VC 2.00I 13-JUL-2003 14-JUL-2003 04:12:45 PM by RD Stewart (trebor@purdue.edu) PROGRAM FILE INPUT/OUTPUT AND RUN-TIME OPTIONS: ================================================================================ CMD: p:\usr\bin\vc.exe g:\vc\archive\human\bladder\rt112\tlk\rt112.inp FNI: G:\vc\archive\human\Bladder\RT112\tlk\rt112.inp FNO: G:\vc\archive\human\Bladder\RT112\tlk\rt112.out RADX: G:\vc\archive\human\Bladder\RT112\tlk\rt112.radx (154 exposures) -------------------------------------------------------------------------------- QECK TABLE: Cell and tissue kinetic parameters. ================================================================================ Duration of cell cycle (TCC): 10.00000 h Potential doubling time (Tpot): 480.00000 h (= 20.000 days) Cell birth rate (AX): 1.6636E+00 cell/day (= LOG(2)/TCC) Cell death rate (BX): 1.6289E+00 cell/day [=AX-LOG(2)/TPOT] Net cell birth rate (AX-BX): 3.4657E-02 cell/day Initial Number of Cells: non-dividing: 1.00000E+00 (100.000% = 1-GF) dividing: 0.00000E+00 ( 0.000% = GF) total: 1.00000E+00 (100.000% total) Life Support Capacity of System: Initial system capacity utilization: 0.000000% (=F0) Peak cell density (cells/cm^3): 1.00000E+38 (=KAP) Tissue volume (cm^3): 1.00000E+00 (=VOL) Maximum number of cells (cells): 1.00000E+38 (=KAP*VOL) -------------------------------------------------------------------------------- TLKM TABLE: Summary of TLK parameters and related (derived) quantities. ======================================================================== G0/G1 DNA CONTENT: 5667.000 Mbp/cell = 3.482938E+12 Da/cell ENDOGENOUS DAMAGE: per (h-Da) per (h-Mbp) per (h-cell) Simple DSB = 0.00000E+00 0.00000E+00 0.00000E+00 Complex DSB = 0.00000E+00 0.00000E+00 0.00000E+00 Total DSB = 0.00000E+00 0.00000E+00 0.00000E+00 DAMAGE FORMATION: per (Gy-Da) per (Gy-Mbp) per (Gy-cell) Simple DSB = 5.74228E-12 3.52920E-03 20.000000 Complex DSB = 1.43557E-12 8.82301E-04 5.000000 Total DSB = 7.17785E-12 4.41151E-03 25.000000 DAMAGE REPAIR/MISREPAIR: A1= 7.500000E-01 (=75.000%) A2= 2.500000E-01 (=25.000%) PHI1= 1.824027E-02 (=1.824%) PHI2= 1.824027E-02 (=1.824%) (1-A1)*PHI1= 4.560068E-03 (=0.456%) (1-A2)*PHI2= 1.368020E-02 (=1.368%) (1-A1)*(1-PHI1)= 2.454399E-01 (=24.544%) (1-A2)*(1-PHI2)= 7.363198E-01 (=73.632%) RHT1= 0.219757 h (=13.19 minute) RHT2= 0.225344 h (=13.52 minute) LAM1= 3.1541543E+00 (1/h) LAM2= 3.0759524E+00 (1/h) BMR= 1.1452726E-03 (1/h) LAM1/BMR= 2.7540643E+03 LAM2/BMR= 2.6857819E+03 (LAM1+LAM2)/BMR= 5.4398462E+03 GAM= 0.250 ************** EQUIVALENT LQ MODEL PARAMETERS ************************** Simple Complex Total alpha: 9.1201E-02 + 6.8401E-02 = 1.5960239E-01 (1/Gy) beta: 2.2252E-02 + 5.5279E-03 = 2.7779827E-02 (1/Gy^2) alpha/beta: 5.7452621 (Gy) ------------------------------------------------------------------------ NOTE: 1 bp = 614.6 Da (amu) = 1.0205E-09 pg DFAR TABLE: Cell survival as a function of dose and dose rate (FRDL=100.0%). ====================================================================================================== --- Duration (h) --- Dose Dose Rate ---- LETHAL DAMAGE PER CELL ---- SIM ID Exposure Sim (Gy) (Gy/h) Mutations Residual Total SF(dose) ------------------------------------------------------------------------------------------------------ 1 2.778E-13 9.600E+01 0.000E+00 0.000E+00 0.000E+00 0.000E+00 0.0000E+00 1.000000E+00 2 1.667E-01 2.417E+01 1.000E-01 6.000E-01 1.620E-02 1.777E-13 1.6195E-02 9.839352E-01 3 4.167E-01 2.442E+01 2.500E-01 6.000E-01 4.107E-02 1.953E-13 4.1073E-02 9.597589E-01 4 8.333E-01 2.483E+01 5.000E-01 6.000E-01 8.322E-02 4.971E-13 8.3223E-02 9.201457E-01 5 1.667E+00 2.567E+01 1.000E+00 6.000E-01 1.682E-01 5.880E-13 1.6818E-01 8.452005E-01 6 2.500E+00 2.650E+01 1.500E+00 6.000E-01 2.533E-01 6.072E-13 2.5327E-01 7.762618E-01 7 3.333E+00 2.733E+01 2.000E+00 6.000E-01 3.384E-01 6.081E-13 3.3836E-01 7.129395E-01 8 5.000E+00 2.900E+01 3.000E+00 6.000E-01 5.085E-01 6.081E-13 5.0855E-01 6.013691E-01 9 6.667E+00 3.067E+01 4.000E+00 6.000E-01 6.787E-01 6.081E-13 6.7873E-01 5.072586E-01 10 8.333E+00 3.233E+01 5.000E+00 6.000E-01 8.489E-01 6.081E-13 8.4892E-01 4.278759E-01 11 1.000E+01 3.400E+01 6.000E+00 6.000E-01 1.019E+00 6.081E-13 1.0191E+00 3.609161E-01 12 1.167E+01 3.567E+01 7.000E+00 6.000E-01 1.189E+00 6.081E-13 1.1893E+00 3.044350E-01 13 1.333E+01 3.733E+01 8.000E+00 6.000E-01 1.359E+00 6.081E-13 1.3595E+00 2.567929E-01 14 1.500E+01 3.900E+01 9.000E+00 6.000E-01 1.530E+00 6.081E-13 1.5297E+00 2.166064E-01 15 1.667E+01 4.067E+01 1.000E+01 6.000E-01 1.700E+00 6.081E-13 1.6999E+00 1.827089E-01 16 2.083E+01 4.483E+01 1.250E+01 6.000E-01 2.125E+00 6.081E-13 2.1253E+00 1.193935E-01 17 2.500E+01 4.900E+01 1.500E+01 6.000E-01 2.551E+00 6.081E-13 2.5508E+00 7.801921E-02 18 2.917E+01 5.317E+01 1.750E+01 6.000E-01 2.976E+00 6.081E-13 2.9763E+00 5.098266E-02 19 3.333E+01 5.733E+01 2.000E+01 6.000E-01 3.402E+00 6.081E-13 3.4017E+00 3.331528E-02 20 4.167E+01 6.567E+01 2.500E+01 6.000E-01 4.253E+00 6.081E-13 4.2527E+00 1.422608E-02 21 5.000E+01 7.400E+01 3.000E+01 6.000E-01 5.104E+00 6.081E-13 5.1036E+00 6.074732E-03 22 5.833E+01 8.233E+01 3.500E+01 6.000E-01 5.955E+00 6.081E-13 5.9546E+00 2.593994E-03 23 2.778E-13 9.600E+01 0.000E+00 0.000E+00 0.000E+00 0.000E+00 0.0000E+00 1.000000E+00 24 8.333E-02 2.408E+01 1.000E-01 1.200E+00 1.622E-02 0.000E+00 1.6215E-02 9.839156E-01 25 2.083E-01 2.421E+01 2.500E-01 1.200E+00 4.131E-02 1.366E-13 4.1311E-02 9.595306E-01 26 4.167E-01 2.442E+01 5.000E-01 1.200E+00 8.449E-02 4.226E-13 8.4486E-02 9.189849E-01 27 8.333E-01 2.483E+01 1.000E+00 1.200E+00 1.733E-01 0.000E+00 1.7326E-01 8.409158E-01 28 1.250E+00 2.525E+01 1.500E+00 1.200E+00 2.632E-01 1.633E-13 2.6319E-01 7.685941E-01 29 1.667E+00 2.567E+01 2.000E+00 1.200E+00 3.534E-01 4.409E-14 3.5343E-01 7.022757E-01 30 2.500E+00 2.650E+01 3.000E+00 1.200E+00 5.341E-01 1.107E-13 5.3409E-01 5.862020E-01 31 3.333E+00 2.733E+01 4.000E+00 1.200E+00 7.148E-01 1.182E-13 7.1479E-01 4.892957E-01 32 4.167E+00 2.817E+01 5.000E+00 1.200E+00 8.955E-01 1.187E-13 8.9549E-01 4.084082E-01 33 5.000E+00 2.900E+01 6.000E+00 1.200E+00 1.076E+00 1.188E-13 1.0762E+00 3.408925E-01 34 5.833E+00 2.983E+01 7.000E+00 1.200E+00 1.257E+00 1.188E-13 1.2569E+00 2.845381E-01 35 6.667E+00 3.067E+01 8.000E+00 1.200E+00 1.438E+00 1.188E-13 1.4376E+00 2.374998E-01 36 7.500E+00 3.150E+01 9.000E+00 1.200E+00 1.618E+00 1.188E-13 1.6183E+00 1.982377E-01 37 8.333E+00 3.233E+01 1.000E+01 1.200E+00 1.799E+00 1.188E-13 1.7990E+00 1.654662E-01 38 1.042E+01 3.442E+01 1.250E+01 1.200E+00 2.251E+00 1.188E-13 2.2507E+00 1.053214E-01 39 1.250E+01 3.650E+01 1.500E+01 1.200E+00 2.702E+00 1.188E-13 2.7025E+00 6.703846E-02 40 1.458E+01 3.858E+01 1.750E+01 1.200E+00 3.154E+00 1.188E-13 3.1542E+00 4.267086E-02 41 1.667E+01 4.067E+01 2.000E+01 1.200E+00 3.606E+00 1.188E-13 3.6060E+00 2.716056E-02 42 2.083E+01 4.483E+01 2.500E+01 1.200E+00 4.509E+00 1.188E-13 4.5095E+00 1.100408E-02 43 2.500E+01 4.900E+01 3.000E+01 1.200E+00 5.413E+00 1.188E-13 5.4130E+00 4.458290E-03 44 2.917E+01 5.317E+01 3.500E+01 1.200E+00 6.316E+00 1.188E-13 6.3165E+00 1.806272E-03 45 2.778E-13 9.600E+01 0.000E+00 0.000E+00 0.000E+00 0.000E+00 0.0000E+00 1.000000E+00 46 3.333E-02 2.403E+01 1.000E-01 3.000E+00 1.623E-02 0.000E+00 1.6228E-02 9.839025E-01 47 8.333E-02 2.408E+01 2.500E-01 3.000E+00 4.149E-02 7.059E-13 4.1493E-02 9.593565E-01 48 1.667E-01 2.417E+01 5.000E-01 3.000E+00 8.566E-02 1.935E-14 8.5662E-02 9.179044E-01 49 3.333E-01 2.433E+01 1.000E+00 3.000E+00 1.797E-01 1.733E-13 1.7968E-01 8.355407E-01 50 5.000E-01 2.450E+01 1.500E+00 3.000E+00 2.786E-01 0.000E+00 2.7860E-01 7.568456E-01 51 6.667E-01 2.467E+01 2.000E+00 3.000E+00 3.804E-01 2.168E-14 3.8040E-01 6.835899E-01 52 1.000E+00 2.500E+01 3.000E+00 3.000E+00 5.884E-01 5.679E-13 5.8838E-01 5.552267E-01 53 1.333E+00 2.533E+01 4.000E+00 3.000E+00 7.989E-01 5.522E-13 7.9887E-01 4.498389E-01 54 1.667E+00 2.567E+01 5.000E+00 3.000E+00 1.010E+00 3.687E-13 1.0102E+00 3.641399E-01 55 2.000E+00 2.600E+01 6.000E+00 3.000E+00 1.222E+00 3.925E-13 1.2219E+00 2.946795E-01 56 2.333E+00 2.633E+01 7.000E+00 3.000E+00 1.434E+00 3.992E-13 1.4336E+00 2.384442E-01 57 2.667E+00 2.667E+01 8.000E+00 3.000E+00 1.645E+00 6.951E-13 1.6454E+00 1.929337E-01 58 3.000E+00 2.700E+01 9.000E+00 3.000E+00 1.857E+00 5.695E-13 1.8572E+00 1.561077E-01 59 3.333E+00 2.733E+01 1.000E+01 3.000E+00 2.069E+00 4.925E-13 2.0690E+00 1.263102E-01 60 4.167E+00 2.817E+01 1.250E+01 3.000E+00 2.599E+00 7.001E-14 2.5985E+00 7.438275E-02 61 5.000E+00 2.900E+01 1.500E+01 3.000E+00 3.128E+00 7.561E-13 3.1280E+00 4.380317E-02 62 5.833E+00 2.983E+01 1.750E+01 3.000E+00 3.658E+00 7.435E-13 3.6576E+00 2.579519E-02 63 6.667E+00 3.067E+01 2.000E+01 3.000E+00 4.187E+00 7.365E-13 4.1871E+00 1.519050E-02 64 8.333E+00 3.233E+01 2.500E+01 3.000E+00 5.246E+00 7.622E-13 5.2461E+00 5.267910E-03 65 1.000E+01 3.400E+01 3.000E+01 3.000E+00 6.305E+00 7.638E-13 6.3052E+00 1.826858E-03 66 1.167E+01 3.567E+01 3.500E+01 3.000E+00 7.364E+00 7.640E-13 7.3642E+00 6.335360E-04 67 2.778E-13 9.600E+01 0.000E+00 0.000E+00 0.000E+00 0.000E+00 0.0000E+00 1.000000E+00 68 1.667E-02 2.402E+01 1.000E-01 6.000E+00 1.623E-02 1.129E-13 1.6233E-02 9.838980E-01 69 4.167E-02 2.404E+01 2.500E-01 6.000E+00 4.156E-02 5.542E-14 4.1561E-02 9.592907E-01 70 8.333E-02 2.408E+01 5.000E-01 6.000E+00 8.616E-02 3.629E-14 8.6160E-02 9.174476E-01 71 1.667E-01 2.417E+01 1.000E+00 6.000E+00 1.830E-01 4.669E-13 1.8298E-01 8.327841E-01 72 2.500E-01 2.425E+01 1.500E+00 6.000E+00 2.879E-01 0.000E+00 2.8794E-01 7.498100E-01 73 3.333E-01 2.433E+01 2.000E+00 6.000E+00 3.991E-01 2.871E-13 3.9910E-01 6.709267E-01 74 5.000E-01 2.450E+01 3.000E+00 6.000E+00 6.345E-01 2.966E-13 6.3450E-01 5.302023E-01 75 6.667E-01 2.467E+01 4.000E+00 6.000E+00 8.811E-01 0.000E+00 8.8113E-01 4.143165E-01 76 8.333E-01 2.483E+01 5.000E+00 6.000E+00 1.134E+00 0.000E+00 1.1343E+00 3.216505E-01 77 1.000E+00 2.500E+01 6.000E+00 6.000E+00 1.391E+00 1.034E-13 1.3913E+00 2.487617E-01 78 1.167E+00 2.517E+01 7.000E+00 6.000E+00 1.650E+00 0.000E+00 1.6504E+00 1.919644E-01 79 1.333E+00 2.533E+01 8.000E+00 6.000E+00 1.911E+00 0.000E+00 1.9109E+00 1.479441E-01 80 1.500E+00 2.550E+01 9.000E+00 6.000E+00 2.172E+00 1.169E-13 2.1721E+00 1.139327E-01 81 1.667E+00 2.567E+01 1.000E+01 6.000E+00 2.434E+00 2.855E-13 2.4338E+00 8.770193E-02 82 2.083E+00 2.608E+01 1.250E+01 6.000E+00 3.089E+00 1.998E-13 3.0889E+00 4.555360E-02 83 2.500E+00 2.650E+01 1.500E+01 6.000E+00 3.744E+00 0.000E+00 3.7444E+00 2.365012E-02 84 2.917E+00 2.692E+01 1.750E+01 6.000E+00 4.400E+00 3.473E-13 4.4000E+00 1.227698E-02 85 3.333E+00 2.733E+01 2.000E+01 6.000E+00 5.056E+00 4.557E-14 5.0557E+00 6.372887E-03 86 4.167E+00 2.817E+01 2.500E+01 6.000E+00 6.367E+00 2.547E-13 6.3671E+00 1.717187E-03 87 5.000E+00 2.900E+01 3.000E+01 6.000E+00 7.678E+00 2.238E-13 7.6784E+00 4.626977E-04 88 5.833E+00 2.983E+01 3.500E+01 6.000E+00 8.990E+00 2.109E-13 8.9898E+00 1.246743E-04 89 2.778E-13 9.600E+01 0.000E+00 0.000E+00 0.000E+00 0.000E+00 0.0000E+00 1.000000E+00 90 8.333E-03 2.401E+01 1.000E-01 1.200E+01 1.624E-02 2.008E-13 1.6235E-02 9.838956E-01 91 2.083E-02 2.402E+01 2.500E-01 1.200E+01 4.160E-02 0.000E+00 4.1597E-02 9.592562E-01 92 4.167E-02 2.404E+01 5.000E-01 1.200E+01 8.643E-02 2.354E-14 8.6433E-02 9.171967E-01 93 8.333E-02 2.408E+01 1.000E+00 1.200E+01 1.850E-01 8.100E-13 1.8496E-01 8.311349E-01 94 1.250E-01 2.412E+01 1.500E+00 1.200E+01 2.940E-01 1.928E-13 2.9401E-01 7.452683E-01 95 1.667E-01 2.417E+01 2.000E+00 1.200E+01 4.122E-01 0.000E+00 4.1220E-01 6.621890E-01 96 2.500E-01 2.425E+01 3.000E+00 1.200E+01 6.714E-01 1.479E-13 6.7141E-01 5.109868E-01 97 3.333E-01 2.433E+01 4.000E+00 1.200E+01 9.548E-01 1.636E-13 9.5479E-01 3.848928E-01 98 4.167E-01 2.442E+01 5.000E+00 1.200E+01 1.256E+00 3.651E-14 1.2564E+00 2.846631E-01 99 5.000E-01 2.450E+01 6.000E+00 1.200E+01 1.572E+00 4.670E-14 1.5719E+00 2.076437E-01 100 5.833E-01 2.458E+01 7.000E+00 1.200E+01 1.898E+00 5.564E-14 1.8979E+00 1.498875E-01 101 6.667E-01 2.467E+01 8.000E+00 1.200E+01 2.232E+00 4.126E-14 2.2317E+00 1.073440E-01 102 7.500E-01 2.475E+01 9.000E+00 1.200E+01 2.572E+00 3.952E-13 2.5715E+00 7.641737E-02 103 8.333E-01 2.483E+01 1.000E+01 1.200E+01 2.916E+00 3.604E-13 2.9159E+00 5.415540E-02 104 1.042E+00 2.504E+01 1.250E+01 1.200E+01 3.790E+00 0.000E+00 3.7900E+00 2.259595E-02 105 1.250E+00 2.525E+01 1.500E+01 1.200E+01 4.675E+00 1.911E-13 4.6751E+00 9.324756E-03 106 1.458E+00 2.546E+01 1.750E+01 1.200E+01 5.566E+00 2.087E-14 5.5657E+00 3.827051E-03 107 1.667E+00 2.567E+01 2.000E+01 1.200E+01 6.459E+00 8.915E-14 6.4590E+00 1.566414E-03 108 2.083E+00 2.608E+01 2.500E+01 1.200E+01 8.249E+00 0.000E+00 8.2490E+00 2.615280E-04 109 2.500E+00 2.650E+01 3.000E+01 1.200E+01 1.004E+01 4.450E-13 1.0040E+01 4.359851E-05 110 2.917E+00 2.692E+01 3.500E+01 1.200E+01 1.183E+01 1.625E-13 1.1832E+01 7.265438E-06 111 2.778E-13 9.600E+01 0.000E+00 0.000E+00 0.000E+00 0.000E+00 0.0000E+00 1.000000E+00 112 3.333E-03 2.400E+01 1.000E-01 3.000E+01 1.624E-02 6.855E-13 1.6237E-02 9.838942E-01 113 8.333E-03 2.401E+01 2.500E-01 3.000E+01 4.162E-02 0.000E+00 4.1619E-02 9.592350E-01 114 1.667E-02 2.402E+01 5.000E-01 3.000E+01 8.661E-02 5.328E-14 8.6606E-02 9.170382E-01 115 3.333E-02 2.403E+01 1.000E+00 3.000E+01 1.863E-01 4.001E-13 1.8628E-01 8.300420E-01 116 5.000E-02 2.405E+01 1.500E+00 3.000E+01 2.982E-01 1.130E-13 2.9824E-01 7.421227E-01 117 6.667E-02 2.407E+01 2.000E+00 3.000E+01 4.218E-01 3.899E-13 4.2176E-01 6.558914E-01 118 1.000E-01 2.410E+01 3.000E+00 3.000E+01 7.008E-01 2.182E-14 7.0076E-01 4.962057E-01 119 1.333E-01 2.413E+01 4.000E+00 3.000E+01 1.018E+00 0.000E+00 1.0183E+00 3.612178E-01 120 1.667E-01 2.417E+01 5.000E+00 3.000E+01 1.370E+00 3.125E-14 1.3699E+00 2.541443E-01 121 2.000E-01 2.420E+01 6.000E+00 3.000E+01 1.752E+00 2.314E-13 1.7516E+00 1.734997E-01 122 2.333E-01 2.423E+01 7.000E+00 3.000E+01 2.160E+00 0.000E+00 2.1600E+00 1.153267E-01 123 2.667E-01 2.427E+01 8.000E+00 3.000E+01 2.592E+00 0.000E+00 2.5920E+00 7.486974E-02 124 3.000E-01 2.430E+01 9.000E+00 3.000E+01 3.045E+00 1.810E-13 3.0449E+00 4.759989E-02 125 3.333E-01 2.433E+01 1.000E+01 3.000E+01 3.516E+00 3.394E-13 3.5163E+00 2.970784E-02 126 4.167E-01 2.442E+01 1.250E+01 3.000E+01 4.762E+00 1.654E-13 4.7625E+00 8.544316E-03 127 5.000E-01 2.450E+01 1.500E+01 3.000E+01 6.085E+00 1.213E-13 6.0846E+00 2.277668E-03 128 5.833E-01 2.458E+01 1.750E+01 3.000E+01 7.463E+00 3.151E-13 7.4628E+00 5.740751E-04 129 6.667E-01 2.467E+01 2.000E+01 3.000E+01 8.882E+00 0.000E+00 8.8822E+00 1.388336E-04 130 8.333E-01 2.483E+01 2.500E+01 3.000E+01 1.180E+01 1.207E-13 1.1805E+01 7.469341E-06 131 1.000E+00 2.500E+01 3.000E+01 3.000E+01 1.480E+01 4.921E-14 1.4795E+01 3.754473E-07 132 1.167E+00 2.517E+01 3.500E+01 3.000E+01 1.782E+01 4.207E-14 1.7823E+01 1.818601E-08 133 2.778E-13 9.600E+01 0.000E+00 0.000E+00 0.000E+00 0.000E+00 0.0000E+00 1.000000E+00 134 1.302E-03 2.400E+01 1.000E-01 7.680E+01 1.624E-02 6.391E-13 1.6237E-02 9.838936E-01 135 3.255E-03 2.400E+01 2.500E-01 7.680E+01 4.163E-02 5.386E-14 4.1628E-02 9.592262E-01 136 6.510E-03 2.401E+01 5.000E-01 7.680E+01 8.668E-02 0.000E+00 8.6678E-02 9.169721E-01 137 1.302E-02 2.401E+01 1.000E+00 7.680E+01 1.868E-01 0.000E+00 1.8684E-01 8.295738E-01 138 1.953E-02 2.402E+01 1.500E+00 7.680E+01 3.001E-01 5.975E-13 3.0010E-01 7.407420E-01 139 2.604E-02 2.403E+01 2.000E+00 7.680E+01 4.261E-01 3.007E-13 4.2608E-01 6.530660E-01 140 3.906E-02 2.404E+01 3.000E+00 7.680E+01 7.147E-01 2.096E-13 7.1471E-01 4.893359E-01 141 5.208E-02 2.405E+01 4.000E+00 7.680E+01 1.050E+00 5.904E-14 1.0499E+00 3.499682E-01 142 6.510E-02 2.407E+01 5.000E+00 7.680E+01 1.429E+00 5.618E-14 1.4290E+00 2.395371E-01 143 7.812E-02 2.408E+01 6.000E+00 7.680E+01 1.850E+00 3.114E-13 1.8496E+00 1.572978E-01 144 9.115E-02 2.409E+01 7.000E+00 7.680E+01 2.309E+00 5.660E-14 2.3093E+00 9.933405E-02 145 1.042E-01 2.410E+01 8.000E+00 7.680E+01 2.806E+00 0.000E+00 2.8058E+00 6.045872E-02 146 1.172E-01 2.412E+01 9.000E+00 7.680E+01 3.337E+00 0.000E+00 3.3371E+00 3.553933E-02 147 1.302E-01 2.413E+01 1.000E+01 7.680E+01 3.901E+00 5.315E-13 3.9013E+00 2.021624E-02 148 1.628E-01 2.416E+01 1.250E+01 7.680E+01 5.443E+00 1.098E-13 5.4434E+00 4.324596E-03 149 1.953E-01 2.420E+01 1.500E+01 7.680E+01 7.153E+00 0.000E+00 7.1535E+00 7.821355E-04 150 2.279E-01 2.423E+01 1.750E+01 7.680E+01 9.009E+00 0.000E+00 9.0089E+00 1.223149E-04 151 2.604E-01 2.426E+01 2.000E+01 7.680E+01 1.099E+01 3.106E-13 1.0990E+01 1.686452E-05 152 3.255E-01 2.433E+01 2.500E+01 7.680E+01 1.527E+01 2.454E-13 1.5266E+01 2.344415E-07 153 3.906E-01 2.439E+01 3.000E+01 7.680E+01 1.987E+01 1.536E-13 1.9872E+01 2.342977E-09 154 4.557E-01 2.446E+01 3.500E+01 7.680E+01 2.473E+01 1.087E-13 2.4726E+01 1.826548E-11 ------------------------------------------------------------------------------------------------------ NOTE: SF=EXP{-(lethal residual damage + lethal mutations)}. QECK TABLE: Cell survival, corrected for repopulation effects, as a function of dose and dose rate. Cell kinetic parameters are: N(0)=F0*KAP*VOL=1.00000E+00, TCC=10.0000 h, Tpot=20.000 days. ===================================================================================================================== TSIM DOSE DOSE RATE - SURVIVING FRACTION - --------- EXPECTED NUMBER OF CELLS ----------- SIM ID (day) (Gy) (Gy/h) no repop repop N(t)/N(0) N(0)*S(D) N(t)*S(D) NSC(t) --------------------------------------------------------------------------------------------------------------------- 1 4.000E+00 0.000E+00 0.000E+00 1.0000E+00 1.0000E+00 1.0000E+00 1.0000E+00 1.0000E+00 1.0000E+00 2 1.007E+00 1.000E-01 6.000E-01 9.8394E-01 9.8394E-01 1.0000E+00 9.8394E-01 9.8394E-01 9.8394E-01 3 1.017E+00 2.500E-01 6.000E-01 9.5976E-01 9.5976E-01 1.0000E+00 9.5976E-01 9.5976E-01 9.5976E-01 4 1.035E+00 5.000E-01 6.000E-01 9.2015E-01 9.2015E-01 1.0000E+00 9.2015E-01 9.2015E-01 9.2015E-01 5 1.069E+00 1.000E+00 6.000E-01 8.4520E-01 8.4520E-01 1.0000E+00 8.4520E-01 8.4520E-01 8.4520E-01 6 1.104E+00 1.500E+00 6.000E-01 7.7626E-01 7.7626E-01 1.0000E+00 7.7626E-01 7.7626E-01 7.7626E-01 7 1.139E+00 2.000E+00 6.000E-01 7.1294E-01 7.1294E-01 1.0000E+00 7.1294E-01 7.1294E-01 7.1294E-01 8 1.208E+00 3.000E+00 6.000E-01 6.0137E-01 6.0137E-01 1.0000E+00 6.0137E-01 6.0137E-01 6.0137E-01 9 1.278E+00 4.000E+00 6.000E-01 5.0726E-01 5.0726E-01 1.0000E+00 5.0726E-01 5.0726E-01 5.0726E-01 10 1.347E+00 5.000E+00 6.000E-01 4.2788E-01 4.2788E-01 1.0000E+00 4.2788E-01 4.2788E-01 4.2788E-01 11 1.417E+00 6.000E+00 6.000E-01 3.6092E-01 3.6092E-01 1.0000E+00 3.6092E-01 3.6092E-01 3.6092E-01 12 1.486E+00 7.000E+00 6.000E-01 3.0443E-01 3.0443E-01 1.0000E+00 3.0443E-01 3.0443E-01 3.0443E-01 13 1.556E+00 8.000E+00 6.000E-01 2.5679E-01 2.5679E-01 1.0000E+00 2.5679E-01 2.5679E-01 2.5679E-01 14 1.625E+00 9.000E+00 6.000E-01 2.1661E-01 2.1661E-01 1.0000E+00 2.1661E-01 2.1661E-01 2.1661E-01 15 1.694E+00 1.000E+01 6.000E-01 1.8271E-01 1.8271E-01 1.0000E+00 1.8271E-01 1.8271E-01 1.8271E-01 16 1.868E+00 1.250E+01 6.000E-01 1.1939E-01 1.1939E-01 1.0000E+00 1.1939E-01 1.1939E-01 1.1939E-01 17 2.042E+00 1.500E+01 6.000E-01 7.8019E-02 7.8019E-02 1.0000E+00 7.8019E-02 7.8019E-02 7.8019E-02 18 2.215E+00 1.750E+01 6.000E-01 5.0983E-02 5.0983E-02 1.0000E+00 5.0983E-02 5.0983E-02 5.0983E-02 19 2.389E+00 2.000E+01 6.000E-01 3.3315E-02 3.3315E-02 1.0000E+00 3.3315E-02 3.3315E-02 3.3315E-02 20 2.736E+00 2.500E+01 6.000E-01 1.4226E-02 1.4226E-02 1.0000E+00 1.4226E-02 1.4226E-02 1.4226E-02 21 3.083E+00 3.000E+01 6.000E-01 6.0747E-03 6.0747E-03 1.0000E+00 6.0747E-03 6.0747E-03 6.0747E-03 22 3.431E+00 3.500E+01 6.000E-01 2.5940E-03 2.5940E-03 1.0000E+00 2.5940E-03 2.5940E-03 2.5940E-03 23 4.000E+00 0.000E+00 0.000E+00 1.0000E+00 1.0000E+00 1.0000E+00 1.0000E+00 1.0000E+00 1.0000E+00 24 1.003E+00 1.000E-01 1.200E+00 9.8392E-01 9.8392E-01 1.0000E+00 9.8392E-01 9.8392E-01 9.8392E-01 25 1.009E+00 2.500E-01 1.200E+00 9.5953E-01 9.5953E-01 1.0000E+00 9.5953E-01 9.5953E-01 9.5953E-01 26 1.017E+00 5.000E-01 1.200E+00 9.1898E-01 9.1898E-01 1.0000E+00 9.1898E-01 9.1898E-01 9.1898E-01 27 1.035E+00 1.000E+00 1.200E+00 8.4092E-01 8.4092E-01 1.0000E+00 8.4092E-01 8.4092E-01 8.4092E-01 28 1.052E+00 1.500E+00 1.200E+00 7.6859E-01 7.6859E-01 1.0000E+00 7.6859E-01 7.6859E-01 7.6859E-01 29 1.069E+00 2.000E+00 1.200E+00 7.0228E-01 7.0228E-01 1.0000E+00 7.0228E-01 7.0228E-01 7.0228E-01 30 1.104E+00 3.000E+00 1.200E+00 5.8620E-01 5.8620E-01 1.0000E+00 5.8620E-01 5.8620E-01 5.8620E-01 31 1.139E+00 4.000E+00 1.200E+00 4.8930E-01 4.8930E-01 1.0000E+00 4.8930E-01 4.8930E-01 4.8930E-01 32 1.174E+00 5.000E+00 1.200E+00 4.0841E-01 4.0841E-01 1.0000E+00 4.0841E-01 4.0841E-01 4.0841E-01 33 1.208E+00 6.000E+00 1.200E+00 3.4089E-01 3.4089E-01 1.0000E+00 3.4089E-01 3.4089E-01 3.4089E-01 34 1.243E+00 7.000E+00 1.200E+00 2.8454E-01 2.8454E-01 1.0000E+00 2.8454E-01 2.8454E-01 2.8454E-01 35 1.278E+00 8.000E+00 1.200E+00 2.3750E-01 2.3750E-01 1.0000E+00 2.3750E-01 2.3750E-01 2.3750E-01 36 1.312E+00 9.000E+00 1.200E+00 1.9824E-01 1.9824E-01 1.0000E+00 1.9824E-01 1.9824E-01 1.9824E-01 37 1.347E+00 1.000E+01 1.200E+00 1.6547E-01 1.6547E-01 1.0000E+00 1.6547E-01 1.6547E-01 1.6547E-01 38 1.434E+00 1.250E+01 1.200E+00 1.0532E-01 1.0532E-01 1.0000E+00 1.0532E-01 1.0532E-01 1.0532E-01 39 1.521E+00 1.500E+01 1.200E+00 6.7038E-02 6.7038E-02 1.0000E+00 6.7038E-02 6.7038E-02 6.7038E-02 40 1.608E+00 1.750E+01 1.200E+00 4.2671E-02 4.2671E-02 1.0000E+00 4.2671E-02 4.2671E-02 4.2671E-02 41 1.694E+00 2.000E+01 1.200E+00 2.7161E-02 2.7161E-02 1.0000E+00 2.7161E-02 2.7161E-02 2.7161E-02 42 1.868E+00 2.500E+01 1.200E+00 1.1004E-02 1.1004E-02 1.0000E+00 1.1004E-02 1.1004E-02 1.1004E-02 43 2.042E+00 3.000E+01 1.200E+00 4.4583E-03 4.4583E-03 1.0000E+00 4.4583E-03 4.4583E-03 4.4583E-03 44 2.215E+00 3.500E+01 1.200E+00 1.8063E-03 1.8063E-03 1.0000E+00 1.8063E-03 1.8063E-03 1.8063E-03 45 4.000E+00 0.000E+00 0.000E+00 1.0000E+00 1.0000E+00 1.0000E+00 1.0000E+00 1.0000E+00 1.0000E+00 46 1.001E+00 1.000E-01 3.000E+00 9.8390E-01 9.8390E-01 1.0000E+00 9.8390E-01 9.8390E-01 9.8390E-01 47 1.003E+00 2.500E-01 3.000E+00 9.5936E-01 9.5936E-01 1.0000E+00 9.5936E-01 9.5936E-01 9.5936E-01 48 1.007E+00 5.000E-01 3.000E+00 9.1790E-01 9.1790E-01 1.0000E+00 9.1790E-01 9.1790E-01 9.1790E-01 49 1.014E+00 1.000E+00 3.000E+00 8.3554E-01 8.3554E-01 1.0000E+00 8.3554E-01 8.3554E-01 8.3554E-01 50 1.021E+00 1.500E+00 3.000E+00 7.5685E-01 7.5685E-01 1.0000E+00 7.5685E-01 7.5685E-01 7.5685E-01 51 1.028E+00 2.000E+00 3.000E+00 6.8359E-01 6.8359E-01 1.0000E+00 6.8359E-01 6.8359E-01 6.8359E-01 52 1.042E+00 3.000E+00 3.000E+00 5.5523E-01 5.5523E-01 1.0000E+00 5.5523E-01 5.5523E-01 5.5523E-01 53 1.056E+00 4.000E+00 3.000E+00 4.4984E-01 4.4984E-01 1.0000E+00 4.4984E-01 4.4984E-01 4.4984E-01 54 1.069E+00 5.000E+00 3.000E+00 3.6414E-01 3.6414E-01 1.0000E+00 3.6414E-01 3.6414E-01 3.6414E-01 55 1.083E+00 6.000E+00 3.000E+00 2.9468E-01 2.9468E-01 1.0000E+00 2.9468E-01 2.9468E-01 2.9468E-01 56 1.097E+00 7.000E+00 3.000E+00 2.3844E-01 2.3844E-01 1.0000E+00 2.3844E-01 2.3844E-01 2.3844E-01 57 1.111E+00 8.000E+00 3.000E+00 1.9293E-01 1.9293E-01 1.0000E+00 1.9293E-01 1.9293E-01 1.9293E-01 58 1.125E+00 9.000E+00 3.000E+00 1.5611E-01 1.5611E-01 1.0000E+00 1.5611E-01 1.5611E-01 1.5611E-01 59 1.139E+00 1.000E+01 3.000E+00 1.2631E-01 1.2631E-01 1.0000E+00 1.2631E-01 1.2631E-01 1.2631E-01 60 1.174E+00 1.250E+01 3.000E+00 7.4383E-02 7.4383E-02 1.0000E+00 7.4383E-02 7.4383E-02 7.4383E-02 61 1.208E+00 1.500E+01 3.000E+00 4.3803E-02 4.3803E-02 1.0000E+00 4.3803E-02 4.3803E-02 4.3803E-02 62 1.243E+00 1.750E+01 3.000E+00 2.5795E-02 2.5795E-02 1.0000E+00 2.5795E-02 2.5795E-02 2.5795E-02 63 1.278E+00 2.000E+01 3.000E+00 1.5190E-02 1.5190E-02 1.0000E+00 1.5190E-02 1.5190E-02 1.5190E-02 64 1.347E+00 2.500E+01 3.000E+00 5.2679E-03 5.2679E-03 1.0000E+00 5.2679E-03 5.2679E-03 5.2679E-03 65 1.417E+00 3.000E+01 3.000E+00 1.8269E-03 1.8269E-03 1.0000E+00 1.8269E-03 1.8269E-03 1.8269E-03 66 1.486E+00 3.500E+01 3.000E+00 6.3354E-04 6.3354E-04 1.0000E+00 6.3354E-04 6.3354E-04 6.3354E-04 67 4.000E+00 0.000E+00 0.000E+00 1.0000E+00 1.0000E+00 1.0000E+00 1.0000E+00 1.0000E+00 1.0000E+00 68 1.001E+00 1.000E-01 6.000E+00 9.8390E-01 9.8390E-01 1.0000E+00 9.8390E-01 9.8390E-01 9.8390E-01 69 1.002E+00 2.500E-01 6.000E+00 9.5929E-01 9.5929E-01 1.0000E+00 9.5929E-01 9.5929E-01 9.5929E-01 70 1.003E+00 5.000E-01 6.000E+00 9.1745E-01 9.1745E-01 1.0000E+00 9.1745E-01 9.1745E-01 9.1745E-01 71 1.007E+00 1.000E+00 6.000E+00 8.3278E-01 8.3278E-01 1.0000E+00 8.3278E-01 8.3278E-01 8.3278E-01 72 1.010E+00 1.500E+00 6.000E+00 7.4981E-01 7.4981E-01 1.0000E+00 7.4981E-01 7.4981E-01 7.4981E-01 73 1.014E+00 2.000E+00 6.000E+00 6.7093E-01 6.7093E-01 1.0000E+00 6.7093E-01 6.7093E-01 6.7093E-01 74 1.021E+00 3.000E+00 6.000E+00 5.3020E-01 5.3020E-01 1.0000E+00 5.3020E-01 5.3020E-01 5.3020E-01 75 1.028E+00 4.000E+00 6.000E+00 4.1432E-01 4.1432E-01 1.0000E+00 4.1432E-01 4.1432E-01 4.1432E-01 76 1.035E+00 5.000E+00 6.000E+00 3.2165E-01 3.2165E-01 1.0000E+00 3.2165E-01 3.2165E-01 3.2165E-01 77 1.042E+00 6.000E+00 6.000E+00 2.4876E-01 2.4876E-01 1.0000E+00 2.4876E-01 2.4876E-01 2.4876E-01 78 1.049E+00 7.000E+00 6.000E+00 1.9196E-01 1.9196E-01 1.0000E+00 1.9196E-01 1.9196E-01 1.9196E-01 79 1.056E+00 8.000E+00 6.000E+00 1.4794E-01 1.4794E-01 1.0000E+00 1.4794E-01 1.4794E-01 1.4794E-01 80 1.062E+00 9.000E+00 6.000E+00 1.1393E-01 1.1393E-01 1.0000E+00 1.1393E-01 1.1393E-01 1.1393E-01 81 1.069E+00 1.000E+01 6.000E+00 8.7702E-02 8.7702E-02 1.0000E+00 8.7702E-02 8.7702E-02 8.7702E-02 82 1.087E+00 1.250E+01 6.000E+00 4.5554E-02 4.5554E-02 1.0000E+00 4.5554E-02 4.5554E-02 4.5554E-02 83 1.104E+00 1.500E+01 6.000E+00 2.3650E-02 2.3650E-02 1.0000E+00 2.3650E-02 2.3650E-02 2.3650E-02 84 1.122E+00 1.750E+01 6.000E+00 1.2277E-02 1.2277E-02 1.0000E+00 1.2277E-02 1.2277E-02 1.2277E-02 85 1.139E+00 2.000E+01 6.000E+00 6.3729E-03 6.3729E-03 1.0000E+00 6.3729E-03 6.3729E-03 6.3729E-03 86 1.174E+00 2.500E+01 6.000E+00 1.7172E-03 1.7172E-03 1.0000E+00 1.7172E-03 1.7172E-03 1.7172E-03 87 1.208E+00 3.000E+01 6.000E+00 4.6270E-04 4.6270E-04 1.0000E+00 4.6270E-04 4.6270E-04 4.6270E-04 88 1.243E+00 3.500E+01 6.000E+00 1.2467E-04 1.2467E-04 1.0000E+00 1.2467E-04 1.2467E-04 1.2467E-04 89 4.000E+00 0.000E+00 0.000E+00 1.0000E+00 1.0000E+00 1.0000E+00 1.0000E+00 1.0000E+00 1.0000E+00 90 1.000E+00 1.000E-01 1.200E+01 9.8390E-01 9.8390E-01 1.0000E+00 9.8390E-01 9.8390E-01 9.8390E-01 91 1.001E+00 2.500E-01 1.200E+01 9.5926E-01 9.5926E-01 1.0000E+00 9.5926E-01 9.5926E-01 9.5926E-01 92 1.002E+00 5.000E-01 1.200E+01 9.1720E-01 9.1720E-01 1.0000E+00 9.1720E-01 9.1720E-01 9.1720E-01 93 1.003E+00 1.000E+00 1.200E+01 8.3113E-01 8.3113E-01 1.0000E+00 8.3113E-01 8.3113E-01 8.3113E-01 94 1.005E+00 1.500E+00 1.200E+01 7.4527E-01 7.4527E-01 1.0000E+00 7.4527E-01 7.4527E-01 7.4527E-01 95 1.007E+00 2.000E+00 1.200E+01 6.6219E-01 6.6219E-01 1.0000E+00 6.6219E-01 6.6219E-01 6.6219E-01 96 1.010E+00 3.000E+00 1.200E+01 5.1099E-01 5.1099E-01 1.0000E+00 5.1099E-01 5.1099E-01 5.1099E-01 97 1.014E+00 4.000E+00 1.200E+01 3.8489E-01 3.8489E-01 1.0000E+00 3.8489E-01 3.8489E-01 3.8489E-01 98 1.017E+00 5.000E+00 1.200E+01 2.8466E-01 2.8466E-01 1.0000E+00 2.8466E-01 2.8466E-01 2.8466E-01 99 1.021E+00 6.000E+00 1.200E+01 2.0764E-01 2.0764E-01 1.0000E+00 2.0764E-01 2.0764E-01 2.0764E-01 100 1.024E+00 7.000E+00 1.200E+01 1.4989E-01 1.4989E-01 1.0000E+00 1.4989E-01 1.4989E-01 1.4989E-01 101 1.028E+00 8.000E+00 1.200E+01 1.0734E-01 1.0734E-01 1.0000E+00 1.0734E-01 1.0734E-01 1.0734E-01 102 1.031E+00 9.000E+00 1.200E+01 7.6417E-02 7.6417E-02 1.0000E+00 7.6417E-02 7.6417E-02 7.6417E-02 103 1.035E+00 1.000E+01 1.200E+01 5.4155E-02 5.4155E-02 1.0000E+00 5.4155E-02 5.4155E-02 5.4155E-02 104 1.043E+00 1.250E+01 1.200E+01 2.2596E-02 2.2596E-02 1.0000E+00 2.2596E-02 2.2596E-02 2.2596E-02 105 1.052E+00 1.500E+01 1.200E+01 9.3248E-03 9.3248E-03 1.0000E+00 9.3248E-03 9.3248E-03 9.3248E-03 106 1.061E+00 1.750E+01 1.200E+01 3.8271E-03 3.8271E-03 1.0000E+00 3.8271E-03 3.8271E-03 3.8271E-03 107 1.069E+00 2.000E+01 1.200E+01 1.5664E-03 1.5664E-03 1.0000E+00 1.5664E-03 1.5664E-03 1.5664E-03 108 1.087E+00 2.500E+01 1.200E+01 2.6153E-04 2.6153E-04 1.0000E+00 2.6153E-04 2.6153E-04 2.6153E-04 109 1.104E+00 3.000E+01 1.200E+01 4.3599E-05 4.3599E-05 1.0000E+00 4.3599E-05 4.3599E-05 4.3599E-05 110 1.122E+00 3.500E+01 1.200E+01 7.2654E-06 7.2654E-06 1.0000E+00 7.2654E-06 7.2654E-06 7.2654E-06 111 4.000E+00 0.000E+00 0.000E+00 1.0000E+00 1.0000E+00 1.0000E+00 1.0000E+00 1.0000E+00 1.0000E+00 112 1.000E+00 1.000E-01 3.000E+01 9.8389E-01 9.8389E-01 1.0000E+00 9.8389E-01 9.8389E-01 9.8389E-01 113 1.000E+00 2.500E-01 3.000E+01 9.5923E-01 9.5923E-01 1.0000E+00 9.5923E-01 9.5923E-01 9.5923E-01 114 1.001E+00 5.000E-01 3.000E+01 9.1704E-01 9.1704E-01 1.0000E+00 9.1704E-01 9.1704E-01 9.1704E-01 115 1.001E+00 1.000E+00 3.000E+01 8.3004E-01 8.3004E-01 1.0000E+00 8.3004E-01 8.3004E-01 8.3004E-01 116 1.002E+00 1.500E+00 3.000E+01 7.4212E-01 7.4212E-01 1.0000E+00 7.4212E-01 7.4212E-01 7.4212E-01 117 1.003E+00 2.000E+00 3.000E+01 6.5589E-01 6.5589E-01 1.0000E+00 6.5589E-01 6.5589E-01 6.5589E-01 118 1.004E+00 3.000E+00 3.000E+01 4.9621E-01 4.9621E-01 1.0000E+00 4.9621E-01 4.9621E-01 4.9621E-01 119 1.006E+00 4.000E+00 3.000E+01 3.6122E-01 3.6122E-01 1.0000E+00 3.6122E-01 3.6122E-01 3.6122E-01 120 1.007E+00 5.000E+00 3.000E+01 2.5414E-01 2.5414E-01 1.0000E+00 2.5414E-01 2.5414E-01 2.5414E-01 121 1.008E+00 6.000E+00 3.000E+01 1.7350E-01 1.7350E-01 1.0000E+00 1.7350E-01 1.7350E-01 1.7350E-01 122 1.010E+00 7.000E+00 3.000E+01 1.1533E-01 1.1533E-01 1.0000E+00 1.1533E-01 1.1533E-01 1.1533E-01 123 1.011E+00 8.000E+00 3.000E+01 7.4870E-02 7.4870E-02 1.0000E+00 7.4870E-02 7.4870E-02 7.4870E-02 124 1.012E+00 9.000E+00 3.000E+01 4.7600E-02 4.7600E-02 1.0000E+00 4.7600E-02 4.7600E-02 4.7600E-02 125 1.014E+00 1.000E+01 3.000E+01 2.9708E-02 2.9708E-02 1.0000E+00 2.9708E-02 2.9708E-02 2.9708E-02 126 1.017E+00 1.250E+01 3.000E+01 8.5443E-03 8.5443E-03 1.0000E+00 8.5443E-03 8.5443E-03 8.5443E-03 127 1.021E+00 1.500E+01 3.000E+01 2.2777E-03 2.2777E-03 1.0000E+00 2.2777E-03 2.2777E-03 2.2777E-03 128 1.024E+00 1.750E+01 3.000E+01 5.7408E-04 5.7408E-04 1.0000E+00 5.7408E-04 5.7408E-04 5.7408E-04 129 1.028E+00 2.000E+01 3.000E+01 1.3883E-04 1.3883E-04 1.0000E+00 1.3883E-04 1.3883E-04 1.3883E-04 130 1.035E+00 2.500E+01 3.000E+01 7.4693E-06 7.4693E-06 1.0000E+00 7.4693E-06 7.4693E-06 7.4693E-06 131 1.042E+00 3.000E+01 3.000E+01 3.7545E-07 3.7545E-07 1.0000E+00 3.7545E-07 3.7545E-07 3.7545E-07 132 1.049E+00 3.500E+01 3.000E+01 1.8186E-08 1.8186E-08 1.0000E+00 1.8186E-08 1.8186E-08 1.8186E-08 133 4.000E+00 0.000E+00 0.000E+00 1.0000E+00 1.0000E+00 1.0000E+00 1.0000E+00 1.0000E+00 1.0000E+00 134 1.000E+00 1.000E-01 7.680E+01 9.8389E-01 9.8389E-01 1.0000E+00 9.8389E-01 9.8389E-01 9.8389E-01 135 1.000E+00 2.500E-01 7.680E+01 9.5923E-01 9.5923E-01 1.0000E+00 9.5923E-01 9.5923E-01 9.5923E-01 136 1.000E+00 5.000E-01 7.680E+01 9.1697E-01 9.1697E-01 1.0000E+00 9.1697E-01 9.1697E-01 9.1697E-01 137 1.001E+00 1.000E+00 7.680E+01 8.2957E-01 8.2957E-01 1.0000E+00 8.2957E-01 8.2957E-01 8.2957E-01 138 1.001E+00 1.500E+00 7.680E+01 7.4074E-01 7.4074E-01 1.0000E+00 7.4074E-01 7.4074E-01 7.4074E-01 139 1.001E+00 2.000E+00 7.680E+01 6.5307E-01 6.5307E-01 1.0000E+00 6.5307E-01 6.5307E-01 6.5307E-01 140 1.002E+00 3.000E+00 7.680E+01 4.8934E-01 4.8934E-01 1.0000E+00 4.8934E-01 4.8934E-01 4.8934E-01 141 1.002E+00 4.000E+00 7.680E+01 3.4997E-01 3.4997E-01 1.0000E+00 3.4997E-01 3.4997E-01 3.4997E-01 142 1.003E+00 5.000E+00 7.680E+01 2.3954E-01 2.3954E-01 1.0000E+00 2.3954E-01 2.3954E-01 2.3954E-01 143 1.003E+00 6.000E+00 7.680E+01 1.5730E-01 1.5730E-01 1.0000E+00 1.5730E-01 1.5730E-01 1.5730E-01 144 1.004E+00 7.000E+00 7.680E+01 9.9334E-02 9.9334E-02 1.0000E+00 9.9334E-02 9.9334E-02 9.9334E-02 145 1.004E+00 8.000E+00 7.680E+01 6.0459E-02 6.0459E-02 1.0000E+00 6.0459E-02 6.0459E-02 6.0459E-02 146 1.005E+00 9.000E+00 7.680E+01 3.5539E-02 3.5539E-02 1.0000E+00 3.5539E-02 3.5539E-02 3.5539E-02 147 1.005E+00 1.000E+01 7.680E+01 2.0216E-02 2.0216E-02 1.0000E+00 2.0216E-02 2.0216E-02 2.0216E-02 148 1.007E+00 1.250E+01 7.680E+01 4.3246E-03 4.3246E-03 1.0000E+00 4.3246E-03 4.3246E-03 4.3246E-03 149 1.008E+00 1.500E+01 7.680E+01 7.8214E-04 7.8214E-04 1.0000E+00 7.8214E-04 7.8214E-04 7.8214E-04 150 1.009E+00 1.750E+01 7.680E+01 1.2231E-04 1.2231E-04 1.0000E+00 1.2231E-04 1.2231E-04 1.2231E-04 151 1.011E+00 2.000E+01 7.680E+01 1.6865E-05 1.6865E-05 1.0000E+00 1.6865E-05 1.6865E-05 1.6865E-05 152 1.014E+00 2.500E+01 7.680E+01 2.3444E-07 2.3444E-07 1.0000E+00 2.3444E-07 2.3444E-07 2.3444E-07 153 1.016E+00 3.000E+01 7.680E+01 2.3430E-09 2.3430E-09 1.0000E+00 2.3430E-09 2.3430E-09 2.3430E-09 154 1.019E+00 3.500E+01 7.680E+01 1.8265E-11 1.8265E-11 1.0000E+00 1.8265E-11 1.8265E-11 1.8265E-11 --------------------------------------------------------------------------------------------------------------------- NOTE: N(0) is the initial number of cells (time=0 day), N(t) is the expected number of unirradiated (control) cells at TSIM, i.e., N(t)=N(0)*EXP[LN(2)*TSIM/TPOT]. The surviving fraction S(D) is the expected number of cells, per irradiated cell, that has not sustained lethal DNA damage (no corrections for repopulation effects). NSC(t) is the expected number of cells that survive irradiation, including repopulation effects (recommended method). The product N(t)*S(D) is an alternate method of estimating the surviving fraction with repopulation effects. DFAR TABLE: Mutagenesis and the induction of enhanced genetic instability (GI). Key GI model parameters are: (1-FRDL)=0.0%, NCM=1, NCG=1, and NCG*PGH*PGA=4.250E-06. ====================================================================================================== Dose Dose Rate -- NON-LETHAL MUTATIONS PER CELL -- **** PROBABILITY PER CELL **** SIM ID (Gy) (Gy/h) Mutations Residual Total AGF EGI EGI/SF ------------------------------------------------------------------------------------------------------ 1 0.000E+00 0.000E+00 0.000E+00 0.00E+00 0.00000E+00 0.000E+00 0.000E+00 0.000E+00 2 1.000E-01 6.000E-01 8.594E-01 0.00E+00 8.59431E-01 3.594E-06 3.594E-06 3.653E-06 3 2.500E-01 6.000E-01 2.150E+00 0.00E+00 2.14955E+00 8.768E-06 8.768E-06 9.136E-06 4 5.000E-01 6.000E-01 4.301E+00 0.00E+00 4.30089E+00 1.682E-05 1.682E-05 1.828E-05 5 1.000E+00 6.000E-01 8.605E+00 0.00E+00 8.60465E+00 3.091E-05 3.091E-05 3.657E-05 6 1.500E+00 6.000E-01 1.291E+01 0.00E+00 1.29086E+01 4.259E-05 4.259E-05 5.486E-05 7 2.000E+00 6.000E-01 1.721E+01 0.00E+00 1.72126E+01 5.215E-05 5.215E-05 7.315E-05 8 3.000E+00 6.000E-01 2.582E+01 0.00E+00 2.58206E+01 6.599E-05 6.599E-05 1.097E-04 9 4.000E+00 6.000E-01 3.443E+01 0.00E+00 3.44285E+01 7.422E-05 7.422E-05 1.463E-04 10 5.000E+00 6.000E-01 4.304E+01 0.00E+00 4.30365E+01 7.825E-05 7.825E-05 1.829E-04 11 6.000E+00 6.000E-01 5.164E+01 0.00E+00 5.16445E+01 7.921E-05 7.921E-05 2.195E-04 12 7.000E+00 6.000E-01 6.025E+01 0.00E+00 6.02525E+01 7.795E-05 7.795E-05 2.560E-04 13 8.000E+00 6.000E-01 6.886E+01 0.00E+00 6.88604E+01 7.514E-05 7.514E-05 2.926E-04 14 9.000E+00 6.000E-01 7.747E+01 0.00E+00 7.74684E+01 7.130E-05 7.130E-05 3.292E-04 15 1.000E+01 6.000E-01 8.608E+01 0.00E+00 8.60764E+01 6.683E-05 6.683E-05 3.658E-04 16 1.250E+01 6.000E-01 1.076E+02 0.00E+00 1.07596E+02 5.458E-05 5.458E-05 4.572E-04 17 1.500E+01 6.000E-01 1.291E+02 0.00E+00 1.29116E+02 4.280E-05 4.280E-05 5.486E-04 18 1.750E+01 6.000E-01 1.506E+02 0.00E+00 1.50636E+02 3.263E-05 3.263E-05 6.400E-04 19 2.000E+01 6.000E-01 1.722E+02 0.00E+00 1.72156E+02 2.437E-05 2.437E-05 7.314E-04 20 2.500E+01 6.000E-01 2.152E+02 0.00E+00 2.15196E+02 1.300E-05 1.300E-05 9.142E-04 21 3.000E+01 6.000E-01 2.582E+02 0.00E+00 2.58236E+02 6.663E-06 6.663E-06 1.097E-03 22 3.500E+01 6.000E-01 3.013E+02 0.00E+00 3.01276E+02 3.319E-06 3.319E-06 1.280E-03 23 0.000E+00 0.000E+00 0.000E+00 0.00E+00 0.00000E+00 0.000E+00 0.000E+00 0.000E+00 24 1.000E-01 1.200E+00 8.595E-01 0.00E+00 8.59464E-01 3.594E-06 3.594E-06 3.653E-06 25 2.500E-01 1.200E+00 2.150E+00 0.00E+00 2.14995E+00 8.767E-06 8.767E-06 9.137E-06 26 5.000E-01 1.200E+00 4.303E+00 0.00E+00 4.30299E+00 1.681E-05 1.681E-05 1.829E-05 27 1.000E+00 1.200E+00 8.613E+00 0.00E+00 8.61310E+00 3.078E-05 3.078E-05 3.661E-05 28 1.500E+00 1.200E+00 1.293E+01 0.00E+00 1.29251E+01 4.222E-05 4.222E-05 5.493E-05 29 2.000E+00 1.200E+00 1.724E+01 0.00E+00 1.72376E+01 5.145E-05 5.145E-05 7.326E-05 30 3.000E+00 1.200E+00 2.586E+01 0.00E+00 2.58630E+01 6.443E-05 6.443E-05 1.099E-04 31 4.000E+00 1.200E+00 3.449E+01 0.00E+00 3.44884E+01 7.171E-05 7.171E-05 1.466E-04 32 5.000E+00 1.200E+00 4.311E+01 0.00E+00 4.31139E+01 7.483E-05 7.483E-05 1.832E-04 33 6.000E+00 1.200E+00 5.174E+01 0.00E+00 5.17393E+01 7.495E-05 7.495E-05 2.199E-04 34 7.000E+00 1.200E+00 6.036E+01 0.00E+00 6.03647E+01 7.299E-05 7.299E-05 2.565E-04 35 8.000E+00 1.200E+00 6.899E+01 0.00E+00 6.89901E+01 6.963E-05 6.963E-05 2.932E-04 36 9.000E+00 1.200E+00 7.762E+01 0.00E+00 7.76156E+01 6.538E-05 6.538E-05 3.298E-04 37 1.000E+01 1.200E+00 8.624E+01 0.00E+00 8.62410E+01 6.064E-05 6.064E-05 3.665E-04 38 1.250E+01 1.200E+00 1.078E+02 0.00E+00 1.07805E+02 4.824E-05 4.824E-05 4.581E-04 39 1.500E+01 1.200E+00 1.294E+02 0.00E+00 1.29368E+02 3.685E-05 3.685E-05 5.497E-04 40 1.750E+01 1.200E+00 1.509E+02 0.00E+00 1.50932E+02 2.736E-05 2.736E-05 6.413E-04 41 2.000E+01 1.200E+00 1.725E+02 0.00E+00 1.72495E+02 1.990E-05 1.990E-05 7.328E-04 42 2.500E+01 1.200E+00 2.156E+02 0.00E+00 2.15622E+02 1.008E-05 1.008E-05 9.160E-04 43 3.000E+01 1.200E+00 2.587E+02 0.00E+00 2.58749E+02 4.900E-06 4.900E-06 1.099E-03 44 3.500E+01 1.200E+00 3.019E+02 0.00E+00 3.01877E+02 2.316E-06 2.316E-06 1.282E-03 45 0.000E+00 0.000E+00 0.000E+00 0.00E+00 0.00000E+00 0.000E+00 0.000E+00 0.000E+00 46 1.000E-01 3.000E+00 8.595E-01 0.00E+00 8.59486E-01 3.594E-06 3.594E-06 3.653E-06 47 2.500E-01 3.000E+00 2.150E+00 0.00E+00 2.15025E+00 8.767E-06 8.767E-06 9.139E-06 48 5.000E-01 3.000E+00 4.305E+00 0.00E+00 4.30495E+00 1.679E-05 1.679E-05 1.830E-05 49 1.000E+00 3.000E+00 8.624E+00 0.00E+00 8.62378E+00 3.062E-05 3.062E-05 3.665E-05 50 1.500E+00 3.000E+00 1.295E+01 0.00E+00 1.29508E+01 4.166E-05 4.166E-05 5.504E-05 51 2.000E+00 3.000E+00 1.728E+01 0.00E+00 1.72825E+01 5.021E-05 5.021E-05 7.345E-05 52 3.000E+00 3.000E+00 2.595E+01 0.00E+00 2.59533E+01 6.124E-05 6.124E-05 1.103E-04 53 4.000E+00 3.000E+00 3.463E+01 0.00E+00 3.46282E+01 6.620E-05 6.620E-05 1.472E-04 54 5.000E+00 3.000E+00 4.330E+01 0.00E+00 4.33045E+01 6.701E-05 6.701E-05 1.840E-04 55 6.000E+00 3.000E+00 5.198E+01 0.00E+00 5.19813E+01 6.509E-05 6.509E-05 2.209E-04 56 7.000E+00 3.000E+00 6.066E+01 0.00E+00 6.06583E+01 6.146E-05 6.146E-05 2.578E-04 57 8.000E+00 3.000E+00 6.934E+01 0.00E+00 6.93353E+01 5.684E-05 5.684E-05 2.946E-04 58 9.000E+00 3.000E+00 7.801E+01 0.00E+00 7.80124E+01 5.175E-05 5.175E-05 3.315E-04 59 1.000E+01 3.000E+00 8.669E+01 0.00E+00 8.66895E+01 4.653E-05 4.653E-05 3.684E-04 60 1.250E+01 3.000E+00 1.084E+02 0.00E+00 1.08382E+02 3.425E-05 3.425E-05 4.605E-04 61 1.500E+01 3.000E+00 1.301E+02 0.00E+00 1.30075E+02 2.421E-05 2.421E-05 5.527E-04 62 1.750E+01 3.000E+00 1.518E+02 0.00E+00 1.51768E+02 1.663E-05 1.663E-05 6.448E-04 63 2.000E+01 3.000E+00 1.735E+02 0.00E+00 1.73460E+02 1.119E-05 1.119E-05 7.369E-04 64 2.500E+01 3.000E+00 2.168E+02 0.00E+00 2.16846E+02 4.853E-06 4.853E-06 9.212E-04 65 3.000E+01 3.000E+00 2.602E+02 0.00E+00 2.60231E+02 2.019E-06 2.019E-06 1.105E-03 66 3.500E+01 3.000E+00 3.036E+02 0.00E+00 3.03616E+02 8.170E-07 8.170E-07 1.290E-03 67 0.000E+00 0.000E+00 0.000E+00 0.00E+00 0.00000E+00 0.000E+00 0.000E+00 0.000E+00 68 1.000E-01 6.000E+00 8.595E-01 0.00E+00 8.59494E-01 3.594E-06 3.594E-06 3.653E-06 69 2.500E-01 6.000E+00 2.150E+00 0.00E+00 2.15036E+00 8.767E-06 8.767E-06 9.139E-06 70 5.000E-01 6.000E+00 4.306E+00 0.00E+00 4.30578E+00 1.679E-05 1.679E-05 1.830E-05 71 1.000E+00 6.000E+00 8.629E+00 0.00E+00 8.62929E+00 3.054E-05 3.054E-05 3.667E-05 72 1.500E+00 6.000E+00 1.297E+01 0.00E+00 1.29663E+01 4.132E-05 4.132E-05 5.511E-05 73 2.000E+00 6.000E+00 1.731E+01 0.00E+00 1.73137E+01 4.937E-05 4.937E-05 7.358E-05 74 3.000E+00 6.000E+00 2.603E+01 0.00E+00 2.60301E+01 5.865E-05 5.865E-05 1.106E-04 75 4.000E+00 6.000E+00 3.477E+01 0.00E+00 3.47651E+01 6.121E-05 6.121E-05 1.477E-04 76 5.000E+00 6.000E+00 4.351E+01 0.00E+00 4.35109E+01 5.947E-05 5.947E-05 1.849E-04 77 6.000E+00 6.000E+00 5.226E+01 0.00E+00 5.22630E+01 5.525E-05 5.525E-05 2.221E-04 78 7.000E+00 6.000E+00 6.102E+01 0.00E+00 6.10188E+01 4.978E-05 4.978E-05 2.593E-04 79 8.000E+00 6.000E+00 6.978E+01 0.00E+00 6.97767E+01 4.387E-05 4.387E-05 2.965E-04 80 9.000E+00 6.000E+00 7.854E+01 0.00E+00 7.85359E+01 3.802E-05 3.802E-05 3.337E-04 81 1.000E+01 6.000E+00 8.730E+01 0.00E+00 8.72957E+01 3.253E-05 3.253E-05 3.709E-04 82 1.250E+01 6.000E+00 1.092E+02 0.00E+00 1.09197E+02 2.114E-05 2.114E-05 4.640E-04 83 1.500E+01 6.000E+00 1.311E+02 0.00E+00 1.31099E+02 1.317E-05 1.317E-05 5.570E-04 84 1.750E+01 6.000E+00 1.530E+02 0.00E+00 1.53001E+02 7.981E-06 7.981E-06 6.500E-04 85 2.000E+01 6.000E+00 1.749E+02 0.00E+00 1.74903E+02 4.735E-06 4.735E-06 7.431E-04 86 2.500E+01 6.000E+00 2.187E+02 0.00E+00 2.18707E+02 1.595E-06 1.595E-06 9.291E-04 87 3.000E+01 6.000E+00 2.625E+02 0.00E+00 2.62512E+02 5.159E-07 5.159E-07 1.115E-03 88 3.500E+01 6.000E+00 3.063E+02 0.00E+00 3.06316E+02 1.622E-07 1.622E-07 1.301E-03 89 0.000E+00 0.000E+00 0.000E+00 0.00E+00 0.00000E+00 0.000E+00 0.000E+00 0.000E+00 90 1.000E-01 1.200E+01 8.595E-01 0.00E+00 8.59498E-01 3.594E-06 3.594E-06 3.653E-06 91 2.500E-01 1.200E+01 2.150E+00 0.00E+00 2.15042E+00 8.767E-06 8.767E-06 9.139E-06 92 5.000E-01 1.200E+01 4.306E+00 0.00E+00 4.30624E+00 1.679E-05 1.679E-05 1.830E-05 93 1.000E+00 1.200E+01 8.633E+00 0.00E+00 8.63260E+00 3.049E-05 3.049E-05 3.669E-05 94 1.500E+00 1.200E+01 1.298E+01 0.00E+00 1.29764E+01 4.110E-05 4.110E-05 5.515E-05 95 2.000E+00 1.200E+01 1.734E+01 0.00E+00 1.73355E+01 4.879E-05 4.879E-05 7.367E-05 96 3.000E+00 1.200E+01 2.609E+01 0.00E+00 2.60916E+01 5.666E-05 5.666E-05 1.109E-04 97 4.000E+00 1.200E+01 3.489E+01 0.00E+00 3.48878E+01 5.706E-05 5.706E-05 1.483E-04 98 5.000E+00 1.200E+01 4.371E+01 0.00E+00 4.37143E+01 5.288E-05 5.288E-05 1.858E-04 99 6.000E+00 1.200E+01 5.256E+01 0.00E+00 5.25638E+01 4.638E-05 4.638E-05 2.234E-04 100 7.000E+00 1.200E+01 6.143E+01 0.00E+00 6.14306E+01 3.913E-05 3.913E-05 2.610E-04 101 8.000E+00 1.200E+01 7.031E+01 0.00E+00 7.03106E+01 3.207E-05 3.207E-05 2.988E-04 102 9.000E+00 1.200E+01 7.920E+01 0.00E+00 7.92004E+01 2.572E-05 2.572E-05 3.365E-04 103 1.000E+01 1.200E+01 8.810E+01 0.00E+00 8.80977E+01 2.027E-05 2.027E-05 3.743E-04 104 1.250E+01 1.200E+01 1.104E+02 0.00E+00 1.10363E+02 1.060E-05 1.060E-05 4.689E-04 105 1.500E+01 1.200E+01 1.326E+02 0.00E+00 1.32646E+02 5.255E-06 5.255E-06 5.636E-04 106 1.750E+01 1.200E+01 1.549E+02 0.00E+00 1.54939E+02 2.519E-06 2.519E-06 6.583E-04 107 2.000E+01 1.200E+01 1.772E+02 0.00E+00 1.77235E+02 1.179E-06 1.179E-06 7.530E-04 108 2.500E+01 1.200E+01 2.218E+02 0.00E+00 2.21835E+02 2.465E-07 2.465E-07 9.424E-04 109 3.000E+01 1.200E+01 2.664E+02 0.00E+00 2.66436E+02 4.934E-08 4.934E-08 1.132E-03 110 3.500E+01 1.200E+01 3.110E+02 0.00E+00 3.11039E+02 9.598E-09 9.598E-09 1.321E-03 111 0.000E+00 0.000E+00 0.000E+00 0.00E+00 0.00000E+00 0.000E+00 0.000E+00 0.000E+00 112 1.000E-01 3.000E+01 8.595E-01 0.00E+00 8.59500E-01 3.594E-06 3.594E-06 3.653E-06 113 2.500E-01 3.000E+01 2.150E+00 0.00E+00 2.15046E+00 8.767E-06 8.767E-06 9.139E-06 114 5.000E-01 3.000E+01 4.307E+00 0.00E+00 4.30652E+00 1.678E-05 1.678E-05 1.830E-05 115 1.000E+00 3.000E+01 8.635E+00 0.00E+00 8.63479E+00 3.046E-05 3.046E-05 3.670E-05 116 1.500E+00 3.000E+01 1.298E+01 0.00E+00 1.29835E+01 4.095E-05 4.095E-05 5.518E-05 117 2.000E+00 3.000E+01 1.735E+01 0.00E+00 1.73514E+01 4.837E-05 4.837E-05 7.374E-05 118 3.000E+00 3.000E+01 2.614E+01 0.00E+00 2.61405E+01 5.512E-05 5.512E-05 1.111E-04 119 4.000E+00 3.000E+01 3.499E+01 0.00E+00 3.49936E+01 5.372E-05 5.372E-05 1.487E-04 120 5.000E+00 3.000E+01 4.390E+01 0.00E+00 4.39033E+01 4.742E-05 4.742E-05 1.866E-04 121 6.000E+00 3.000E+01 5.286E+01 0.00E+00 5.28632E+01 3.898E-05 3.898E-05 2.246E-04 122 7.000E+00 3.000E+01 6.187E+01 0.00E+00 6.18674E+01 3.032E-05 3.032E-05 2.629E-04 123 8.000E+00 3.000E+01 7.091E+01 0.00E+00 7.09108E+01 2.256E-05 2.256E-05 3.013E-04 124 9.000E+00 3.000E+01 7.999E+01 0.00E+00 7.99890E+01 1.618E-05 1.618E-05 3.399E-04 125 1.000E+01 3.000E+01 8.910E+01 0.00E+00 8.90978E+01 1.125E-05 1.125E-05 3.786E-04 126 1.250E+01 3.000E+01 1.120E+02 0.00E+00 1.11982E+02 4.065E-06 4.065E-06 4.758E-04 127 1.500E+01 3.000E+01 1.350E+02 0.00E+00 1.34993E+02 1.306E-06 1.306E-06 5.736E-04 128 1.750E+01 3.000E+01 1.581E+02 0.00E+00 1.58096E+02 3.856E-07 3.856E-07 6.717E-04 129 2.000E+01 3.000E+01 1.813E+02 0.00E+00 1.81268E+02 1.069E-07 1.069E-07 7.701E-04 130 2.500E+01 3.000E+01 2.277E+02 0.00E+00 2.27750E+02 7.226E-09 7.226E-09 9.675E-04 131 3.000E+01 3.000E+01 2.743E+02 0.00E+00 2.74344E+02 4.375E-10 4.375E-10 1.165E-03 132 3.500E+01 3.000E+01 3.210E+02 0.00E+00 3.21000E+02 2.479E-11 2.479E-11 1.363E-03 133 0.000E+00 0.000E+00 0.000E+00 0.00E+00 0.00000E+00 0.000E+00 0.000E+00 0.000E+00 134 1.000E-01 7.680E+01 8.595E-01 0.00E+00 8.59501E-01 3.594E-06 3.594E-06 3.653E-06 135 2.500E-01 7.680E+01 2.150E+00 0.00E+00 2.15047E+00 8.767E-06 8.767E-06 9.139E-06 136 5.000E-01 7.680E+01 4.307E+00 0.00E+00 4.30664E+00 1.678E-05 1.678E-05 1.830E-05 137 1.000E+00 7.680E+01 8.636E+00 0.00E+00 8.63573E+00 3.045E-05 3.045E-05 3.670E-05 138 1.500E+00 7.680E+01 1.299E+01 0.00E+00 1.29866E+01 4.088E-05 4.088E-05 5.519E-05 139 2.000E+00 7.680E+01 1.736E+01 0.00E+00 1.73586E+01 4.818E-05 4.818E-05 7.377E-05 140 3.000E+00 7.680E+01 2.616E+01 0.00E+00 2.61638E+01 5.441E-05 5.441E-05 1.112E-04 141 4.000E+00 7.680E+01 3.505E+01 0.00E+00 3.50464E+01 5.212E-05 5.212E-05 1.489E-04 142 5.000E+00 7.680E+01 4.400E+01 0.00E+00 4.40020E+01 4.479E-05 4.479E-05 1.870E-04 143 6.000E+00 7.680E+01 5.303E+01 0.00E+00 5.30267E+01 3.545E-05 3.545E-05 2.253E-04 144 7.000E+00 7.680E+01 6.212E+01 0.00E+00 6.21163E+01 2.622E-05 2.622E-05 2.640E-04 145 8.000E+00 7.680E+01 7.127E+01 0.00E+00 7.12673E+01 1.831E-05 1.831E-05 3.028E-04 146 9.000E+00 7.680E+01 8.048E+01 0.00E+00 8.04761E+01 1.215E-05 1.215E-05 3.420E-04 147 1.000E+01 7.680E+01 8.974E+01 0.00E+00 8.97396E+01 7.709E-06 7.709E-06 3.813E-04 148 1.250E+01 7.680E+01 1.131E+02 0.00E+00 1.13117E+02 2.079E-06 2.079E-06 4.806E-04 149 1.500E+01 7.680E+01 1.368E+02 0.00E+00 1.36774E+02 4.545E-07 4.545E-07 5.811E-04 150 1.750E+01 7.680E+01 1.607E+02 0.00E+00 1.60673E+02 8.350E-08 8.350E-08 6.826E-04 151 2.000E+01 7.680E+01 1.848E+02 0.00E+00 1.84781E+02 1.324E-08 1.324E-08 7.850E-04 152 2.500E+01 7.680E+01 2.335E+02 0.00E+00 2.33516E+02 2.326E-10 2.326E-10 9.920E-04 153 3.000E+01 7.680E+01 2.828E+02 0.00E+00 2.82800E+02 2.814E-12 2.814E-12 1.201E-03 154 3.500E+01 7.680E+01 3.325E+02 0.00E+00 3.32496E+02 2.579E-14 2.579E-14 1.412E-03 ------------------------------------------------------------------------------------------------------ AGF: function or expression of at least 1 of the 1 critical gene targets is altered. EGI: altered gene function or expression causes enhanced genetic instability. NEOM TABLE: Neoplastic transformation as a function of dose and dose rate at t=42.000 days. Parameters: TFS=1.1500E-05 (1/wk), TFU=2.0000E-03 (1/wk), NCM=1, NCG=1, and NCG*PGH*PGA=4.3E-06. ====================================================================================================== Dose Dose Rate Non-Lethal Genetic Instability *** TRANSFORMATION FREQUENCY *** SIM ID (Gy) (Gy/h) Mutations EGI EGI/SF BKG TPS TPI ------------------------------------------------------------------------------------------------------ 1 0.000E+00 0.000E+00 0.000E+00 0.000E+00 0.000E+00 6.8995E-05 6.8995E-05 6.8995E-05 2 1.000E-01 6.000E-01 8.594E-01 3.594E-06 3.653E-06 6.8995E-05 6.9039E-05 6.7929E-05 3 2.500E-01 6.000E-01 2.150E+00 8.768E-06 9.136E-06 6.8995E-05 6.9104E-05 6.6323E-05 4 5.000E-01 6.000E-01 4.301E+00 1.682E-05 1.828E-05 6.8994E-05 6.9212E-05 6.3685E-05 5 1.000E+00 6.000E-01 8.605E+00 3.091E-05 3.657E-05 6.8993E-05 6.9429E-05 5.8681E-05 6 1.500E+00 6.000E-01 1.291E+01 4.259E-05 5.486E-05 6.8991E-05 6.9646E-05 5.4063E-05 7 2.000E+00 6.000E-01 1.721E+01 5.215E-05 7.315E-05 6.8990E-05 6.9863E-05 4.9808E-05 8 3.000E+00 6.000E-01 2.582E+01 6.599E-05 1.097E-04 6.8988E-05 7.0297E-05 4.2274E-05 9 4.000E+00 6.000E-01 3.443E+01 7.422E-05 1.463E-04 6.8985E-05 7.0730E-05 3.5879E-05 10 5.000E+00 6.000E-01 4.304E+01 7.825E-05 1.829E-04 6.8983E-05 7.1164E-05 3.0449E-05 11 6.000E+00 6.000E-01 5.164E+01 7.921E-05 2.195E-04 6.8980E-05 7.1598E-05 2.5841E-05 12 7.000E+00 6.000E-01 6.025E+01 7.795E-05 2.560E-04 6.8978E-05 7.2032E-05 2.1929E-05 13 8.000E+00 6.000E-01 6.886E+01 7.514E-05 2.926E-04 6.8975E-05 7.2465E-05 1.8609E-05 14 9.000E+00 6.000E-01 7.747E+01 7.130E-05 3.292E-04 6.8973E-05 7.2899E-05 1.5790E-05 15 1.000E+01 6.000E-01 8.608E+01 6.683E-05 3.658E-04 6.8970E-05 7.3333E-05 1.3399E-05 16 1.250E+01 6.000E-01 1.076E+02 5.458E-05 4.572E-04 6.8964E-05 7.4417E-05 8.8849E-06 17 1.500E+01 6.000E-01 1.291E+02 4.280E-05 5.486E-04 6.8957E-05 7.5501E-05 5.8905E-06 18 1.750E+01 6.000E-01 1.506E+02 3.263E-05 6.400E-04 6.8951E-05 7.6585E-05 3.9045E-06 19 2.000E+01 6.000E-01 1.722E+02 2.437E-05 7.314E-04 6.8945E-05 7.7669E-05 2.5876E-06 20 2.500E+01 6.000E-01 2.152E+02 1.300E-05 9.142E-04 6.8932E-05 7.9837E-05 1.1358E-06 21 3.000E+01 6.000E-01 2.582E+02 6.663E-06 1.097E-03 6.8920E-05 8.2004E-05 4.9815E-07 22 3.500E+01 6.000E-01 3.013E+02 3.319E-06 1.280E-03 6.8907E-05 8.4170E-05 2.1834E-07 23 0.000E+00 0.000E+00 0.000E+00 0.000E+00 0.000E+00 6.8995E-05 6.8995E-05 6.8995E-05 24 1.000E-01 1.200E+00 8.595E-01 3.594E-06 3.653E-06 6.8995E-05 6.9039E-05 6.7928E-05 25 2.500E-01 1.200E+00 2.150E+00 8.767E-06 9.137E-06 6.8995E-05 6.9104E-05 6.6307E-05 26 5.000E-01 1.200E+00 4.303E+00 1.681E-05 1.829E-05 6.8994E-05 6.9212E-05 6.3605E-05 27 1.000E+00 1.200E+00 8.613E+00 3.078E-05 3.661E-05 6.8993E-05 6.9429E-05 5.8384E-05 28 1.500E+00 1.200E+00 1.293E+01 4.222E-05 5.493E-05 6.8991E-05 6.9647E-05 5.3530E-05 29 2.000E+00 1.200E+00 1.724E+01 5.145E-05 7.326E-05 6.8990E-05 6.9864E-05 4.9064E-05 30 3.000E+00 1.200E+00 2.586E+01 6.443E-05 1.099E-04 6.8988E-05 7.0299E-05 4.1209E-05 31 4.000E+00 1.200E+00 3.449E+01 7.171E-05 1.466E-04 6.8985E-05 7.0733E-05 3.4610E-05 32 5.000E+00 1.200E+00 4.311E+01 7.483E-05 1.832E-04 6.8983E-05 7.1168E-05 2.9066E-05 33 6.000E+00 1.200E+00 5.174E+01 7.495E-05 2.199E-04 6.8980E-05 7.1603E-05 2.4409E-05 34 7.000E+00 1.200E+00 6.036E+01 7.299E-05 2.565E-04 6.8978E-05 7.2037E-05 2.0497E-05 35 8.000E+00 1.200E+00 6.899E+01 6.963E-05 2.932E-04 6.8975E-05 7.2472E-05 1.7212E-05 36 9.000E+00 1.200E+00 7.762E+01 6.538E-05 3.298E-04 6.8972E-05 7.2907E-05 1.4453E-05 37 1.000E+01 1.200E+00 8.624E+01 6.064E-05 3.665E-04 6.8970E-05 7.3341E-05 1.2135E-05 38 1.250E+01 1.200E+00 1.078E+02 4.824E-05 4.581E-04 6.8964E-05 7.4428E-05 7.8388E-06 39 1.500E+01 1.200E+00 1.294E+02 3.685E-05 5.497E-04 6.8957E-05 7.5514E-05 5.0623E-06 40 1.750E+01 1.200E+00 1.509E+02 2.736E-05 6.413E-04 6.8951E-05 7.6600E-05 3.2686E-06 41 2.000E+01 1.200E+00 1.725E+02 1.990E-05 7.328E-04 6.8945E-05 7.7686E-05 2.1100E-06 42 2.500E+01 1.200E+00 2.156E+02 1.008E-05 9.160E-04 6.8932E-05 7.9858E-05 8.7876E-07 43 3.000E+01 1.200E+00 2.587E+02 4.900E-06 1.099E-03 6.8919E-05 8.2030E-05 3.6571E-07 44 3.500E+01 1.200E+00 3.019E+02 2.316E-06 1.282E-03 6.8907E-05 8.4201E-05 1.5209E-07 45 0.000E+00 0.000E+00 0.000E+00 0.000E+00 0.000E+00 6.8995E-05 6.8995E-05 6.8995E-05 46 1.000E-01 3.000E+00 8.595E-01 3.594E-06 3.653E-06 6.8995E-05 6.9039E-05 6.7927E-05 47 2.500E-01 3.000E+00 2.150E+00 8.767E-06 9.139E-06 6.8995E-05 6.9104E-05 6.6295E-05 48 5.000E-01 3.000E+00 4.305E+00 1.679E-05 1.830E-05 6.8994E-05 6.9212E-05 6.3530E-05 49 1.000E+00 3.000E+00 8.624E+00 3.062E-05 3.665E-05 6.8993E-05 6.9430E-05 5.8011E-05 50 1.500E+00 3.000E+00 1.295E+01 4.166E-05 5.504E-05 6.8991E-05 6.9648E-05 5.2713E-05 51 2.000E+00 3.000E+00 1.728E+01 5.021E-05 7.345E-05 6.8990E-05 6.9866E-05 4.7760E-05 52 3.000E+00 3.000E+00 2.595E+01 6.124E-05 1.103E-04 6.8988E-05 7.0303E-05 3.9034E-05 53 4.000E+00 3.000E+00 3.463E+01 6.620E-05 1.472E-04 6.8985E-05 7.0740E-05 3.1822E-05 54 5.000E+00 3.000E+00 4.330E+01 6.701E-05 1.840E-04 6.8983E-05 7.1178E-05 2.5919E-05 55 6.000E+00 3.000E+00 5.198E+01 6.509E-05 2.209E-04 6.8980E-05 7.1615E-05 2.1103E-05 56 7.000E+00 3.000E+00 6.066E+01 6.146E-05 2.578E-04 6.8977E-05 7.2052E-05 1.7180E-05 57 8.000E+00 3.000E+00 6.934E+01 5.684E-05 2.946E-04 6.8975E-05 7.2489E-05 1.3986E-05 58 9.000E+00 3.000E+00 7.801E+01 5.175E-05 3.315E-04 6.8972E-05 7.2927E-05 1.1384E-05 59 1.000E+01 3.000E+00 8.669E+01 4.653E-05 3.684E-04 6.8970E-05 7.3364E-05 9.2666E-06 60 1.250E+01 3.000E+00 1.084E+02 3.425E-05 4.605E-04 6.8963E-05 7.4457E-05 5.5383E-06 61 1.500E+01 3.000E+00 1.301E+02 2.421E-05 5.527E-04 6.8957E-05 7.5549E-05 3.3093E-06 62 1.750E+01 3.000E+00 1.518E+02 1.663E-05 6.448E-04 6.8951E-05 7.6642E-05 1.9770E-06 63 2.000E+01 3.000E+00 1.735E+02 1.119E-05 7.369E-04 6.8944E-05 7.7735E-05 1.1808E-06 64 2.500E+01 3.000E+00 2.168E+02 4.853E-06 9.212E-04 6.8932E-05 7.9920E-05 4.2101E-07 65 3.000E+01 3.000E+00 2.602E+02 2.019E-06 1.105E-03 6.8919E-05 8.2104E-05 1.4999E-07 66 3.500E+01 3.000E+00 3.036E+02 8.170E-07 1.290E-03 6.8906E-05 8.4288E-05 5.3400E-08 67 0.000E+00 0.000E+00 0.000E+00 0.000E+00 0.000E+00 6.8995E-05 6.8995E-05 6.8995E-05 68 1.000E-01 6.000E+00 8.595E-01 3.594E-06 3.653E-06 6.8995E-05 6.9039E-05 6.7927E-05 69 2.500E-01 6.000E+00 2.150E+00 8.767E-06 9.139E-06 6.8995E-05 6.9104E-05 6.6290E-05 70 5.000E-01 6.000E+00 4.306E+00 1.679E-05 1.830E-05 6.8994E-05 6.9212E-05 6.3499E-05 71 1.000E+00 6.000E+00 8.629E+00 3.054E-05 3.667E-05 6.8993E-05 6.9430E-05 5.7820E-05 72 1.500E+00 6.000E+00 1.297E+01 4.132E-05 5.511E-05 6.8991E-05 6.9649E-05 5.2223E-05 73 2.000E+00 6.000E+00 1.731E+01 4.937E-05 7.358E-05 6.8990E-05 6.9868E-05 4.6876E-05 74 3.000E+00 6.000E+00 2.603E+01 5.865E-05 1.106E-04 6.8988E-05 7.0307E-05 3.7277E-05 75 4.000E+00 6.000E+00 3.477E+01 6.121E-05 1.477E-04 6.8985E-05 7.0747E-05 2.9312E-05 76 5.000E+00 6.000E+00 4.351E+01 5.947E-05 1.849E-04 6.8982E-05 7.1188E-05 2.2898E-05 77 6.000E+00 6.000E+00 5.226E+01 5.525E-05 2.221E-04 6.8980E-05 7.1629E-05 1.7819E-05 78 7.000E+00 6.000E+00 6.102E+01 4.978E-05 2.593E-04 6.8977E-05 7.2070E-05 1.3835E-05 79 8.000E+00 6.000E+00 6.978E+01 4.387E-05 2.965E-04 6.8975E-05 7.2512E-05 1.0728E-05 80 9.000E+00 6.000E+00 7.854E+01 3.802E-05 3.337E-04 6.8972E-05 7.2953E-05 8.3117E-06 81 1.000E+01 6.000E+00 8.730E+01 3.253E-05 3.709E-04 6.8970E-05 7.3394E-05 6.4368E-06 82 1.250E+01 6.000E+00 1.092E+02 2.114E-05 4.640E-04 6.8963E-05 7.4498E-05 3.3936E-06 83 1.500E+01 6.000E+00 1.311E+02 1.317E-05 5.570E-04 6.8957E-05 7.5601E-05 1.7880E-06 84 1.750E+01 6.000E+00 1.530E+02 7.981E-06 6.500E-04 6.8950E-05 7.6704E-05 9.4170E-07 85 2.000E+01 6.000E+00 1.749E+02 4.735E-06 7.431E-04 6.8944E-05 7.7807E-05 4.9586E-07 86 2.500E+01 6.000E+00 2.187E+02 1.595E-06 9.291E-04 6.8931E-05 8.0013E-05 1.3740E-07 87 3.000E+01 6.000E+00 2.625E+02 5.159E-07 1.115E-03 6.8918E-05 8.2219E-05 3.8043E-08 88 3.500E+01 6.000E+00 3.063E+02 1.622E-07 1.301E-03 6.8905E-05 8.4424E-05 1.0526E-08 89 0.000E+00 0.000E+00 0.000E+00 0.000E+00 0.000E+00 6.8995E-05 6.8995E-05 6.8995E-05 90 1.000E-01 1.200E+01 8.595E-01 3.594E-06 3.653E-06 6.8995E-05 6.9039E-05 6.7927E-05 91 2.500E-01 1.200E+01 2.150E+00 8.767E-06 9.139E-06 6.8995E-05 6.9104E-05 6.6288E-05 92 5.000E-01 1.200E+01 4.306E+00 1.679E-05 1.830E-05 6.8994E-05 6.9212E-05 6.3481E-05 93 1.000E+00 1.200E+01 8.633E+00 3.049E-05 3.669E-05 6.8993E-05 6.9430E-05 5.7706E-05 94 1.500E+00 1.200E+01 1.298E+01 4.110E-05 5.515E-05 6.8991E-05 6.9649E-05 5.1907E-05 95 2.000E+00 1.200E+01 1.734E+01 4.879E-05 7.367E-05 6.8990E-05 6.9869E-05 4.6266E-05 96 3.000E+00 1.200E+01 2.609E+01 5.666E-05 1.109E-04 6.8988E-05 7.0310E-05 3.5928E-05 97 4.000E+00 1.200E+01 3.489E+01 5.706E-05 1.483E-04 6.8985E-05 7.0754E-05 2.7233E-05 98 5.000E+00 1.200E+01 4.371E+01 5.288E-05 1.858E-04 6.8982E-05 7.1198E-05 2.0268E-05 99 6.000E+00 1.200E+01 5.256E+01 4.638E-05 2.234E-04 6.8980E-05 7.1644E-05 1.4876E-05 100 7.000E+00 1.200E+01 6.143E+01 3.913E-05 2.610E-04 6.8977E-05 7.2091E-05 1.0806E-05 101 8.000E+00 1.200E+01 7.031E+01 3.207E-05 2.988E-04 6.8975E-05 7.2538E-05 7.7866E-06 102 9.000E+00 1.200E+01 7.920E+01 2.572E-05 3.365E-04 6.8972E-05 7.2986E-05 5.5774E-06 103 1.000E+01 1.200E+01 8.810E+01 2.027E-05 3.743E-04 6.8969E-05 7.3435E-05 3.9769E-06 104 1.250E+01 1.200E+01 1.104E+02 1.060E-05 4.689E-04 6.8963E-05 7.4556E-05 1.6847E-06 105 1.500E+01 1.200E+01 1.326E+02 5.255E-06 5.636E-04 6.8956E-05 7.5679E-05 7.0569E-07 106 1.750E+01 1.200E+01 1.549E+02 2.519E-06 6.583E-04 6.8950E-05 7.6802E-05 2.9392E-07 107 2.000E+01 1.200E+01 1.772E+02 1.179E-06 7.530E-04 6.8943E-05 7.7925E-05 1.2206E-07 108 2.500E+01 1.200E+01 2.218E+02 2.465E-07 9.424E-04 6.8930E-05 8.0171E-05 2.0967E-08 109 3.000E+01 1.200E+01 2.664E+02 4.934E-08 1.132E-03 6.8917E-05 8.2417E-05 3.5932E-09 110 3.500E+01 1.200E+01 3.110E+02 9.598E-09 1.321E-03 6.8904E-05 8.4662E-05 6.1511E-10 111 0.000E+00 0.000E+00 0.000E+00 0.000E+00 0.000E+00 6.8995E-05 6.8995E-05 6.8995E-05 112 1.000E-01 3.000E+01 8.595E-01 3.594E-06 3.653E-06 6.8995E-05 6.9039E-05 6.7927E-05 113 2.500E-01 3.000E+01 2.150E+00 8.767E-06 9.139E-06 6.8995E-05 6.9104E-05 6.6287E-05 114 5.000E-01 3.000E+01 4.307E+00 1.678E-05 1.830E-05 6.8994E-05 6.9212E-05 6.3470E-05 115 1.000E+00 3.000E+01 8.635E+00 3.046E-05 3.670E-05 6.8993E-05 6.9430E-05 5.7630E-05 116 1.500E+00 3.000E+01 1.298E+01 4.095E-05 5.518E-05 6.8991E-05 6.9650E-05 5.1689E-05 117 2.000E+00 3.000E+01 1.735E+01 4.837E-05 7.374E-05 6.8990E-05 6.9870E-05 4.5827E-05 118 3.000E+00 3.000E+01 2.614E+01 5.512E-05 1.111E-04 6.8988E-05 7.0313E-05 3.4890E-05 119 4.000E+00 3.000E+01 3.499E+01 5.372E-05 1.487E-04 6.8985E-05 7.0759E-05 2.5559E-05 120 5.000E+00 3.000E+01 4.390E+01 4.742E-05 1.866E-04 6.8982E-05 7.1208E-05 1.8097E-05 121 6.000E+00 3.000E+01 5.286E+01 3.898E-05 2.246E-04 6.8980E-05 7.1659E-05 1.2433E-05 122 7.000E+00 3.000E+01 6.187E+01 3.032E-05 2.629E-04 6.8977E-05 7.2113E-05 8.3166E-06 123 8.000E+00 3.000E+01 7.091E+01 2.256E-05 3.013E-04 6.8974E-05 7.2569E-05 5.4332E-06 124 9.000E+00 3.000E+01 7.999E+01 1.618E-05 3.399E-04 6.8972E-05 7.3026E-05 3.4760E-06 125 1.000E+01 3.000E+01 8.910E+01 1.125E-05 3.786E-04 6.8969E-05 7.3485E-05 2.1831E-06 126 1.250E+01 3.000E+01 1.120E+02 4.065E-06 4.758E-04 6.8962E-05 7.4638E-05 6.3773E-07 127 1.500E+01 3.000E+01 1.350E+02 1.306E-06 5.736E-04 6.8956E-05 7.5797E-05 1.7264E-07 128 1.750E+01 3.000E+01 1.581E+02 3.856E-07 6.717E-04 6.8949E-05 7.6961E-05 4.4181E-08 129 2.000E+01 3.000E+01 1.813E+02 1.069E-07 7.701E-04 6.8942E-05 7.8128E-05 1.0847E-08 130 2.500E+01 3.000E+01 2.277E+02 7.226E-09 9.675E-04 6.8928E-05 8.0469E-05 6.0105E-10 131 3.000E+01 3.000E+01 2.743E+02 4.375E-10 1.165E-03 6.8915E-05 8.2815E-05 3.1093E-11 132 3.500E+01 3.000E+01 3.210E+02 2.479E-11 1.363E-03 6.8901E-05 8.5163E-05 1.5488E-12 133 0.000E+00 0.000E+00 0.000E+00 0.000E+00 0.000E+00 6.8995E-05 6.8995E-05 6.8995E-05 134 1.000E-01 7.680E+01 8.595E-01 3.594E-06 3.653E-06 6.8995E-05 6.9039E-05 6.7927E-05 135 2.500E-01 7.680E+01 2.150E+00 8.767E-06 9.139E-06 6.8995E-05 6.9104E-05 6.6286E-05 136 5.000E-01 7.680E+01 4.307E+00 1.678E-05 1.830E-05 6.8994E-05 6.9212E-05 6.3466E-05 137 1.000E+00 7.680E+01 8.636E+00 3.045E-05 3.670E-05 6.8993E-05 6.9430E-05 5.7598E-05 138 1.500E+00 7.680E+01 1.299E+01 4.088E-05 5.519E-05 6.8991E-05 6.9650E-05 5.1593E-05 139 2.000E+00 7.680E+01 1.736E+01 4.818E-05 7.377E-05 6.8990E-05 6.9870E-05 4.5630E-05 140 3.000E+00 7.680E+01 2.616E+01 5.441E-05 1.112E-04 6.8988E-05 7.0314E-05 3.4407E-05 141 4.000E+00 7.680E+01 3.505E+01 5.212E-05 1.489E-04 6.8985E-05 7.0761E-05 2.4764E-05 142 5.000E+00 7.680E+01 4.400E+01 4.479E-05 1.870E-04 6.8982E-05 7.1213E-05 1.7058E-05 143 6.000E+00 7.680E+01 5.303E+01 3.545E-05 2.253E-04 6.8980E-05 7.1668E-05 1.1273E-05 144 7.000E+00 7.680E+01 6.212E+01 2.622E-05 2.640E-04 6.8977E-05 7.2126E-05 7.1645E-06 145 8.000E+00 7.680E+01 7.127E+01 1.831E-05 3.028E-04 6.8974E-05 7.2587E-05 4.3885E-06 146 9.000E+00 7.680E+01 8.048E+01 1.215E-05 3.420E-04 6.8972E-05 7.3051E-05 2.5962E-06 147 1.000E+01 7.680E+01 8.974E+01 7.709E-06 3.813E-04 6.8969E-05 7.3517E-05 1.4862E-06 148 1.250E+01 7.680E+01 1.131E+02 2.079E-06 4.806E-04 6.8962E-05 7.4695E-05 3.2303E-07 149 1.500E+01 7.680E+01 1.368E+02 4.545E-07 5.811E-04 6.8955E-05 7.5887E-05 5.9354E-08 150 1.750E+01 7.680E+01 1.607E+02 8.350E-08 6.826E-04 6.8948E-05 7.7091E-05 9.4293E-09 151 2.000E+01 7.680E+01 1.848E+02 1.324E-08 7.850E-04 6.8941E-05 7.8305E-05 1.3206E-09 152 2.500E+01 7.680E+01 2.335E+02 2.326E-10 9.920E-04 6.8927E-05 8.0759E-05 1.8933E-11 153 3.000E+01 7.680E+01 2.828E+02 2.814E-12 1.201E-03 6.8912E-05 8.3240E-05 1.9503E-13 154 3.500E+01 7.680E+01 3.325E+02 2.579E-14 1.412E-03 6.8898E-05 8.5742E-05 1.5661E-15 ------------------------------------------------------------------------------------------------------ TPS: Transformation frequency per survivor, TPI: Transformation frequency per irradiated cell EGI: Probabilty random mutational events caused enhanced genetic instability (EGI). BKG: Background (spontaneous) cell transformation frequency TLKM TABLE: LQ model dose protraction factor(s) and cell survival estimates (FRDL=100.0%). LQ model parameters are: alpha = 0.1596 (1/Gy), alpha/beta = 5.7453 (Gy), lamda1 = 3.154E+00 (1/h), lamda2 = 3.076E+00 (1/h). ================================================================================================================= --- Duration (h) --- Dose Dose Rate* *********** G FACTOR *********** ******* SF(dose) ******* SIM ID Exposure Sim (Gy) (Gy/h) GL1 GL2 GEFF SF1 SF2 ----------------------------------------------------------------------------------------------------------------- 1 2.778E-13 9.600E+01 0.000E+00 0.000E+00 0.000E+00 0.000E+00 0.000E+00 1.0000E+00 1.000000E+00 2 1.667E-01 2.417E+01 1.000E-01 6.000E-01 8.456E-01 8.489E-01 8.458E-01 9.8394E-01 9.839352E-01 3 4.167E-01 2.442E+01 2.500E-01 6.000E-01 6.750E-01 6.809E-01 6.753E-01 9.5976E-01 9.597589E-01 4 8.333E-01 2.483E+01 5.000E-01 6.000E-01 4.923E-01 4.993E-01 4.927E-01 9.2014E-01 9.201457E-01 5 1.667E+00 2.567E+01 1.000E+00 6.000E-01 3.085E-01 3.145E-01 3.088E-01 8.4518E-01 8.452005E-01 6 2.500E+00 2.650E+01 1.500E+00 6.000E-01 2.215E-01 2.263E-01 2.218E-01 7.7623E-01 7.762618E-01 7 3.333E+00 2.733E+01 2.000E+00 6.000E-01 1.721E-01 1.760E-01 1.724E-01 7.1290E-01 7.129395E-01 8 5.000E+00 2.900E+01 3.000E+00 6.000E-01 1.188E-01 1.216E-01 1.189E-01 6.0131E-01 6.013691E-01 9 6.667E+00 3.067E+01 4.000E+00 6.000E-01 9.059E-02 9.277E-02 9.072E-02 5.0719E-01 5.072586E-01 10 8.333E+00 3.233E+01 5.000E+00 6.000E-01 7.320E-02 7.498E-02 7.331E-02 4.2780E-01 4.278759E-01 11 1.000E+01 3.400E+01 6.000E+00 6.000E-01 6.140E-02 6.291E-02 6.149E-02 3.6084E-01 3.609161E-01 12 1.167E+01 3.567E+01 7.000E+00 6.000E-01 5.287E-02 5.418E-02 5.295E-02 3.0436E-01 3.044350E-01 13 1.333E+01 3.733E+01 8.000E+00 6.000E-01 4.643E-02 4.758E-02 4.650E-02 2.5672E-01 2.567929E-01 14 1.500E+01 3.900E+01 9.000E+00 6.000E-01 4.138E-02 4.241E-02 4.144E-02 2.1654E-01 2.166064E-01 15 1.667E+01 4.067E+01 1.000E+01 6.000E-01 3.732E-02 3.825E-02 3.738E-02 1.8264E-01 1.827089E-01 16 2.083E+01 4.483E+01 1.250E+01 6.000E-01 2.997E-02 3.072E-02 3.002E-02 1.1934E-01 1.193935E-01 17 2.500E+01 4.900E+01 1.500E+01 6.000E-01 2.504E-02 2.567E-02 2.508E-02 7.7977E-02 7.801921E-02 18 2.917E+01 5.317E+01 1.750E+01 6.000E-01 2.150E-02 2.204E-02 2.154E-02 5.0950E-02 5.098266E-02 19 3.333E+01 5.733E+01 2.000E+01 6.000E-01 1.884E-02 1.932E-02 1.887E-02 3.3291E-02 3.331528E-02 20 4.167E+01 6.567E+01 2.500E+01 6.000E-01 1.510E-02 1.548E-02 1.513E-02 1.4213E-02 1.422608E-02 21 5.000E+01 7.400E+01 3.000E+01 6.000E-01 1.260E-02 1.292E-02 1.262E-02 6.0681E-03 6.074732E-03 22 5.833E+01 8.233E+01 3.500E+01 6.000E-01 1.081E-02 1.108E-02 1.083E-02 2.5907E-03 2.593994E-03 23 2.778E-13 9.600E+01 0.000E+00 0.000E+00 0.000E+00 0.000E+00 0.000E+00 1.0000E+00 1.000000E+00 24 8.333E-02 2.408E+01 1.000E-01 1.200E+00 9.179E-01 9.198E-01 9.177E-01 9.8392E-01 9.839156E-01 25 2.083E-01 2.421E+01 2.500E-01 1.200E+00 8.127E-01 8.167E-01 8.124E-01 9.5953E-01 9.595306E-01 26 4.167E-01 2.442E+01 5.000E-01 1.200E+00 6.750E-01 6.809E-01 6.745E-01 9.1897E-01 9.189849E-01 27 8.333E-01 2.483E+01 1.000E+00 1.200E+00 4.923E-01 4.993E-01 4.918E-01 8.4087E-01 8.409158E-01 28 1.250E+00 2.525E+01 1.500E+00 1.200E+00 3.811E-01 3.878E-01 3.806E-01 7.6851E-01 7.685941E-01 29 1.667E+00 2.567E+01 2.000E+00 1.200E+00 3.085E-01 3.145E-01 3.080E-01 7.0215E-01 7.022757E-01 30 2.500E+00 2.650E+01 3.000E+00 1.200E+00 2.215E-01 2.263E-01 2.211E-01 5.8601E-01 5.862020E-01 31 3.333E+00 2.733E+01 4.000E+00 1.200E+00 1.721E-01 1.760E-01 1.718E-01 4.8906E-01 4.892957E-01 32 4.167E+00 2.817E+01 5.000E+00 1.200E+00 1.406E-01 1.439E-01 1.404E-01 4.0815E-01 4.084082E-01 33 5.000E+00 2.900E+01 6.000E+00 1.200E+00 1.188E-01 1.216E-01 1.186E-01 3.4063E-01 3.408925E-01 34 5.833E+00 2.983E+01 7.000E+00 1.200E+00 1.028E-01 1.053E-01 1.026E-01 2.8428E-01 2.845381E-01 35 6.667E+00 3.067E+01 8.000E+00 1.200E+00 9.059E-02 9.277E-02 9.043E-02 2.3725E-01 2.374998E-01 36 7.500E+00 3.150E+01 9.000E+00 1.200E+00 8.097E-02 8.294E-02 8.082E-02 1.9800E-01 1.982377E-01 37 8.333E+00 3.233E+01 1.000E+01 1.200E+00 7.320E-02 7.498E-02 7.306E-02 1.6524E-01 1.654662E-01 38 1.042E+01 3.442E+01 1.250E+01 1.200E+00 5.902E-02 6.047E-02 5.891E-02 1.0514E-01 1.053214E-01 39 1.250E+01 3.650E+01 1.500E+01 1.200E+00 4.944E-02 5.066E-02 4.935E-02 6.6898E-02 6.703846E-02 40 1.458E+01 3.858E+01 1.750E+01 1.200E+00 4.253E-02 4.359E-02 4.246E-02 4.2566E-02 4.267086E-02 41 1.667E+01 4.067E+01 2.000E+01 1.200E+00 3.732E-02 3.825E-02 3.725E-02 2.7084E-02 2.716056E-02 42 2.083E+01 4.483E+01 2.500E+01 1.200E+00 2.997E-02 3.072E-02 2.992E-02 1.0965E-02 1.100408E-02 43 2.500E+01 4.900E+01 3.000E+01 1.200E+00 2.504E-02 2.567E-02 2.499E-02 4.4392E-03 4.458290E-03 44 2.917E+01 5.317E+01 3.500E+01 1.200E+00 2.150E-02 2.204E-02 2.146E-02 1.7972E-03 1.806272E-03 45 2.778E-13 9.600E+01 0.000E+00 0.000E+00 0.000E+00 0.000E+00 0.000E+00 1.0000E+00 1.000000E+00 46 3.333E-02 2.403E+01 1.000E-01 3.000E+00 9.659E-01 9.667E-01 9.654E-01 9.8390E-01 9.839025E-01 47 8.333E-02 2.408E+01 2.500E-01 3.000E+00 9.179E-01 9.198E-01 9.169E-01 9.5935E-01 9.593565E-01 48 1.667E-01 2.417E+01 5.000E-01 3.000E+00 8.456E-01 8.489E-01 8.439E-01 9.1789E-01 9.179044E-01 49 3.333E-01 2.433E+01 1.000E+00 3.000E+00 7.252E-01 7.305E-01 7.226E-01 8.3546E-01 8.355407E-01 50 5.000E-01 2.450E+01 1.500E+00 3.000E+00 6.302E-01 6.365E-01 6.270E-01 7.5664E-01 7.568456E-01 51 6.667E-01 2.467E+01 2.000E+00 3.000E+00 5.540E-01 5.609E-01 5.507E-01 6.8323E-01 6.835899E-01 52 1.000E+00 2.500E+01 3.000E+00 3.000E+00 4.416E-01 4.486E-01 4.383E-01 5.5457E-01 5.552267E-01 53 1.333E+00 2.533E+01 4.000E+00 3.000E+00 3.642E-01 3.707E-01 3.610E-01 4.4895E-01 4.498389E-01 54 1.667E+00 2.567E+01 5.000E+00 3.000E+00 3.085E-01 3.145E-01 3.056E-01 3.6310E-01 3.641399E-01 55 2.000E+00 2.600E+01 6.000E+00 3.000E+00 2.669E-01 2.724E-01 2.642E-01 2.9358E-01 2.946795E-01 56 2.333E+00 2.633E+01 7.000E+00 3.000E+00 2.348E-01 2.399E-01 2.324E-01 2.3734E-01 2.384442E-01 57 2.667E+00 2.667E+01 8.000E+00 3.000E+00 2.095E-01 2.141E-01 2.073E-01 1.9187E-01 1.929337E-01 58 3.000E+00 2.700E+01 9.000E+00 3.000E+00 1.890E-01 1.933E-01 1.870E-01 1.5510E-01 1.561077E-01 59 3.333E+00 2.733E+01 1.000E+01 3.000E+00 1.721E-01 1.760E-01 1.703E-01 1.2539E-01 1.263102E-01 60 4.167E+00 2.817E+01 1.250E+01 3.000E+00 1.406E-01 1.439E-01 1.390E-01 7.3671E-02 7.438275E-02 61 5.000E+00 2.900E+01 1.500E+01 3.000E+00 1.188E-01 1.216E-01 1.174E-01 4.3286E-02 4.380317E-02 62 5.833E+00 2.983E+01 1.750E+01 3.000E+00 1.028E-01 1.053E-01 1.016E-01 2.5433E-02 2.579519E-02 63 6.667E+00 3.067E+01 2.000E+01 3.000E+00 9.059E-02 9.277E-02 8.955E-02 1.4943E-02 1.519050E-02 64 8.333E+00 3.233E+01 2.500E+01 3.000E+00 7.320E-02 7.498E-02 7.234E-02 5.1587E-03 5.267910E-03 65 1.000E+01 3.400E+01 3.000E+01 3.000E+00 6.140E-02 6.291E-02 6.068E-02 1.7809E-03 1.826858E-03 66 1.167E+01 3.567E+01 3.500E+01 3.000E+00 5.287E-02 5.418E-02 5.225E-02 6.1480E-04 6.335360E-04 67 2.778E-13 9.600E+01 0.000E+00 0.000E+00 0.000E+00 0.000E+00 0.000E+00 1.0000E+00 1.000000E+00 68 1.667E-02 2.402E+01 1.000E-01 6.000E+00 9.827E-01 9.831E-01 9.822E-01 9.8390E-01 9.838980E-01 69 4.167E-02 2.404E+01 2.500E-01 6.000E+00 9.576E-01 9.586E-01 9.564E-01 9.5929E-01 9.592907E-01 70 8.333E-02 2.408E+01 5.000E-01 6.000E+00 9.179E-01 9.198E-01 9.156E-01 9.1743E-01 9.174476E-01 71 1.667E-01 2.417E+01 1.000E+00 6.000E+00 8.456E-01 8.489E-01 8.416E-01 8.3268E-01 8.327841E-01 72 2.500E-01 2.425E+01 1.500E+00 6.000E+00 7.818E-01 7.862E-01 7.765E-01 7.4952E-01 7.498100E-01 73 3.333E-01 2.433E+01 2.000E+00 6.000E+00 7.252E-01 7.305E-01 7.190E-01 6.7038E-01 6.709267E-01 74 5.000E-01 2.450E+01 3.000E+00 6.000E+00 6.302E-01 6.365E-01 6.227E-01 5.2905E-01 5.302023E-01 75 6.667E-01 2.467E+01 4.000E+00 6.000E+00 5.540E-01 5.609E-01 5.461E-01 4.1260E-01 4.143165E-01 76 8.333E-01 2.483E+01 5.000E+00 6.000E+00 4.923E-01 4.993E-01 4.842E-01 3.1954E-01 3.216505E-01 77 1.000E+00 2.500E+01 6.000E+00 6.000E+00 4.416E-01 4.486E-01 4.336E-01 2.4643E-01 2.487617E-01 78 1.167E+00 2.517E+01 7.000E+00 6.000E+00 3.995E-01 4.063E-01 3.917E-01 1.8959E-01 1.919644E-01 79 1.333E+00 2.533E+01 8.000E+00 6.000E+00 3.642E-01 3.707E-01 3.567E-01 1.4564E-01 1.479441E-01 80 1.500E+00 2.550E+01 9.000E+00 6.000E+00 3.342E-01 3.405E-01 3.270E-01 1.1179E-01 1.139327E-01 81 1.667E+00 2.567E+01 1.000E+01 6.000E+00 3.085E-01 3.145E-01 3.016E-01 8.5757E-02 8.770193E-02 82 2.083E+00 2.608E+01 1.250E+01 6.000E+00 2.581E-01 2.635E-01 2.520E-01 4.4157E-02 4.555360E-02 83 2.500E+00 2.650E+01 1.500E+01 6.000E+00 2.215E-01 2.263E-01 2.160E-01 2.2723E-02 2.365012E-02 84 2.917E+00 2.692E+01 1.750E+01 6.000E+00 1.938E-01 1.981E-01 1.889E-01 1.1692E-02 1.227698E-02 85 3.333E+00 2.733E+01 2.000E+01 6.000E+00 1.721E-01 1.760E-01 1.677E-01 6.0155E-03 6.372887E-03 86 4.167E+00 2.817E+01 2.500E+01 6.000E+00 1.406E-01 1.439E-01 1.369E-01 1.5924E-03 1.717187E-03 87 5.000E+00 2.900E+01 3.000E+01 6.000E+00 1.188E-01 1.216E-01 1.156E-01 4.2151E-04 4.626977E-04 88 5.833E+00 2.983E+01 3.500E+01 6.000E+00 1.028E-01 1.053E-01 1.000E-01 1.1158E-04 1.246743E-04 89 2.778E-13 9.600E+01 0.000E+00 0.000E+00 0.000E+00 0.000E+00 0.000E+00 1.0000E+00 1.000000E+00 90 8.333E-03 2.401E+01 1.000E-01 1.200E+01 9.913E-01 9.915E-01 9.907E-01 9.8390E-01 9.838956E-01 91 2.083E-02 2.402E+01 2.500E-01 1.200E+01 9.785E-01 9.790E-01 9.771E-01 9.5925E-01 9.592562E-01 92 4.167E-02 2.404E+01 5.000E-01 1.200E+01 9.576E-01 9.586E-01 9.550E-01 9.1718E-01 9.171967E-01 93 8.333E-02 2.408E+01 1.000E+00 1.200E+01 9.179E-01 9.198E-01 9.129E-01 8.3101E-01 8.311349E-01 94 1.250E-01 2.412E+01 1.500E+00 1.200E+01 8.806E-01 8.833E-01 8.737E-01 7.4492E-01 7.452683E-01 95 1.667E-01 2.417E+01 2.000E+00 1.200E+01 8.456E-01 8.489E-01 8.369E-01 6.6150E-01 6.621890E-01 96 2.500E-01 2.425E+01 3.000E+00 1.200E+01 7.818E-01 7.862E-01 7.704E-01 5.0942E-01 5.109868E-01 97 3.333E-01 2.433E+01 4.000E+00 1.200E+01 7.252E-01 7.305E-01 7.118E-01 3.8242E-01 3.848928E-01 98 4.167E-01 2.442E+01 5.000E+00 1.200E+01 6.750E-01 6.809E-01 6.601E-01 2.8151E-01 2.846631E-01 99 5.000E-01 2.450E+01 6.000E+00 1.200E+01 6.302E-01 6.365E-01 6.143E-01 2.0411E-01 2.076437E-01 100 5.833E-01 2.458E+01 7.000E+00 1.200E+01 5.900E-01 5.967E-01 5.735E-01 1.4628E-01 1.498875E-01 101 6.667E-01 2.467E+01 8.000E+00 1.200E+01 5.540E-01 5.609E-01 5.371E-01 1.0391E-01 1.073440E-01 102 7.500E-01 2.475E+01 9.000E+00 1.200E+01 5.216E-01 5.286E-01 5.045E-01 7.3296E-02 7.641737E-02 103 8.333E-01 2.483E+01 1.000E+01 1.200E+01 4.923E-01 4.993E-01 4.751E-01 5.1430E-02 5.415540E-02 104 1.042E+00 2.504E+01 1.250E+01 1.200E+01 4.304E-01 4.373E-01 4.135E-01 2.0877E-02 2.259595E-02 105 1.250E+00 2.525E+01 1.500E+01 1.200E+01 3.811E-01 3.878E-01 3.649E-01 8.3591E-03 9.324756E-03 106 1.458E+00 2.546E+01 1.750E+01 1.200E+01 3.412E-01 3.476E-01 3.259E-01 3.3233E-03 3.827051E-03 107 1.667E+00 2.567E+01 2.000E+01 1.200E+01 3.085E-01 3.145E-01 2.940E-01 1.3163E-03 1.566414E-03 108 2.083E+00 2.608E+01 2.500E+01 1.200E+01 2.581E-01 2.635E-01 2.453E-01 2.0552E-04 2.615280E-04 109 2.500E+00 2.650E+01 3.000E+01 1.200E+01 2.215E-01 2.263E-01 2.101E-01 3.2013E-05 4.359851E-05 110 2.917E+00 2.692E+01 3.500E+01 1.200E+01 1.938E-01 1.981E-01 1.836E-01 4.9835E-06 7.265438E-06 111 2.778E-13 9.600E+01 0.000E+00 0.000E+00 0.000E+00 0.000E+00 0.000E+00 1.0000E+00 1.000000E+00 112 3.333E-03 2.400E+01 1.000E-01 3.000E+01 9.965E-01 9.966E-01 9.959E-01 9.8389E-01 9.838942E-01 113 8.333E-03 2.401E+01 2.500E-01 3.000E+01 9.913E-01 9.915E-01 9.898E-01 9.5923E-01 9.592350E-01 114 1.667E-02 2.402E+01 5.000E-01 3.000E+01 9.827E-01 9.831E-01 9.798E-01 9.1702E-01 9.170382E-01 115 3.333E-02 2.403E+01 1.000E+00 3.000E+01 9.659E-01 9.667E-01 9.603E-01 8.2991E-01 8.300420E-01 116 5.000E-02 2.405E+01 1.500E+00 3.000E+01 9.494E-01 9.506E-01 9.413E-01 7.4174E-01 7.421227E-01 117 6.667E-02 2.407E+01 2.000E+00 3.000E+01 9.334E-01 9.350E-01 9.229E-01 6.5510E-01 6.558914E-01 118 1.000E-01 2.410E+01 3.000E+00 3.000E+01 9.027E-01 9.049E-01 8.878E-01 4.9431E-01 4.962057E-01 119 1.333E-01 2.413E+01 4.000E+00 3.000E+01 8.734E-01 8.762E-01 8.546E-01 3.5813E-01 3.612178E-01 120 1.667E-01 2.417E+01 5.000E+00 3.000E+01 8.456E-01 8.489E-01 8.234E-01 2.5014E-01 2.541443E-01 121 2.000E-01 2.420E+01 6.000E+00 3.000E+01 8.191E-01 8.230E-01 7.939E-01 1.6905E-01 1.734997E-01 122 2.333E-01 2.423E+01 7.000E+00 3.000E+01 7.939E-01 7.982E-01 7.661E-01 1.1091E-01 1.153267E-01 123 2.667E-01 2.427E+01 8.000E+00 3.000E+01 7.699E-01 7.746E-01 7.397E-01 7.0842E-02 7.486974E-02 124 3.000E-01 2.430E+01 9.000E+00 3.000E+01 7.470E-01 7.520E-01 7.148E-01 4.4174E-02 4.759989E-02 125 3.333E-01 2.433E+01 1.000E+01 3.000E+01 7.252E-01 7.305E-01 6.913E-01 2.6954E-02 2.970784E-02 126 4.167E-01 2.442E+01 1.250E+01 3.000E+01 6.750E-01 6.809E-01 6.376E-01 7.2269E-03 8.544316E-03 127 5.000E-01 2.450E+01 1.500E+01 3.000E+01 6.302E-01 6.365E-01 5.904E-01 1.7630E-03 2.277668E-03 128 5.833E-01 2.458E+01 1.750E+01 3.000E+01 5.900E-01 5.967E-01 5.489E-01 3.9994E-04 5.740751E-04 129 6.667E-01 2.467E+01 2.000E+01 3.000E+01 5.540E-01 5.609E-01 5.121E-01 8.5786E-05 1.388336E-04 130 8.333E-01 2.483E+01 2.500E+01 3.000E+01 4.923E-01 4.993E-01 4.501E-01 3.5027E-06 7.469341E-06 131 1.000E+00 2.500E+01 3.000E+01 3.000E+01 4.416E-01 4.486E-01 4.003E-01 1.2890E-07 3.754473E-07 132 1.167E+00 2.517E+01 3.500E+01 3.000E+01 3.995E-01 4.063E-01 3.596E-01 4.4600E-09 1.818601E-08 133 2.778E-13 9.600E+01 0.000E+00 0.000E+00 0.000E+00 0.000E+00 0.000E+00 1.0000E+00 1.000000E+00 134 1.302E-03 2.400E+01 1.000E-01 7.680E+01 9.986E-01 9.987E-01 9.980E-01 9.8389E-01 9.838936E-01 135 3.255E-03 2.400E+01 2.500E-01 7.680E+01 9.966E-01 9.967E-01 9.951E-01 9.5922E-01 9.592262E-01 136 6.510E-03 2.401E+01 5.000E-01 7.680E+01 9.932E-01 9.934E-01 9.902E-01 9.1695E-01 9.169721E-01 137 1.302E-02 2.401E+01 1.000E+00 7.680E+01 9.864E-01 9.868E-01 9.806E-01 8.2944E-01 8.295738E-01 138 1.953E-02 2.402E+01 1.500E+00 7.680E+01 9.798E-01 9.803E-01 9.711E-01 7.4034E-01 7.407420E-01 139 2.604E-02 2.403E+01 2.000E+00 7.680E+01 9.732E-01 9.738E-01 9.618E-01 6.5223E-01 6.530660E-01 140 3.906E-02 2.404E+01 3.000E+00 7.680E+01 9.602E-01 9.611E-01 9.435E-01 4.8728E-01 4.893359E-01 141 5.208E-02 2.405E+01 4.000E+00 7.680E+01 9.474E-01 9.487E-01 9.258E-01 3.4659E-01 3.499682E-01 142 6.510E-02 2.407E+01 5.000E+00 7.680E+01 9.349E-01 9.365E-01 9.086E-01 2.3515E-01 2.395371E-01 143 7.812E-02 2.408E+01 6.000E+00 7.680E+01 9.227E-01 9.245E-01 8.919E-01 1.5248E-01 1.572978E-01 144 9.115E-02 2.409E+01 7.000E+00 7.680E+01 9.107E-01 9.127E-01 8.757E-01 9.4666E-02 9.933405E-02 145 1.042E-01 2.410E+01 8.000E+00 7.680E+01 8.989E-01 9.012E-01 8.600E-01 5.6369E-02 6.045872E-02 146 1.172E-01 2.412E+01 9.000E+00 7.680E+01 8.874E-01 8.899E-01 8.447E-01 3.2247E-02 3.553933E-02 147 1.302E-01 2.413E+01 1.000E+01 7.680E+01 8.761E-01 8.789E-01 8.298E-01 1.7751E-02 2.021624E-02 148 1.628E-01 2.416E+01 1.250E+01 7.680E+01 8.488E-01 8.521E-01 7.945E-01 3.4066E-03 4.324596E-03 149 1.953E-01 2.420E+01 1.500E+01 7.680E+01 8.227E-01 8.265E-01 7.615E-01 5.3070E-04 7.821355E-04 150 2.279E-01 2.423E+01 1.750E+01 7.680E+01 7.980E-01 8.022E-01 7.306E-01 6.8488E-05 1.223149E-04 151 2.604E-01 2.426E+01 2.000E+01 7.680E+01 7.743E-01 7.789E-01 7.018E-01 7.4567E-06 1.686452E-05 152 3.255E-01 2.433E+01 2.500E+01 7.680E+01 7.302E-01 7.355E-01 6.494E-01 5.6612E-08 2.344415E-07 153 3.906E-01 2.439E+01 3.000E+01 7.680E+01 6.901E-01 6.958E-01 6.033E-01 2.6023E-10 2.342977E-09 154 4.557E-01 2.446E+01 3.500E+01 7.680E+01 6.533E-01 6.595E-01 5.624E-01 7.9457E-13 1.826548E-11 ----------------------------------------------------------------------------------------------------------------- GL=[2*[x+exp(-x)-1]/(x*x), where x = {lamda}*{irradiation time} and GEFF=-(alpha+LOG(SF)/dose)/(beta*dose). In the formula for GEFF, SF is surviving fraction as computed using the TLK model. The effects of lethal residual damage are included in the GEFF dose protraction factor but not GL1 or GL2. The estimates of the surviving fraction are SF1 = EXP{-dose*[alpha+(gl1*beta1+gl2*beta2)*dose]} and SF2 = EXP{-dose*(alpha+geff*beta*dose)}. QECK TABLE: Tumor control probability (TCP) estimates as a function of dose and dose rate. Cell kinetic parameters are: N(0)=F0*KAP*VOL=1.00000E+00, TCC=10.0000 h, Tpot=20.000 days. The *MAX* estimate is recommended (the other TCP estimates are mainly included in the table for diagnostic purposes). ===================================================================================================================== TSIM DOSE ---- EXPECTED NUMBER OF CELLS ---- ------ TUMOR CONTROL PROBABILITY (TCP) ------- SIM ID (day) (Gy) N(0)*S(D) N(t)*S(D) NSC(t) N(0)*S(D) N(t)*S(D) NSC(t) *MAX* --------------------------------------------------------------------------------------------------------------------- 1 4.000E+00 0.000E+00 1.0000E+00 1.0000E+00 1.0000E+00 3.6788E-01 3.6788E-01 3.6788E-01 3.6788E-01 2 1.007E+00 1.000E-01 9.8394E-01 9.8394E-01 9.8394E-01 3.7384E-01 3.7384E-01 3.7384E-01 3.7384E-01 3 1.017E+00 2.500E-01 9.5976E-01 9.5976E-01 9.5976E-01 3.8299E-01 3.8299E-01 3.8299E-01 3.8299E-01 4 1.035E+00 5.000E-01 9.2015E-01 9.2015E-01 9.2015E-01 3.9846E-01 3.9846E-01 3.9846E-01 3.9846E-01 5 1.069E+00 1.000E+00 8.4520E-01 8.4520E-01 8.4520E-01 4.2947E-01 4.2947E-01 4.2947E-01 4.2947E-01 6 1.104E+00 1.500E+00 7.7626E-01 7.7626E-01 7.7626E-01 4.6012E-01 4.6012E-01 4.6012E-01 4.6012E-01 7 1.139E+00 2.000E+00 7.1294E-01 7.1294E-01 7.1294E-01 4.9020E-01 4.9020E-01 4.9020E-01 4.9020E-01 8 1.208E+00 3.000E+00 6.0137E-01 6.0137E-01 6.0137E-01 5.4806E-01 5.4806E-01 5.4806E-01 5.4806E-01 9 1.278E+00 4.000E+00 5.0726E-01 5.0726E-01 5.0726E-01 6.0214E-01 6.0214E-01 6.0214E-01 6.0214E-01 10 1.347E+00 5.000E+00 4.2788E-01 4.2788E-01 4.2788E-01 6.5189E-01 6.5189E-01 6.5189E-01 6.5189E-01 11 1.417E+00 6.000E+00 3.6092E-01 3.6092E-01 3.6092E-01 6.9704E-01 6.9704E-01 6.9704E-01 6.9704E-01 12 1.486E+00 7.000E+00 3.0443E-01 3.0443E-01 3.0443E-01 7.3754E-01 7.3754E-01 7.3754E-01 7.3754E-01 13 1.556E+00 8.000E+00 2.5679E-01 2.5679E-01 2.5679E-01 7.7353E-01 7.7353E-01 7.7353E-01 7.7353E-01 14 1.625E+00 9.000E+00 2.1661E-01 2.1661E-01 2.1661E-01 8.0525E-01 8.0525E-01 8.0525E-01 8.0525E-01 15 1.694E+00 1.000E+01 1.8271E-01 1.8271E-01 1.8271E-01 8.3301E-01 8.3301E-01 8.3301E-01 8.3301E-01 16 1.868E+00 1.250E+01 1.1939E-01 1.1939E-01 1.1939E-01 8.8746E-01 8.8746E-01 8.8746E-01 8.8746E-01 17 2.042E+00 1.500E+01 7.8019E-02 7.8019E-02 7.8019E-02 9.2495E-01 9.2495E-01 9.2495E-01 9.2495E-01 18 2.215E+00 1.750E+01 5.0983E-02 5.0983E-02 5.0983E-02 9.5030E-01 9.5030E-01 9.5030E-01 9.5030E-01 19 2.389E+00 2.000E+01 3.3315E-02 3.3315E-02 3.3315E-02 9.6723E-01 9.6723E-01 9.6723E-01 9.6723E-01 20 2.736E+00 2.500E+01 1.4226E-02 1.4226E-02 1.4226E-02 9.8587E-01 9.8587E-01 9.8587E-01 9.8587E-01 21 3.083E+00 3.000E+01 6.0747E-03 6.0747E-03 6.0747E-03 9.9394E-01 9.9394E-01 9.9394E-01 9.9394E-01 22 3.431E+00 3.500E+01 2.5940E-03 2.5940E-03 2.5940E-03 9.9741E-01 9.9741E-01 9.9741E-01 9.9741E-01 23 4.000E+00 0.000E+00 1.0000E+00 1.0000E+00 1.0000E+00 3.6788E-01 3.6788E-01 3.6788E-01 3.6788E-01 24 1.003E+00 1.000E-01 9.8392E-01 9.8392E-01 9.8392E-01 3.7384E-01 3.7384E-01 3.7384E-01 3.7384E-01 25 1.009E+00 2.500E-01 9.5953E-01 9.5953E-01 9.5953E-01 3.8307E-01 3.8307E-01 3.8307E-01 3.8307E-01 26 1.017E+00 5.000E-01 9.1898E-01 9.1898E-01 9.1898E-01 3.9892E-01 3.9892E-01 3.9892E-01 3.9892E-01 27 1.035E+00 1.000E+00 8.4092E-01 8.4092E-01 8.4092E-01 4.3132E-01 4.3132E-01 4.3132E-01 4.3132E-01 28 1.052E+00 1.500E+00 7.6859E-01 7.6859E-01 7.6859E-01 4.6366E-01 4.6366E-01 4.6366E-01 4.6366E-01 29 1.069E+00 2.000E+00 7.0228E-01 7.0228E-01 7.0228E-01 4.9546E-01 4.9546E-01 4.9546E-01 4.9546E-01 30 1.104E+00 3.000E+00 5.8620E-01 5.8620E-01 5.8620E-01 5.5644E-01 5.5644E-01 5.5644E-01 5.5644E-01 31 1.139E+00 4.000E+00 4.8930E-01 4.8930E-01 4.8930E-01 6.1306E-01 6.1306E-01 6.1306E-01 6.1306E-01 32 1.174E+00 5.000E+00 4.0841E-01 4.0841E-01 4.0841E-01 6.6471E-01 6.6471E-01 6.6471E-01 6.6471E-01 33 1.208E+00 6.000E+00 3.4089E-01 3.4089E-01 3.4089E-01 7.1114E-01 7.1114E-01 7.1114E-01 7.1114E-01 34 1.243E+00 7.000E+00 2.8454E-01 2.8454E-01 2.8454E-01 7.5236E-01 7.5236E-01 7.5236E-01 7.5236E-01 35 1.278E+00 8.000E+00 2.3750E-01 2.3750E-01 2.3750E-01 7.8860E-01 7.8860E-01 7.8860E-01 7.8860E-01 36 1.312E+00 9.000E+00 1.9824E-01 1.9824E-01 1.9824E-01 8.2017E-01 8.2017E-01 8.2017E-01 8.2017E-01 37 1.347E+00 1.000E+01 1.6547E-01 1.6547E-01 1.6547E-01 8.4750E-01 8.4750E-01 8.4750E-01 8.4750E-01 38 1.434E+00 1.250E+01 1.0532E-01 1.0532E-01 1.0532E-01 9.0004E-01 9.0004E-01 9.0004E-01 9.0004E-01 39 1.521E+00 1.500E+01 6.7038E-02 6.7038E-02 6.7038E-02 9.3516E-01 9.3516E-01 9.3516E-01 9.3516E-01 40 1.608E+00 1.750E+01 4.2671E-02 4.2671E-02 4.2671E-02 9.5823E-01 9.5823E-01 9.5823E-01 9.5823E-01 41 1.694E+00 2.000E+01 2.7161E-02 2.7161E-02 2.7161E-02 9.7320E-01 9.7320E-01 9.7320E-01 9.7320E-01 42 1.868E+00 2.500E+01 1.1004E-02 1.1004E-02 1.1004E-02 9.8906E-01 9.8906E-01 9.8906E-01 9.8906E-01 43 2.042E+00 3.000E+01 4.4583E-03 4.4583E-03 4.4583E-03 9.9555E-01 9.9555E-01 9.9555E-01 9.9555E-01 44 2.215E+00 3.500E+01 1.8063E-03 1.8063E-03 1.8063E-03 9.9820E-01 9.9820E-01 9.9820E-01 9.9820E-01 45 4.000E+00 0.000E+00 1.0000E+00 1.0000E+00 1.0000E+00 3.6788E-01 3.6788E-01 3.6788E-01 3.6788E-01 46 1.001E+00 1.000E-01 9.8390E-01 9.8390E-01 9.8390E-01 3.7385E-01 3.7385E-01 3.7385E-01 3.7385E-01 47 1.003E+00 2.500E-01 9.5936E-01 9.5936E-01 9.5936E-01 3.8314E-01 3.8314E-01 3.8314E-01 3.8314E-01 48 1.007E+00 5.000E-01 9.1790E-01 9.1790E-01 9.1790E-01 3.9936E-01 3.9936E-01 3.9936E-01 3.9936E-01 49 1.014E+00 1.000E+00 8.3554E-01 8.3554E-01 8.3554E-01 4.3364E-01 4.3364E-01 4.3364E-01 4.3364E-01 50 1.021E+00 1.500E+00 7.5685E-01 7.5685E-01 7.5685E-01 4.6914E-01 4.6914E-01 4.6914E-01 4.6914E-01 51 1.028E+00 2.000E+00 6.8359E-01 6.8359E-01 6.8359E-01 5.0480E-01 5.0480E-01 5.0480E-01 5.0480E-01 52 1.042E+00 3.000E+00 5.5523E-01 5.5523E-01 5.5523E-01 5.7394E-01 5.7394E-01 5.7394E-01 5.7394E-01 53 1.056E+00 4.000E+00 4.4984E-01 4.4984E-01 4.4984E-01 6.3773E-01 6.3773E-01 6.3773E-01 6.3773E-01 54 1.069E+00 5.000E+00 3.6414E-01 3.6414E-01 3.6414E-01 6.9479E-01 6.9479E-01 6.9479E-01 6.9479E-01 55 1.083E+00 6.000E+00 2.9468E-01 2.9468E-01 2.9468E-01 7.4477E-01 7.4477E-01 7.4477E-01 7.4477E-01 56 1.097E+00 7.000E+00 2.3844E-01 2.3844E-01 2.3844E-01 7.8785E-01 7.8785E-01 7.8785E-01 7.8785E-01 57 1.111E+00 8.000E+00 1.9293E-01 1.9293E-01 1.9293E-01 8.2454E-01 8.2454E-01 8.2454E-01 8.2454E-01 58 1.125E+00 9.000E+00 1.5611E-01 1.5611E-01 1.5611E-01 8.5547E-01 8.5547E-01 8.5547E-01 8.5547E-01 59 1.139E+00 1.000E+01 1.2631E-01 1.2631E-01 1.2631E-01 8.8134E-01 8.8134E-01 8.8134E-01 8.8134E-01 60 1.174E+00 1.250E+01 7.4383E-02 7.4383E-02 7.4383E-02 9.2832E-01 9.2832E-01 9.2832E-01 9.2832E-01 61 1.208E+00 1.500E+01 4.3803E-02 4.3803E-02 4.3803E-02 9.5714E-01 9.5714E-01 9.5714E-01 9.5714E-01 62 1.243E+00 1.750E+01 2.5795E-02 2.5795E-02 2.5795E-02 9.7453E-01 9.7453E-01 9.7453E-01 9.7453E-01 63 1.278E+00 2.000E+01 1.5190E-02 1.5190E-02 1.5190E-02 9.8492E-01 9.8492E-01 9.8492E-01 9.8492E-01 64 1.347E+00 2.500E+01 5.2679E-03 5.2679E-03 5.2679E-03 9.9475E-01 9.9475E-01 9.9475E-01 9.9475E-01 65 1.417E+00 3.000E+01 1.8269E-03 1.8269E-03 1.8269E-03 9.9817E-01 9.9817E-01 9.9817E-01 9.9817E-01 66 1.486E+00 3.500E+01 6.3354E-04 6.3354E-04 6.3354E-04 9.9937E-01 9.9937E-01 9.9937E-01 9.9937E-01 67 4.000E+00 0.000E+00 1.0000E+00 1.0000E+00 1.0000E+00 3.6788E-01 3.6788E-01 3.6788E-01 3.6788E-01 68 1.001E+00 1.000E-01 9.8390E-01 9.8390E-01 9.8390E-01 3.7385E-01 3.7385E-01 3.7385E-01 3.7385E-01 69 1.002E+00 2.500E-01 9.5929E-01 9.5929E-01 9.5929E-01 3.8316E-01 3.8316E-01 3.8316E-01 3.8316E-01 70 1.003E+00 5.000E-01 9.1745E-01 9.1745E-01 9.1745E-01 3.9954E-01 3.9954E-01 3.9954E-01 3.9954E-01 71 1.007E+00 1.000E+00 8.3278E-01 8.3278E-01 8.3278E-01 4.3484E-01 4.3484E-01 4.3484E-01 4.3484E-01 72 1.010E+00 1.500E+00 7.4981E-01 7.4981E-01 7.4981E-01 4.7246E-01 4.7246E-01 4.7246E-01 4.7246E-01 73 1.014E+00 2.000E+00 6.7093E-01 6.7093E-01 6.7093E-01 5.1123E-01 5.1123E-01 5.1123E-01 5.1123E-01 74 1.021E+00 3.000E+00 5.3020E-01 5.3020E-01 5.3020E-01 5.8849E-01 5.8849E-01 5.8849E-01 5.8849E-01 75 1.028E+00 4.000E+00 4.1432E-01 4.1432E-01 4.1432E-01 6.6079E-01 6.6079E-01 6.6079E-01 6.6079E-01 76 1.035E+00 5.000E+00 3.2165E-01 3.2165E-01 3.2165E-01 7.2495E-01 7.2495E-01 7.2495E-01 7.2495E-01 77 1.042E+00 6.000E+00 2.4876E-01 2.4876E-01 2.4876E-01 7.7977E-01 7.7977E-01 7.7977E-01 7.7977E-01 78 1.049E+00 7.000E+00 1.9196E-01 1.9196E-01 1.9196E-01 8.2534E-01 8.2534E-01 8.2534E-01 8.2534E-01 79 1.056E+00 8.000E+00 1.4794E-01 1.4794E-01 1.4794E-01 8.6248E-01 8.6248E-01 8.6248E-01 8.6248E-01 80 1.062E+00 9.000E+00 1.1393E-01 1.1393E-01 1.1393E-01 8.9232E-01 8.9232E-01 8.9232E-01 8.9232E-01 81 1.069E+00 1.000E+01 8.7702E-02 8.7702E-02 8.7702E-02 9.1603E-01 9.1603E-01 9.1603E-01 9.1603E-01 82 1.087E+00 1.250E+01 4.5554E-02 4.5554E-02 4.5554E-02 9.5547E-01 9.5547E-01 9.5547E-01 9.5547E-01 83 1.104E+00 1.500E+01 2.3650E-02 2.3650E-02 2.3650E-02 9.7663E-01 9.7663E-01 9.7663E-01 9.7663E-01 84 1.122E+00 1.750E+01 1.2277E-02 1.2277E-02 1.2277E-02 9.8780E-01 9.8780E-01 9.8780E-01 9.8780E-01 85 1.139E+00 2.000E+01 6.3729E-03 6.3729E-03 6.3729E-03 9.9365E-01 9.9365E-01 9.9365E-01 9.9365E-01 86 1.174E+00 2.500E+01 1.7172E-03 1.7172E-03 1.7172E-03 9.9828E-01 9.9828E-01 9.9828E-01 9.9828E-01 87 1.208E+00 3.000E+01 4.6270E-04 4.6270E-04 4.6270E-04 9.9954E-01 9.9954E-01 9.9954E-01 9.9954E-01 88 1.243E+00 3.500E+01 1.2467E-04 1.2467E-04 1.2467E-04 9.9988E-01 9.9988E-01 9.9988E-01 9.9988E-01 89 4.000E+00 0.000E+00 1.0000E+00 1.0000E+00 1.0000E+00 3.6788E-01 3.6788E-01 3.6788E-01 3.6788E-01 90 1.000E+00 1.000E-01 9.8390E-01 9.8390E-01 9.8390E-01 3.7385E-01 3.7385E-01 3.7385E-01 3.7385E-01 91 1.001E+00 2.500E-01 9.5926E-01 9.5926E-01 9.5926E-01 3.8318E-01 3.8318E-01 3.8318E-01 3.8318E-01 92 1.002E+00 5.000E-01 9.1720E-01 9.1720E-01 9.1720E-01 3.9964E-01 3.9964E-01 3.9964E-01 3.9964E-01 93 1.003E+00 1.000E+00 8.3113E-01 8.3113E-01 8.3113E-01 4.3555E-01 4.3555E-01 4.3555E-01 4.3555E-01 94 1.005E+00 1.500E+00 7.4527E-01 7.4527E-01 7.4527E-01 4.7461E-01 4.7461E-01 4.7461E-01 4.7461E-01 95 1.007E+00 2.000E+00 6.6219E-01 6.6219E-01 6.6219E-01 5.1572E-01 5.1572E-01 5.1572E-01 5.1572E-01 96 1.010E+00 3.000E+00 5.1099E-01 5.1099E-01 5.1099E-01 5.9990E-01 5.9990E-01 5.9990E-01 5.9990E-01 97 1.014E+00 4.000E+00 3.8489E-01 3.8489E-01 3.8489E-01 6.8052E-01 6.8052E-01 6.8052E-01 6.8052E-01 98 1.017E+00 5.000E+00 2.8466E-01 2.8466E-01 2.8466E-01 7.5227E-01 7.5227E-01 7.5227E-01 7.5227E-01 99 1.021E+00 6.000E+00 2.0764E-01 2.0764E-01 2.0764E-01 8.1250E-01 8.1250E-01 8.1250E-01 8.1250E-01 100 1.024E+00 7.000E+00 1.4989E-01 1.4989E-01 1.4989E-01 8.6080E-01 8.6080E-01 8.6080E-01 8.6080E-01 101 1.028E+00 8.000E+00 1.0734E-01 1.0734E-01 1.0734E-01 8.9822E-01 8.9822E-01 8.9822E-01 8.9822E-01 102 1.031E+00 9.000E+00 7.6417E-02 7.6417E-02 7.6417E-02 9.2643E-01 9.2643E-01 9.2643E-01 9.2643E-01 103 1.035E+00 1.000E+01 5.4155E-02 5.4155E-02 5.4155E-02 9.4728E-01 9.4728E-01 9.4728E-01 9.4728E-01 104 1.043E+00 1.250E+01 2.2596E-02 2.2596E-02 2.2596E-02 9.7766E-01 9.7766E-01 9.7766E-01 9.7766E-01 105 1.052E+00 1.500E+01 9.3248E-03 9.3248E-03 9.3248E-03 9.9072E-01 9.9072E-01 9.9072E-01 9.9072E-01 106 1.061E+00 1.750E+01 3.8271E-03 3.8271E-03 3.8271E-03 9.9618E-01 9.9618E-01 9.9618E-01 9.9618E-01 107 1.069E+00 2.000E+01 1.5664E-03 1.5664E-03 1.5664E-03 9.9843E-01 9.9843E-01 9.9843E-01 9.9843E-01 108 1.087E+00 2.500E+01 2.6153E-04 2.6153E-04 2.6153E-04 9.9974E-01 9.9974E-01 9.9974E-01 9.9974E-01 109 1.104E+00 3.000E+01 4.3599E-05 4.3599E-05 4.3599E-05 9.9996E-01 9.9996E-01 9.9996E-01 9.9996E-01 110 1.122E+00 3.500E+01 7.2654E-06 7.2654E-06 7.2654E-06 9.9999E-01 9.9999E-01 9.9999E-01 9.9999E-01 111 4.000E+00 0.000E+00 1.0000E+00 1.0000E+00 1.0000E+00 3.6788E-01 3.6788E-01 3.6788E-01 3.6788E-01 112 1.000E+00 1.000E-01 9.8389E-01 9.8389E-01 9.8389E-01 3.7385E-01 3.7385E-01 3.7385E-01 3.7385E-01 113 1.000E+00 2.500E-01 9.5923E-01 9.5923E-01 9.5923E-01 3.8319E-01 3.8319E-01 3.8319E-01 3.8319E-01 114 1.001E+00 5.000E-01 9.1704E-01 9.1704E-01 9.1704E-01 3.9970E-01 3.9970E-01 3.9970E-01 3.9970E-01 115 1.001E+00 1.000E+00 8.3004E-01 8.3004E-01 8.3004E-01 4.3603E-01 4.3603E-01 4.3603E-01 4.3603E-01 116 1.002E+00 1.500E+00 7.4212E-01 7.4212E-01 7.4212E-01 4.7610E-01 4.7610E-01 4.7610E-01 4.7610E-01 117 1.003E+00 2.000E+00 6.5589E-01 6.5589E-01 6.5589E-01 5.1898E-01 5.1898E-01 5.1898E-01 5.1898E-01 118 1.004E+00 3.000E+00 4.9621E-01 4.9621E-01 4.9621E-01 6.0884E-01 6.0884E-01 6.0884E-01 6.0884E-01 119 1.006E+00 4.000E+00 3.6122E-01 3.6122E-01 3.6122E-01 6.9683E-01 6.9683E-01 6.9683E-01 6.9683E-01 120 1.007E+00 5.000E+00 2.5414E-01 2.5414E-01 2.5414E-01 7.7558E-01 7.7558E-01 7.7558E-01 7.7558E-01 121 1.008E+00 6.000E+00 1.7350E-01 1.7350E-01 1.7350E-01 8.4072E-01 8.4072E-01 8.4072E-01 8.4072E-01 122 1.010E+00 7.000E+00 1.1533E-01 1.1533E-01 1.1533E-01 8.9107E-01 8.9107E-01 8.9107E-01 8.9107E-01 123 1.011E+00 8.000E+00 7.4870E-02 7.4870E-02 7.4870E-02 9.2786E-01 9.2786E-01 9.2786E-01 9.2786E-01 124 1.012E+00 9.000E+00 4.7600E-02 4.7600E-02 4.7600E-02 9.5352E-01 9.5352E-01 9.5352E-01 9.5352E-01 125 1.014E+00 1.000E+01 2.9708E-02 2.9708E-02 2.9708E-02 9.7073E-01 9.7073E-01 9.7073E-01 9.7073E-01 126 1.017E+00 1.250E+01 8.5443E-03 8.5443E-03 8.5443E-03 9.9149E-01 9.9149E-01 9.9149E-01 9.9149E-01 127 1.021E+00 1.500E+01 2.2777E-03 2.2777E-03 2.2777E-03 9.9772E-01 9.9772E-01 9.9772E-01 9.9772E-01 128 1.024E+00 1.750E+01 5.7408E-04 5.7408E-04 5.7408E-04 9.9943E-01 9.9943E-01 9.9943E-01 9.9943E-01 129 1.028E+00 2.000E+01 1.3883E-04 1.3883E-04 1.3883E-04 9.9986E-01 9.9986E-01 9.9986E-01 9.9986E-01 130 1.035E+00 2.500E+01 7.4693E-06 7.4693E-06 7.4693E-06 9.9999E-01 9.9999E-01 9.9999E-01 9.9999E-01 131 1.042E+00 3.000E+01 3.7545E-07 3.7545E-07 3.7545E-07 1.0000E+00 1.0000E+00 1.0000E+00 1.0000E+00 132 1.049E+00 3.500E+01 1.8186E-08 1.8186E-08 1.8186E-08 1.0000E+00 1.0000E+00 1.0000E+00 1.0000E+00 133 4.000E+00 0.000E+00 1.0000E+00 1.0000E+00 1.0000E+00 3.6788E-01 3.6788E-01 3.6788E-01 3.6788E-01 134 1.000E+00 1.000E-01 9.8389E-01 9.8389E-01 9.8389E-01 3.7385E-01 3.7385E-01 3.7385E-01 3.7385E-01 135 1.000E+00 2.500E-01 9.5923E-01 9.5923E-01 9.5923E-01 3.8319E-01 3.8319E-01 3.8319E-01 3.8319E-01 136 1.000E+00 5.000E-01 9.1697E-01 9.1697E-01 9.1697E-01 3.9973E-01 3.9973E-01 3.9973E-01 3.9973E-01 137 1.001E+00 1.000E+00 8.2957E-01 8.2957E-01 8.2957E-01 4.3624E-01 4.3624E-01 4.3624E-01 4.3624E-01 138 1.001E+00 1.500E+00 7.4074E-01 7.4074E-01 7.4074E-01 4.7676E-01 4.7676E-01 4.7676E-01 4.7676E-01 139 1.001E+00 2.000E+00 6.5307E-01 6.5307E-01 6.5307E-01 5.2045E-01 5.2045E-01 5.2045E-01 5.2045E-01 140 1.002E+00 3.000E+00 4.8934E-01 4.8934E-01 4.8934E-01 6.1303E-01 6.1303E-01 6.1303E-01 6.1303E-01 141 1.002E+00 4.000E+00 3.4997E-01 3.4997E-01 3.4997E-01 7.0471E-01 7.0471E-01 7.0471E-01 7.0471E-01 142 1.003E+00 5.000E+00 2.3954E-01 2.3954E-01 2.3954E-01 7.8699E-01 7.8699E-01 7.8699E-01 7.8699E-01 143 1.003E+00 6.000E+00 1.5730E-01 1.5730E-01 1.5730E-01 8.5445E-01 8.5445E-01 8.5445E-01 8.5445E-01 144 1.004E+00 7.000E+00 9.9334E-02 9.9334E-02 9.9334E-02 9.0544E-01 9.0544E-01 9.0544E-01 9.0544E-01 145 1.004E+00 8.000E+00 6.0459E-02 6.0459E-02 6.0459E-02 9.4133E-01 9.4133E-01 9.4133E-01 9.4133E-01 146 1.005E+00 9.000E+00 3.5539E-02 3.5539E-02 3.5539E-02 9.6508E-01 9.6508E-01 9.6508E-01 9.6508E-01 147 1.005E+00 1.000E+01 2.0216E-02 2.0216E-02 2.0216E-02 9.7999E-01 9.7999E-01 9.7999E-01 9.7999E-01 148 1.007E+00 1.250E+01 4.3246E-03 4.3246E-03 4.3246E-03 9.9568E-01 9.9568E-01 9.9568E-01 9.9568E-01 149 1.008E+00 1.500E+01 7.8214E-04 7.8214E-04 7.8214E-04 9.9922E-01 9.9922E-01 9.9922E-01 9.9922E-01 150 1.009E+00 1.750E+01 1.2231E-04 1.2231E-04 1.2231E-04 9.9988E-01 9.9988E-01 9.9988E-01 9.9988E-01 151 1.011E+00 2.000E+01 1.6865E-05 1.6865E-05 1.6865E-05 9.9998E-01 9.9998E-01 9.9998E-01 9.9998E-01 152 1.014E+00 2.500E+01 2.3444E-07 2.3444E-07 2.3444E-07 1.0000E+00 1.0000E+00 1.0000E+00 1.0000E+00 153 1.016E+00 3.000E+01 2.3430E-09 2.3430E-09 2.3430E-09 1.0000E+00 1.0000E+00 1.0000E+00 1.0000E+00 154 1.019E+00 3.500E+01 1.8265E-11 1.8265E-11 1.8265E-11 1.0000E+00 1.0000E+00 1.0000E+00 1.0000E+00 --------------------------------------------------------------------------------------------------------------------- NOTE: TCP={probability no cells survive}=EXP{-(expected number of surviving cells)}. TCP estimates are based on the expected number of surviving cells with and without corrections for repopulation effects. The *MAX* TCP is the peak (all time points after irradiation) estimate derived from NSC(t). RADX EXPOSURE SUMMARY ============================================================================== SCENARIO ----- DURATION ----- ------ DOSE (Gy) ----- -- DOSE RATE (Gy/h) -- NUMBER hours days Background Total Background Total* ------------------------------------------------------------------------------ 1 2.778E-13 1.157E-14 0.0000E+00 0.0000E+00 0.0000E+00 0.0000E+00 2 1.667E-01 6.944E-03 0.0000E+00 1.0000E-01 0.0000E+00 6.0000E-01 3 4.167E-01 1.736E-02 0.0000E+00 2.5000E-01 0.0000E+00 6.0000E-01 4 8.333E-01 3.472E-02 0.0000E+00 5.0000E-01 0.0000E+00 6.0000E-01 5 1.667E+00 6.944E-02 0.0000E+00 1.0000E+00 0.0000E+00 6.0000E-01 6 2.500E+00 1.042E-01 0.0000E+00 1.5000E+00 0.0000E+00 6.0000E-01 7 3.333E+00 1.389E-01 0.0000E+00 2.0000E+00 0.0000E+00 6.0000E-01 8 5.000E+00 2.083E-01 0.0000E+00 3.0000E+00 0.0000E+00 6.0000E-01 9 6.667E+00 2.778E-01 0.0000E+00 4.0000E+00 0.0000E+00 6.0000E-01 10 8.333E+00 3.472E-01 0.0000E+00 5.0000E+00 0.0000E+00 6.0000E-01 11 1.000E+01 4.167E-01 0.0000E+00 6.0000E+00 0.0000E+00 6.0000E-01 12 1.167E+01 4.861E-01 0.0000E+00 7.0000E+00 0.0000E+00 6.0000E-01 13 1.333E+01 5.556E-01 0.0000E+00 8.0000E+00 0.0000E+00 6.0000E-01 14 1.500E+01 6.250E-01 0.0000E+00 9.0000E+00 0.0000E+00 6.0000E-01 15 1.667E+01 6.944E-01 0.0000E+00 1.0000E+01 0.0000E+00 6.0000E-01 16 2.083E+01 8.681E-01 0.0000E+00 1.2500E+01 0.0000E+00 6.0000E-01 17 2.500E+01 1.042E+00 0.0000E+00 1.5000E+01 0.0000E+00 6.0000E-01 18 2.917E+01 1.215E+00 0.0000E+00 1.7500E+01 0.0000E+00 6.0000E-01 19 3.333E+01 1.389E+00 0.0000E+00 2.0000E+01 0.0000E+00 6.0000E-01 20 4.167E+01 1.736E+00 0.0000E+00 2.5000E+01 0.0000E+00 6.0000E-01 21 5.000E+01 2.083E+00 0.0000E+00 3.0000E+01 0.0000E+00 6.0000E-01 22 5.833E+01 2.431E+00 0.0000E+00 3.5000E+01 0.0000E+00 6.0000E-01 23 2.778E-13 1.157E-14 0.0000E+00 0.0000E+00 0.0000E+00 0.0000E+00 24 8.333E-02 3.472E-03 0.0000E+00 1.0000E-01 0.0000E+00 1.2000E+00 25 2.083E-01 8.681E-03 0.0000E+00 2.5000E-01 0.0000E+00 1.2000E+00 26 4.167E-01 1.736E-02 0.0000E+00 5.0000E-01 0.0000E+00 1.2000E+00 27 8.333E-01 3.472E-02 0.0000E+00 1.0000E+00 0.0000E+00 1.2000E+00 28 1.250E+00 5.208E-02 0.0000E+00 1.5000E+00 0.0000E+00 1.2000E+00 29 1.667E+00 6.944E-02 0.0000E+00 2.0000E+00 0.0000E+00 1.2000E+00 30 2.500E+00 1.042E-01 0.0000E+00 3.0000E+00 0.0000E+00 1.2000E+00 31 3.333E+00 1.389E-01 0.0000E+00 4.0000E+00 0.0000E+00 1.2000E+00 32 4.167E+00 1.736E-01 0.0000E+00 5.0000E+00 0.0000E+00 1.2000E+00 33 5.000E+00 2.083E-01 0.0000E+00 6.0000E+00 0.0000E+00 1.2000E+00 34 5.833E+00 2.431E-01 0.0000E+00 7.0000E+00 0.0000E+00 1.2000E+00 35 6.667E+00 2.778E-01 0.0000E+00 8.0000E+00 0.0000E+00 1.2000E+00 36 7.500E+00 3.125E-01 0.0000E+00 9.0000E+00 0.0000E+00 1.2000E+00 37 8.333E+00 3.472E-01 0.0000E+00 1.0000E+01 0.0000E+00 1.2000E+00 38 1.042E+01 4.340E-01 0.0000E+00 1.2500E+01 0.0000E+00 1.2000E+00 39 1.250E+01 5.208E-01 0.0000E+00 1.5000E+01 0.0000E+00 1.2000E+00 40 1.458E+01 6.076E-01 0.0000E+00 1.7500E+01 0.0000E+00 1.2000E+00 41 1.667E+01 6.944E-01 0.0000E+00 2.0000E+01 0.0000E+00 1.2000E+00 42 2.083E+01 8.681E-01 0.0000E+00 2.5000E+01 0.0000E+00 1.2000E+00 43 2.500E+01 1.042E+00 0.0000E+00 3.0000E+01 0.0000E+00 1.2000E+00 44 2.917E+01 1.215E+00 0.0000E+00 3.5000E+01 0.0000E+00 1.2000E+00 45 2.778E-13 1.157E-14 0.0000E+00 0.0000E+00 0.0000E+00 0.0000E+00 46 3.333E-02 1.389E-03 0.0000E+00 1.0000E-01 0.0000E+00 3.0000E+00 47 8.333E-02 3.472E-03 0.0000E+00 2.5000E-01 0.0000E+00 3.0000E+00 48 1.667E-01 6.944E-03 0.0000E+00 5.0000E-01 0.0000E+00 3.0000E+00 49 3.333E-01 1.389E-02 0.0000E+00 1.0000E+00 0.0000E+00 3.0000E+00 50 5.000E-01 2.083E-02 0.0000E+00 1.5000E+00 0.0000E+00 3.0000E+00 51 6.667E-01 2.778E-02 0.0000E+00 2.0000E+00 0.0000E+00 3.0000E+00 52 1.000E+00 4.167E-02 0.0000E+00 3.0000E+00 0.0000E+00 3.0000E+00 53 1.333E+00 5.556E-02 0.0000E+00 4.0000E+00 0.0000E+00 3.0000E+00 54 1.667E+00 6.944E-02 0.0000E+00 5.0000E+00 0.0000E+00 3.0000E+00 55 2.000E+00 8.333E-02 0.0000E+00 6.0000E+00 0.0000E+00 3.0000E+00 56 2.333E+00 9.722E-02 0.0000E+00 7.0000E+00 0.0000E+00 3.0000E+00 57 2.667E+00 1.111E-01 0.0000E+00 8.0000E+00 0.0000E+00 3.0000E+00 58 3.000E+00 1.250E-01 0.0000E+00 9.0000E+00 0.0000E+00 3.0000E+00 59 3.333E+00 1.389E-01 0.0000E+00 1.0000E+01 0.0000E+00 3.0000E+00 60 4.167E+00 1.736E-01 0.0000E+00 1.2500E+01 0.0000E+00 3.0000E+00 61 5.000E+00 2.083E-01 0.0000E+00 1.5000E+01 0.0000E+00 3.0000E+00 62 5.833E+00 2.431E-01 0.0000E+00 1.7500E+01 0.0000E+00 3.0000E+00 63 6.667E+00 2.778E-01 0.0000E+00 2.0000E+01 0.0000E+00 3.0000E+00 64 8.333E+00 3.472E-01 0.0000E+00 2.5000E+01 0.0000E+00 3.0000E+00 65 1.000E+01 4.167E-01 0.0000E+00 3.0000E+01 0.0000E+00 3.0000E+00 66 1.167E+01 4.861E-01 0.0000E+00 3.5000E+01 0.0000E+00 3.0000E+00 67 2.778E-13 1.157E-14 0.0000E+00 0.0000E+00 0.0000E+00 0.0000E+00 68 1.667E-02 6.944E-04 0.0000E+00 1.0000E-01 0.0000E+00 6.0000E+00 69 4.167E-02 1.736E-03 0.0000E+00 2.5000E-01 0.0000E+00 6.0000E+00 70 8.333E-02 3.472E-03 0.0000E+00 5.0000E-01 0.0000E+00 6.0000E+00 71 1.667E-01 6.944E-03 0.0000E+00 1.0000E+00 0.0000E+00 6.0000E+00 72 2.500E-01 1.042E-02 0.0000E+00 1.5000E+00 0.0000E+00 6.0000E+00 73 3.333E-01 1.389E-02 0.0000E+00 2.0000E+00 0.0000E+00 6.0000E+00 74 5.000E-01 2.083E-02 0.0000E+00 3.0000E+00 0.0000E+00 6.0000E+00 75 6.667E-01 2.778E-02 0.0000E+00 4.0000E+00 0.0000E+00 6.0000E+00 76 8.333E-01 3.472E-02 0.0000E+00 5.0000E+00 0.0000E+00 6.0000E+00 77 1.000E+00 4.167E-02 0.0000E+00 6.0000E+00 0.0000E+00 6.0000E+00 78 1.167E+00 4.861E-02 0.0000E+00 7.0000E+00 0.0000E+00 6.0000E+00 79 1.333E+00 5.556E-02 0.0000E+00 8.0000E+00 0.0000E+00 6.0000E+00 80 1.500E+00 6.250E-02 0.0000E+00 9.0000E+00 0.0000E+00 6.0000E+00 81 1.667E+00 6.944E-02 0.0000E+00 1.0000E+01 0.0000E+00 6.0000E+00 82 2.083E+00 8.681E-02 0.0000E+00 1.2500E+01 0.0000E+00 6.0000E+00 83 2.500E+00 1.042E-01 0.0000E+00 1.5000E+01 0.0000E+00 6.0000E+00 84 2.917E+00 1.215E-01 0.0000E+00 1.7500E+01 0.0000E+00 6.0000E+00 85 3.333E+00 1.389E-01 0.0000E+00 2.0000E+01 0.0000E+00 6.0000E+00 86 4.167E+00 1.736E-01 0.0000E+00 2.5000E+01 0.0000E+00 6.0000E+00 87 5.000E+00 2.083E-01 0.0000E+00 3.0000E+01 0.0000E+00 6.0000E+00 88 5.833E+00 2.431E-01 0.0000E+00 3.5000E+01 0.0000E+00 6.0000E+00 89 2.778E-13 1.157E-14 0.0000E+00 0.0000E+00 0.0000E+00 0.0000E+00 90 8.333E-03 3.472E-04 0.0000E+00 1.0000E-01 0.0000E+00 1.2000E+01 91 2.083E-02 8.681E-04 0.0000E+00 2.5000E-01 0.0000E+00 1.2000E+01 92 4.167E-02 1.736E-03 0.0000E+00 5.0000E-01 0.0000E+00 1.2000E+01 93 8.333E-02 3.472E-03 0.0000E+00 1.0000E+00 0.0000E+00 1.2000E+01 94 1.250E-01 5.208E-03 0.0000E+00 1.5000E+00 0.0000E+00 1.2000E+01 95 1.667E-01 6.944E-03 0.0000E+00 2.0000E+00 0.0000E+00 1.2000E+01 96 2.500E-01 1.042E-02 0.0000E+00 3.0000E+00 0.0000E+00 1.2000E+01 97 3.333E-01 1.389E-02 0.0000E+00 4.0000E+00 0.0000E+00 1.2000E+01 98 4.167E-01 1.736E-02 0.0000E+00 5.0000E+00 0.0000E+00 1.2000E+01 99 5.000E-01 2.083E-02 0.0000E+00 6.0000E+00 0.0000E+00 1.2000E+01 100 5.833E-01 2.431E-02 0.0000E+00 7.0000E+00 0.0000E+00 1.2000E+01 101 6.667E-01 2.778E-02 0.0000E+00 8.0000E+00 0.0000E+00 1.2000E+01 102 7.500E-01 3.125E-02 0.0000E+00 9.0000E+00 0.0000E+00 1.2000E+01 103 8.333E-01 3.472E-02 0.0000E+00 1.0000E+01 0.0000E+00 1.2000E+01 104 1.042E+00 4.340E-02 0.0000E+00 1.2500E+01 0.0000E+00 1.2000E+01 105 1.250E+00 5.208E-02 0.0000E+00 1.5000E+01 0.0000E+00 1.2000E+01 106 1.458E+00 6.076E-02 0.0000E+00 1.7500E+01 0.0000E+00 1.2000E+01 107 1.667E+00 6.944E-02 0.0000E+00 2.0000E+01 0.0000E+00 1.2000E+01 108 2.083E+00 8.681E-02 0.0000E+00 2.5000E+01 0.0000E+00 1.2000E+01 109 2.500E+00 1.042E-01 0.0000E+00 3.0000E+01 0.0000E+00 1.2000E+01 110 2.917E+00 1.215E-01 0.0000E+00 3.5000E+01 0.0000E+00 1.2000E+01 111 2.778E-13 1.157E-14 0.0000E+00 0.0000E+00 0.0000E+00 0.0000E+00 112 3.333E-03 1.389E-04 0.0000E+00 1.0000E-01 0.0000E+00 3.0000E+01 113 8.333E-03 3.472E-04 0.0000E+00 2.5000E-01 0.0000E+00 3.0000E+01 114 1.667E-02 6.944E-04 0.0000E+00 5.0000E-01 0.0000E+00 3.0000E+01 115 3.333E-02 1.389E-03 0.0000E+00 1.0000E+00 0.0000E+00 3.0000E+01 116 5.000E-02 2.083E-03 0.0000E+00 1.5000E+00 0.0000E+00 3.0000E+01 117 6.667E-02 2.778E-03 0.0000E+00 2.0000E+00 0.0000E+00 3.0000E+01 118 1.000E-01 4.167E-03 0.0000E+00 3.0000E+00 0.0000E+00 3.0000E+01 119 1.333E-01 5.556E-03 0.0000E+00 4.0000E+00 0.0000E+00 3.0000E+01 120 1.667E-01 6.944E-03 0.0000E+00 5.0000E+00 0.0000E+00 3.0000E+01 121 2.000E-01 8.333E-03 0.0000E+00 6.0000E+00 0.0000E+00 3.0000E+01 122 2.333E-01 9.722E-03 0.0000E+00 7.0000E+00 0.0000E+00 3.0000E+01 123 2.667E-01 1.111E-02 0.0000E+00 8.0000E+00 0.0000E+00 3.0000E+01 124 3.000E-01 1.250E-02 0.0000E+00 9.0000E+00 0.0000E+00 3.0000E+01 125 3.333E-01 1.389E-02 0.0000E+00 1.0000E+01 0.0000E+00 3.0000E+01 126 4.167E-01 1.736E-02 0.0000E+00 1.2500E+01 0.0000E+00 3.0000E+01 127 5.000E-01 2.083E-02 0.0000E+00 1.5000E+01 0.0000E+00 3.0000E+01 128 5.833E-01 2.431E-02 0.0000E+00 1.7500E+01 0.0000E+00 3.0000E+01 129 6.667E-01 2.778E-02 0.0000E+00 2.0000E+01 0.0000E+00 3.0000E+01 130 8.333E-01 3.472E-02 0.0000E+00 2.5000E+01 0.0000E+00 3.0000E+01 131 1.000E+00 4.167E-02 0.0000E+00 3.0000E+01 0.0000E+00 3.0000E+01 132 1.167E+00 4.861E-02 0.0000E+00 3.5000E+01 0.0000E+00 3.0000E+01 133 2.778E-13 1.157E-14 0.0000E+00 0.0000E+00 0.0000E+00 0.0000E+00 134 1.302E-03 5.425E-05 0.0000E+00 1.0000E-01 0.0000E+00 7.6800E+01 135 3.255E-03 1.356E-04 0.0000E+00 2.5000E-01 0.0000E+00 7.6800E+01 136 6.510E-03 2.713E-04 0.0000E+00 5.0000E-01 0.0000E+00 7.6800E+01 137 1.302E-02 5.425E-04 0.0000E+00 1.0000E+00 0.0000E+00 7.6800E+01 138 1.953E-02 8.138E-04 0.0000E+00 1.5000E+00 0.0000E+00 7.6800E+01 139 2.604E-02 1.085E-03 0.0000E+00 2.0000E+00 0.0000E+00 7.6800E+01 140 3.906E-02 1.628E-03 0.0000E+00 3.0000E+00 0.0000E+00 7.6800E+01 141 5.208E-02 2.170E-03 0.0000E+00 4.0000E+00 0.0000E+00 7.6800E+01 142 6.510E-02 2.713E-03 0.0000E+00 5.0000E+00 0.0000E+00 7.6800E+01 143 7.813E-02 3.255E-03 0.0000E+00 6.0000E+00 0.0000E+00 7.6800E+01 144 9.115E-02 3.798E-03 0.0000E+00 7.0000E+00 0.0000E+00 7.6800E+01 145 1.042E-01 4.340E-03 0.0000E+00 8.0000E+00 0.0000E+00 7.6800E+01 146 1.172E-01 4.883E-03 0.0000E+00 9.0000E+00 0.0000E+00 7.6800E+01 147 1.302E-01 5.425E-03 0.0000E+00 1.0000E+01 0.0000E+00 7.6800E+01 148 1.628E-01 6.782E-03 0.0000E+00 1.2500E+01 0.0000E+00 7.6800E+01 149 1.953E-01 8.138E-03 0.0000E+00 1.5000E+01 0.0000E+00 7.6800E+01 150 2.279E-01 9.494E-03 0.0000E+00 1.7500E+01 0.0000E+00 7.6800E+01 151 2.604E-01 1.085E-02 0.0000E+00 2.0000E+01 0.0000E+00 7.6800E+01 152 3.255E-01 1.356E-02 0.0000E+00 2.5000E+01 0.0000E+00 7.6800E+01 153 3.906E-01 1.628E-02 0.0000E+00 3.0000E+01 0.0000E+00 7.6800E+01 154 4.557E-01 1.899E-02 0.0000E+00 3.5000E+01 0.0000E+00 7.6800E+01 ------------------------------------------------------------------------------ * Dose rate is the delivered dose divided by the duration of the exposure scenario. Total VC execution time (min): 1.87667E-02 VC 2.00I 13-JUL-2003 14-JUL-2003 04:12:46 PM