74 3.000E+00 8.100E+01 7.408E+01 1.250E-04 3.148E-04 6.8974E-05 7.2728E-05 2.8889E-05 75 4.000E+00 8.100E+01 9.862E+01 1.050E-04 4.190E-04 6.8966E-05 7.3965E-05 1.8539E-05 76 5.000E+00 8.100E+01 1.231E+02 7.698E-05 5.230E-04 6.8959E-05 7.5197E-05 1.1069E-05 77 6.000E+00 8.100E+01 1.475E+02 5.054E-05 6.266E-04 6.8952E-05 7.6426E-05 6.1641E-06 78 7.000E+00 8.100E+01 1.718E+02 3.017E-05 7.299E-04 6.8945E-05 7.7652E-05 3.2096E-06 79 8.000E+00 8.100E+01 1.961E+02 1.654E-05 8.330E-04 6.8938E-05 7.8874E-05 1.5662E-06 80 9.000E+00 8.100E+01 2.203E+02 8.387E-06 9.358E-04 6.8931E-05 8.0093E-05 7.1787E-07 81 1.000E+01 8.100E+01 2.444E+02 3.955E-06 1.038E-03 6.8924E-05 8.1309E-05 3.0971E-07 82 1.250E+01 8.100E+01 3.045E+02 4.515E-07 1.293E-03 6.8906E-05 8.4335E-05 2.9440E-08 83 1.500E+01 8.100E+01 3.643E+02 3.542E-08 1.547E-03 6.8888E-05 8.7343E-05 1.9998E-09 84 1.750E+01 8.100E+01 4.238E+02 1.986E-09 1.799E-03 6.8871E-05 9.0336E-05 9.9703E-11 85 2.000E+01 8.100E+01 4.830E+02 8.215E-11 2.051E-03 6.8854E-05 9.3313E-05 3.7383E-12 86 2.500E+01 8.100E+01 6.006E+02 6.259E-14 2.549E-03 6.8819E-05 9.9227E-05 2.4362E-15 87 3.000E+01 8.100E+01 7.173E+02 1.869E-17 3.044E-03 6.8785E-05 1.0509E-04 6.4540E-19 88 3.500E+01 8.100E+01 8.332E+02 2.518E-21 3.535E-03 6.8751E-05 1.1092E-04 7.8996E-23 ------------------------------------------------------------------------------------------------------ TPS: Transformation frequency per survivor, TPI: Transformation frequency per irradiated cell EGI: Probabilty random mutational events caused enhanced genetic instability (EGI). BKG: Background (spontaneous) cell transformation frequency RMRM TABLE: LQ model dose protraction factor(s) and cell survival estimates (FRDL=100.0%). LQ model parameters are: alpha = 0.188 (1/Gy), alpha/beta = 4.510 (Gy) , lamda = 8.014E-01 (1/h). ====================================================================================================== --- Duration (h) --- Dose Dose Rate* ***** G FACTOR ***** ******* SF(dose) ******* SIM ID Exposure Sim (Gy) (Gy/h) GL GEFF SF1 SF2 ------------------------------------------------------------------------------------------------------ 1 2.778E-13 9.600E+01 0.000E+00 0.000E+00 0.000E+00 0.000E+00 1.0000E+00 1.000000E+00 2 4.167E-01 3.642E+01 1.000E-01 2.400E-01 8.974E-01 8.966E-01 9.8106E-01 9.810579E-01 3 1.042E+00 3.704E+01 2.500E-01 2.400E-01 7.713E-01 7.698E-01 9.5229E-01 9.522974E-01 4 2.083E+00 3.808E+01 5.000E-01 2.400E-01 6.155E-01 6.134E-01 9.0470E-01 9.047187E-01 5 4.167E+00 4.017E+01 1.000E+00 2.400E-01 4.259E-01 4.237E-01 8.1447E-01 8.145441E-01 6 6.250E+00 4.225E+01 1.500E+00 2.400E-01 3.201E-01 3.181E-01 7.3256E-01 7.326949E-01 7 8.333E+00 4.433E+01 2.000E+00 2.400E-01 2.547E-01 2.530E-01 6.5877E-01 6.589598E-01 8 1.250E+01 4.850E+01 3.000E+00 2.400E-01 1.797E-01 1.784E-01 5.3271E-01 5.329675E-01 9 1.667E+01 5.267E+01 4.000E+00 2.400E-01 1.385E-01 1.375E-01 4.3076E-01 4.310613E-01 10 2.083E+01 5.683E+01 5.000E+00 2.400E-01 1.126E-01 1.118E-01 3.4833E-01 3.486399E-01 11 2.500E+01 6.100E+01 6.000E+00 2.400E-01 9.484E-02 9.411E-02 2.8167E-01 2.819780E-01 12 2.917E+01 6.517E+01 7.000E+00 2.400E-01 8.190E-02 8.126E-02 2.2777E-01 2.280623E-01 13 3.333E+01 6.933E+01 8.000E+00 2.400E-01 7.206E-02 7.150E-02 1.8418E-01 1.844555E-01 14 3.750E+01 7.350E+01 9.000E+00 2.400E-01 6.433E-02 6.383E-02 1.4893E-01 1.491866E-01 15 4.167E+01 7.767E+01 1.000E+01 2.400E-01 5.810E-02 5.764E-02 1.2043E-01 1.206613E-01 16 5.208E+01 8.808E+01 1.250E+01 2.400E-01 4.677E-02 4.640E-02 7.0814E-02 7.098446E-02 17 6.250E+01 9.850E+01 1.500E+01 2.400E-01 3.913E-02 3.882E-02 4.1638E-02 4.175982E-02 18 7.292E+01 1.089E+02 1.750E+01 2.400E-01 3.364E-02 3.337E-02 2.4483E-02 2.456711E-02 19 8.333E+01 1.193E+02 2.000E+01 2.400E-01 2.950E-02 2.926E-02 1.4396E-02 1.445271E-02 20 1.042E+02 1.402E+02 2.500E+01 2.400E-01 2.367E-02 2.348E-02 4.9773E-03 5.001959E-03 21 1.250E+02 1.610E+02 3.000E+01 2.400E-01 1.977E-02 1.961E-02 1.7209E-03 1.731135E-03 22 1.458E+02 1.818E+02 3.500E+01 2.400E-01 1.697E-02 1.683E-02 5.9497E-04 5.991308E-04 23 2.778E-13 9.600E+01 0.000E+00 0.000E+00 0.000E+00 0.000E+00 1.0000E+00 1.000000E+00 24 2.941E-01 3.629E+01 1.000E-01 3.400E-01 9.258E-01 9.250E-01 9.8105E-01 9.810463E-01 25 7.353E-01 3.674E+01 2.500E-01 3.400E-01 8.294E-01 8.277E-01 9.5215E-01 9.521541E-01 26 1.471E+00 3.747E+01 5.000E-01 3.400E-01 7.002E-01 6.976E-01 9.0390E-01 9.039276E-01 27 2.941E+00 3.894E+01 1.000E+00 3.400E-01 5.226E-01 5.194E-01 8.1120E-01 8.113089E-01 28 4.412E+00 4.041E+01 1.500E+00 3.400E-01 4.103E-01 4.072E-01 7.2640E-01 7.266138E-01 29 5.882E+00 4.188E+01 2.000E+00 3.400E-01 3.351E-01 3.322E-01 6.5002E-01 6.503350E-01 30 8.824E+00 4.482E+01 3.000E+00 3.400E-01 2.429E-01 2.405E-01 5.2027E-01 5.207217E-01 31 1.176E+01 4.776E+01 4.000E+00 3.400E-01 1.896E-01 1.877E-01 4.1637E-01 4.168979E-01 32 1.471E+01 5.071E+01 5.000E+00 3.400E-01 1.553E-01 1.537E-01 3.3321E-01 3.337719E-01 33 1.765E+01 5.365E+01 6.000E+00 3.400E-01 1.314E-01 1.300E-01 2.6666E-01 2.672202E-01 34 2.059E+01 5.659E+01 7.000E+00 3.400E-01 1.139E-01 1.126E-01 2.1341E-01 2.139385E-01 35 2.353E+01 5.953E+01 8.000E+00 3.400E-01 1.004E-01 9.935E-02 1.7079E-01 1.712807E-01 36 2.647E+01 6.247E+01 9.000E+00 3.400E-01 8.983E-02 8.885E-02 1.3668E-01 1.371286E-01 37 2.941E+01 6.541E+01 1.000E+01 3.400E-01 8.125E-02 8.036E-02 1.0938E-01 1.097861E-01 38 3.676E+01 7.276E+01 1.250E+01 3.400E-01 6.557E-02 6.485E-02 6.2668E-02 6.296460E-02 39 4.412E+01 8.012E+01 1.500E+01 3.400E-01 5.497E-02 5.435E-02 3.5905E-02 3.611148E-02 40 5.147E+01 8.747E+01 1.750E+01 3.400E-01 4.731E-02 4.678E-02 2.0572E-02 2.071067E-02 41 5.882E+01 9.482E+01 2.000E+01 3.400E-01 4.152E-02 4.106E-02 1.1786E-02 1.187799E-02 42 7.353E+01 1.095E+02 2.500E+01 3.400E-01 3.336E-02 3.299E-02 3.8690E-03 3.906978E-03 43 8.824E+01 1.242E+02 3.000E+01 3.400E-01 2.788E-02 2.757E-02 1.2700E-03 1.285105E-03 44 1.029E+02 1.389E+02 3.500E+01 3.400E-01 2.395E-02 2.368E-02 4.1690E-04 4.227041E-04 45 2.778E-13 9.600E+01 0.000E+00 0.000E+00 0.000E+00 0.000E+00 1.0000E+00 1.000000E+00 46 1.408E-01 3.614E+01 1.000E-01 7.100E-01 9.634E-01 9.625E-01 9.8103E-01 9.810310E-01 47 3.521E-01 3.635E+01 2.500E-01 7.100E-01 9.122E-01 9.102E-01 9.5195E-01 9.519499E-01 48 7.042E-01 3.670E+01 5.000E-01 7.100E-01 8.357E-01 8.322E-01 9.0263E-01 9.026633E-01 49 1.408E+00 3.741E+01 1.000E+00 7.100E-01 7.098E-01 7.045E-01 8.0491E-01 8.050889E-01 50 2.113E+00 3.811E+01 1.500E+00 7.100E-01 6.119E-01 6.057E-01 7.1283E-01 7.132475E-01 51 2.817E+00 3.882E+01 2.000E+00 7.100E-01 5.345E-01 5.279E-01 6.2881E-01 6.295028E-01 52 4.225E+00 4.023E+01 3.000E+00 7.100E-01 4.221E-01 4.156E-01 4.8652E-01 4.877051E-01 53 5.634E+00 4.163E+01 4.000E+00 7.100E-01 3.459E-01 3.399E-01 3.7525E-01 3.767556E-01 54 7.042E+00 4.304E+01 5.000E+00 7.100E-01 2.918E-01 2.863E-01 2.8913E-01 2.907812E-01 55 8.451E+00 4.445E+01 6.000E+00 7.100E-01 2.518E-01 2.468E-01 2.2271E-01 2.243615E-01 56 9.859E+00 4.586E+01 7.000E+00 7.100E-01 2.211E-01 2.166E-01 1.7152E-01 1.730977E-01 57 1.127E+01 4.727E+01 8.000E+00 7.100E-01 1.970E-01 1.929E-01 1.3210E-01 1.335432E-01 58 1.268E+01 4.868E+01 9.000E+00 7.100E-01 1.775E-01 1.737E-01 1.0174E-01 1.030264E-01 59 1.408E+01 5.008E+01 1.000E+01 7.100E-01 1.615E-01 1.580E-01 7.8351E-02 7.948292E-02 60 1.761E+01 5.361E+01 1.250E+01 7.100E-01 1.317E-01 1.288E-01 4.0782E-02 4.155145E-02 61 2.113E+01 5.713E+01 1.500E+01 7.100E-01 1.111E-01 1.087E-01 2.1227E-02 2.172192E-02 62 2.465E+01 6.065E+01 1.750E+01 7.100E-01 9.612E-02 9.397E-02 1.1049E-02 1.135561E-02 63 2.817E+01 6.417E+01 2.000E+01 7.100E-01 8.467E-02 8.276E-02 5.7510E-03 5.936390E-03 64 3.521E+01 7.121E+01 2.500E+01 7.100E-01 6.836E-02 6.681E-02 1.5581E-03 1.622358E-03 65 4.225E+01 7.825E+01 3.000E+01 7.100E-01 5.732E-02 5.600E-02 4.2213E-04 4.433746E-04 66 4.930E+01 8.530E+01 3.500E+01 7.100E-01 4.934E-02 4.821E-02 1.1437E-04 1.211700E-04 67 2.778E-13 9.600E+01 0.000E+00 0.000E+00 0.000E+00 0.000E+00 1.0000E+00 1.000000E+00 68 1.235E-03 3.600E+01 1.000E-01 8.100E+01 9.997E-01 9.988E-01 9.8102E-01 9.810163E-01 69 3.086E-03 3.600E+01 2.500E-01 8.100E+01 9.992E-01 9.969E-01 9.5173E-01 9.517355E-01 70 6.173E-03 3.601E+01 5.000E-01 8.100E+01 9.984E-01 9.938E-01 9.0111E-01 9.011483E-01 71 1.235E-02 3.601E+01 1.000E+00 8.100E+01 9.967E-01 9.877E-01 7.9537E-01 7.956641E-01 72 1.852E-02 3.602E+01 1.500E+00 8.100E+01 9.951E-01 9.817E-01 6.8773E-01 6.885940E-01 73 2.469E-02 3.602E+01 2.000E+00 8.100E+01 9.934E-01 9.757E-01 5.8260E-01 5.843265E-01 74 3.704E-02 3.604E+01 3.000E+00 8.100E+01 9.902E-01 9.640E-01 3.9334E-01 3.972230E-01 75 4.938E-02 3.605E+01 4.000E+00 8.100E+01 9.869E-01 9.525E-01 2.4497E-01 2.506493E-01 76 6.173E-02 3.606E+01 5.000E+00 8.100E+01 9.837E-01 9.413E-01 1.4084E-01 1.471969E-01 77 7.407E-02 3.607E+01 6.000E+00 8.100E+01 9.805E-01 9.303E-01 7.4814E-02 8.065419E-02 78 8.642E-02 3.609E+01 7.000E+00 8.100E+01 9.773E-01 9.196E-01 3.6745E-02 4.133332E-02 79 9.877E-02 3.610E+01 8.000E+00 8.100E+01 9.741E-01 9.091E-01 1.6700E-02 1.985740E-02 80 1.111E-01 3.611E+01 9.000E+00 8.100E+01 9.710E-01 8.988E-01 7.0286E-03 8.963018E-03 81 1.235E-01 3.612E+01 1.000E+01 8.100E+01 9.678E-01 8.887E-01 2.7414E-03 3.809050E-03 82 1.543E-01 3.615E+01 1.250E+01 8.100E+01 9.600E-01 8.645E-01 1.8765E-04 3.490875E-04 83 1.852E-01 3.619E+01 1.500E+01 8.100E+01 9.523E-01 8.414E-01 8.1137E-06 2.289534E-05 84 2.160E-01 3.622E+01 1.750E+01 8.100E+01 9.447E-01 8.195E-01 2.2413E-07 1.103692E-06 85 2.469E-01 3.625E+01 2.000E+01 8.100E+01 9.372E-01 7.986E-01 3.9989E-09 4.006195E-08 86 3.086E-01 3.631E+01 2.500E+01 8.100E+01 9.224E-01 7.597E-01 3.5786E-13 2.455237E-11 87 3.704E-01 3.637E+01 3.000E+01 8.100E+01 9.080E-01 7.241E-01 6.3141E-18 6.141274E-15 88 4.321E-01 3.643E+01 3.500E+01 8.100E+01 8.939E-01 6.915E-01 2.3756E-23 7.122113E-19 ------------------------------------------------------------------------------------------------------ GL=[2*[x+exp(-x)-1]/(x*x), where x = {lamda}*{irradiation time} and GEFF=-(alpha+LOG(SF)/D)/(beta*D). In the formula for GEFF, SF is surviving fraction as computed using the RMR model. The effects of lethal residual damage are included in the GEFF dose protraction factor but not GL. The SF estimates are: SF1=EXP{-dose*[alpha+gl*beta*dose]} and SF2=EXP{-dose*(alpha+geff*beta*dose)}. QECK TABLE: Tumor control probability (TCP) estimates as a function of dose and dose rate. Cell kinetic parameters are: N(0)=F0*KAP*VOL=1.00000E+00, TCC=10.0000 h, Tpot=20.000 days. The *MAX* estimate is recommended (the other TCP estimates are mainly included in the table for diagnostic purposes). ===================================================================================================================== TSIM DOSE ---- EXPECTED NUMBER OF CELLS ---- ------ TUMOR CONTROL PROBABILITY (TCP) ------- SIM ID (day) (Gy) N(0)*S(D) N(t)*S(D) NSC(t) N(0)*S(D) N(t)*S(D) NSC(t) *MAX* --------------------------------------------------------------------------------------------------------------------- 1 4.000E+00 0.000E+00 1.0000E+00 1.0000E+00 1.0000E+00 3.6788E-01 3.6788E-01 3.6788E-01 3.6788E-01 2 1.517E+00 1.000E-01 9.8106E-01 9.8106E-01 9.8106E-01 3.7491E-01 3.7491E-01 3.7491E-01 3.7491E-01 3 1.543E+00 2.500E-01 9.5230E-01 9.5230E-01 9.5230E-01 3.8585E-01 3.8585E-01 3.8585E-01 3.8585E-01 4 1.587E+00 5.000E-01 9.0472E-01 9.0472E-01 9.0472E-01 4.0466E-01 4.0466E-01 4.0466E-01 4.0466E-01 5 1.674E+00 1.000E+00 8.1454E-01 8.1454E-01 8.1454E-01 4.4284E-01 4.4284E-01 4.4284E-01 4.4284E-01 6 1.760E+00 1.500E+00 7.3269E-01 7.3269E-01 7.3269E-01 4.8061E-01 4.8061E-01 4.8061E-01 4.8061E-01 7 1.847E+00 2.000E+00 6.5896E-01 6.5896E-01 6.5896E-01 5.1739E-01 5.1739E-01 5.1739E-01 5.1739E-01 8 2.021E+00 3.000E+00 5.3297E-01 5.3297E-01 5.3297E-01 5.8686E-01 5.8686E-01 5.8686E-01 5.8686E-01 9 2.194E+00 4.000E+00 4.3106E-01 4.3106E-01 4.3106E-01 6.4982E-01 6.4982E-01 6.4982E-01 6.4982E-01 10 2.368E+00 5.000E+00 3.4864E-01 3.4864E-01 3.4864E-01 7.0565E-01 7.0565E-01 7.0565E-01 7.0565E-01 11 2.542E+00 6.000E+00 2.8198E-01 2.8198E-01 2.8198E-01 7.5429E-01 7.5429E-01 7.5429E-01 7.5429E-01 12 2.715E+00 7.000E+00 2.2806E-01 2.2806E-01 2.2806E-01 7.9607E-01 7.9607E-01 7.9607E-01 7.9607E-01 13 2.889E+00 8.000E+00 1.8446E-01 1.8446E-01 1.8446E-01 8.3156E-01 8.3156E-01 8.3156E-01 8.3156E-01 14 3.062E+00 9.000E+00 1.4919E-01 1.4919E-01 1.4919E-01 8.6141E-01 8.6141E-01 8.6141E-01 8.6141E-01 15 3.236E+00 1.000E+01 1.2066E-01 1.2066E-01 1.2066E-01 8.8633E-01 8.8633E-01 8.8633E-01 8.8633E-01 16 3.670E+00 1.250E+01 7.0984E-02 7.0984E-02 7.0984E-02 9.3148E-01 9.3148E-01 9.3148E-01 9.3148E-01 17 4.104E+00 1.500E+01 4.1760E-02 4.1760E-02 4.1760E-02 9.5910E-01 9.5910E-01 9.5910E-01 9.5910E-01 18 4.538E+00 1.750E+01 2.4567E-02 2.4567E-02 2.4567E-02 9.7573E-01 9.7573E-01 9.7573E-01 9.7573E-01 19 4.972E+00 2.000E+01 1.4453E-02 1.4453E-02 1.4453E-02 9.8565E-01 9.8565E-01 9.8565E-01 9.8565E-01 20 5.840E+00 2.500E+01 5.0020E-03 5.0020E-03 5.0020E-03 9.9501E-01 9.9501E-01 9.9501E-01 9.9501E-01 21 6.708E+00 3.000E+01 1.7311E-03 1.7311E-03 1.7311E-03 9.9827E-01 9.9827E-01 9.9827E-01 9.9827E-01 22 7.576E+00 3.500E+01 5.9913E-04 5.9913E-04 5.9913E-04 9.9940E-01 9.9940E-01 9.9940E-01 9.9940E-01 23 4.000E+00 0.000E+00 1.0000E+00 1.0000E+00 1.0000E+00 3.6788E-01 3.6788E-01 3.6788E-01 3.6788E-01 24 1.512E+00 1.000E-01 9.8105E-01 9.8105E-01 9.8105E-01 3.7492E-01 3.7492E-01 3.7492E-01 3.7492E-01 25 1.531E+00 2.500E-01 9.5215E-01 9.5215E-01 9.5215E-01 3.8591E-01 3.8591E-01 3.8591E-01 3.8591E-01 26 1.561E+00 5.000E-01 9.0393E-01 9.0393E-01 9.0393E-01 4.0498E-01 4.0498E-01 4.0498E-01 4.0498E-01 27 1.623E+00 1.000E+00 8.1131E-01 8.1131E-01 8.1131E-01 4.4428E-01 4.4428E-01 4.4428E-01 4.4428E-01 28 1.684E+00 1.500E+00 7.2661E-01 7.2661E-01 7.2661E-01 4.8354E-01 4.8354E-01 4.8354E-01 4.8354E-01 29 1.745E+00 2.000E+00 6.5034E-01 6.5034E-01 6.5034E-01 5.2187E-01 5.2187E-01 5.2187E-01 5.2187E-01 30 1.868E+00 3.000E+00 5.2072E-01 5.2072E-01 5.2072E-01 5.9409E-01 5.9409E-01 5.9409E-01 5.9409E-01 31 1.990E+00 4.000E+00 4.1690E-01 4.1690E-01 4.1690E-01 6.5909E-01 6.5909E-01 6.5909E-01 6.5909E-01 32 2.113E+00 5.000E+00 3.3377E-01 3.3377E-01 3.3377E-01 7.1622E-01 7.1622E-01 7.1622E-01 7.1622E-01 33 2.235E+00 6.000E+00 2.6722E-01 2.6722E-01 2.6722E-01 7.6550E-01 7.6550E-01 7.6550E-01 7.6550E-01 34 2.358E+00 7.000E+00 2.1394E-01 2.1394E-01 2.1394E-01 8.0740E-01 8.0740E-01 8.0740E-01 8.0740E-01 35 2.480E+00 8.000E+00 1.7128E-01 1.7128E-01 1.7128E-01 8.4259E-01 8.4259E-01 8.4259E-01 8.4259E-01 36 2.603E+00 9.000E+00 1.3713E-01 1.3713E-01 1.3713E-01 8.7186E-01 8.7186E-01 8.7186E-01 8.7186E-01 37 2.725E+00 1.000E+01 1.0979E-01 1.0979E-01 1.0979E-01 8.9603E-01 8.9603E-01 8.9603E-01 8.9603E-01 38 3.032E+00 1.250E+01 6.2965E-02 6.2965E-02 6.2965E-02 9.3898E-01 9.3898E-01 9.3898E-01 9.3898E-01 39 3.338E+00 1.500E+01 3.6111E-02 3.6111E-02 3.6111E-02 9.6453E-01 9.6453E-01 9.6453E-01 9.6453E-01 40 3.645E+00 1.750E+01 2.0711E-02 2.0711E-02 2.0711E-02 9.7950E-01 9.7950E-01 9.7950E-01 9.7950E-01 41 3.951E+00 2.000E+01 1.1878E-02 1.1878E-02 1.1878E-02 9.8819E-01 9.8819E-01 9.8819E-01 9.8819E-01 42 4.564E+00 2.500E+01 3.9070E-03 3.9070E-03 3.9070E-03 9.9610E-01 9.9610E-01 9.9610E-01 9.9610E-01 43 5.176E+00 3.000E+01 1.2851E-03 1.2851E-03 1.2851E-03 9.9872E-01 9.9872E-01 9.9872E-01 9.9872E-01 44 5.789E+00 3.500E+01 4.2270E-04 4.2270E-04 4.2270E-04 9.9958E-01 9.9958E-01 9.9958E-01 9.9958E-01 45 4.000E+00 0.000E+00 1.0000E+00 1.0000E+00 1.0000E+00 3.6788E-01 3.6788E-01 3.6788E-01 3.6788E-01 46 1.506E+00 1.000E-01 9.8103E-01 9.8103E-01 9.8103E-01 3.7492E-01 3.7492E-01 3.7492E-01 3.7492E-01 47 1.515E+00 2.500E-01 9.5195E-01 9.5195E-01 9.5195E-01 3.8599E-01 3.8599E-01 3.8599E-01 3.8599E-01 48 1.529E+00 5.000E-01 9.0266E-01 9.0266E-01 9.0266E-01 4.0549E-01 4.0549E-01 4.0549E-01 4.0549E-01 49 1.559E+00 1.000E+00 8.0509E-01 8.0509E-01 8.0509E-01 4.4705E-01 4.4705E-01 4.4705E-01 4.4705E-01 50 1.588E+00 1.500E+00 7.1325E-01 7.1325E-01 7.1325E-01 4.9005E-01 4.9005E-01 4.9005E-01 4.9005E-01 51 1.617E+00 2.000E+00 6.2950E-01 6.2950E-01 6.2950E-01 5.3286E-01 5.3286E-01 5.3286E-01 5.3286E-01 52 1.676E+00 3.000E+00 4.8771E-01 4.8771E-01 4.8771E-01 6.1403E-01 6.1403E-01 6.1403E-01 6.1403E-01 53 1.735E+00 4.000E+00 3.7676E-01 3.7676E-01 3.7676E-01 6.8608E-01 6.8608E-01 6.8608E-01 6.8608E-01 54 1.793E+00 5.000E+00 2.9078E-01 2.9078E-01 2.9078E-01 7.4768E-01 7.4768E-01 7.4768E-01 7.4768E-01 55 1.852E+00 6.000E+00 2.2436E-01 2.2436E-01 2.2436E-01 7.9903E-01 7.9903E-01 7.9903E-01 7.9903E-01 56 1.911E+00 7.000E+00 1.7310E-01 1.7310E-01 1.7310E-01 8.4106E-01 8.4106E-01 8.4106E-01 8.4106E-01 57 1.969E+00 8.000E+00 1.3354E-01 1.3354E-01 1.3354E-01 8.7499E-01 8.7499E-01 8.7499E-01 8.7499E-01 58 2.028E+00 9.000E+00 1.0303E-01 1.0303E-01 1.0303E-01 9.0210E-01 9.0210E-01 9.0210E-01 9.0210E-01 59 2.087E+00 1.000E+01 7.9483E-02 7.9483E-02 7.9483E-02 9.2359E-01 9.2359E-01 9.2359E-01 9.2359E-01 60 2.234E+00 1.250E+01 4.1551E-02 4.1551E-02 4.1551E-02 9.5930E-01 9.5930E-01 9.5930E-01 9.5930E-01 61 2.380E+00 1.500E+01 2.1722E-02 2.1722E-02 2.1722E-02 9.7851E-01 9.7851E-01 9.7851E-01 9.7851E-01 62 2.527E+00 1.750E+01 1.1356E-02 1.1356E-02 1.1356E-02 9.8871E-01 9.8871E-01 9.8871E-01 9.8871E-01 63 2.674E+00 2.000E+01 5.9364E-03 5.9364E-03 5.9364E-03 9.9408E-01 9.9408E-01 9.9408E-01 9.9408E-01 64 2.967E+00 2.500E+01 1.6224E-03 1.6224E-03 1.6224E-03 9.9838E-01 9.9838E-01 9.9838E-01 9.9838E-01 65 3.261E+00 3.000E+01 4.4337E-04 4.4337E-04 4.4337E-04 9.9956E-01 9.9956E-01 9.9956E-01 9.9956E-01 66 3.554E+00 3.500E+01 1.2117E-04 1.2117E-04 1.2117E-04 9.9988E-01 9.9988E-01 9.9988E-01 9.9988E-01 67 4.000E+00 0.000E+00 1.0000E+00 1.0000E+00 1.0000E+00 3.6788E-01 3.6788E-01 3.6788E-01 3.6788E-01 68 1.500E+00 1.000E-01 9.8102E-01 9.8102E-01 9.8102E-01 3.7493E-01 3.7493E-01 3.7493E-01 3.7493E-01 69 1.500E+00 2.500E-01 9.5174E-01 9.5174E-01 9.5174E-01 3.8607E-01 3.8607E-01 3.8607E-01 3.8607E-01 70 1.500E+00 5.000E-01 9.0115E-01 9.0115E-01 9.0115E-01 4.0610E-01 4.0610E-01 4.0610E-01 4.0610E-01 71 1.501E+00 1.000E+00 7.9566E-01 7.9566E-01 7.9566E-01 4.5128E-01 4.5128E-01 4.5128E-01 4.5128E-01 72 1.501E+00 1.500E+00 6.8859E-01 6.8859E-01 6.8859E-01 5.0228E-01 5.0228E-01 5.0228E-01 5.0228E-01 73 1.501E+00 2.000E+00 5.8433E-01 5.8433E-01 5.8433E-01 5.5748E-01 5.5748E-01 5.5748E-01 5.5748E-01 74 1.502E+00 3.000E+00 3.9722E-01 3.9722E-01 3.9722E-01 6.7218E-01 6.7218E-01 6.7218E-01 6.7218E-01 75 1.502E+00 4.000E+00 2.5065E-01 2.5065E-01 2.5065E-01 7.7830E-01 7.7830E-01 7.7830E-01 7.7830E-01 76 1.503E+00 5.000E+00 1.4720E-01 1.4720E-01 1.4720E-01 8.6312E-01 8.6312E-01 8.6312E-01 8.6312E-01 77 1.503E+00 6.000E+00 8.0654E-02 8.0654E-02 8.0654E-02 9.2251E-01 9.2251E-01 9.2251E-01 9.2251E-01 78 1.504E+00 7.000E+00 4.1333E-02 4.1333E-02 4.1333E-02 9.5951E-01 9.5951E-01 9.5951E-01 9.5951E-01 79 1.504E+00 8.000E+00 1.9857E-02 1.9857E-02 1.9857E-02 9.8034E-01 9.8034E-01 9.8034E-01 9.8034E-01 80 1.505E+00 9.000E+00 8.9630E-03 8.9630E-03 8.9630E-03 9.9108E-01 9.9108E-01 9.9108E-01 9.9108E-01 81 1.505E+00 1.000E+01 3.8090E-03 3.8090E-03 3.8090E-03 9.9620E-01 9.9620E-01 9.9620E-01 9.9620E-01 82 1.506E+00 1.250E+01 3.4909E-04 3.4909E-04 3.4909E-04 9.9965E-01 9.9965E-01 9.9965E-01 9.9965E-01 83 1.508E+00 1.500E+01 2.2895E-05 2.2895E-05 2.2895E-05 9.9998E-01 9.9998E-01 9.9998E-01 9.9998E-01 84 1.509E+00 1.750E+01 1.1037E-06 1.1037E-06 1.1037E-06 1.0000E+00 1.0000E+00 1.0000E+00 1.0000E+00 85 1.510E+00 2.000E+01 4.0062E-08 4.0062E-08 4.0062E-08 1.0000E+00 1.0000E+00 1.0000E+00 1.0000E+00 86 1.513E+00 2.500E+01 2.4552E-11 2.4552E-11 2.4552E-11 1.0000E+00 1.0000E+00 1.0000E+00 1.0000E+00 87 1.515E+00 3.000E+01 6.1413E-15 6.1413E-15 6.1413E-15 1.0000E+00 1.0000E+00 1.0000E+00 1.0000E+00 88 1.518E+00 3.500E+01 7.1221E-19 7.1221E-19 7.1221E-19 1.0000E+00 1.0000E+00 1.0000E+00 1.0000E+00 --------------------------------------------------------------------------------------------------------------------- NOTE: TCP={probability no cells survive}=EXP{-(expected number of surviving cells)}. TCP estimates are based on the expected number of surviving cells with and without corrections for repopulation effects. The *MAX* TCP is the peak (all time points after irradiation) estimate derived from NSC(t). RADX EXPOSURE SUMMARY ============================================================================== SCENARIO ----- DURATION ----- ------ DOSE (Gy) ----- -- DOSE RATE (Gy/h) -- NUMBER hours days Background Total Background Total* ------------------------------------------------------------------------------ 1 2.778E-13 1.157E-14 0.0000E+00 0.0000E+00 0.0000E+00 0.0000E+00 2 4.167E-01 1.736E-02 0.0000E+00 1.0000E-01 0.0000E+00 2.4000E-01 3 1.042E+00 4.340E-02 0.0000E+00 2.5000E-01 0.0000E+00 2.4000E-01 4 2.083E+00 8.681E-02 0.0000E+00 5.0000E-01 0.0000E+00 2.4000E-01 5 4.167E+00 1.736E-01 0.0000E+00 1.0000E+00 0.0000E+00 2.4000E-01 6 6.250E+00 2.604E-01 0.0000E+00 1.5000E+00 0.0000E+00 2.4000E-01 7 8.333E+00 3.472E-01 0.0000E+00 2.0000E+00 0.0000E+00 2.4000E-01 8 1.250E+01 5.208E-01 0.0000E+00 3.0000E+00 0.0000E+00 2.4000E-01 9 1.667E+01 6.944E-01 0.0000E+00 4.0000E+00 0.0000E+00 2.4000E-01 10 2.083E+01 8.681E-01 0.0000E+00 5.0000E+00 0.0000E+00 2.4000E-01 11 2.500E+01 1.042E+00 0.0000E+00 6.0000E+00 0.0000E+00 2.4000E-01 12 2.917E+01 1.215E+00 0.0000E+00 7.0000E+00 0.0000E+00 2.4000E-01 13 3.333E+01 1.389E+00 0.0000E+00 8.0000E+00 0.0000E+00 2.4000E-01 14 3.750E+01 1.562E+00 0.0000E+00 9.0000E+00 0.0000E+00 2.4000E-01 15 4.167E+01 1.736E+00 0.0000E+00 1.0000E+01 0.0000E+00 2.4000E-01 16 5.208E+01 2.170E+00 0.0000E+00 1.2500E+01 0.0000E+00 2.4000E-01 17 6.250E+01 2.604E+00 0.0000E+00 1.5000E+01 0.0000E+00 2.4000E-01 18 7.292E+01 3.038E+00 0.0000E+00 1.7500E+01 0.0000E+00 2.4000E-01 19 8.333E+01 3.472E+00 0.0000E+00 2.0000E+01 0.0000E+00 2.4000E-01 20 1.042E+02 4.340E+00 0.0000E+00 2.5000E+01 0.0000E+00 2.4000E-01 21 1.250E+02 5.208E+00 0.0000E+00 3.0000E+01 0.0000E+00 2.4000E-01 22 1.458E+02 6.076E+00 0.0000E+00 3.5000E+01 0.0000E+00 2.4000E-01 23 2.778E-13 1.157E-14 0.0000E+00 0.0000E+00 0.0000E+00 0.0000E+00 24 2.941E-01 1.225E-02 0.0000E+00 1.0000E-01 0.0000E+00 3.4000E-01 25 7.353E-01 3.064E-02 0.0000E+00 2.5000E-01 0.0000E+00 3.4000E-01 26 1.471E+00 6.127E-02 0.0000E+00 5.0000E-01 0.0000E+00 3.4000E-01 27 2.941E+00 1.225E-01 0.0000E+00 1.0000E+00 0.0000E+00 3.4000E-01 28 4.412E+00 1.838E-01 0.0000E+00 1.5000E+00 0.0000E+00 3.4000E-01 29 5.882E+00 2.451E-01 0.0000E+00 2.0000E+00 0.0000E+00 3.4000E-01 30 8.824E+00 3.676E-01 0.0000E+00 3.0000E+00 0.0000E+00 3.4000E-01 31 1.176E+01 4.902E-01 0.0000E+00 4.0000E+00 0.0000E+00 3.4000E-01 32 1.471E+01 6.127E-01 0.0000E+00 5.0000E+00 0.0000E+00 3.4000E-01 33 1.765E+01 7.353E-01 0.0000E+00 6.0000E+00 0.0000E+00 3.4000E-01 34 2.059E+01 8.578E-01 0.0000E+00 7.0000E+00 0.0000E+00 3.4000E-01 35 2.353E+01 9.804E-01 0.0000E+00 8.0000E+00 0.0000E+00 3.4000E-01 36 2.647E+01 1.103E+00 0.0000E+00 9.0000E+00 0.0000E+00 3.4000E-01 37 2.941E+01 1.225E+00 0.0000E+00 1.0000E+01 0.0000E+00 3.4000E-01 38 3.676E+01 1.532E+00 0.0000E+00 1.2500E+01 0.0000E+00 3.4000E-01 39 4.412E+01 1.838E+00 0.0000E+00 1.5000E+01 0.0000E+00 3.4000E-01 40 5.147E+01 2.145E+00 0.0000E+00 1.7500E+01 0.0000E+00 3.4000E-01 41 5.882E+01 2.451E+00 0.0000E+00 2.0000E+01 0.0000E+00 3.4000E-01 42 7.353E+01 3.064E+00 0.0000E+00 2.5000E+01 0.0000E+00 3.4000E-01 43 8.824E+01 3.676E+00 0.0000E+00 3.0000E+01 0.0000E+00 3.4000E-01 44 1.029E+02 4.289E+00 0.0000E+00 3.5000E+01 0.0000E+00 3.4000E-01 45 2.778E-13 1.157E-14 0.0000E+00 0.0000E+00 0.0000E+00 0.0000E+00 46 1.408E-01 5.869E-03 0.0000E+00 1.0000E-01 0.0000E+00 7.1000E-01 47 3.521E-01 1.467E-02 0.0000E+00 2.5000E-01 0.0000E+00 7.1000E-01 48 7.042E-01 2.934E-02 0.0000E+00 5.0000E-01 0.0000E+00 7.1000E-01 49 1.408E+00 5.869E-02 0.0000E+00 1.0000E+00 0.0000E+00 7.1000E-01 50 2.113E+00 8.803E-02 0.0000E+00 1.5000E+00 0.0000E+00 7.1000E-01 51 2.817E+00 1.174E-01 0.0000E+00 2.0000E+00 0.0000E+00 7.1000E-01 52 4.225E+00 1.761E-01 0.0000E+00 3.0000E+00 0.0000E+00 7.1000E-01 53 5.634E+00 2.347E-01 0.0000E+00 4.0000E+00 0.0000E+00 7.1000E-01 54 7.042E+00 2.934E-01 0.0000E+00 5.0000E+00 0.0000E+00 7.1000E-01 55 8.451E+00 3.521E-01 0.0000E+00 6.0000E+00 0.0000E+00 7.1000E-01 56 9.859E+00 4.108E-01 0.0000E+00 7.0000E+00 0.0000E+00 7.1000E-01 57 1.127E+01 4.695E-01 0.0000E+00 8.0000E+00 0.0000E+00 7.1000E-01 58 1.268E+01 5.282E-01 0.0000E+00 9.0000E+00 0.0000E+00 7.1000E-01 59 1.408E+01 5.869E-01 0.0000E+00 1.0000E+01 0.0000E+00 7.1000E-01 60 1.761E+01 7.336E-01 0.0000E+00 1.2500E+01 0.0000E+00 7.1000E-01 61 2.113E+01 8.803E-01 0.0000E+00 1.5000E+01 0.0000E+00 7.1000E-01 62 2.465E+01 1.027E+00 0.0000E+00 1.7500E+01 0.0000E+00 7.1000E-01 63 2.817E+01 1.174E+00 0.0000E+00 2.0000E+01 0.0000E+00 7.1000E-01 64 3.521E+01 1.467E+00 0.0000E+00 2.5000E+01 0.0000E+00 7.1000E-01 65 4.225E+01 1.761E+00 0.0000E+00 3.0000E+01 0.0000E+00 7.1000E-01 66 4.930E+01 2.054E+00 0.0000E+00 3.5000E+01 0.0000E+00 7.1000E-01 67 2.778E-13 1.157E-14 0.0000E+00 0.0000E+00 0.0000E+00 0.0000E+00 68 1.235E-03 5.144E-05 0.0000E+00 1.0000E-01 0.0000E+00 8.1000E+01 69 3.086E-03 1.286E-04 0.0000E+00 2.5000E-01 0.0000E+00 8.1000E+01 70 6.173E-03 2.572E-04 0.0000E+00 5.0000E-01 0.0000E+00 8.1000E+01 71 1.235E-02 5.144E-04 0.0000E+00 1.0000E+00 0.0000E+00 8.1000E+01 72 1.852E-02 7.716E-04 0.0000E+00 1.5000E+00 0.0000E+00 8.1000E+01 73 2.469E-02 1.029E-03 0.0000E+00 2.0000E+00 0.0000E+00 8.1000E+01 74 3.704E-02 1.543E-03 0.0000E+00 3.0000E+00 0.0000E+00 8.1000E+01 75 4.938E-02 2.058E-03 0.0000E+00 4.0000E+00 0.0000E+00 8.1000E+01 76 6.173E-02 2.572E-03 0.0000E+00 5.0000E+00 0.0000E+00 8.1000E+01 77 7.407E-02 3.086E-03 0.0000E+00 6.0000E+00 0.0000E+00 8.1000E+01 78 8.642E-02 3.601E-03 0.0000E+00 7.0000E+00 0.0000E+00 8.1000E+01 79 9.877E-02 4.115E-03 0.0000E+00 8.0000E+00 0.0000E+00 8.1000E+01 80 1.111E-01 4.630E-03 0.0000E+00 9.0000E+00 0.0000E+00 8.1000E+01 81 1.235E-01 5.144E-03 0.0000E+00 1.0000E+01 0.0000E+00 8.1000E+01 82 1.543E-01 6.430E-03 0.0000E+00 1.2500E+01 0.0000E+00 8.1000E+01 83 1.852E-01 7.716E-03 0.0000E+00 1.5000E+01 0.0000E+00 8.1000E+01 84 2.160E-01 9.002E-03 0.0000E+00 1.7500E+01 0.0000E+00 8.1000E+01 85 2.469E-01 1.029E-02 0.0000E+00 2.0000E+01 0.0000E+00 8.1000E+01 86 3.086E-01 1.286E-02 0.0000E+00 2.5000E+01 0.0000E+00 8.1000E+01 87 3.704E-01 1.543E-02 0.0000E+00 3.0000E+01 0.0000E+00 8.1000E+01 88 4.321E-01 1.800E-02 0.0000E+00 3.5000E+01 0.0000E+00 8.1000E+01 ------------------------------------------------------------------------------ * Dose rate is the delivered dose divided by the duration of the exposure scenario. Total VC execution time (min): 8.85000E-03 VC 2.00G 05-JUL-2003 20-JUL-2003 12:14:06 AM